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ONTOLOGY REPORT - ANNOTATIONS

Term:myeloid cell activation involved in immune response
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Accession:GO:0002275 term browser browse the term
Definition:A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: myeloid cell activation during immune response


show annotations for term's descendants           Sort by:
basophil activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5660449|PMID:25692702)		 UniProt
Ensembl
RGD		 PMID:25692702 GO_REF:0000024 GO_REF:0000107 MGI:5660449 NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G Kars1 lysyl-tRNA synthetase 1 involved_in ISO
IBA
IMP		 UniProtKB:Q5XIM7 (PMID:19524539)
GO_REF:0000033		 RGD
GO_Central		 PMID:19524539 PMID:19524539 GO_REF:0000033, RGD:12793003 NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632 		JBrowse link
basophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha IMP RGD PMID:17122963 RGD:2306407 NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337 		JBrowse link
eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
ISS		 (PMID:10706735)
GO_REF:0000024		 RGD
UniProt		 PMID:10706735 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Fcer1a Fc epsilon receptor Ia involved_in ISO (PMID:8114916) RGD PMID:8114916 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:8114916) RGD PMID:8114916
G Vamp2 vesicle-associated membrane protein 2 involved_in ISO
IEA		 (PMID:16677249)
GO_REF:0000107		 RGD
Ensembl		 PMID:16677249 GO_REF:0000107 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in IDA
ISO		 PMID:14993220
(PMID:16677249)		 RGD PMID:16677249 PMID:14993220 RGD:8553828 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 NOT|involved_in ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:12220673 RGD:1600535 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO MGI:6695900 (PMID:32238914) RGD PMID:32238914 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1351429|PMID:10618388)		 Ensembl
RGD		 PMID:10618388 GO_REF:0000107 MGI:1351429 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Snap23 synaptosome associated protein 23 involved_in ISO
IEA		 (PMID:18253931)
GO_REF:0000107		 RGD
Ensembl		 PMID:18253931 GO_REF:0000107 NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta IMP RGD PMID:12499633 RGD:1625716 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
macrophage activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dysf dysferlin acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:18276788)
MGI:1857883 (PMID:18276788)
GO_REF:0000033		 RGD
GO_Central		 PMID:18276788 GO_REF:0000033 NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Ifnb1 interferon beta 1 involved_in IDA PMID:10496312 UniProt PMID:10496312 RGD:12903242 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:30634164) RGD PMID:30634164 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il33 interleukin 33 involved_in ISO (MGI:5751675|PMID:21494550) RGD PMID:21494550 MGI:5751675 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:3807766|PMID:12932360)
(PMID:24120359)		 UniProt
GO_Central
Ensembl
RGD		 PMID:12932360 PMID:24120359 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3807766 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Nmi N-myc (and STAT) interactor involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA		 (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Prkce protein kinase C, epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3609215 (PMID:11696589)		 Ensembl
RGD		 PMID:11696589 GO_REF:0000107 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Sbno2 strawberry notch homolog 2 involved_in ISO
IBA		 (PMID:18025162)
GO_REF:0000033
(MGI:3777518|PMID:18025162)		 RGD
GO_Central		 PMID:18025162 GO_REF:0000033 MGI:3777518 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527 		JBrowse link
G Sucnr1 succinate receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3828087 (PMID:27481132)		 Ensembl
RGD		 PMID:27481132 GO_REF:0000107 NCBI chr 2:144,219,066...144,230,568
Ensembl chr 2:144,219,122...144,230,034 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
IBA
ISO
ISS		 GO_REF:0000107
GO_REF:0000033
(MGI:3693026|PMID:17086186)
GO_REF:0000024		 Ensembl
GO_Central
RGD
UniProt		 PMID:17086186 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3693026 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794 (PMID:12872135) RGD PMID:12872135 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:7387167|PMID:29849090) RGD PMID:29849090 MGI:7387167 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (PMID:24218451) RGD PMID:24218451 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3693026|PMID:17086186) RGD PMID:17086186 MGI:3693026 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor acts_upstream_of ISO (PMID:11454903) RGD PMID:11454903 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Cbl Cbl proto-oncogene IEP RGD PMID:18243321 RGD:11576314 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cd300a Cd300a molecule acts_upstream_of ISO (PMID:12874256) RGD PMID:12874256 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Chga chromogranin A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21214543)		 UniProt
