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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation

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positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IEA
ISO		 GO_REF:0000107
(MGI:3776334|PMID:11454903)		 Ensembl
RGD		 PMID:11454903 GO_REF:0000107 MGI:3776334 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365 		JBrowse link
G Adora3 adenosine A3 receptor ISO MGI:2155986 (MGI:2664591|PMID:12817016) RGD PMID:12817016 MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO MGI:2384004 (MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:3029067 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISS
ISO		 GO_REF:0000024
(MGI:5294498|PMID:21746961)		 UniProt
RGD		 PMID:21746961 GO_REF:0000024 MGI:5294498 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745 		JBrowse link
G Gab2 GRB2-associated binding protein 2 ISS
ISO		 GO_REF:0000024
(MGI:2137187|PMID:11449275)		 UniProt
RGD		 PMID:11449275 GO_REF:0000024 MGI:2137187 NCBI chr 1:162,082,876...162,283,379
Ensembl chr 1:162,083,030...162,279,727 		JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066 		JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Il13 interleukin 13 ISO MGI:1931804|MGI:96556 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466 		JBrowse link
G Il4 interleukin 4 ISO
IBA		 MGI:1857195|MGI:96541 (MGI:3589858|PMID:15944273)
PMID:21873635		 RGD PMID:15944273, PMID:21873635 MGI:3589858, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il4r interleukin 4 receptor ISO MGI:1861951 (MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:3589858 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386 		JBrowse link
G Nppc natriuretic peptide C IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636 		JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730 		JBrowse link
G Sphk2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:3703830 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277 		JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417 		JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175 		JBrowse link
G Syk spleen associated tyrosine kinase IMP
IBA
ISO
IEA		 PMID:21873635
MGI:2384078 (MGI:85068|PMID:9000133)
GO_REF:0000107		 RGD
Ensembl		 PMID:9000133, PMID:16861349, PMID:21873635 GO_REF:0000107 MGI:85068, RGD:2299903, RGD:13792537 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Pla2g3 phospholipase A2, group III ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)		 RGD PMID:23624557 MGI:5492190 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614 		JBrowse link
G Snx4 sorting nexin 4 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:70,693,381...70,753,620
Ensembl chr11:70,693,366...70,753,632 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IEA
ISO		 GO_REF:0000107
(PMID:18253931)		 Ensembl
RGD		 PMID:18253931 GO_REF:0000107 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    immune system process 2828
      positive regulation of immune system process 983
        positive regulation of immune response 626
          positive regulation of mast cell activation involved in immune response 24
            positive regulation of mast cell degranulation 24
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in other organism 0
Path 2
Term Annotations click to browse term
  biological_process 20044
    localization 6483
      establishment of localization 4908
        transport 4745
          secretion 1158
            secretion by cell 958
              exocytosis 428
                regulated exocytosis 294
                  leukocyte degranulation 91
                    regulation of leukocyte degranulation 61
                      positive regulation of leukocyte degranulation 41
                        positive regulation of mast cell degranulation 24
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in other organism 0
paths to the root