Bcl2 (BCL2, apoptosis regulator) - Rat Genome Database

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Gene: Bcl2 (BCL2, apoptosis regulator) Rattus norvegicus
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Symbol: Bcl2
Name: BCL2, apoptosis regulator
RGD ID: 2199
Description: Enables BH domain binding activity. Involved in several processes, including central nervous system development; regulation of apoptotic process; and response to monosaccharide. Located in mitochondrial crista and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple); end stage renal disease; gastric ulcer; intestinal disease (multiple); and status epilepticus. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); carcinoma (multiple); intrinsic cardiomyopathy (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator); PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; erythropoietin signaling pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-sesamin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: apoptosis regulator Bcl-2; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl-2; Bcl-2alpha; Bcl2-like protein; ENSRNOG00000067693
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Iddm12
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81323,204,464 - 23,366,900 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1323,204,464 - 23,366,900 (-)EnsemblGRCr8
mRatBN7.21322,689,783 - 22,853,920 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1323,013,354 - 23,175,038 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,297,817 - 24,459,509 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01322,983,528 - 23,145,223 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,605,426 - 26,769,374 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,605,426 - 26,769,374 (-)Ensemblrn6Rnor6.0
Rnor_5.01331,758,213 - 31,920,775 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41312,730,736 - 12,905,108 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1322,550,362 - 22,711,143 (-)NCBICelera
RGSC_v3.11312,730,735 - 12,905,108 (-)NCBI
Cytogenetic Map13p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
abdominal obesity-metabolic syndrome 1  (IEP)
acute kidney failure  (IEP)
Acute Lung Injury  (IEP)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoma  (ISO)
Adrenal Insufficiency  (IEP)
AIDS-Related Kaposi Sarcoma  (ISO)
alcoholic liver cirrhosis  (ISO)
allergic contact dermatitis  (ISO)
allergic rhinitis  (IEP)
Alzheimer's disease  (IDA,IEP,ISO)
amyotrophic lateral sclerosis  (ISO)
anti-basement membrane glomerulonephritis  (IEP)
asthma  (ISO)
atherosclerosis  (IEP)
autistic disorder  (ISO)
azoospermia  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bilirubin metabolic disorder  (IEP)
brain glioma  (IDA,IEP)
Brain Hypoxia-Ischemia  (IEP)
Brain Injuries  (IEP,IMP)
brain ischemia  (IDA)
Breast Neoplasms  (ISO)
Burns  (IEP)
carcinoma  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chronic Intermittent Hypoxia  (IDA)
clear cell adenocarcinoma  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (IDA)
Colonic Neoplasms  (IEP,ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (IEP)
contact dermatitis  (ISO)
dementia  (IEP)
Diabetic Cardiomyopathies  (IDA,ISO)
diffuse large B-cell lymphoma  (ISO)
dilated cardiomyopathy  (IEP)
Disease Progression  (ISO)
ductal carcinoma in situ  (ISO)
end stage renal disease  (IDA)
Endometrial Neoplasms  (ISO)
endometriosis  (IDA,ISO)
Endotoxemia  (IEP)
Esophageal Neoplasms  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Allergic Asthma  (IEP)
Experimental Arthritis  (IEP)
Experimental Colitis  (IEP)
Experimental Diabetes Mellitus  (IEP,ISO)
Experimental Liver Cirrhosis  (IDA,IEP)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (IDA)
Familial Prostate Cancer  (ISO)
Fetal Growth Retardation  (IEP)
follicular lymphoma  (ISO)
Gallbladder Neoplasms  (ISO)
gastric ulcer  (IDA)
glaucoma  (IEP)
Head and Neck Neoplasms  (ISO)
Hemorrhagic Shock  (IEP)
hepatocellular carcinoma  (IEP,ISO)
Huntington's disease  (IEP)
hypertension  (IEP,ISO)
hypertrophic cardiomyopathy  (IEP,ISO)
Hypothermia  (IEP)
impotence  (IDA,IEP,ISO)
intestinal disease  (IDA)
Intestinal Neoplasms  (ISO)
intracranial aneurysm  (ISO)
Kashin-Beck Disease  (ISO)
Kidney Reperfusion Injury  (IEP)
Knee Osteoarthritis  (IEP)
learning disability  (ISO)
leiomyoma  (IEP,ISO)
Liver Reperfusion Injury  (IDA,IEP,ISO)
Lung Injury  (IEP)
Lung Reperfusion Injury  (IEP)
lung small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
male infertility  (ISO)
malignant mesothelioma  (ISO)
melanoma  (ISO)
Memory Disorders  (ISO)
mesenchymal chondrosarcoma  (ISO)
Metaplasia  (ISO)
middle cerebral artery infarction  (IEP)
morphine dependence  (IEP)
Multi-Infarct Dementia  (IEP)
multiple myeloma  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (IEP)
Myocardial Reperfusion Injury  (IDA,IEP)
nasopharynx carcinoma  (ISO)
Necrosis  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
Nerve Degeneration  (ISO)
non-Hodgkin lymphoma  (ISO)
obesity  (IEP)
oligomeganephronia  (ISS)
Optic Nerve Injuries  (IEP)
oral mucosa leukoplakia  (IEP)
osteoarthritis  (ISO)
osteochondrodysplasia  (ISO)
osteoporosis  (IEP)
Ovarian Neoplasms  (ISO)
Oxygen-Induced Retinopathy  (ISO)
plasmacytoma  (ISO)
polycystic ovary syndrome  (IEP,ISO)
post-traumatic stress disorder  (IEP)
Postoperative Cognitive Dysfunction  (IEP)
Premature Aging  (ISO)
priapism  (IEP)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (IEP)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Retina Reperfusion Injury  (IDA)
retinal degeneration  (IEP,ISO)
Sarcopenia  (IEP)
Soft Tissue Neoplasms  (ISO)
Spinal Cord Injuries  (IEP)
squamous cell carcinoma  (IEP)
status epilepticus  (IDA,IEP)
stomach cancer  (ISO)
Subarachnoid Hemorrhage  (IEP)
synovial sarcoma  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
Testis Reperfusion Injury  (IEP)
Tongue Neoplasms  (IEP)
tongue squamous cell carcinoma  (ISO)
transient cerebral ischemia  (IDA,IEP)
transitional cell carcinoma  (ISO)
Transplant Rejection  (IEP)
type 2 diabetes mellitus  (IEP,ISO)
urinary bladder cancer  (ISO)
Ventricular Remodeling  (ISO)
Viral Bronchiolitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP,ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-pilocarpine  (EXP)
(+)-sesamin  (EXP,ISO)
(+)-taxifolin  (EXP)
(+)-Tetrandrine  (ISO)
(-)-alpha-phellandrene  (ISO)
(-)-anisomycin  (EXP)
(-)-citrinin  (ISO)
(-)-ephedrine  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-gambogic acid  (ISO)
(-)-noscapine  (ISO)
(-)-selegiline  (ISO)
(20S)-ginsenoside Rg3  (ISO)
(20S)-ginsenoside Rh2  (ISO)
(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one  (ISO)
(E)-roxithromycin  (ISO)
(E)-thiamethoxam  (ISO)
(E,E)-germacrone  (ISO)
(R)-adrenaline  (ISO)
(R)-carnitine  (EXP)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (EXP)
(R)-salsolinol  (EXP)
(R,R)-tramadol  (EXP)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(R,S)-Scoulerine  (ISO)
(S)-(-)-perillyl alcohol  (ISO)
(S)-amphetamine  (ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (EXP,ISO)
(S)-nicotine  (EXP,ISO)
(S)-ropivacaine  (EXP,ISO)
(Z)-ligustilide  (ISO)
