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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol biosynthetic process
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Accession:GO:0045542 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: positive regulation of cholesterol anabolism;   positive regulation of cholesterol biosynthesis;   positive regulation of cholesterol formation;   positive regulation of cholesterol synthesis;   up regulation of cholesterol biosynthetic process;   upregulation of cholesterol biosynthetic process
 narrow_synonym: activation of cholesterol biosynthetic process;   stimulation of cholesterol biosynthetic process


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positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) RGD PMID:17916878 MGI:3768186 NCBI chr20:9,126,687...9,182,948 JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676 JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:174,497,402...174,507,031 JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19229075)
UniProt
RGD
PMID:19229075 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667 JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198 JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:110,306,031...110,360,677 JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:122,806,949...122,881,259 JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:78,973,805...78,998,480 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:32322062)
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
MGI:2177958|MGI:2177959 (MGI:1098057|PMID:9329978), (MGI:3603730|PMID:16046411)
GO_REF:0000024
RGD
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:16046411 PMID:32322062 GO_REF:0000024 MGI:1098057 MGI:3603730 MGI:3623165 MGI:83216 NCBI chr10:45,007,637...45,029,650 JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:32322062)
UniProt
RGD
PMID:32322062 GO_REF:0000024 NCBI chr 7:113,663,202...113,720,850 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      positive regulation of metabolic process 3868
        positive regulation of small molecule metabolic process 162
          positive regulation of cholesterol metabolic process 11
            positive regulation of cholesterol biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of primary metabolic process 5755
            regulation of lipid metabolic process 375
              regulation of steroid metabolic process 114
                regulation of steroid biosynthetic process 82
                  regulation of sterol biosynthetic process 22
                    regulation of cholesterol biosynthetic process 22
                      positive regulation of cholesterol biosynthetic process 10
paths to the root