Ensembl
RGD		 PMID:21214543 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (MGI:2179131|PMID:10744659) RGD PMID:10744659 MGI:2179131 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208 		JBrowse link
G Cplx2 complexin 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855 		JBrowse link
G Fcer1a Fc epsilon receptor Ia involved_in
acts_upstream_of		 ISO (PMID:8551243)
(PMID:9000133)		 RGD PMID:8551243 PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Gpr15lg G protein-coupled receptor 15 ligand involved_in ISO
ISS		 (PMID:35704588)
GO_REF:0000024		 RGD
UniProt		 PMID:35704588 GO_REF:0000024 NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876 		JBrowse link
G Grp gastrin releasing peptide involved_in ISS
ISO		 GO_REF:0000024
(MGI:6872268|PMID:21933692)		 UniProt
RGD		 PMID:21933692 GO_REF:0000024 MGI:6872268 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:33840121), (PMID:8551243) RGD PMID:8551243 PMID:33840121
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Lat linker for activation of T cells involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4461821|PMID:20526344)		 UniProt
RGD		 PMID:20526344 GO_REF:0000024 MGI:4461821 NCBI chr10:91,684,288...91,705,284
Ensembl chr10:91,687,831...91,705,282 		JBrowse link
G Mrgprx2 MAS related GPR family member X2 involved_in ISO (PMID:22069323) RGD PMID:22069323 NCBI chr 1:98,116,192...98,135,534 JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5586645|PMID:24586680)		 UniProt
RGD		 PMID:24586680 GO_REF:0000024 MGI:5586645 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (PMID:23624557) RGD PMID:23624557 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Ptgdr prostaglandin D2 receptor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
G Ptgdrl1 prostaglandin D2 receptor-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:18,072,357...18,081,452
Ensembl chr15:18,072,361...18,081,437 		JBrowse link
G Ptgds prostaglandin D2 synthase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Rab44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO MGI:6695900 (PMID:32238914) RGD PMID:32238914 NCBI chr20:7,164,576...7,198,473
Ensembl chr20:7,164,720...7,198,468 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of ISO MGI:3051384 (PMID:15235600) RGD PMID:15235600 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386261 (PMID:17190838)		 Ensembl
RGD		 PMID:17190838 GO_REF:0000107 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 involved_in IEA
ISO		 GO_REF:0000107
MGI:5608917 (PMID:31534133)		 Ensembl
RGD		 PMID:31534133 GO_REF:0000107 NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2384078 (PMID:9000133)		 Ensembl
RGD		 PMID:9000133 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tac4 tachykinin precursor 4 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156 		JBrowse link
microglial cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(MGI:4421471|PMID:20026663)		 UniProt
RGD		 PMID:20026663 GO_REF:0000024 MGI:4421471 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5008219|PMID:21349253)		 Ensembl
RGD		 PMID:21349253 GO_REF:0000107 MGI:5008219 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6201658|PMID:30232263) RGD PMID:30232263 MGI:6201658 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IBA		 (MGI:5638298|PMID:25690660)
GO_REF:0000033		 RGD
GO_Central		 PMID:25690660 GO_REF:0000033 MGI:5638298 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
monocyte activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dysf dysferlin acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:18276788)
MGI:1857883 (PMID:18276788)
GO_REF:0000033		 RGD
GO_Central		 PMID:18276788 GO_REF:0000033 NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709 		JBrowse link
myeloid dendritic cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dock2 dedicator of cytokinesis 2 involved_in ISO (MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:5291858 NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:5291858 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:16317102) RGD PMID:16317102 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 involved_in ISO
ISS		 (MGI:3699670|PMID:14662900)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:14662900 GO_REF:0000024 MGI:3699670 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
negative regulation of mast cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:16339535) RGD PMID:16339535 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5660449|PMID:25692702)		 UniProt
