|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases activity increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein]; AKT1 mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein]; arsenic trichloride promotes the reaction [AKT1 protein binds to FLNA protein modified form]; arsenic trichloride promotes the reaction [AKT1 protein modified form binds to FLNA protein modified form]; pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein] MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein]; MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:22696236 PMID:25944616 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of APP mRNA |
CTD |
PMID:35809665 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6 promoter]; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of and results in increased cleavage of ATF6 protein; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ATF6 mRNA; NFE2L2 protein affects the reaction [[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ATF6 mRNA] |
CTD |
PMID:35625704 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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|
G |
Atf6b |
activating transcription factor 6 beta |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6B promoter]; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of and results in increased cleavage of ATF6B protein; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ATF6B mRNA; NFE2L2 protein affects the reaction [[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ATF6B mRNA] |
CTD |
PMID:35625704 |
|
NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of ATP5F1A mRNA |
CTD |
PMID:35809665 |
|
NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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|
G |
Atp5f1c |
ATP synthase F1 subunit gamma |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of ATP5F1C mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of ATP5F1C mRNA |
CTD |
PMID:35809665 |
|
NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
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|
G |
Atp5mc3 |
ATP synthase membrane subunit c locus 3 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of ATP5MC3 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
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|
G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of CASP12 mRNA |
CTD |
PMID:34091186 |
|
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
arsenic trichloride promotes the reaction [antimony trichloride results in increased cleavage of CASP3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of CASP3 mRNA] |
CTD |
PMID:34091186 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Cat |
catalase |
multiple interactions |
ISO |
CAT protein inhibits the reaction [arsenic trichloride results in increased activity of CTNNB1 protein]; CAT protein inhibits the reaction [arsenic trichloride results in increased expression of CTNNB1 protein] |
CTD |
PMID:21854796 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cdc20 |
cell division cycle 20 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of CDC20 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [HIF1A protein binds to CEBPB gene]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to CEBPB gene]; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of CEBPB mRNA; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of CEBPB protein |
CTD |
PMID:35625704 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cox7a2 |
cytochrome c oxidase subunit 7A2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of COX7A2 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of COX7A2 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633 Ensembl chr 8:51,301,168...51,301,633
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G |
Ctnnb1 |
catenin beta 1 |
increases expression increases activity multiple interactions |
ISO |
arsenic trichloride results in increased expression of CTNNB1 protein arsenic trichloride results in increased activity of CTNNB1 protein CAT protein inhibits the reaction [arsenic trichloride results in increased activity of CTNNB1 protein]; CAT protein inhibits the reaction [arsenic trichloride results in increased expression of CTNNB1 protein] |
CTD |
PMID:21854796 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
ISO |
antimony trichloride promotes the reaction [arsenic trichloride results in increased expression of DDIT3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 protein]; IKBKB affects the reaction [arsenic trichloride results in increased expression of DDIT3 mRNA] |
CTD |
PMID:16283526 PMID:34091186 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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|
G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of DDIT4 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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|
G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of DNAJB1 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Eif3b |
eukaryotic translation initiation factor 3, subunit B |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of EIF3B mRNA |
CTD |
PMID:35809665 |
|
NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
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G |
Eif3i |
eukaryotic translation initiation factor 3, subunit I |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of EIF3I mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
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G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which affects the expression of EIF4G1 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
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G |
Elavl1 |
ELAV like RNA binding protein 1 |
multiple interactions |
ISO |
arsenic trichloride promotes the reaction [ELAVL1 protein binds to GADD45A mRNA] |
CTD |
PMID:16421274 |
|
NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
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G |
Elob |
elongin B |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of ELOB mRNA |
CTD |
PMID:35809665 |
|
NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
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G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of ERN2 mRNA |
CTD |
PMID:35625704 |
|
NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
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G |
Flna |
filamin A |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein]; AKT1 mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein]; arsenic trichloride promotes the reaction [AKT1 protein binds to FLNA protein modified form]; arsenic trichloride promotes the reaction [AKT1 protein modified form binds to FLNA protein modified form]; wortmannin inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein] |
CTD |
PMID:25944616 |
|
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