1'-acetoxychavicol acetate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,3-dichloropropan-2-ol  (ISO)
1,3-dinitrobenzene  (EXP,ISO)
1,3-thiazolidine-2,4-dione  (ISO)
1,4-benzoquinone  (ISO)
1,4-dithiothreitol  (ISO)
1,4-naphthoquinone  (ISO)
1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
10-Hydroxycamptothecin  (ISO)
11-deoxycorticosterone  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
1H-pyrazole  (ISO)
2''-galloylhyperin  (ISO)
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,5-hexanedione  (EXP,ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-acetamidofluorene  (EXP)
2-acetamidophenol  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-aminoethoxydiphenylborane  (EXP)
2-chloroethanol  (EXP)
2-deoxy-D-glucose  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (EXP,ISO)
2-methyl-6-(phenylethynyl)pyridine  (EXP,ISO)
2-tert-butylhydroquinone  (EXP,ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
20-hydroxyecdysone  (ISO)
20-hydroxypregn-4-en-3-one  (ISO)
25-hydroxycholesterol  (ISO)
3',4'-dimethoxyflavone  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5'-triiodo-L-thyronine  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-Dichlorobenzidine  (ISO)
3,3'-diindolylmethane  (ISO)
3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine  (ISO)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (EXP,ISO)
3-methylcholanthrene  (EXP,ISO)
3-methylthiopropanal  (ISO)
3-nitropropanoic acid  (EXP,ISO)
3-phenylprop-2-enal  (EXP,ISO)
4'-epidoxorubicin  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-amino-1,8-naphthalimide  (ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (ISO)
4-methylthioamphetamine  (ISO)
4-nitroaniline  (ISO)
4-nitrophenol  (ISO)
4-nonylphenol  (EXP,ISO)
4-octylphenol  (ISO)
4-phenylbutyric acid  (EXP,ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aminolevulinic acid  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
5-fluorouracil  (EXP,ISO)
5-Geranyloxy-7-methoxycoumarin  (ISO)
5-Hydroxycapric acid  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
5alpha-pregnane-3,20-dione  (ISO)
6-anilino-5,8-quinolinedione  (ISO)
6-bromoindirubin-3'-oxime  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP,ISO)
6-oxocampestanol  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP)
7,12-dimethyltetraphene  (EXP,ISO)
7,8-dihydroxycoumarin  (ISO)
7-ketocholesterol  (EXP)
8-Br-cAMP  (ISO)
8-OH-DPAT  (ISO)
9,10-anthraquinone  (ISO)
9,10-phenanthroquinone  (ISO)
9,11,13-octadecatrienoic acid  (ISO)
9-cis-retinoic acid  (ISO)
9-Methoxycamptothecin  (ISO)
[6]-Shogaol  (ISO)
abamectin  (EXP)
Abemaciclib  (ISO)
ABT-737  (ISO)
acadesine  (EXP,ISO)
acetaldehyde  (ISO)
acetamide  (EXP)
acetamiprid  (EXP,ISO)
acetic acid  (EXP)
acetylsalicylic acid  (EXP,ISO)
acifluorfen  (ISO)
aconitine  (EXP)
acrolein  (EXP,ISO)
acrylamide  (EXP,ISO)
acrylonitrile  (ISO)
actinomycin D  (ISO)
Adenosine, cyclic 3',5'-[hydrogen [p(s)]-phosphorothioate]  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
afzelechin  (EXP)
agomelatine  (EXP)
AH23848  (ISO)
alachlor  (ISO)
alantolactone  (ISO)
alborixin  (ISO)
albuterol  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldicarb  (EXP)
alendronic acid  (ISO)
alginic acid  (ISO)
all-trans-acitretin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
allethrin  (EXP,ISO)
allicin  (ISO)
allopurinol  (EXP)
alloxan  (EXP)
Allyl chloride  (EXP)
Aloe emodin  (ISO)
Aloperine  (EXP)
alpha-amanitin  (ISO)
alpha-D-galactose  (EXP,ISO)
alpha-mangostin  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (ISO)
Alpinetin  (ISO)
alpinumisoflavone  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
alvocidib  (ISO)
AM-251  (ISO)
ambrisentan  (ISO)
amentoflavone  (ISO)
amidotrizoic acid  (ISO)
amifostine  (ISO)
amino acid  (ISO)
aminoguanidine  (ISO)
aminophylline  (ISO)
amiodarone  (EXP,ISO)
amitraz  (ISO)
amitriptyline  (EXP)
amitrole  (EXP)
amlexanox  (ISO)
amlodipine  (EXP,ISO)
ammonium chloride  (EXP)
Ammothamnine  (ISO)
amodiaquine  (ISO)
amphetamine  (EXP,ISO)
amsacrine  (ISO)
andrographolide  (ISO)
Anemoside B4  (ISO)
anethole  (EXP)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimony(0)  (EXP,ISO)
antimycin A  (ISO)
Antrocin  (ISO)
apigenin  (EXP,ISO)
apocynin  (EXP,ISO)
aprepitant  (ISO)
arachidonic acid  (ISO)
arachidonyl-2'-chloroethylamide  (ISO)
arecoline  (EXP,ISO)
aristolochic acid A  (EXP,ISO)
arjunolic acid  (EXP,ISO)
Aroclor 1254  (EXP,ISO)
arotinoid acid  (ISO)
arsane  (EXP,ISO)
arsenic acid  (ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
Arsenobetaine  (ISO)
arsenous acid  (EXP,ISO)
artesunate  (EXP,ISO)
asarone  (ISO)
asbestos  (ISO)
asiatic acid  (EXP,ISO)
aspartame  (EXP,ISO)
Aspidin  (ISO)
astaxanthin  (EXP)
astemizole  (EXP)
astilbin  (ISO)
astragaloside IV  (ISO)
atorvastatin calcium  (EXP,ISO)
ATP  (ISO)
Atractylenolide III  (ISO)
Atranorin  (ISO)
atrasentan  (EXP)
atrazine  (EXP,ISO)
auranofin  (ISO)
aurantio-obtusin  (ISO)
aureusidin  (ISO)
Auriculasin  (ISO)
avermectin  (ISO)
azadirachtin A  (ISO)
azide  (ISO)
aziridines  (ISO)
Azoxymethane  (EXP,ISO)
bafilomycin A1  (EXP,ISO)
baicalein  (ISO)
baicalin  (EXP,ISO)
bathocuproine disulfonic acid  (ISO)
Bavachinin  (ISO)
Bay-K-8644  (ISO)
beauvericin  (ISO)
belinostat  (ISO)
benazepril  (EXP)
benomyl  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzoates  (ISO)
benzoic acid  (ISO)
benzophenanthridine  (ISO)
benzothiazoles  (ISO)
berberine  (EXP,ISO)
Berberrubine  (ISO)
Bergenin  (EXP,ISO)
Besigomsin  (ISO)
beta-aminopropionitrile  (ISO)
beta-carotene  (ISO)
beta-Elemonic acid  (ISO)
beta-ionone  (ISO)
beta-naphthoflavone  (EXP)
Beta-Solamarine  (ISO)
Betanin  (EXP)
betaxolol  (ISO)
betulin  (ISO)
betulinic acid  (ISO)
Betulonic acid  (ISO)
bezafibrate  (EXP)
bicalutamide  (ISO)
bifenthrin  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
boric acid  (EXP,ISO)
boron atom  (EXP)
borrelidin  (ISO)
bortezomib  (ISO)
BQ 123  (EXP,ISO)
BQ 485  (EXP)
brassinin  (ISO)
brassinolide  (ISO)
brazilin  (ISO)
brequinar  (ISO)
bromuconazole  (EXP)
brucine  (ISO)
Brusatol  (EXP,ISO)
bucladesine  (ISO)
budesonide  (ISO)
bufalin  (ISO)
Bufotalin  (ISO)
bupivacaine  (ISO)
buprofezin  (ISO)
butanal  (ISO)
butane-2,3-dione  (ISO)
butein  (ISO)
Butralin  (EXP)
Butylbenzyl phthalate  (EXP,ISO)
Butylphthalide  (EXP)
butyric acid  (ISO)
C.I. Natural Red 20  (EXP,ISO)
cabazitaxel  (ISO)
cadmium acetate  (EXP,ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium nitrate  (EXP)
cadmium sulfate  (ISO)
cadmium sulfide  (ISO)
cadmium telluride  (ISO)
cafestol  (ISO)
caffeine  (EXP)
cajanol  (ISO)
calcidiol  (ISO)
Calcimycin  (ISO)
calciol  (ISO)
calcitriol  (EXP,ISO)
calcium oxalate  (ISO)
calycosin-7-O-beta-D-glucoside  (ISO)
camalexin  (ISO)
camptothecin  (ISO)
Candesartan cilexetil  (EXP)
cannabidiol  (EXP,ISO)
cantharidin  (EXP,ISO)
capillarisin  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
captan  (ISO)
carbachol  (EXP,ISO)
carbamate ester  (ISO)
carbamazepine  (EXP)
carbendazim  (EXP)
CARBENOXOLONE  (EXP,ISO)
carbidopa  (ISO)
carbofuran  (EXP)
carbon dioxide  (EXP)
carbon disulfide  (ISO)
carbon nanotube  (EXP,ISO)
carboplatin  (ISO)
carboxy-PTIO  (ISO)
Cardamonin  (EXP)
Cardanol  (ISO)
carmustine  (ISO)
carnosic acid  (EXP,ISO)
carnosine  (EXP,ISO)
