Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:78870
Term: sodium nitrite
Definition: An inorganic sodium salt having nitrite as the counterion. Used as a food preservative and antidote to cyanide poisoning.
Chemical ID: MESH:D012977
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDSodium Nitrite results in decreased expression of BCL2 mRNA, Sodium Nitrite results in decreased expression of BCL2 protein

PMID:28000380, PMID:28266762, PMID:28833918
Bcl2multiple interactionsEXP 6480464CTDCarnosine inhibits the reaction [Sodium Nitrite results in decreased expression of BCL2 protein], Quercetin inhibits the reaction [Sodium Nitrite results in decreased expression of BCL2 protein]

PMID:28000380, PMID:28266762
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.