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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of vitamin D biosynthetic process
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Accession:GO:0010957 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).



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negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) RGD PMID:19502595 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA
(PMID:16549446)
GO_REF:0000107
RGD
Ensembl
PMID:16549446 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) RGD PMID:15243130 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      biosynthetic process 6264
        negative regulation of biosynthetic process 1773
          negative regulation of cellular biosynthetic process 1703
            negative regulation of vitamin D biosynthetic process 5
              negative regulation of calcidiol 1-monooxygenase activity 3
Path 2
Term Annotations click to browse term
  biological_process 19746
    biological regulation 13447
      regulation of biological process 13040
        regulation of metabolic process 6832
          regulation of primary metabolic process 5852
            regulation of lipid metabolic process 406
              regulation of steroid metabolic process 115
                negative regulation of steroid metabolic process 32
                  negative regulation of steroid biosynthetic process 30
                    negative regulation of vitamin D biosynthetic process 5
                      negative regulation of calcidiol 1-monooxygenase activity 3
paths to the root