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G |
Furin |
furin (paired basic amino acid cleaving enzyme) |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of FURIN mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
multiple interactions affects response to substance increases expression |
ISO |
arsenic trichloride promotes the reaction [ELAVL1 protein binds to GADD45A mRNA]; arsenic trichloride promotes the reaction [NCL protein binds to GADD45A mRNA]; arsenic trichloride results in increased stability of and results in increased expression of GADD45A mRNA; GPX1 protein inhibits the reaction [arsenic trichloride results in increased expression of GADD45A protein]; Hydrogen Peroxide promotes the reaction [arsenic trichloride results in increased expression of GADD45A protein] GADD45A protein affects the susceptibility to arsenic trichloride IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45A protein] arsenic trichloride results in increased expression of GADD45A mRNA; arsenic trichloride results in increased expression of GADD45A protein |
CTD |
PMID:16283526 PMID:16421274 PMID:16814109 PMID:18942077 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression multiple interactions |
ISO |
arsenic trichloride results in increased expression of GADD45B mRNA IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45B mRNA] |
CTD |
PMID:16283526 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression multiple interactions |
ISO |
arsenic trichloride results in increased expression of GADD45G mRNA IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45G mRNA] |
CTD |
PMID:16283526 |
|
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
GPX1 protein inhibits the reaction [arsenic trichloride results in increased expression of GADD45A protein] |
CTD |
PMID:16814109 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of GSR mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of GSR mRNA |
CTD |
PMID:35809665 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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|
G |
H2ax |
H2A.X variant histone |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of H2AX protein; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of H2AX protein |
CTD |
PMID:35809665 |
|
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [HIF1A protein binds to CEBPB gene]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [HIF1A protein binds to HSPA1B promoter] |
CTD |
PMID:35625704 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
arsenic trichloride results in increased expression of HMOX1 mRNA [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of HMOX1 mRNA |
CTD |
PMID:19276070 PMID:35809665 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of HSP90B1 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [HIF1A protein binds to HSPA1B promoter]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to HSPA1B gene]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to HSPA1B promoter]; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of HSPA1B protein |
CTD |
PMID:35625704 |
|
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of HSPA5 protein [arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of HSPA5 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of HSPA5 mRNA |
CTD |
PMID:34091186 PMID:35809665 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of HSPH1 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of HSPH1 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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G |
Htra4 |
HtrA serine peptidase 4 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of HTRA4 mRNA |
CTD |
PMID:35625704 |
|
NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
IKBKB affects the reaction [arsenic trichloride results in increased expression of DDIT3 mRNA]; IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45A protein]; IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45B mRNA]; IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45G mRNA] |
CTD |
PMID:16283526 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il2 |
interleukin 2 |
decreases secretion |
ISO |
arsenic trichloride results in decreased secretion of IL2 protein |
CTD |
PMID:27714827 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il6 |
interleukin 6 |
increases secretion |
ISO |
arsenic trichloride results in increased secretion of IL6 protein |
CTD |
PMID:22696236 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Insr |
insulin receptor |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of INSR mRNA |
CTD |
PMID:35809665 |
|
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Mapk10 |
mitogen activated protein kinase 10 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of MAPK10 mRNA |
CTD |
PMID:35625704 |
|
NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein] [arsenic trichloride co-treated with antimony trichloride] results in increased expression of MAPK8 mRNA; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of MAPK8 protein]; MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein]; MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:22696236 PMID:24434654 PMID:34091186 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO |
MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein]; MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] MAPK9 mutant form inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 protein]; pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK9 protein]; stattic inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:22696236 PMID:24434654 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mir106a |
microRNA 106a |
increases expression |
ISO |
arsenic trichloride results in increased expression of MIR106A |
CTD |
PMID:21750348 |
|
NCBI chr X:132,422,584...132,422,661
Ensembl chr X:132,422,584...132,422,661
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G |
Mir17 |
microRNA 17 |
increases expression |
ISO |
arsenic trichloride results in increased expression of MIR17 |
CTD |
PMID:21750348 |
|
NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
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G |
Mir190 |
microRNA 190 |
increases expression multiple interactions |
ISO |
arsenic trichloride results in increased expression of MIR190A [arsenic trichloride results in increased expression of MIR190A] promotes the reaction [[MIR190A binds to PHLPP1 3' UTR] which results in decreased expression of PHLPP1 protein]; [arsenic trichloride results in increased expression of MIR190A] promotes the reaction [[MIR190A binds to TP53INP1 3' UTR] which results in decreased expression of TP53INP1 protein]; [arsenic trichloride results in increased expression of MIR190A] which results in decreased expression of PHLPP1 protein |
CTD |
PMID:21750348 |
|
NCBI chr 8:67,850,987...67,851,071
Ensembl chr 8:67,850,987...67,851,071
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G |
Mir19a |
microRNA 19a |
