Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:16015
Term: L-glutamic acid
Definition: An optically active form of glutamic acid having L-configuration.
Chemical ID: MESH:D018698
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDGlutamic Acid results in decreased expression of BCL2 proteinPMID:32092300 PMID:35028790
Bcl2multiple interactionsEXP 6480464CTD1,3-benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile promotes the reaction [shikonin inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]]; Memantine analog inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; Memantine inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; MKC8866 promotes the reaction [shikonin inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]]; shikonin inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [shikonin inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]]PMID:32092300 PMID:35028790
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDGlutamic Acid results in decreased expression of BCL2 proteinPMID:33617922
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTDdihydroactinidiolide inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]PMID:33617922
Go Back to source page   Continue to Ontology report