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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:9141
Term: silver(0)
Definition: An elemental silver that has formula Ag.
Chemical ID: MESH:D012834
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2affects expressionISOBCL2 (Homo sapiens)6480464CTDSilver analog affects the expression of BCL2 mRNA; Silver analog affects the expression of BCL2 proteinPMID:24849675
Bcl2decreases expressionISOBcl2 (Mus musculus)6480464CTDSilver results in decreased expression of BCL2 mRNA; Silver results in decreased expression of BCL2 proteinPMID:27131904 PMID:29665414
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDSilver results in decreased expression of BCL2 mRNAPMID:21611810
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD[Silver analog co-treated with Citric Acid] results in increased expression of BCL2 mRNA; [Silver analog co-treated with Polyethylene Glycols] results in increased expression of BCL2 mRNAPMID:27021274
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