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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:38635
Term: 3-methyladenine
Definition: A methyladenine that is adenine substituted with a methyl group at position N-3.
Chemical ID: MESH:C025946
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTD3-methyladenine inhibits the reaction [citreoviridin results in decreased expression of BCL2 protein]PMID:31419397
Bcl2multiple interactionsISOBcl2 (Mus musculus)6480464CTD3-methyladenine inhibits the reaction [Alpha-Amanitin results in decreased expression of BCL2 protein]PMID:35175747
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD3-methyladenine inhibits the reaction [alisol A 24-acetate results in decreased expression of BCL2 protein]; 3-methyladenine inhibits the reaction [alisol B 23-acetate results in decreased expression of BCL2 protein]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2]; 3-methyladenine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; 3-methyladenine inhibits the reaction [beta-ionone results in decreased expression of BCL2 protein]; 3-methyladenine inhibits the reaction [Nicotine results in decreased expression of BCL2 protein]; [3-methyladenine co-treated with Amiodarone] results in decreased expression of BCL2 proteinPMID:23912912 PMID:25110043 PMID:28408883 PMID:33002460 PMID:33010382 PMID:36843289
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