Carnosol  (ISO)
carvacrol  (EXP)
carvedilol  (EXP)
casticin  (EXP,ISO)
catalpol  (ISO)
CEDRELONE  (ISO)
celastrol  (ISO)
celecoxib  (ISO)
ceric oxide  (ISO)
ceritinib  (ISO)
ceruletide  (ISO)
cetrorelix  (EXP,ISO)
chalcones  (ISO)
chelerythrine  (EXP,ISO)
chelidonine  (ISO)
Chikusetsusaponin-IV  (ISO)
Chikusetsusaponin-V  (ISO)
CHIR 99021  (ISO)
chitosan  (EXP,ISO)
chlorambucil  (ISO)
chlordecone  (ISO)
chloroacetic acid  (ISO)
chlorogenic acid  (EXP,ISO)
chlorophyllin  (ISO)
chloroprene  (ISO)
chloroquine  (EXP,ISO)
chlorothalonil  (ISO)
chlorpyrifos  (EXP,ISO)
Cholestane-3,5,6-triol  (EXP)
cholesterol  (EXP,ISO)
choline  (EXP,ISO)
chromium(3+) trichloride  (ISO)
chromium(6+)  (EXP,ISO)
chrysazin  (ISO)
chrysene  (ISO)
chrysin  (EXP,ISO)
cidofovir anhydrous  (ISO)
ciglitazone  (ISO)
cilnidipine  (EXP,ISO)
cilostazol  (EXP,ISO)
cimetidine  (ISO)
Cinobufagin  (ISO)
ciprofloxacin  (ISO)
cisplatin  (EXP,ISO)
Citreoviridin  (EXP,ISO)
citric acid  (ISO)
citronellal  (EXP)
cladribine  (ISO)
clofibrate  (ISO)
clonazepam  (EXP)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
clorgyline  (ISO)
clozapine  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
codeinone  (ISO)
coenzyme Q10  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
colistin  (EXP,ISO)
conjugated linoleic acid  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP,ISO)
copper(II) sulfate  (EXP,ISO)
coptisine  (ISO)
cordycepin  (EXP,ISO)
corilagin  (EXP)
corosolic acid  (EXP,ISO)
corticosterone  (EXP)
Corynoxine B  (ISO)
coumarin  (ISO)
coumarins  (ISO)
coumermycin A1  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP,ISO)
crotonaldehyde  (EXP)
crystal violet  (ISO)
CU-O LINKAGE  (ISO)
cucurbitacin B  (ISO)
cucurbitacin E  (EXP,ISO)
cudraflavone B  (ISO)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
cyanamide  (EXP)
Cyanoginosin  (EXP)
cyclizine  (ISO)
cycloheximide  (ISO)
Cyclopamine  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (ISO)
cyhalothrin  (EXP)
cylindrospermopsin  (EXP,ISO)
cypermethrin  (EXP,ISO)
cytarabine  (ISO)
cytochalasin B  (ISO)
D-glucose  (EXP,ISO)
D-mannitol  (EXP)
D-penicillamine  (ISO)
daidzein  (ISO)
dantrolene  (EXP)
dapagliflozin  (EXP)
dapoxetine  (EXP)
DAPT  (EXP)
daunorubicin  (EXP,ISO)
DDE  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deferiprone  (ISO)
deguelin  (ISO)
dehydrocostus lactone  (ISO)
dehydroepiandrosterone  (EXP,ISO)
dehydroepiandrosterone sulfate  (EXP)
delphinidin  (ISO)
demethoxycurcumin  (ISO)
demethoxyfumitremorgin C  (ISO)
Dendrobine  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
Deoxyschizandrin  (ISO)
desferrioxamine B  (EXP,ISO)
desipramine  (EXP)
desloratadine  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dexmedetomidine  (EXP)
dextran sulfate  (ISO)
dextromethorphan  (EXP)
Di-n-hexyl phthalate  (ISO)
Di-n-octyl phthalate  (ISO)
diallyl disulfide  (EXP,ISO)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP,ISO)
diazoxide  (EXP,ISO)
dibenziodolium  (ISO)
dibenzoylmethane  (ISO)
dibromoacetic acid  (ISO)
Dibromoacetonitrile  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
dichromium trioxide  (ISO)
diclofenac  (EXP,ISO)
dicrotophos  (ISO)
Dictamnine  (ISO)
Didymin  (ISO)
dieckol  (ISO)
dieldrin  (ISO)
diepoxybutane  (ISO)
diethyl maleate  (ISO)
diethyl phthalate  (EXP,ISO)
diethyl sulfate  (ISO)
diethylstilbestrol  (EXP,ISO)
dihydroactinidiolide  (ISO)
diiodine  (ISO)
diisobutyl phthalate  (EXP,ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (EXP,ISO)
dimethomorph  (ISO)
Dimethyl phthalate  (EXP)
dimethyl sulfoxide  (EXP)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
dioscin  (ISO)
diosgenin  (EXP,ISO)
diosmin  (EXP,ISO)
dioxygen  (EXP,ISO)
dipentyl phthalate  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP,ISO)
diprotium oxide  (ISO)
diquat  (EXP,ISO)
disodium cromoglycate  (EXP)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
dithionite(2-)  (EXP,ISO)
dizocilpine maleate  (EXP,ISO)
dobutamine  (ISO)
Dodecyl gallate  (ISO)
domoic acid  (ISO)
donepezil hydrochloride  (EXP,ISO)
dopamine  (ISO)
dorsomorphin  (EXP,ISO)
doxazosin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
drimenol  (ISO)
dronedarone  (EXP)
ebselen  (EXP)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (EXP)
echinacoside  (ISO)
Echinocystic acid  (EXP)
edaravone  (EXP)
edelfosine  (ISO)
elemental boron  (EXP)
elemental selenium  (EXP,ISO)
ellagic acid  (EXP,ISO)
ellipticine  (ISO)
embelin  (ISO)
emodin  (EXP,ISO)
empagliflozin  (EXP)
enalapril  (EXP)
enalaprilat dihydrate  (ISO)
endosulfan  (EXP,ISO)
entacapone  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
epichlorohydrin  (ISO)
epoxomicin  (ISO)
erdosteine  (EXP)
eriocitrin  (ISO)
eritoran  (ISO)
erlotinib hydrochloride  (ISO)
erythromycin estolate  (EXP)
esculetin  (ISO)
esketamine  (ISO)
estramustine  (ISO)
ethanol  (EXP,ISO)
ethidium  (ISO)
ethylbenzene  (EXP)
ethylene glycol  (EXP)
Ethylenethiourea  (ISO)
etodolac  (ISO)
etoposide  (ISO)
eugenol  (ISO)
EUK-134  (ISO)
everolimus  (EXP)
Evodiamine  (ISO)
excitatory amino acid agonist  (ISO)
farrerol  (ISO)
fasudil  (EXP)
favipiravir  (EXP)
febuxostat  (EXP)
fenbendazole  (ISO)
fenhexamid  (ISO)
fenitrothion  (EXP,ISO)
fenofibrate  (EXP,ISO)
fenpyroximate  (ISO)
fenvalerate  (EXP,ISO)
ferric ammonium citrate  (ISO)
ferric oxide  (EXP,ISO)
ferrosoferric oxide  (ISO)
ferrostatin-1  (EXP,ISO)
ferulic acid  (EXP)
finasteride  (EXP)
fingolimod hydrochloride  (ISO)
fipronil  (EXP,ISO)
fisetin  (EXP,ISO)
flavanones  (ISO)
flavokawain B  (ISO)
flavones  (EXP,ISO)
flavonoids  (ISO)
flavonols  (ISO)
fluazinam  (ISO)
flubendazole  (ISO)
flucytosine  (ISO)
fludioxonil  (ISO)
flumethrin  (ISO)
fluoxetine  (EXP,ISO)
flutamide  (EXP)
flutriafol  (EXP)
fluvastatin  (EXP)
folic acid  (EXP,ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
formononetin  (EXP,ISO)
formoterol fumarate  (ISO)
Forsythiaside  (ISO)
fraxetin  (ISO)
fructose  (EXP,ISO)
fucoxanthin  (ISO)
fulvestrant  (EXP,ISO)
fumagillin  (EXP)
fumonisin B1  (ISO)
furan  (EXP)
furosemide  (EXP)
Fusarenone X  (ISO)
gadolinium atom  (ISO)
gadolinium trichloride  (ISO)
Gaillardin  (ISO)
galactose  (EXP,ISO)
galangin  (ISO)
galanthamine  (EXP)
galanthamine Trifluoroacetic acid  (EXP)
Galbanic acid  (ISO)
gallein  (EXP)
gallic acid  (EXP,ISO)
gamma-aminobutyric acid  (EXP)
gamma-hexachlorocyclohexane  (EXP,ISO)
gamma-tocopherol  (ISO)
ganciclovir  (ISO)
Ganoderic acid A  (ISO)
Garcinol  (ISO)
gardenin B  (ISO)
Gastrodin  (EXP,ISO)
gefitinib  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
Genipin  (ISO)
Geniposide  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP,ISO)
Gentiopicrin  (ISO)
Geraniin  (ISO)
geraniol  (EXP,ISO)
geranyl acetate  (ISO)
gingerol  (ISO)
ginkgetin  (ISO)
Ginkgoic acid  (ISO)
Ginkgolide C  (EXP)
ginsenoside Rd  (EXP)
ginsenoside Re  (ISO)
ginsenoside Rg1  (EXP,ISO)
ginsenoside Rg2  (EXP)
Ginsenoside Rg5  (ISO)
glabridin  (ISO)
gliclazide  (ISO)
gliotoxin  (ISO)
glucaric acid  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glyburide  (EXP)
glycerol  (EXP)
glycidol  (EXP)
glycine betaine  (EXP,ISO)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glycyrrhizinic acid  (ISO)
glyoxylic acid  (ISO)
glyphosate  (EXP,ISO)
