Bp326 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp326 (Blood pressure QTL 326) Rattus norvegicus

Symbol: Bp326
Name: Blood pressure QTL 326
RGD ID: 2303031
Previously known as: region 1
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21311,766,535 - 23,001,904RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01314,279,081 - 26,919,398RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01319,518,130 - 32,069,874RGDRnor5.0
RGSC_v3.4131,084,268 - 13,053,933RGDRGSC3.4
Cross Type: intercross
Strains Crossed: SS.BN-(D13Rat7-D13Rat60)/Mcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Hypotension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Multiple Blood Pressure loci on rat Chromosome 13 attenuate the development of hypertension in the Dahl S Hypertensive rat. Moreno C, etal., Physiol Genomics. 2007 Jun 12;.
Related QTLs

Related QTL Description Reference
Bp327 interacts with RGD:1625678
Bp328 interacts with RGD:1625678


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
69342Serpinb5serpin family B member 5132298555723005756Rat
621308Phlpp1PH domain and leucine rich repeat protein phosphatase 1132230853222530978Rat
2199Bcl2BCL2, apoptosis regulator132268978322853920Rat
1307235RelchRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing132180697221902807Rat
1305438Cdh20cadherin 20132073764021069746Rat
1307775Kdsr3-ketodihydrosphingosine reductase132286211722894118Rat
1305251Rnf152ring finger protein 152132132403921403405Rat
1311346Pignphosphatidylinositol glycan anchor biosynthesis, class N132165909221812932Rat
1310626Zcchc2zinc finger CCHC-type containing 2132211867722193626Rat
1305969Vps4bvacuolar protein sorting 4 homolog B132290710522932200Rat
1561440RGD1561440similar to nemo like kinase131593453615938158Rat
1563614Tnfrsf11aTNF receptor superfamily member 11A132192837021986719Rat
1565194Cntnap5bcontactin associated protein family member 5B131786336718766983Rat
1583413Josd1-ps1Josephin domain containing 1, pseudogene 1131469931614699912Rat
1585944Phb1-ps16prohibitin 1, pseudogene 16131369533213696148Rat
1592077LOC304725similar to contactin associated protein-like 5 isoform 1131185376112864307Rat
1587089LOC679594similar to polyubiquitin131180299811803461Rat
1584807Rps4x-ps11ribosomal protein S4, X-linked, pseudogene 11131534048915341938Rat
1594544Kif13a-ps1kinesin family member 13A, pseudogene 1131601713416021538Rat
1596843Hmgb3-ps2high mobility group box 3, pseudogene 2132060090720601478Rat
1593260Hspd1-ps8heat shock protein family D (Hsp60) member 1, pseudogene 8131404430914046528Rat
1598145Gemin8-ps4gem (nuclear organelle) associated protein 8, pseudogene 4131769333317694256Rat
2318305Ccdc28a-ps1coiled-coil domain containing 28A, pseudogene 1131593217815932833Rat
2321136Smyd3-ps1SET and MYND domain containing 3, pseudogene 1131504460815045633Rat
6487798Fau-ps3FAU ubiquitin like and ribosomal protein S30 fusion, pseudogene 3132162910221629445Rat
6490239Btf3-ps3basic transcription factor 3, pseudogene 3131723827017239523Rat
7529420Eif4a1-ps1eukaryotic translation initiation factor 4A1, pseudogene 1131251196712513501Rat
7498875LOC102547165uncharacterized LOC102547165132105507721068613Rat
7641700LOC102550524uncharacterized LOC102550524132206441822111976Rat
7701520LOC102550337uncharacterized LOC102550337132202801022042859Rat
9091700LOC103691604uncharacterized LOC103691604131531458815381026Rat
9160875LOC103691608uncharacterized LOC103691608132126231621264777Rat
9117769LOC103691598methionine adenosyltransferase 2 subunit beta pseudogene131483603514836975Rat
9400371LOC103691625protein phosphatase 1 regulatory subunit 14B pseudogene131952200919522605Rat
11469342LOC108352516uncharacterized LOC108352516132201820222027872Rat
11457739LOC108352514uncharacterized LOC108352514131690756616931271Rat
11394992LOC108352518uncharacterized LOC108352518132258998722598210Rat
41325179NEWGENE_40933693transfer RNA proline (anticodon GGG)131316820113168282Rat
41181148Gapdh-ps44Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 44132199505421996060Rat
41182474LOC120096227uncharacterized LOC120096227131690459316910352Rat
41289916LOC120096412small nucleolar RNA SNORA17131224084912240975Rat
41072330Ormdl1-ps6ORMDL sphingolipid biosynthesis regulator 1, pseudogene 6131653241816538949Rat
41293470Tp53-ps1tumor protein p53, pseudogene 1131206496212071434Rat
41131179LOC120096229uncharacterized LOC120096229132273222722739137Rat
41165395LOC120096398small nucleolar RNA SNORA17131842296618423097Rat
40995925LOC120096444U6 spliceosomal RNA131586392815864034Rat
41026629Dnajc14-ps1DnaJ heat shock protein family (Hsp40) member C14, pseudogene 1131727147617273698Rat
41316489NEWGENE_40973998transfer RNA histidin (anticodon AUG)132190993821910012Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34076D13Mgh1149131769443617694591Ratregion
35208D13Rat2165131828723718287390Ratregion
36888D13Rat6143132053128920531432Ratregion
36922D13Rat4132131192944911929569Ratregion
36630D13Rat5162131842037818420540Ratregion
36699D13Rat1290132060555520605871Ratregion
34767D13Rat35133131582850015828633Ratregion
35649D13Rat3162132162156721621744Ratregion
35975D13Rat7174131176653511766737Ratregion
39778D13Rat134196131688113216881328Ratregion
40618D13Rat144153131846776218467901Ratregion
39032D13Rat60131132300177923001904Ratregion
39196D13Rat68148131309381813093970Ratregion
40936D13Rat107249131225932012259575Ratregion
60549D6Got8165131296238012962545Ratregion
60500D6Got10290131525702115257303Ratregion
60726D1Mit25149131639167416391823Ratregion
66674D13Mco13180132252526922525438Ratregion
66677D13Mco14250132093231420932792Ratregion
66677D13Mco14250132093255320932792Ratregion
1630306D13Got215168131897659418976762Ratregion
1631200D13Got265152131491750414917656Ratregion
1631215D13Got258161132201440722014568Ratregion
1632298D13Got221194132198790721988098Ratregion
1627719D13Got247190131526151615261706Ratregion
1628857D13Got201166131897659418976760Ratregion
1629574D13Got217113132147543221475545Ratregion
1629858D13Uwm8118132228403822284156Ratregion
1638571D13Got27099132147544521475544Ratregion
1639128D13Got210284131314678113147060Ratregion
1632825D13Got218123132018317620183299Ratregion
1635185D13Got214116132175082621750935Ratregion
1635404D13Got245201132017835020178551Ratregion
1638308D13Got235210132032215620322366Ratregion
1633646D13Got246263131761235317612616Ratregion
1633806D13Got239175132220146222201637Ratregion
5035779PMC16825P1703132285142522852128Ratregion
5036921AU049632137131256475212564891Ratregion
5035544Ranbp10131671995416720426Ratregion
5031350PMC150726P1294132285168322851977Ratregion
5028779RH142296155132285201522852172Ratregion
5031664AU047559241131408482214085059Ratregion
5028939RH142898142131601798316018125Ratregion
5031708AU047414232131305219613052423Ratregion
5031806AU047086145132263428722634432Ratregion
5026732RH133326199132286045922860658Ratregion
5034728BE100511160132286252322862683Ratregion
5033157RH137803174131261941912619593Ratregion
5053735RH142820173132008577520085952Ratregion
5057117AA957791220131727551717275702Ratregion
5055461RH143814197132217697922177182Ratregion
5057257AI555189198132233831422338512Ratregion
5050794RH134262211132210376822103979Ratregion
5044328RH130540180132165965321659833Ratregion
5044792RH130806201132285537522855576Ratregion
5046402RH131732213132273717022737383Ratregion
5048916RH133180203132166206121662264Ratregion
5049086RH133278152132253075822530910Ratregion
5049086RH133278152132253075822530910Ratregion
5071932RH135368203132132511721325320Ratregion
5077272RH139661209132117975521179964Ratregion
5077966RH140064211132165922321659434Ratregion
5077880RH140013218132290713022907348Ratregion
5080154RH141416201132200170822001909Ratregion
5080296RH141498198132132430221324500Ratregion
5073268RH137338197132211883722119034Ratregion
5072162RH136688187132132469621324883Ratregion
5063380BI301796196131703630717036503Ratregion
5067212AU047893284132254927022549554Ratregion
5067310AU047833247132166590521666152Ratregion
5067678AU047601173131759039517590568Ratregion
5067886AU047477186132155792121558107Ratregion
5069060AU046749174132123692621237100Ratregion
5069136AU046701150131906883819068988Ratregion
5065814BE109920169132172474121724910Ratregion
5089243AU049040154131824919918249353Ratregion
5090857AU050007136131982536719825503Ratregion
5503350Nlk-ps1648131593667915937327Ratregion
5503444Trp53329131206951112069840Ratregion
5503244UniSTS:237455213131672044516720662Ratregion
5504614PMC316415P3600132285194422852544Ratregion
5504831ha2188868132175760721758475Ratregion
5500971PMC104155P1268132285142722851695Ratregion
5500991PMC114224P2335132199506921995404Ratregion
5503446UniSTS:461954348132285151422851862Ratregion
5501039PMC125347P1447132285148822851935Ratregion
Position Markers

