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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:30778
Term: gallic acid
Definition: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
Chemical ID: MESH:D005707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDGallic Acid results in decreased expression of BCL2 proteinPMID:19723098
Bcl2multiple interactionsEXP 6480464CTDGallic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of BCL2 protein]; Resveratrol inhibits the reaction [Gallic Acid results in decreased expression of BCL2 protein]PMID:19723098 PMID:31925992
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDGallic Acid results in decreased expression of BCL2 proteinPMID:22245431
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTDGallic Acid inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]PMID:21420233
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