increases expression |
ISO |
arsenic trichloride results in increased expression of MIR19A |
CTD |
PMID:21750348 |
|
NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
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G |
Mir1b |
microRNA 1b |
increases expression |
ISO |
arsenic trichloride results in increased expression of MIR1-1 |
CTD |
PMID:21750348 |
|
NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201
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G |
Mir20a |
microRNA 20a |
increases expression |
ISO |
arsenic trichloride results in increased expression of MIR20A |
CTD |
PMID:21750348 |
|
NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
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G |
Mir21 |
microRNA 21 |
multiple interactions affects expression |
ISO |
MIR21 mRNA affects the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA]; pyrazolanthrone affects the reaction [arsenic trichloride affects the expression of MIR21 mRNA]; stattic affects the reaction [arsenic trichloride affects the expression of MIR21 mRNA] |
CTD |
PMID:24434654 |
|
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mir92a1 |
microRNA 92a-1 |
increases expression |
ISO |
arsenic trichloride results in increased expression of MIR92A1 |
CTD |
PMID:21750348 |
|
NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413
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|
G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of MKI67 protein; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of MKI67 protein |
CTD |
PMID:35809665 |
|
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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|
G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of COX2 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of COX3 mRNA |
CTD |
PMID:35809665 |
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NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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Mt-nd4l |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ND4L mRNA |
CTD |
PMID:35809665 |
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NCBI chr MT:9,870...10,166 NCBI chr MT:9,870...10,166 NCBI chr MT:9,870...10,166 NCBI chr MT:9,870...10,166 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,870...10,166
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Mt1 |
metallothionein 1 |
increases expression multiple interactions |
ISO |
arsenic trichloride results in increased expression of MT1 mRNA arsenic trichloride promotes the reaction [MTF1 protein binds to MT1 protein]; Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]; MTF1 protein affects the reaction [arsenic trichloride results in increased expression of MT1 mRNA]; MTF1 protein affects the reaction [Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]] |
CTD |
PMID:19276070 |
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NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mtf1 |
metal-regulatory transcription factor 1 |
multiple interactions affects response to substance decreases response to substance |
ISO |
arsenic trichloride promotes the reaction [MTF1 protein binds to MT1 protein]; MTF1 protein affects the reaction [arsenic trichloride results in increased expression of MT1 mRNA]; MTF1 protein affects the reaction [Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]] MTF1 protein affects the susceptibility to arsenic trichloride MTF1 protein results in decreased susceptibility to arsenic trichloride |
CTD |
PMID:19276070 |
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NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
ISO |
arsenic trichloride results in increased expression of MYC mRNA; arsenic trichloride results in increased expression of MYC protein |
CTD |
PMID:16283526 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Ncf1 |
neutrophil cytosolic factor 1 |
increases expression |
ISO |
arsenic trichloride results in increased expression of NCF1 protein |
CTD |
PMID:21854796 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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Ncf2 |
neutrophil cytosolic factor 2 |
increases expression |
ISO |
arsenic trichloride results in increased expression of NCF2 protein |
CTD |
PMID:21854796 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ncl |
nucleolin |
affects localization multiple interactions |
ISO |
arsenic trichloride affects the localization of NCL protein arsenic trichloride promotes the reaction [NCL protein binds to GADD45A mRNA] |
CTD |
PMID:16421274 |
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NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
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Ndufa4 |
Ndufa4, mitochondrial complex associated |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of NDUFA4 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of NDUFA4 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
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Ndufv1 |
NADH:ubiquinone oxidoreductase core subunit V1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of NDUFV1 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466
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Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
NFE2L2 protein affects the reaction [arsenic trichloride results in increased expression of NQO1 mRNA] [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6 promoter]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6B promoter]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to CEBPB gene]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to HSPA1B gene]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to HSPA1B promoter]; [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to UBE2G2 promoter]; NFE2L2 protein affects the reaction [[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ATF6 mRNA]; NFE2L2 protein affects the reaction [[arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of ATF6B mRNA] |
CTD |
PMID:19276070 PMID:35625704 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
arsenic trichloride results in increased expression of NQO1 mRNA NFE2L2 protein affects the reaction [arsenic trichloride results in increased expression of NQO1 mRNA] |
CTD |
PMID:19276070 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Park7 |
Parkinsonism associated deglycase |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PARK7 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of PARK7 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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Phlpp1 |
PH domain and leucine rich repeat protein phosphatase 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased expression of MIR190A] promotes the reaction [[MIR190A binds to PHLPP1 3' UTR] which results in decreased expression of PHLPP1 protein]; [arsenic trichloride results in increased expression of MIR190A] which results in decreased expression of PHLPP1 protein |