gold atom  (EXP,ISO)
gold(0)  (EXP,ISO)
Goserelin  (ISO)
gossypol  (ISO)
graphene oxide  (ISO)
graphite  (ISO)
Grifolin  (ISO)
GSK690693  (ISO)
guanidines  (ISO)
guggulsterone  (ISO)
Gyrophoric acid  (ISO)
haloperidol  (EXP)
Harpagoside  (ISO)
hemin  (EXP,ISO)
heparin  (ISO)
heptachlor  (EXP)
herbacetin  (EXP)
hesperetin  (EXP,ISO)
hesperidin  (EXP,ISO)
hexachlorophene  (EXP)
hexadecanoic acid  (EXP,ISO)
hexaflumuron  (EXP)
hexane  (EXP)
hinokiflavone  (ISO)
histamine  (EXP)
homocysteine  (EXP,ISO)
homoeriodictyol  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
hydroxychloroquine  (ISO)
hydroxytyrosol  (EXP,ISO)
hymexazol  (EXP)
hyperforin  (EXP,ISO)
hypoxanthine  (ISO)
icariin  (EXP,ISO)
icariside II  (ISO)
ICI 118551  (ISO)
icosanoid  (EXP)
idarubicin  (ISO)
idelalisib  (ISO)
Idoxifene  (EXP)
ifosfamide  (EXP,ISO)
Ilimaquinone  (ISO)
imidacloprid  (EXP)
Imipenem-cilastatin  (EXP)
imiquimod  (ISO)
indirubin  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
inositol  (ISO)
Inotodiol  (ISO)
iodoacetic acid  (ISO)
iohexol  (EXP,ISO)
Ioversol  (EXP)
iprodione  (EXP)
irbesartan  (EXP,ISO)
irinotecan  (ISO)
iron atom  (ISO)
iron dextran  (EXP,ISO)
iron(0)  (ISO)
iron(2+) sulfate (anhydrous)  (EXP,ISO)
isocarbophos  (ISO)
isoflavones  (EXP,ISO)
isoflurane  (EXP,ISO)
Isoliensinine  (ISO)
isoliquiritigenin  (ISO)
isoniazide  (ISO)
isoorientin  (EXP)
isoprenaline  (EXP,ISO)
isoquinoline-1,5-diol  (ISO)
isorhamnetin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
JBIR-99  (ISO)
juglone  (ISO)
Jujuboside A  (EXP,ISO)
kaempferol  (EXP,ISO)
kahweol  (ISO)
kainic acid  (EXP,ISO)
ketamine  (EXP,ISO)
ketoconazole  (ISO)
KN-93  (ISO)
Kukoamine B  (ISO)
L-1,4-dithiothreitol  (ISO)
L-arginine  (ISO)
L-ascorbic acid  (EXP,ISO)
L-dehydroascorbic acid  (ISO)
L-gamma-glutamyl-L-cysteine  (EXP)
L-glutamic acid  (EXP,ISO)
L-methionine  (EXP,ISO)
L-mimosine  (ISO)
lactacystin  (EXP,ISO)
lactucin  (ISO)
lamivudine  (ISO)
lamotrigine  (EXP)
lansoprazole  (EXP)
lapatinib  (ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (ISO)
lead(0)  (EXP,ISO)
lead(II) chloride  (ISO)
leptomycin B  (ISO)
letrozole  (EXP)
leuprolide  (EXP)
levamisole  (ISO)
levetiracetam  (EXP)
levonorgestrel  (ISO)
Licochalcone A  (ISO)
Licochalcone B  (ISO)
lidocaine  (EXP,ISO)
Liensinine  (ISO)
lignan  (ISO)
limonene  (ISO)
limonin  (ISO)
linalool  (ISO)
linderalactone  (ISO)
linoleic acid  (EXP)
linsidomine  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lipoxin A4  (ISO)
liraglutide  (EXP,ISO)
lisinopril dihydrate  (ISO)
lithium atom  (EXP,ISO)
lithium chloride  (EXP,ISO)
lithium hydride  (EXP,ISO)
loganin  (ISO)
lonafarnib  (ISO)
Longikaurin A  (ISO)
lonidamine  (ISO)
loperamide  (ISO)
losartan  (EXP)
lovastatin  (EXP,ISO)
Lupalbigenin  (ISO)
lupeol  (EXP,ISO)
Lupiwighteone  (ISO)
lupulone  (ISO)
lutein  (ISO)
luteolin  (ISO)
luteolin 7-O-beta-D-glucoside  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
maculosin  (ISO)
madecassic acid  (EXP)
madecassoside  (ISO)
magnesium atom  (EXP)
magnesium oxide  (ISO)
Magnolol  (ISO)
malaoxon  (ISO)
malathion  (EXP,ISO)
malonic acid  (EXP)
malvidin  (ISO)
mancozeb  (EXP,ISO)
maneb  (ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (EXP,ISO)
mebendazole  (ISO)
Mecamylamine  (ISO)
mechlorethamine  (ISO)
mefenamic acid  (ISO)
meglumine amidotrizoate  (EXP,ISO)
MeIQx  (ISO)
melamine  (ISO)
Melarsoprol  (ISO)
melatonin  (EXP,ISO)
melittin  (EXP,ISO)
melphalan  (ISO)
memantine  (EXP,ISO)
menadione  (EXP,ISO)
menaquinone  (EXP)
mercaptopurine  (ISO)
mercury atom  (EXP)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP)
mesalamine  (EXP)
metaproterenol  (ISO)
metformin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methimazole  (EXP)
methomyl  (ISO)
methotrexate  (EXP,ISO)
methoxsalen  (ISO)
methoxychlor  (EXP,ISO)
methyl caffeate  (ISO)
methyl methanesulfonate  (ISO)
methylene blue  (EXP)
methylglyoxal  (EXP,ISO)
methylisothiazolinone  (ISO)
methyllycaconitine  (EXP)
methylmercury chloride  (EXP,ISO)
methylparaben  (ISO)
methylseleninic acid  (EXP)
metipranolol  (EXP)
metiram  (ISO)
metrafenone  (ISO)
mevalonic acid  (EXP,ISO)
mevinphos  (EXP)
microcystin  (EXP)
microcystin RR  (ISO)
microcystin-LR  (EXP,ISO)
midazolam  (EXP)
mifepristone  (ISO)
miglustat  (ISO)
minocycline  (EXP,ISO)
mirtazapine  (ISO)
mitomycin C  (ISO)
Mitoquinone  (ISO)
Mitotane  (EXP,ISO)
MitoTEMPO  (ISO)
mitoxantrone  (ISO)
MK-2206  (ISO)
ML-7  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (EXP,ISO)
monocrotophos  (EXP)
monoethyl phthalate  (ISO)
monosodium L-glutamate  (EXP,ISO)
montelukast  (ISO)
morin  (EXP,ISO)
morphine  (EXP,ISO)
Morroniside  (EXP,ISO)
morusin  (ISO)
mycophenolic acid  (ISO)
myricetin  (ISO)
myricitrin  (ISO)
myristicin  (ISO)
Myrtucommulone A  (ISO)
N'-Nitrosonornicotine  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N,N-dimethylsphingosine  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (ISO)
N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-D-aspartic acid  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-methylnicotinate  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-phosphocreatine  (EXP,ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nabumetone  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
naloxone  (EXP,ISO)
naphthalene  (ISO)
naphthalenes  (ISO)
naringin  (EXP,ISO)
nebivolol  (EXP)
Neferine  (EXP)
neoastilbin  (ISO)
Neoisoliquiritin  (ISO)
neomycin  (ISO)
nerolidol  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel ferrite  (ISO)
nickel subsulfide  (ISO)
nickel sulfate  (EXP,ISO)
niclosamide  (ISO)
nicorandil  (EXP)
nicotinamide  (ISO)
nicotine  (EXP,ISO)
nifedipine  (EXP,ISO)
nigericin  (ISO)
nilotinib  (ISO)
nimesulide  (EXP,ISO)
nimodipine  (EXP,ISO)
Nitidine  (ISO)
nitrendipine  (EXP)
nitric oxide  (ISO)
nitrofen  (EXP)
nitroglycerin  (EXP)
nitroprusside  (EXP,ISO)
nitroxoline  (ISO)
NMN zwitterion  (ISO)
NMS-873  (ISO)
nobiletin  (EXP,ISO)
nocodazole  (ISO)
Nodularin  (ISO)
Nonylphenol  (EXP,ISO)
Norbinaltorphimine  (ISO)
NORCANTHARIDIN  (ISO)
Norethindrone enanthate  (EXP)
norfloxacin  (ISO)
norwogonin  (EXP,ISO)
notoginsenoside R1  (EXP,ISO)
NS 1619  (ISO)
NS-398  (ISO)
Nutlin-3  (ISO)
o-anisidine  (ISO)
o-cresol  (EXP)
Obacunone  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
octyl gallate  (ISO)
okadaic acid  (ISO)
olanzapine  (EXP)
olaparib  (ISO)
oleanolic acid  (ISO)
oleic acid  (ISO)
olesoxime  (ISO)
oleuropein  (EXP,ISO)
oligomycin A  (ISO)
oligopeptide  (ISO)
Olmesartan medoxomil  (EXP)
omacetaxine mepesuccinate  (ISO)
omeprazole  (ISO)
Ophiopogonin D  (ISO)
orciprenaline  (ISO)
organoselenium compound  (EXP)
oridonin  (EXP,ISO)
orlistat  (EXP)
oroxylin A  (ISO)
osthole  (ISO)
ouabain  (ISO)
oxalic acid  (ISO)
oxaliplatin  (EXP,ISO)
oxidopamine  (EXP,ISO)
oxomalononitrile  (ISO)
oxytocin  (EXP)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
Pachymic acid  (ISO)
paclitaxel  (EXP,ISO)
paeoniflorin  (EXP,ISO)
Paeonol  (EXP,ISO)
palmatine  (ISO)
Palmitic acid(d3)  (ISO)
pamidronate  (ISO)
Panaxynol  (EXP)
Panduratin A  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
paricalcitol  (ISO)
parthenolide  (ISO)
pefloxacin  (ISO)
pemetrexed  (ISO)
pendimethalin  (EXP)
Pendulone  (ISO)
