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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of steroid biosynthetic process
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Accession:GO:0050810 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms:exact_synonym: regulation of steroid anabolism;   regulation of steroid biosynthesis;   regulation of steroid formation;   regulation of steroid synthesis;   regulation of steroidogenesis


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regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 IDA RGD PMID:4392955 RGD:2303525 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Armc5 armadillo repeat containing 5 acts_upstream_of_or_within ISO MGI:6157645 (PMID:28911199) RGD PMID:28911199 NCBI chr 1:192,250,580...192,257,347
Ensembl chr 1:182,820,141...182,826,907 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22927646)
(PMID:22261821)		 UniProt
RGD		 PMID:22261821 PMID:22927646 GO_REF:0000024 NCBI chr16:57,669,927...57,701,349
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Ddx20 DEAD-box helicase 20 acts_upstream_of_or_within ISO MGI:3795148 (PMID:18258677) RGD PMID:18258677 NCBI chr 2:195,847,105...195,859,989
Ensembl chr 2:193,158,823...193,166,774 		JBrowse link
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1095403 (PMID:17495005) RGD PMID:17495005 NCBI chr 7:131,929,857...131,935,352
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IDA RGD PMID:4392955 RGD:2303525 NCBI chr 2:186,008,944...186,028,417
Ensembl chr 2:186,008,943...186,020,393 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 IMP RGD PMID:17522074 RGD:1626541 NCBI chr14:31,091,681...31,151,623
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:1856424 (PMID:16513828) RGD PMID:16513828 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IEP RGD PMID:17241129 RGD:1600071 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 TAS RGD PMID:15358680 RGD:1357210 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO MGI:94891 (PMID:17495005) RGD PMID:17495005 NCBI chr 1:213,090,256...213,112,688
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Star steroidogenic acute regulatory protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:7961770)		 GO_Central
RGD		 PMID:7961770 GO_REF:0000033 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tspo translocator protein IMP RGD PMID:9974124 RGD:2317173 NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19584291)		 Ensembl
RGD		 PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP		 (PMID:19342457)
GO_REF:0000107		 RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:16959810)
GO_REF:0000107		 RGD
Ensembl		 PMID:16959810 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 ISO (PMID:12815072)
MGI:1928271 (PMID:23747249)		 RGD PMID:12815072 PMID:23747249 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO MGI:1096383|MGI:2154956 (PMID:23747249) RGD PMID:23747249 NCBI chr17:83,327,372...84,039,558
Ensembl chr17:78,418,819...79,131,016 		JBrowse link
G Mir33 microRNA 33 involved_in ISO (PMID:23536474) RGD PMID:23536474 NCBI chr 7:115,593,952...115,594,020
Ensembl chr 7:113,713,855...113,713,923 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:16488887) RGD PMID:16488887 NCBI chr13:104,196,615...104,251,007
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO (PMID:16549446) RGD PMID:16549446 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) RGD PMID:15243130 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:1917954)		 Ensembl
RGD		 PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Chlsn cholesin involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,298,968...20,402,890
Ensembl chr12:15,185,707...15,289,069 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:66,022,731...66,026,333
Ensembl chr17:61,331,669...61,334,285 		JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 (PMID:19584291)
GO_REF:0000107		 RGD
Ensembl		 PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP		 (PMID:19342457)
GO_REF:0000107		 RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2451290 (PMID:17234593)		 Ensembl
RGD		 PMID:17234593 GO_REF:0000107 NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Hrh1 histamine receptor H 1 IMP RGD PMID:15917347 RGD:2316921 NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (PMID:16100574) RGD PMID:16100574 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1916289 (PMID:16100574)		 Ensembl
RGD		 PMID:16100574 GO_REF:0000107 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 acts_upstream_of
involved_in		 ISO
ISS
IEA		 (PMID:9384387)
GO_REF:0000024
GO_REF:0000107		 RGD
HGNC-UCL
Ensembl		 PMID:9384387 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:15317892), (PMID:18182450) RGD PMID:15317892 PMID:18182450 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within ISO MGI:5526098 (PMID:21187369) RGD PMID:21187369 NCBI chr 2:28,009,841...28,244,050
Ensembl chr 2:26,276,635...26,509,209 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) RGD PMID:18818293 NCBI chr 1:104,830,462...104,835,711