CTD |
PMID:21750348 |
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NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
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Ppp2r1a |
protein phosphatase 2 scaffold subunit A alpha |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PPP2R1A mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
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Prdx3 |
peroxiredoxin 3 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PRDX3 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Psma4 |
proteasome 20S subunit alpha 4 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMA4 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
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Psma7 |
proteasome 20S subunit alpha 7 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMA7 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
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Psmb1 |
proteasome 20S subunit beta 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMB1 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
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Psmb2 |
proteasome 20S subunit beta 2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMB2 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
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Psmb4 |
proteasome 20S subunit beta 4 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMB4 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
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Psmb5 |
proteasome 20S subunit beta 5 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMB5 mRNA |
CTD |
PMID:35809665 |
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NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
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Psmb6 |
proteasome 20S subunit beta 6 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMB6 mRNA |
CTD |
PMID:35809665 |
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NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586
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Psmb7 |
proteasome 20S subunit beta 7 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMB7 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
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Psmc2 |
proteasome 26S subunit, ATPase 2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMC2 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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Psmc4 |
proteasome 26S subunit, ATPase 4 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMC4 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
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Psmc5 |
proteasome 26S subunit, ATPase 5 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMC5 mRNA |
CTD |
PMID:35809665 |
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NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
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Psmd1 |
proteasome 26S subunit, non-ATPase 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD1 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
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Psmd11 |
proteasome 26S subunit, non-ATPase 11 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD11 mRNA |
CTD |
PMID:35809665 |
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NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
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Psmd13 |
proteasome 26S subunit, non-ATPase 13 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD13 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
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Psmd14 |
proteasome 26S subunit, non-ATPase 14 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD14 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
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Psmd2 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD2 mRNA |
CTD |
PMID:35809665 |
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NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043
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Psmd4 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 4 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD4 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
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Psmd8 |
proteasome 26S subunit, non-ATPase 8 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMD8 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
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Rb1 |
RB transcriptional corepressor 1 |
increases phosphorylation |
ISO |
arsenic trichloride results in increased phosphorylation of RB1 protein |
CTD |
PMID:16283526 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Riox2 |
ribosomal oxygenase 2 |
multiple interactions increases expression increases phosphorylation |
ISO |
MAPK9 mutant form inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 protein]; MIR21 mRNA affects the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA]; pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA]; pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of RIOX2 protein]; STAT3 mutant form inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 protein]; stattic inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA]; stattic inhibits the reaction [arsenic trichloride results in increased phosphorylation of RIOX2 protein]; wortmannin inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA] arsenic trichloride results in increased expression of RIOX2 mRNA; arsenic trichloride results in increased expression of RIOX2 protein |
CTD |
PMID:24434654 |
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NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574
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Rps12 |
ribosomal protein S12 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS12 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS12 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014
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Rps13 |
ribosomal protein S13 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS13 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 1:170,572,925...170,575,355
Ensembl chr 1:170,572,921...170,575,355 Ensembl chr 3:170,572,921...170,575,355
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Rps15 |
ribosomal protein S15 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS15 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
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Rps18 |
ribosomal protein S18 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS18 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146 Ensembl chr20:101,204,500...101,205,146
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Rps19 |