pentanal  (ISO)
pentobarbital  (EXP)
Pentoxifylline  (EXP)
perfluoroheptanoic acid  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
perfluoroundecanoic acid  (EXP)
perillyl alcohol  (ISO)
permethrin  (EXP,ISO)
peroxynitrous acid  (EXP)
pevonedistat  (ISO)
PF-3758309  (ISO)
Phellopterin  (ISO)
phenazine-1-carboxylic acid  (ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP,ISO)
phenylhydrazine  (ISO)
phenytoin  (ISO)
PhIP  (ISO)
phloretin  (EXP)
phloroglucinol  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphatidylcholine  (ISO)
phosphoramide mustard  (EXP)
phylloquinone  (EXP,ISO)
phytol  (ISO)
phytosphingosine  (ISO)
piclamilast  (EXP)
picoxystrobin  (ISO)
pifithrin-alpha hydrobromide  (EXP,ISO)
pimozide  (ISO)
pinostrobin  (EXP,ISO)
pioglitazone  (EXP)
piperazine  (ISO)
piperidine  (ISO)
piperine  (ISO)
pirarubicin  (ISO)
pirfenidone  (ISO)
pirinixic acid  (EXP,ISO)
PK-11195  (EXP,ISO)
platinum  (ISO)
platinum(0)  (ISO)
platycodin D  (ISO)
plumbagin  (EXP)
poly(I:C)  (ISO)
Polygodial  (ISO)
polymyxin B2  (ISO)
polysulfur  (ISO)
ponatinib  (ISO)
Ponicidin  (ISO)
porphyrins  (ISO)
potassium bromate  (EXP)
potassium chromate  (ISO)
potassium cyanide  (EXP)
potassium dichromate  (EXP,ISO)
potassium iodide  (EXP)
Pramanicin  (ISO)
Pranoprofen  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
proanthocyanidin  (EXP,ISO)
probenecid  (ISO)
probucol  (EXP)
procyanidin  (ISO)
procyanidin B2  (ISO)
prodigiosin  (EXP)
progesterone  (EXP,ISO)
promethazine  (ISO)
propionic acid  (EXP)
propofol  (EXP,ISO)
propranolol  (EXP,ISO)
propylparaben  (ISO)
prostaglandin E2  (ISO)
Protolichesterinic acid  (ISO)
psoralen  (ISO)
pterostilbene  (ISO)
puerarin  (EXP,ISO)
punicalagin  (EXP,ISO)
purine-6-thiol  (ISO)
purmorphamine  (EXP)
puromycin  (ISO)
putrescine  (EXP)
pyrethrins  (EXP,ISO)
pyridaben  (ISO)
Pyridostigmine bromide  (ISO)
pyridoxal 5'-phosphate  (EXP)
pyrroles  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
pyrroloquinoline quinone  (ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
quercetin 3-O-beta-D-glucofuranoside  (EXP,ISO)
quercetin 3-O-beta-D-glucopyranoside  (EXP,ISO)
quercetin 4'-O-beta-D-glucopyranoside  (ISO)
quinazolines  (ISO)
quinolinic acid  (EXP)
quinoxyfen  (ISO)
quizartinib  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ramipril  (EXP)
ranitidine  (ISO)
reactive oxygen species  (ISO)
Rebamipide  (ISO)
remdesivir  (ISO)
reserpine  (EXP)
resolvin D1  (EXP)
resveratrol  (EXP,ISO)
riboflavin  (ISO)
rifampicin  (ISO)
Riluzole  (EXP)
rimonabant  (ISO)
ritonavir  (ISO)
rivastigmine  (EXP)
Ro 31-8220  (EXP)
robinin  (EXP)
rocaglamide  (ISO)
roflumilast  (EXP,ISO)
rolipram  (EXP)
ropinirole  (ISO)
rosmarinic acid  (EXP,ISO)
rosuvastatin calcium  (ISO)
rotenone  (EXP,ISO)
rottlerin  (ISO)
royal jelly  (EXP,ISO)
RU 58668  (ISO)
rubitecan  (ISO)
ruthenium atom  (EXP)
rutin  (EXP,ISO)
ruxolitinib  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-allylcysteine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
S-nitrosoglutathione  (ISO)
S63845  (ISO)
saccharin  (EXP)
safrole  (ISO)
Salidroside  (EXP,ISO)
Salinomycin  (ISO)
Salmeterol xinafoate  (ISO)
salubrinal  (EXP,ISO)
Salvianolic acid A  (EXP)
salvianolic acid B  (EXP)
Sanggenon C  (EXP,ISO)
sanguinarine  (EXP,ISO)
sappanchalcone  (ISO)
sarin  (EXP)
sarpogrelate  (ISO)
saxagliptin  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
SB-239063  (EXP)
SCH 23390  (EXP,ISO)
SCH772984  (ISO)
sclareol  (ISO)
scoparone  (ISO)
scopolamine  (EXP,ISO)
scopoletin  (EXP)
scutellarin  (ISO)
Se-methyl-L-selenocysteine  (EXP,ISO)
Se-methylselenocysteine  (EXP,ISO)
selenium atom  (EXP,ISO)
selenocystine  (ISO)
selenomethionine  (ISO)
semaglutide  (EXP,ISO)
semilicoisoflavone B  (ISO)
serpentine asbestos  (ISO)
sertraline  (ISO)
Sesamol  (ISO)
sevoflurane  (EXP,ISO)
Shikonin  (EXP,ISO)
sibutramine  (ISO)
sildenafil citrate  (EXP,ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simazine  (ISO)
simvastatin  (EXP,ISO)
sinapic acid  (EXP)
sirolimus  (EXP,ISO)
sirtinol  (ISO)
SNX-2112  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (EXP)
sodium chloride  (EXP,ISO)
sodium cholate  (ISO)
sodium chromate  (ISO)
sodium dichromate  (EXP,ISO)
sodium disulfite  (ISO)
sodium fluoride  (EXP,ISO)
sodium nitrite  (EXP)
sodium silicate  (EXP)
Sophoricoside  (ISO)
sorafenib  (ISO)
soybean oil  (EXP)
spermine  (EXP,ISO)
sphingosine 1-phosphate  (ISO)
spironolactone  (EXP)
Spiroquinazoline  (ISO)
squalene  (EXP)
stattic  (ISO)
staurosporine  (ISO)
stavudine  (ISO)
sterigmatocystin  (ISO)
stilbenoid  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
styrene oxide  (EXP,ISO)
succimer  (EXP)
sucrose  (EXP)
sulfadimethoxine  (EXP)
sulfaphenazole  (ISO)
sulfasalazine  (EXP,ISO)
sulforaphane  (ISO)
sulfur atom  (ISO)
sulfur dioxide  (ISO)
sulindac  (EXP,ISO)
sulindac sulfide  (ISO)
sulpiride  (ISO)
sunitinib  (ISO)
Sunset Yellow FCF  (EXP)
surfactin  (ISO)
surfactin C  (ISO)
Swertiamarin  (EXP,ISO)
syringic acid  (EXP,ISO)
syringin  (ISO)
T-2 toxin  (EXP,ISO)
tacrine  (ISO)
tacrolimus hydrate  (EXP,ISO)
tadalafil  (EXP,ISO)
taiwanin C  (ISO)
talazoparib  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
Tanshinone I  (ISO)
Tariquidar  (ISO)
taurine  (EXP)
taurocholic acid  (ISO)
tauroursodeoxycholic acid  (EXP,ISO)
tazarotene  (ISO)
tebuconazole  (EXP,ISO)
telmisartan  (EXP)
temozolomide  (ISO)
TEMPO  (ISO)
Temsirolimus  (ISO)
terazosin  (ISO)
Terfenadine  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (EXP)
tetrachloroethene  (ISO)
tetrachlorohydroquinone  (ISO)
tetrachloromethane  (EXP,ISO)
tetrahydrocurcumin  (ISO)
tetrahydropalmatine  (ISO)
tetramethylpyrazine  (EXP)
tetrathiomolybdate(2-)  (ISO)
thalidomide  (EXP,ISO)
thapsigargin  (EXP,ISO)
theaflavin  (EXP,ISO)
Theaflavin 3,3'-digallate  (EXP,ISO)
theophylline  (ISO)
thiamethoxam  (ISO)
thiamine(1+) chloride  (EXP,ISO)
thioacetamide  (EXP,ISO)
thiostrepton  (ISO)
Thiotepa  (ISO)
thymol  (EXP,ISO)
thymol sulfate(1-)  (EXP,ISO)
thymoquinone  (EXP,ISO)
thyroxine  (EXP)
tigecycline  (EXP)
tin(II) chloride (anhydrous)  (EXP)
Tiron  (ISO)
titanium dioxide  (EXP,ISO)
tocopherol  (ISO)
Tomentosin  (ISO)
toosendanin  (ISO)
topotecan  (ISO)
Torularhodin  (ISO)
torulene  (ISO)
tramadol  (EXP)
trametinib  (ISO)
tranexamic acid  (ISO)
trans-anethole  (EXP)
trans-cinnamic acid  (EXP)
trans-piceid  (ISO)
tranylcypromine  (EXP)
triacetin  (ISO)
triazoles  (ISO)
tributylstannane  (EXP,ISO)
Tributyltin oxide  (EXP)
tributyrin  (ISO)
tricetin  (ISO)
trichlorfon  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
trifluoperazine  (ISO)
trilobatin  (EXP)
trimethyltin  (ISO)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
Triptolide  (EXP,ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
tropisetron  (EXP)
Tubeimoside I  (ISO)
tubocurarine  (ISO)
tunicamycin  (ISO)
tyrphostin AG 1478  (ISO)
umbelliferone  (EXP,ISO)
uranium atom  (ISO)
urethane  (ISO)
Urolithin A  (EXP,ISO)
ursodeoxycholic acid  (EXP,ISO)
ursolic acid  (ISO)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vanadyl sulfate  (ISO)
vancomycin  (EXP)
vemurafenib  (ISO)
venetoclax  (ISO)
venlafaxine hydrochloride  (EXP)
venom  (ISO)
verapamil  (ISO)
Vernodalin  (ISO)
Vernodalol  (ISO)
verteporfin  (EXP)