Flank 1: (D13Rat7)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21311,766,535 - 11,766,737 (+)MAPPER
Rnor_6.01314,279,081 - 14,279,282NCBI
Rnor_5.01319,518,130 - 19,518,331UniSTS
RGSC_v3.4131,084,269 - 1,084,470UniSTS
RGSC_v3.4131,084,268 - 1,084,470RGD
RGSC_v3.1131,084,268 - 1,084,470RGD
Celera1311,796,004 - 11,796,205UniSTS
SHRSP x BN Map131.1799UniSTS
SHRSP x BN Map131.1799RGD
FHH x ACI Map133.68RGD
Flank 2: (D13Rat60)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21323,001,779 - 23,001,904 (+)MAPPER
Rnor_6.01326,919,274 - 26,919,398NCBI
Rnor_5.01332,069,750 - 32,069,874UniSTS
RGSC_v3.41313,053,808 - 13,053,933RGD
RGSC_v3.41313,053,809 - 13,053,933UniSTS
RGSC_v3.11313,053,595 - 13,053,950RGD
Celera1322,859,002 - 22,859,128UniSTS
SHRSP x BN Map133.3799UniSTS
SHRSP x BN Map133.3799RGD
Cytogenetic Map13p13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2303031Bp326Blood pressure QTL 326arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131176653523001904Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131176653532331607Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131176653532331607Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 10-15 for each sex 1625678
qtl_general measurement method: 2 days after the implantation of catheter heart rate, systolic, diastolic and mean arterial pressure were recorded 1625678
qtl_general diet: 8.0% NaCl diet was given at 10 weeks of age, 2 weeks before the catheter were implanted 1625678
qtl_general females showed protection from hypertension 1625678
qtl_map 12.4 Mbp 1625678