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in ISO (PMID:25264202) RGD PMID:25264202 NCBI chr 4:106,027,918...106,043,653
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:12949260)
GO_REF:0000107		 RGD
Ensembl		 PMID:12949260 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) RGD PMID:19502595 NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) RGD PMID:16527843 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:16981135)
GO_REF:0000107		 RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:18565334), (PMID:19721697)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18565334 PMID:19721697 GO_REF:0000024 GO_REF:0000107 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Star steroidogenic acute regulatory protein involved_in ISO (PMID:18403318) RGD PMID:18403318 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) RGD PMID:18403318 NCBI chr18:25,088,831...25,104,172
Ensembl chr18:24,817,107...24,830,024 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17916878) RGD PMID:17916878 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17916878)		 Ensembl
RGD		 PMID:17916878 GO_REF:0000107 NCBI chr 8:53,508,005...53,525,314
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19229075)		 UniProt
RGD		 PMID:19229075 GO_REF:0000024 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Gnai1 G protein subunit alpha i1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in ISO (PMID:11163209) RGD PMID:11163209 NCBI chr  X:41,225,956...41,290,030
Ensembl chr  X:37,410,811...37,464,430 		JBrowse link
G Mir182 microRNA 182 involved_in ISO RNAcentral:URS000016FF9C_9606 (PMID:23823476) RGD PMID:23823476 NCBI chr 4:59,752,246...59,752,307
Ensembl chr 4:58,784,818...58,784,879 		JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of		 ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077)		 RGD PMID:23823476 PMID:30460077 NCBI chr 4:59,755,841...59,755,946
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:32976883 RGD:405096663 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr14:12,766,539...12,796,461
Ensembl chr14:12,462,563...12,479,994 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:38503280)		 Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) RGD PMID:33942715 NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:110,306,031...110,360,666 		JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:12177166)
(PMID:8833906), (PMID:9062341)
MGI:2177958|MGI:2177959 (PMID:16046411), (PMID:9329978)
GO_REF:0000024
(PMID:32322062)		 RGD
UniProt		 PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... GO_REF:0000024 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:33942715), (PMID:34021134)
(PMID:12177166), (PMID:38503280)
GO_REF:0000024
(PMID:32322062)		 Ensembl
RGD
UniProt		 PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 PMID:38503280 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO
IEA		 (PMID:16981135)
GO_REF:0000107		 RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
positive regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16923850), (PMID:17670946)		 UniProt
RGD		 PMID:16923850 PMID:17670946 GO_REF:0000024 NCBI chr13:50,865,253...50,985,107
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:20133449 RGD:10059648 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
positive regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IMP RGD PMID:18582595 RGD:2316120 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide involved_in ISO
IBA
ISS		 (PMID:2494176)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:2494176 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Fshb follicle stimulating hormone subunit beta involved_in ISO (PMID:2494176) RGD PMID:2494176 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:16595703 RGD:2311095 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in IMP
IDA		 PMID:1703300 RGD
UniProt		 PMID:3030719 PMID:1703300 RGD:9999179, RGD:8554045 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IMP androstenedione RGD PMID:19615041 RGD:4888510 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Gh1 growth hormone 1 involved_in IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in IMP PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 involved_in IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Por cytochrome p450 oxidoreductase IDA hydroxylation RGD PMID:2495435 RGD:4889602 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:9282826) RGD PMID:9282826 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:1690216) RGD PMID:1690216 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO
ISS		 (PMID:29403011)
GO_REF:0000024		 RGD
UniProt		 PMID:29403011 GO_REF:0000024 NCBI chr11:93,702,382...93,716,059
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D involved_in ISO (PMID:18599737) RGD PMID:18599737 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO
IDA		 (PMID:19965590)
PMID:1694852		 RGD PMID:19965590 PMID:1694852 RGD:70534 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISO
IBA
IEA
ISS		 (PMID:17623664), (PMID:20683963)
(PMID:10809780)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:10809780 PMID:17623664 PMID:20683963 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20375098)		 Ensembl