Vicanicin  (ISO)
vildagliptin  (EXP)
vinclozolin  (ISO)
vincristine  (EXP,ISO)
vindesine  (ISO)
Vinpocetine  (EXP)
vismodegib  (ISO)
vitamin D  (ISO)
vitamin E  (EXP,ISO)
vitexin  (ISO)
vorinostat  (EXP,ISO)
vortioxetine  (EXP)
warfarin  (EXP)
water  (ISO)
wedelolactone  (ISO)
WIN 55212-2  (ISO)
withaferin A  (EXP,ISO)
wogonin  (ISO)
wortmannin  (EXP,ISO)
xanthohumol  (EXP,ISO)
Xanthorrhizol  (ISO)
XAV939  (ISO)
xenon atom  (EXP)
xenon(0)  (EXP)
XMU-MP-1  (ISO)
Y-27632  (EXP,ISO)
ytterbium  (ISO)
zearalenone  (EXP,ISO)
zebularine  (ISO)
zerumbone  (EXP,ISO)
zidovudine  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc molecular entity  (ISO)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (EXP,ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zingerone  (EXP,ISO)
zingiberene  (EXP)
ziram  (EXP)
zoledronic acid  (ISO)
zolmitriptan  (EXP)
zoxamide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament organization  (ISO)
animal organ morphogenesis  (ISO)
apoptotic mitochondrial changes  (ISO)
apoptotic process  (IEA,ISO)
autophagy  (IEA)
axon regeneration  (ISO)
axonogenesis  (ISO)
B cell differentiation  (ISO)
B cell homeostasis  (ISO)
B cell lineage commitment  (ISO)
B cell proliferation  (ISO)
B cell receptor signaling pathway  (ISO)
behavioral fear response  (ISO)
branching involved in ureteric bud morphogenesis  (ISO)
CD8-positive, alpha-beta T cell lineage commitment  (ISO)
cell morphogenesis  (ISO)
cell population proliferation  (ISO)
cell-cell adhesion  (ISO)
cellular response to fluoride  (IEP)
cellular response to glucose starvation  (ISO)
cellular response to glucose stimulus  (IEP)
cellular response to hydrogen peroxide  (IEP)
cellular response to hypoxia  (IEA,IEP,ISO)
cellular response to L-glutamate  (IEP)
cerebral cortex development  (IEP)
cochlear nucleus development  (ISO)
defense response to virus  (ISO)
developmental growth  (ISO)
developmental pigmentation  (ISO)
digestive tract morphogenesis  (ISO)
DNA damage response  (ISO)
ear development  (ISO)
endoplasmic reticulum calcium ion homeostasis  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (IBA,ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
focal adhesion assembly  (ISO)
gland morphogenesis  (ISO)
glial cell apoptotic process  (IEP)
glomerulus development  (ISO)
gonad development  (IEA)
hair follicle morphogenesis  (ISO)
hemopoiesis  (ISO)
homeostasis of number of cells within a tissue  (ISO)
immune system development  (ISO)
intracellular calcium ion homeostasis  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IBA,ISO)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (ISO)
kidney development  (ISO)
leukocyte homeostasis  (ISO)
liver regeneration  (IEP)
lymphocyte homeostasis  (ISO)
lymphoid progenitor cell differentiation  (ISO)
male gonad development  (ISO)
melanin metabolic process  (ISO)
melanocyte differentiation  (ISO)
mesenchymal cell development  (ISO)
metanephros development  (ISO)
negative regulation of anoikis  (ISO)
negative regulation of apoptotic process  (IDA,IEA,IMP,ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of autophagy  (ISO,ISS)
negative regulation of calcium ion transport into cytosol  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (IMP)
negative regulation of cell growth  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cellular pH reduction  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
negative regulation of G1/S transition of mitotic cell cycle  (ISO)
negative regulation of intrinsic apoptotic signaling pathway  (ISO)
negative regulation of mitotic cell cycle  (ISO)
negative regulation of myeloid cell apoptotic process  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of ossification  (ISO)
negative regulation of osteoblast proliferation  (ISO)
negative regulation of retinal cell programmed cell death  (ISO)
neuron apoptotic process  (ISO)
oligodendrocyte differentiation  (IEP)
oocyte development  (ISO)
organ growth  (ISO)
ossification  (ISO)
ovarian follicle development  (IEA,IEP,ISO)
peptidyl-serine phosphorylation  (ISO)
peptidyl-threonine phosphorylation  (ISO)
pigment granule organization  (ISO)
pigmentation  (ISO)
positive regulation of apoptotic process  (IBA)
positive regulation of B cell proliferation  (ISO)
positive regulation of catalytic activity  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of developmental pigmentation  (ISO)
positive regulation of melanocyte differentiation  (ISO)
positive regulation of multicellular organism growth  (ISO)
positive regulation of neuron maturation  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of skeletal muscle fiber development  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
post-embryonic development  (ISO)
protein dephosphorylation  (ISO)
protein polyubiquitination  (ISO)
reactive oxygen species metabolic process  (ISO)
regulation of apoptotic process  (IEA,ISO)
regulation of autophagy  (ISO)
regulation of calcium ion transport  (ISO)
regulation of catalytic activity  (ISO)
regulation of cell cycle  (ISO)
regulation of cell-matrix adhesion  (ISO)
regulation of developmental pigmentation  (ISO)
regulation of gene expression  (ISO)
regulation of glycoprotein biosynthetic process  (ISO)
regulation of growth  (ISO)
regulation of mitochondrial membrane permeability  (ISO,ISS)
regulation of mitochondrial membrane potential  (ISO,ISS)
regulation of neuron apoptotic process  (IEP)
regulation of nitrogen utilization  (ISO)
regulation of programmed cell death  (ISO)
regulation of protein localization  (ISO)
regulation of protein stability  (ISO)
regulation of viral genome replication  (ISO)
release of cytochrome c from mitochondria  (IBA,ISO,ISS)
renal system process  (ISO)
response to aluminum ion  (IEP)
response to amyloid-beta  (IEP)
response to anesthetic  (IEP)
response to caffeine  (IEP)
response to cAMP  (IEP)
response to copper ion  (IEP)
response to corticosterone  (IEP)
response to cytokine  (IEP,ISO)
response to electrical stimulus  (IEP)
response to erythropoietin  (IEP)
response to estrogen  (IEP)
response to ethanol  (IDA,IEP)
response to folic acid  (IEP)
response to gamma radiation  (ISO)
response to glucocorticoid  (IEA,ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (IEP)
response to insulin  (IEP)
response to insulin-like growth factor stimulus  (IEP)
response to iron ion  (ISO)
response to ischemia  (IEA,IEP,ISO)
response to L-ascorbic acid  (IEP)
response to monosaccharide  (IEP)
response to nicotine  (IEP,ISO)
response to nutrient  (IEP)
response to oxidative stress  (ISO)
response to peptide hormone  (IEP)
response to phenylpropanoid  (IEP)
response to steroid hormone  (ISO)
response to toxic substance  (ISO)
response to UV-B  (ISO)
response to vitamin E  (IEP)
response to xenobiotic stimulus  (IEP,ISO)
spleen development  (ISO)
swimming behavior  (IEP)
T cell differentiation  (ISO)
T cell differentiation in thymus  (ISO)
T cell homeostasis  (ISO)
T cell lineage commitment  (ISO)
thymus development  (ISO)
transmembrane transport  (IEA)
ureteric bud development  (ISO)

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. The Bcl-2 apoptotic switch in cancer development and therapy. Adams JM and Cory S, Oncogene. 2007 Feb 26;26(9):1324-37.
