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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:23527
Term: cytochalasin B
Definition: An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments.
Chemical ID: MESH:D003571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionISORGD:7331006480464CTDCytochalasin B results in decreased expression of BCL2 protein

PMID:27640744
Bcl2multiple interactionsISORGD:7331006480464CTD1 2-bis2-aminophenoxyethane N N N' N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cytochalasin B results in decreased expression of BCL2 protein]

PMID:27640744
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