Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:39483
Term: sodium dichromate
Definition: An inorganic sodium salt that has formula Cr2Na2O7.
Chemical ID: MESH:C016104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2affects expressionEXP 6480464CTDsodium bichromate affects the expression of BCL2 mRNAPMID:11960910
Bcl2affects response to substanceISOBCL2 (Homo sapiens)6480464CTDBCL2 protein affects the susceptibility to sodium bichromatePMID:19556603
Bcl2decreases expressionISOBcl2 (Mus musculus)6480464CTDsodium bichromate results in decreased expression of BCL2 proteinPMID:20298709
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDsodium bichromate results in decreased expression of BCL2 proteinPMID:18544562 PMID:19556603
Bcl2increases expressionISOBCL2 (Homo sapiens)6480464CTDsodium bichromate results in increased expression of BCL2 proteinPMID:28624442
Bcl2increases ubiquitinationISOBCL2 (Homo sapiens)6480464CTDsodium bichromate results in increased ubiquitination of BCL2 proteinPMID:18544562
Bcl2multiple interactionsISOBcl2 (Mus musculus)6480464CTDCAT protein inhibits the reaction [sodium bichromate results in decreased expression of BCL2 protein]; TRP53 mutant form inhibits the reaction [sodium bichromate results in decreased expression of BCL2 protein]PMID:20298709
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD6-anilino-5,8-quinolinedione inhibits the reaction [sodium bichromate results in increased ubiquitination of BCL2 protein]; FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of BCL2 protein]; lactacystin inhibits the reaction [sodium bichromate results in decreased expression of BCL2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [sodium bichromate results in decreased expression of BCL2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [sodium bichromate results in increased ubiquitination of BCL2 protein]PMID:18544562 PMID:28624442
Go Back to source page   Continue to Ontology report