2. Neuroprotective Effect of Nanodiamond in Alzheimer's Disease Rat Model: a Pivotal Role for Modulating NF-kappaB and STAT3 Signaling. Alawdi SH, etal., Mol Neurobiol. 2016 Feb 20.
3. Lung injury after ischemia-reperfusion of small intestine in rats involves apoptosis of type II alveolar epithelial cells mediated by TNF-alpha and activation of Bid pathway. An S, etal., Apoptosis. 2007 Nov;12(11):1989-2001. doi: 10.1007/s10495-007-0125-1.
4. Combination of PTEN gene therapy and radiation inhibits the growth of human prostate cancer xenografts. Anai S, etal., Hum Gene Ther. 2006 Oct;17(10):975-84.
5. BAG-4/SODD and associated antiapoptotic proteins are linked to aggressiveness of epithelial ovarian cancer. Annunziata CM, etal., Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6585-92.
6. The AA genotype of the regulatory BCL2 promoter polymorphism ( 938C>A) is associated with a favorable outcome in lymph node negative invasive breast cancer patients. Bachmann HS, etal., Clin Cancer Res. 2007 Oct 1;13(19):5790-7.
7. Effects of sulfur dioxide on apoptosis-related gene expressions in lungs from rats. Bai J and Meng Z, Regul Toxicol Pharmacol. 2005 Dec;43(3):272-9. Epub 2005 Oct 26.
8. Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats. Baker DJ and Hepple RT, Exp Gerontol. 2006 Nov;41(11):1149-56. Epub 2006 Oct 6.
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Genomics

Comparative Map Data
Bcl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81323,204,464 - 23,366,900 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1323,204,464 - 23,366,900 (-)EnsemblGRCr8
mRatBN7.21322,689,783 - 22,853,920 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1323,013,354 - 23,175,038 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,297,817 - 24,459,509 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01322,983,528 - 23,145,223 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,605,426 - 26,769,374 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,605,426 - 26,769,374 (-)Ensemblrn6Rnor6.0
Rnor_5.01331,758,213 - 31,920,775 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41312,730,736 - 12,905,108 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1322,550,362 - 22,711,143 (-)NCBICelera
RGSC_v3.11312,730,735 - 12,905,108 (-)NCBI
Cytogenetic Map13p11NCBI
BCL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,123,346 - 63,320,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1863,123,346 - 63,320,128 (-)Ensemblhg38GRCh38
GRCh371860,790,579 - 60,987,002 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361858,941,559 - 59,137,593 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341858,941,558 - 59,136,910NCBI
Celera1857,509,356 - 57,706,116 (-)NCBICelera
Cytogenetic Map18q21.33NCBI
HuRef1857,487,199 - 57,684,751 (-)NCBIHuRef
CHM1_11860,786,149 - 60,982,536 (-)NCBICHM1_1
T2T-CHM13v2.01863,326,497 - 63,525,122 (-)NCBIT2T-CHM13v2.0
Bcl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,465,906 - 106,642,020 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1106,465,908 - 106,642,004 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381106,538,176 - 106,714,290 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,538,178 - 106,714,274 (-)Ensemblmm10GRCm38
MGSCv371108,434,756 - 108,610,867 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361108,365,740 - 108,541,849 (-)NCBIMGSCv36mm8
Celera1109,386,734 - 109,563,656 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map149.76NCBI
Bcl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540246,916,266 - 47,084,485 (-)Ensembl
ChiLan1.0NW_00495540246,911,125 - 47,084,214 (-)NCBIChiLan1.0ChiLan1.0
BCL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21780,632,173 - 80,830,186 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11866,324,787 - 66,522,695 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01856,481,212 - 56,679,012 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11859,797,184 - 59,993,298 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1859,802,443 - 59,992,100 (-)EnsemblpanPan2panpan1.1
BCL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,733,849 - 13,900,653 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,731,406 - 13,900,658 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha114,699,877 - 14,866,689 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0113,595,394 - 13,762,294 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,595,394 - 13,762,292 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,633,483 - 13,799,972 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,562,764 - 13,729,319 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,811,587 - 13,978,482 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bcl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,970,171 - 27,134,608 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364972,210,334 - 2,210,921 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364972,209,136 - 2,373,580 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,337,522 - 158,518,879 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,824,218 - 175,994,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,440,560 - 16,643,187 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1816,441,733 - 16,637,895 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660609,049,043 - 9,247,859 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247928,859,522 - 9,031,344 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247928,854,345 - 9,032,727 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcl2
2665 total Variants
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir16-2rno-miR-16-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19232449
Mir1rno-miR-1-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI19506341
Mir15brno-miR-15b-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19232449

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:24
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000003768
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134785618Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131244842148744906Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131228551734884386Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13308875548088755Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131244842147969993Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13600200837088115Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
2303031Bp326Blood pressure QTL 326arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131228551723516549Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13143736554Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131228551734884386Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13134785618Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
D13Kyo4   No map positions available.
