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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:80883
Term: Ophiopogonin D
Definition: A steroid saponin that has formula C44H70O16.
Chemical ID: MESH:C046996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDophiopogonin D results in decreased expression of BCL2 proteinPMID:35905946
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [ophiopogonin D results in decreased expression of BCL2 protein]PMID:35905946
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