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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:27812
Term: Se-methyl-L-selenocysteine
Definition: An L-alpha-amino acid compound having methylselanylmethyl as the side-chain.
Chemical ID: MESH:C002979
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDselenomethylselenocysteine results in decreased expression of BCL2 proteinPMID:11396176
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDselenomethylselenocysteine results in decreased expression of BCL2 mRNAPMID:19360359
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 proteinPMID:19360359
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