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ONTOLOGY REPORT - ANNOTATIONS


Term:genotoxin
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Accession:CHEBI:50902 term browser browse the term
Definition:A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
Synonyms:related_synonym: genotoxic agent;   genotoxic agents;   genotoxins
 xref: Wikipedia:Genotoxicity


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  CHEBI ontology 19669
    role 19613
      biological role 19611
        aetiopathogenetic role 18766
          genotoxin 16034
            1,5-dinitronaphthalene 0
            1-naphthol + 164
            2,6-dinitrotoluene 2201
            2-naphthol + 37
            4-methoxyestrone + 0
            7-epi-cylindrospermopsin 0
            MeIQx + 164
            N-(2,6-diethylphenyl)-2-chloroacetamide 0
            N-ethyl-N-nitrosourea 508
            N-hydroxy-MeIQx 0
            N-hydroxy-PhIP 23
            acridine + 26
            arsenic trichloride 40
            benzamidoxime 6
            benzo[a]pyrene-7,8-dione 18
            beryllium dichloride 3
            cadmium nitrate + 3
            cadmium nitrate tetrahydrate 0
            camptothecin 192
            catechol + 294
            cisplatin 7278
            cobalt(2+) sulfate heptahydrate 0
            cylindrospermopsin 514
            ebselen 53
            ethoxyquin 43
            ethyl methanesulfonate 2173
            hydrogen peroxide + 3025
            hydrogen sulfide + 1982
            hydroxyurea 213
            imidacloprid + 76
            methyl methanesulfonate 3643
            mutagen + 15652
            o-anisidine 94
            p-anisidine + 39
            parathion-methyl 50
            riddelliine + 64
            riddelliine N-oxide 0
            tolylfluanid 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.