RH142296  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81323,366,677 - 23,366,834 (+)Marker Load Pipeline
mRatBN7.21322,852,015 - 22,852,172 (+)MAPPERmRatBN7.2
Rnor_6.01326,769,152 - 26,769,308NCBIRnor6.0
Rnor_5.01331,919,628 - 31,919,784UniSTSRnor5.0
RGSC_v3.41312,904,886 - 12,905,042UniSTSRGSC3.4
Celera1322,710,921 - 22,711,077UniSTS
Cytogenetic Map13p13UniSTS
PMC150726P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,851,683 - 22,851,977 (+)MAPPERmRatBN7.2
Rnor_6.01326,768,820 - 26,769,113NCBIRnor6.0
Rnor_5.01331,919,296 - 31,919,589UniSTSRnor5.0
RGSC_v3.41312,904,554 - 12,904,847UniSTSRGSC3.4
Celera1322,710,589 - 22,710,882UniSTS
Cytogenetic Map13p13UniSTS
PMC16825P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,851,425 - 22,852,128 (+)MAPPERmRatBN7.2
Rnor_6.01326,768,562 - 26,769,264NCBIRnor6.0
Rnor_5.01331,919,038 - 31,919,740UniSTSRnor5.0
RGSC_v3.41312,904,296 - 12,904,998UniSTSRGSC3.4
Celera1322,710,331 - 22,711,033UniSTS
Cytogenetic Map13p13UniSTS
RH131732  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,737,170 - 22,737,383 (+)MAPPERmRatBN7.2
Rnor_6.01326,653,324 - 26,653,536NCBIRnor6.0
Rnor_5.01331,805,570 - 31,805,782UniSTSRnor5.0
RGSC_v3.41312,778,905 - 12,779,117UniSTSRGSC3.4
Celera1322,597,379 - 22,597,591UniSTS
Cytogenetic Map13p13UniSTS
PMC104155P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,851,427 - 22,851,695 (+)MAPPERmRatBN7.2
Rnor_6.01326,768,564 - 26,768,831NCBIRnor6.0
Rnor_5.01331,919,040 - 31,919,307UniSTSRnor5.0
RGSC_v3.41312,904,298 - 12,904,565UniSTSRGSC3.4
Celera1322,710,333 - 22,710,600UniSTS
Cytogenetic Map13p13UniSTS
PMC125347P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,851,488 - 22,851,935 (+)MAPPERmRatBN7.2
Rnor_6.01326,768,625 - 26,769,071NCBIRnor6.0
Rnor_5.01331,919,101 - 31,919,547UniSTSRnor5.0
RGSC_v3.41312,904,359 - 12,904,805UniSTSRGSC3.4
Celera1322,710,394 - 22,710,840UniSTS
Cytogenetic Map13p13UniSTS
UniSTS:461954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,851,514 - 22,851,862 (+)MAPPERmRatBN7.2
Rnor_6.01326,768,651 - 26,768,998NCBIRnor6.0
Rnor_5.01331,919,127 - 31,919,474UniSTSRnor5.0
RGSC_v3.41312,904,385 - 12,904,732UniSTSRGSC3.4
Celera1322,710,420 - 22,710,767UniSTS
Cytogenetic Map13p13UniSTS
PMC316415P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,851,944 - 22,852,544 (+)MAPPERmRatBN7.2
Rnor_6.01326,769,081 - 26,769,680NCBIRnor6.0
Rnor_5.01331,919,557 - 31,920,156UniSTSRnor5.0
RGSC_v3.41312,904,815 - 12,905,414UniSTSRGSC3.4
Celera1322,710,850 - 22,711,449UniSTS
Cytogenetic Map13p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003768   ⟹   ENSRNOP00000003768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1326,605,426 - 26,769,374 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092763   ⟹   ENSRNOP00000075954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1326,767,685 - 26,768,708 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099529   ⟹   ENSRNOP00000093136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123916   ⟹   ENSRNOP00000102288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,256,014 - 23,366,863 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000141945   ⟹   ENSRNOP00000104403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,318,045 - 23,366,863 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000147171   ⟹   ENSRNOP00000112134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,354,027 - 23,366,863 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156655   ⟹   ENSRNOP00000106668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1323,204,464 - 23,366,900 (-)Ensembl
RefSeq Acc Id: NM_016993   ⟹   NP_058689
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81323,204,464 - 23,366,900 (-)NCBI
mRatBN7.21322,689,783 - 22,852,238 (-)NCBI
Rnor_6.01326,605,426 - 26,769,374 (-)NCBI
Rnor_5.01331,758,213 - 31,920,775 (-)NCBI
RGSC_v3.41312,730,736 - 12,905,108 (-)RGD
Celera1322,550,362 - 22,711,143 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058689 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA53662 (Get FASTA)   NCBI Sequence Viewer  
  AAA77687 (Get FASTA)   NCBI Sequence Viewer  
  AAD48410 (Get FASTA)   NCBI Sequence Viewer  
  AAP47159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000106668
GenBank Protein P49950 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058689   ⟸   NM_016993
- UniProtKB: Q64032 (UniProtKB/Swiss-Prot),   Q62837 (UniProtKB/Swiss-Prot),   P49950 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075954   ⟸   ENSRNOT00000092763
Ensembl Acc Id: ENSRNOP00000003768   ⟸   ENSRNOT00000003768
Ensembl Acc Id: ENSRNOP00000093136   ⟸   ENSRNOT00000099529
Ensembl Acc Id: ENSRNOP00000104403   ⟸   ENSRNOT00000141945
Ensembl Acc Id: ENSRNOP00000112134   ⟸   ENSRNOT00000147171
Ensembl Acc Id: ENSRNOP00000106668   ⟸   ENSRNOT00000156655
Ensembl Acc Id: ENSRNOP00000102288   ⟸   ENSRNOT00000123916

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49950-F1-model_v2 AlphaFold P49950 1-236 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2199 AgrOrtholog
BioCyc Gene G2FUF-18606 BioCyc
Ensembl Genes ENSRNOG00000002791 Ensembl
  ENSRNOG00000067693 Ensembl
  ENSRNOG00000077679 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000156655 ENTREZGENE
Gene3D-CATH 1.10.437.10 UniProtKB/Swiss-Prot
InterPro Apop_reg_Bcl2 UniProtKB/Swiss-Prot
  Bcl-2_BH1-3 UniProtKB/Swiss-Prot
  Bcl2-like UniProtKB/Swiss-Prot
  Bcl2/BclX UniProtKB/Swiss-Prot
  Bcl2_BH1_motif_CS UniProtKB/Swiss-Prot
  Bcl2_BH2_motif_CS UniProtKB/Swiss-Prot
  Bcl2_BH3_motif_CS UniProtKB/Swiss-Prot
  Bcl2_BH4 UniProtKB/Swiss-Prot
  Bcl2_BH4_motif_CS UniProtKB/Swiss-Prot
  Blc2-like_sf UniProtKB/Swiss-Prot
  Blc2_fam UniProtKB/Swiss-Prot
KEGG Report rno:24224 UniProtKB/Swiss-Prot
NCBI Gene 24224 ENTREZGENE
PANTHER APOPTOSIS REGULATOR BCL-2 UniProtKB/Swiss-Prot
  PTHR11256 UniProtKB/Swiss-Prot
Pfam Bcl-2 UniProtKB/Swiss-Prot
  BH4 UniProtKB/Swiss-Prot
PharmGKB BCL2 RGD
PhenoGen Bcl2 PhenoGen
PRINTS APOPREGBCL2 UniProtKB/Swiss-Prot
  BCL2FAMILY UniProtKB/Swiss-Prot
PROSITE BCL2_FAMILY UniProtKB/Swiss-Prot
  BH1 UniProtKB/Swiss-Prot
  BH2 UniProtKB/Swiss-Prot
  BH3 UniProtKB/Swiss-Prot
  BH4_1 UniProtKB/Swiss-Prot
  BH4_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002791 RatGTEx
  ENSRNOG00000067693 RatGTEx
  ENSRNOG00000077679 RatGTEx
SMART BCL UniProtKB/Swiss-Prot
  BH4 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56854 UniProtKB/Swiss-Prot
UniProt A0ABK0LCE2_RAT UniProtKB/TrEMBL
  A0ABK0LHS8_RAT UniProtKB/TrEMBL
  A0ABK0LXU8_RAT UniProtKB/TrEMBL
  A0ABK0M473_RAT UniProtKB/TrEMBL
  BCL2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q62837 ENTREZGENE
  Q64032 ENTREZGENE
UniProt Secondary Q62837 UniProtKB/Swiss-Prot
  Q64032 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Bcl2  BCL2, apoptosis regulator  Bcl2  B cell leukemia/lymphoma 2  Data merged from RGD:150341388 737654 PROVISIONAL
2022-01-06 Bcl2  B cell leukemia/lymphoma 2  ENSRNOG00000067693    Symbol and/or name change 19259462 PROVISIONAL
2021-08-31 ENSRNOG00000067693        Symbol and Name status set to provisional 45752 PROVISIONAL
2016-06-22 Bcl2  BCL2, apoptosis regulator  Bcl2  B-cell CLL/lymphoma 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Bcl2  B-cell CLL/lymphoma 2  Bcl2  B-cell leukemia/lymphoma 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Bcl2  B-cell leukemia/lymphoma 2      Symbol and Name status set to approved 625702 APPROVED
2002-06-10 Bcl2  B-cell leukemia/lymphoma 2      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease combined DTX and PMEDAP treatment inhibited or significantly reduced lymphomas 70255
gene_expression mitochondrial level decreased with age 70304
gene_expression protein expression was greatest in fast-twitch glycolytic muscles than in slow-twitch or oxidative muscles 1298696
gene_expression expression is decreased neuronally after hypoxia in SHRSP rat strain compared with WKY rat strain 1553895
gene_mutations_overexpression overexpression is sufficient for survival of retinal ganglion cells (RGCs) without glial or trophic support 70671
gene_process anti-apoptotic 70304
gene_regulation expression increased by progesterone (and 19-norprogesterone) alone or in combination with estrogen 625452