Ensembl
RGD		 PMID:25692702 GO_REF:0000024 GO_REF:0000107 MGI:5660449 NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:3694314|PMID:16731527)		 UniProt
RGD		 PMID:16731527 GO_REF:0000024 MGI:3694314 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6827314|PMID:10026201)		 Ensembl
RGD		 PMID:10026201 GO_REF:0000107 MGI:6827314 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in
acts_upstream_of_or_within		 ISO (PMID:16339535)
(PMID:12874256)		 RGD PMID:12874256 PMID:16339535 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076 		JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:2179135 (PMID:18421012) RGD PMID:18421012 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2653910 (PMID:15944273)		 Ensembl
RGD		 PMID:15944273 GO_REF:0000107 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (PMID:15235600) RGD PMID:15235600 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:88141 (PMID:19703997) RGD PMID:19703997 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:107771 (PMID:19703997) RGD PMID:19703997 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6381024|PMID:30911105) RGD PMID:30911105 MGI:6381024 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
neutrophil activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnase1 deoxyribonuclease 1 involved_in ISS
ISO		 PMID:29191910
(MGI:6094744|PMID:29191910)		 RGD PMID:29191910 PMID:29191910 MGI:6094744, RGD:13464261 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 involved_in ISS
ISO		 PMID:29191910
(MGI:6094744|PMID:29191910)		 RGD PMID:29191910 PMID:29191910 MGI:6094744, RGD:13464261 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in ISO
IBA		 (MGI:3693026|PMID:17086186)
GO_REF:0000033		 RGD
GO_Central		 PMID:17086186 GO_REF:0000033 MGI:3693026 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:104696 (PMID:22419116) RGD PMID:22419116 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108005 (PMID:22419116)		 Ensembl
RGD		 PMID:22419116 GO_REF:0000107 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
IBA
ISO
ISS		 GO_REF:0000107
GO_REF:0000033
(MGI:3693026|PMID:17086186)
GO_REF:0000024		 Ensembl
GO_Central
RGD
UniProt		 PMID:17086186 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3693026 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IBA		 (MGI:3693026|PMID:17086186)
GO_REF:0000033		 RGD
GO_Central		 PMID:17086186 GO_REF:0000033 MGI:3693026 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase acts_upstream_of ISO MGI:88141 (PMID:19703997) RGD PMID:19703997 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505 		JBrowse link
G Anxa3 annexin A3 involved_in ISO (PMID:9550422) RGD PMID:9550422 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of ISO MGI:107771 (PMID:19703997) RGD PMID:19703997 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Myo1f myosin IF acts_upstream_of_or_within ISO MGI:3664779 (PMID:17023661) RGD PMID:17023661 NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing NOT|involved_in ISO (MGI:6103777|PMID:28779020) RGD PMID:28779020 MGI:6103777 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (PMID:23042080) RGD PMID:23042080 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164 		JBrowse link
G Stxbp2 syntaxin binding protein 2 involved_in ISO
IEA		 (PMID:18588921)
GO_REF:0000107		 RGD
Ensembl		 PMID:18588921 GO_REF:0000107 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in ISO (PMID:18588921) RGD PMID:18588921 NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:16677249) RGD PMID:16677249 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in IDA
ISO		 PMID:14993220
(PMID:16677249)		 RGD PMID:16677249 PMID:14993220 RGD:8553828 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 NOT|involved_in ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11714832) RGD PMID:11714832 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A involved_in IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)		 RGD PMID:23624557 MGI:5492190 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18253931)		 Ensembl
RGD		 PMID:18253931 GO_REF:0000107 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
positive regulation of mast cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor acts_upstream_of_or_within ISO (PMID:11454903) RGD PMID:11454903 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO MGI:2155986 (PMID:12817016) RGD PMID:12817016 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:2384004 (PMID:14764707) RGD PMID:14764707 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294498|PMID:21746961)		 UniProt
RGD		 PMID:21746961 GO_REF:0000024 MGI:5294498 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Gab2 GRB2-associated binding protein 2 involved_in ISO
ISS		 (MGI:2137187|PMID:11449275)