RGD		 PMID:20375098 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:28,642,660...28,662,689
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Apob apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2183298 (PMID:16455790)		 Ensembl
RGD		 PMID:16455790 GO_REF:0000107 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Aqp8 aquaporin 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:30579780)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:30579780 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Gpr146 G protein-coupled receptor 146 involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,365,790...20,381,122
Ensembl chr12:15,251,813...15,267,206 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29395055)		 UniProt
RGD		 PMID:29395055 GO_REF:0000024 NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:42,141,384...42,158,882 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (PMID:14673138) RGD PMID:14673138 NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:96,045,958...96,073,404 		JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2148743|MGI:2180899 (PMID:16054043)		 GO_Central
RGD		 PMID:16054043 GO_REF:0000033 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:110,306,031...110,360,666 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,203,380...1,217,536
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO (PMID:18628520), (PMID:23132696)
(PMID:16356929)		 RGD PMID:16356929 PMID:18628520 PMID:23132696 NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857745 (PMID:7628695)		 Ensembl
RGD		 PMID:7628695 GO_REF:0000107 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,203,380...1,217,536
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Egr1 early growth response 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8703054)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8703054 GO_REF:0000024 GO_REF:0000107 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:23045399 RGD:26884342 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir455 microRNA 455 IDA RGD PMID:23045399 RGD:26884342 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181999 (PMID:11145748)		 Ensembl
RGD		 PMID:11145748 GO_REF:0000107 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:19336506) RGD PMID:19336506 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:21333348)		 UniProt
RGD		 PMID:21333348 GO_REF:0000024 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 involved_in ISO (PMID:21333348) RGD PMID:21333348 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A involved_in ISS
ISO		 GO_REF:0000024
(PMID:21333348)		 UniProt
RGD		 PMID:21333348 GO_REF:0000024 NCBI chr20:31,464,818...31,486,121
Ensembl chr20:30,922,106...30,943,412 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:22429315 RGD:7775068 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      regulation of cellular process 13023
        regulation of metabolic process 6832
          regulation of biosynthetic process 5630
            regulation of lipid biosynthetic process 233
              regulation of steroid biosynthetic process 103
                negative regulation of steroid biosynthetic process + 30
                positive regulation of steroid biosynthetic process + 39
                regulation of androst-4-ene-3,17-dione biosynthetic process + 0
                regulation of bile acid biosynthetic process + 11
                regulation of estrogen biosynthetic process + 1
                regulation of helvolic acid biosynthetic process + 0
                regulation of progesterone biosynthetic process + 6
                regulation of steroid hormone biosynthetic process + 21
                regulation of sterol biosynthetic process + 37
                regulation of testosterone biosynthetic process + 8
                regulation of vitamin D biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        regulation of cellular process 13023
          regulation of metabolic process 6832
            regulation of primary metabolic process 5683
              regulation of lipid metabolic process 391
                regulation of steroid metabolic process 129
                  regulation of steroid biosynthetic process 103
                    negative regulation of steroid biosynthetic process + 30
                    positive regulation of steroid biosynthetic process + 39
                    regulation of androst-4-ene-3,17-dione biosynthetic process + 0
                    regulation of bile acid biosynthetic process + 11
                    regulation of estrogen biosynthetic process + 1
                    regulation of helvolic acid biosynthetic process + 0
                    regulation of progesterone biosynthetic process + 6
                    regulation of steroid hormone biosynthetic process + 21
                    regulation of sterol biosynthetic process + 37
                    regulation of testosterone biosynthetic process + 8
                    regulation of vitamin D biosynthetic process + 7
paths to the root