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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of steroid hormone biosynthetic process
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Accession:GO:0090030 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.



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regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhcgr luteinizing hormone/choriogonadotropin receptor acts_upstream_of_or_within ISO
IEA
MGI:2181999 (PMID:11145748)
GO_REF:0000107
RGD
Ensembl
PMID:11145748 GO_REF:0000107 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:11,415,415...11,478,061
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19584291)
Ensembl
RGD
PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:85,396,925...85,520,189
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:175,672,834...175,715,186
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:31,213,415...31,248,662
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA
(PMID:19584291)
GO_REF:0000107
RGD
Ensembl
PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:85,396,925...85,520,189
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:175,672,834...175,715,186
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IMP
IEA
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:31,213,415...31,248,662
JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO
IEA
MGI:2451290 (PMID:17234593)
GO_REF:0000107
RGD
Ensembl
PMID:17234593 GO_REF:0000107 NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within ISO
IEA
MGI:5526098 (PMID:21187369)
GO_REF:0000107
RGD
Ensembl
PMID:21187369 GO_REF:0000107 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:28,011,359...28,244,327
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO
IEA
(PMID:16527843)
GO_REF:0000107
RGD
Ensembl
PMID:16527843 GO_REF:0000107 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,523,704...26,675,261
JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:57,242,064...57,294,888
JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA
(PMID:16981135)
GO_REF:0000107
RGD
Ensembl
PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128
JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO
IEA
(PMID:16981135)
GO_REF:0000107
RGD
Ensembl
PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128
JBrowse link
positive regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16923850), (PMID:17670946)
UniProt
Ensembl
RGD
PMID:16923850 PMID:17670946 GO_REF:0000024 GO_REF:0000107 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:50,867,920...50,984,938
JBrowse link
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IMP androstenedione RGD PMID:19615041 RGD:4888510 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
JBrowse link
G Gh1 growth hormone 1 involved_in IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in IMP PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
JBrowse link
G Igf2 insulin-like growth factor 2 involved_in IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
JBrowse link
G Por cytochrome p450 oxidoreductase IDA hydroxylation RGD PMID:2495435 RGD:4889602 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO
IEA
ISS
(PMID:29403011)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:29403011 GO_REF:0000024 GO_REF:0000107 NCBI chr11:93,702,382...93,716,059
Ensembl chr11:93,702,360...93,716,059
JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,203,380...1,217,536
Ensembl chr14:1,203,565...1,218,024
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO
IEA
(PMID:18628520), (PMID:23132696)
GO_REF:0000107
(PMID:16356929)
RGD
Ensembl
PMID:16356929 PMID:18628520 PMID:23132696 GO_REF:0000107 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:165,721,654...165,753,125
JBrowse link
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 acts_upstream_of_or_within ISO
IEA
MGI:1857745 (PMID:7628695)
GO_REF:0000107
RGD
Ensembl
PMID:7628695 GO_REF:0000107 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      metabolic process 12252
        hormone metabolic process 269
          regulation of hormone metabolic process 50
            regulation of hormone biosynthetic process 31
              regulation of steroid hormone biosynthetic process 21
                negative regulation of steroid hormone biosynthetic process + 6
                positive regulation of steroid hormone biosynthetic process + 10
                regulation of aldosterone biosynthetic process + 8
                regulation of brassinosteroid biosynthetic process + 0
                regulation of ecdysteroid biosynthetic process + 0
                regulation of glucocorticoid biosynthetic process + 10
Path 2
Term Annotations click to browse term
  biological_process 20668
    biological regulation 13899
      regulation of biological process 13475
        regulation of cellular process 13055
          regulation of metabolic process 6832
            regulation of primary metabolic process 5664
              regulation of lipid metabolic process 408
                regulation of lipid biosynthetic process 245
                  regulation of steroid biosynthetic process 108
                    regulation of steroid hormone biosynthetic process 21
                      negative regulation of steroid hormone biosynthetic process + 6
                      positive regulation of steroid hormone biosynthetic process + 10
                      regulation of aldosterone biosynthetic process + 8
                      regulation of brassinosteroid biosynthetic process + 0
                      regulation of ecdysteroid biosynthetic process + 0
                      regulation of glucocorticoid biosynthetic process + 10
paths to the root