GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | decreases expression | EXP | | 6480464 | CTD | Sodium Fluoride results in decreased expression of BCL2 mRNA; Sodium Fluoride results in decreased expression of BCL2 protein | PMID:27871895 PMID:29758312 PMID:35172196 PMID:35413380 | Bcl2 | multiple interactions | EXP | | 6480464 | CTD | Hesperidin inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; protocatechuic acid methyl ester inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 protein]; Sodium Fluoride affects the reaction [Gentamicins affects the expression of BCL2 mRNA] | PMID:26779593 PMID:27871895 PMID:29758312 PMID:35413380 | Bcl2 | decreases expression | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | Sodium Fluoride results in decreased expression of BCL2 mRNA; Sodium Fluoride results in decreased expression of BCL2 protein | PMID:23578390 PMID:27871895 PMID:30225638 PMID:30738887 | Bcl2 | decreases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Sodium Fluoride results in decreased expression of BCL2 mRNA | PMID:28962382 | Bcl2 | multiple interactions | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in decreased expression of BCL2 mRNA]; [Sodium Fluoride results in increased abundance of Fluorides] promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 mRNA]; [Sodium Fluoride results in increased abundance of Fluorides] which results in decreased expression of BCL2 mRNA; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA] | PMID:27871895 PMID:35714946 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | [Sodium Fluoride inhibits the reaction [CA2 protein binds to BAD protein]] promotes the reaction [BAD protein binds to BCL2 protein]; Sodium Fluoride promotes the reaction [BAD protein binds to BCL2 protein] | PMID:21708216 | | ||||||||||||||||||||||
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