GO_REF:0000024		 RGD
UniProt		 PMID:11449275 GO_REF:0000024 MGI:2137187 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO MGI:1931804|MGI:96556 (PMID:15944273) RGD PMID:15944273 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:1857195|MGI:96541 (PMID:15944273) RGD PMID:15944273 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:1861951 (PMID:15944273) RGD PMID:15944273 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310 		JBrowse link
G Nppc natriuretic peptide C involved_in IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:2384078 (PMID:9000133)
GO_REF:0000107		 RGD
Ensembl		 PMID:9000133 PMID:16861349 GO_REF:0000107, RGD:2299903 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd177 CD177 molecule involved_in ISO
IBA		 UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407)
GO_REF:0000033		 RGD
GO_Central		 PMID:21193407 GO_REF:0000033 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621 		JBrowse link
G Cd177l2 CD177 molecule like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:80,323,188...80,328,311
Ensembl chr 1:80,323,863...80,328,311 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Lypd10 Ly6/PLAUR domain containing 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:80,273,019...80,278,238
Ensembl chr 1:80,273,019...80,278,219 		JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:2829894 RGD:10041060 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx6 sorting nexin 6 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT|involved_in ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751 		JBrowse link
regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ferry3 FERRY endosomal RAB5 effector complex subunit 3 involved_in IDA
IBA		 PMID:25122211
GO_REF:0000033		 GO_Central PMID:25122211 GO_REF:0000033, RGD:10047193 NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:19001085) RGD PMID:19001085 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO
ISS		 (MGI:3703139|PMID:16272347)
GO_REF:0000024		 RGD
UniProt		 PMID:16272347 GO_REF:0000024 MGI:3703139 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA		 (MGI:5298334|PMID:21063107)
GO_REF:0000107		 RGD
Ensembl		 PMID:21063107 GO_REF:0000107 MGI:5298334 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO (MGI:3655336|PMID:10843388) RGD PMID:10843388 MGI:3655336 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:12482918 RGD:2312429 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458 		JBrowse link
G Unc13d unc-13 homolog D involved_in ISO
IEA		 (PMID:15548590)
GO_REF:0000107		 RGD
Ensembl		 PMID:15548590 GO_REF:0000107 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687 		JBrowse link
regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pram1 PML-RARA regulated adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3579812 (PMID:15572693) RGD PMID:15572693 NCBI chr 7:14,428,548...14,438,081
Ensembl chr 7:14,420,165...14,438,166 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4414596|PMID:19797524)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19797524 GO_REF:0000024 GO_REF:0000107 MGI:4414596 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule acts_upstream_of_or_within ISO (PMID:12874256) RGD PMID:12874256 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1351429|PMID:10618388)		 Ensembl
RGD		 PMID:10618388 GO_REF:0000107 MGI:1351429 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19870
    immune system process 2843
      leukocyte activation 1041
        leukocyte activation involved in immune response 323
          myeloid cell activation involved in immune response 115
            basophil activation involved in immune response + 3
            eosinophil activation involved in immune response + 9
            macrophage activation involved in immune response + 21
            mast cell activation involved in immune response + 67
            monocyte activation involved in immune response 1
            myeloid dendritic cell activation involved in immune response + 3
            neutrophil activation involved in immune response + 26
Path 2
Term Annotations click to browse term
  biological_process 19870
    cellular process 18312
      cell activation 1192
        leukocyte activation 1041
          myeloid leukocyte activation 285
            myeloid cell activation involved in immune response 115
              basophil activation involved in immune response + 3
              eosinophil activation involved in immune response + 9
              macrophage activation involved in immune response + 21
              mast cell activation involved in immune response + 67
              monocyte activation involved in immune response 1
              myeloid dendritic cell activation involved in immune response + 3
              neutrophil activation involved in immune response + 26
paths to the root