ribosomal protein S19 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS19 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
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Rps2 |
ribosomal protein S2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS2 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
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Rps20 |
ribosomal protein S20 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS20 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475
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Rps24 |
ribosomal protein S24 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS24 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS24 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279
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Rps25 |
ribosomal protein s25 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS25 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271
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Rps27 |
ribosomal protein S27 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS27 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS27 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964
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Rps27a |
ribosomal protein S27a |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of RPS27A mRNA |
CTD |
PMID:35809665 |
|
NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011 Ensembl chr 5:103,285,734...103,288,011
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G |
Rps4x |
ribosomal protein S4, X-linked |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS4X mRNA |
CTD |
PMID:35809665 |
|
NCBI chr X:67,298,522...67,302,965
Ensembl chr X:67,298,525...67,303,019 Ensembl chr 4:67,298,525...67,303,019
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G |
Rps5 |
ribosomal protein S5 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS5 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 1:73,538,776...73,543,073
Ensembl chr 1:73,538,776...73,543,073
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G |
Rps7 |
ribosomal protein S7 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS7 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
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G |
Rps9 |
ribosomal protein S9 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS9 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr 1:65,511,723...65,515,076
Ensembl chr 1:65,511,723...65,515,123
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G |
Scap |
SREBF chaperone |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of SCAP mRNA |
CTD |
PMID:35625704 |
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NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
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G |
Stat3 |
signal transducer and activator of transcription 3 |
increases phosphorylation multiple interactions affects phosphorylation |
ISO |
arsenic trichloride results in increased phosphorylation of STAT3 protein pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]; STAT3 mutant form inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 protein]; STAT3 mutant form inhibits the reaction [arsenic trichloride results in increased expression of VEGFA protein] MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]; MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] arsenic trichloride affects the phosphorylation of STAT3 protein |
CTD |
PMID:22696236 PMID:24434654 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Tln2 |
talin 2 |
increases expression |
ISO |
arsenic trichloride results in increased expression of TLN2 mRNA; arsenic trichloride results in increased expression of TLN2 protein |
CTD |
PMID:21750348 |
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NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219
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G |
Tp53 |
tumor protein p53 |
increases phosphorylation multiple interactions |
ISO |
arsenic trichloride results in increased phosphorylation of TRP53 protein arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 protein] |
CTD |
PMID:16283526 PMID:34091186 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tp53inp1 |
tumor protein p53 inducible nuclear protein 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased expression of MIR190A] promotes the reaction [[MIR190A binds to TP53INP1 3' UTR] which results in decreased expression of TP53INP1 protein] |
CTD |
PMID:21750348 |
|
NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
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G |
Uba52 |
ubiquitin A-52 residue ribosomal protein fusion product 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of UBA52 mRNA |
CTD |
PMID:35809665 |
|
NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
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G |
Ubc |
ubiquitin C |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of UBC mRNA |
CTD |
PMID:35809665 |
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NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
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G |
Ube2g2 |
ubiquitin-conjugating enzyme E2G 2 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to UBE2G2 promoter]; [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of UBE2G2 protein |
CTD |
PMID:35625704 |
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NCBI chr20:10,983,734...11,005,468
Ensembl chr20:10,983,742...11,005,447
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
multiple interactions |
ISO |
[Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in increased expression of UCHL1 mRNA |
CTD |
PMID:35809665 |
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NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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G |
Uqcrc1 |
ubiquinol-cytochrome c reductase core protein 1 |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of UQCRC1 mRNA |
CTD |
PMID:35809665 |
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NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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G |
Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
multiple interactions |
ISO |
[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of UQCRH mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of UQCRH mRNA |
CTD |
PMID:35809665 |
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NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression |
ISO |
STAT3 mutant form inhibits the reaction [arsenic trichloride results in increased expression of VEGFA protein] |
CTD |
PMID:22696236 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of XBP1 mRNA; arsenic trichloride inhibits the reaction [antimony trichloride results in increased expression of XBP1 protein] |
CTD |
PMID:34091186 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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