Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of MAP kinase activity
go back to main search page
Accession:GO:0043406 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
Synonyms:exact_synonym: positive regulation of mitogen activated protein kinase activity;   up regulation of MAPK activity;   upregulation of MAPK activity
 narrow_synonym: stimulation of MAPK activity


show annotations for term's descendants           Sort by:
positive regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 8:25,439,627...25,507,138
Ensembl chr 8:25,439,627...25,506,943 		JBrowse link
G Adra2a adrenergic receptor, alpha 2a involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413 		JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within IDA (PMID:10330178) MGI PMID:10330178 NCBI chr14:54,804,926...54,815,118
Ensembl chr14:54,804,929...54,815,015 		JBrowse link
G Akap13 A kinase anchor protein 13 involved_in ISO PMID:23716597 UniProt PMID:23716597 RGD:11059588 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357 		JBrowse link
G Cd24a CD24a antigen involved_in ISS
ISO		 (PMID:12496407) UniProt
GO_Central		 PMID:12496407 GO_REF:0000024 GO_REF:0000119 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261 		JBrowse link
G Cd40 CD40 antigen involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:11994468) MGI PMID:11994468 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028 		JBrowse link
G Cripto cripto, EGF-CFC family member acts_upstream_of_or_within ISO (PMID:9013573) MGI PMID:9013573 NCBI chr 9:110,768,676...110,775,226
Ensembl chr 9:110,768,671...110,775,226 		JBrowse link
G Csk c-src tyrosine kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914 		JBrowse link
G Diras1 DIRAS family, GTP-binding RAS-like 1 NOT|involved_in ISO (PMID:12194967) UniProt PMID:12194967 NCBI chr10:80,855,423...80,862,038
Ensembl chr10:80,855,423...80,861,496 		JBrowse link
G Diras2 DIRAS family, GTP-binding RAS-like 2 NOT|involved_in ISO (PMID:12194967) UniProt PMID:12194967 NCBI chr13:52,658,411...52,685,390
Ensembl chr13:52,658,416...52,685,315 		JBrowse link
G Drd4 dopamine receptor D4 acts_upstream_of
involved_in		 ISO GO_Central GO_REF:0000119 NCBI chr 7:140,871,931...140,874,868
Ensembl chr 7:140,871,919...140,876,377 		JBrowse link
G Edn1 endothelin 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Edn3 endothelin 3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:174,602,412...174,625,835
Ensembl chr 2:174,602,412...174,625,835 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 acts_upstream_of_or_within ISO GO_Central GO_REF:0000119 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide acts_upstream_of_or_within IDA (PMID:9000133) MGI PMID:9000133 NCBI chr 1:173,048,836...173,054,799
Ensembl chr 1:173,048,851...173,054,781 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in ISO GO_Central GO_REF:0000119 NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Gab1 growth factor receptor bound protein 2-associated protein 1 acts_upstream_of_or_within IMP (PMID:12808090) MGI PMID:12808090 NCBI chr 8:81,491,060...81,607,151
Ensembl chr 8:81,491,063...81,607,148 		JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) AgBase PMID:24313324 NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731 		JBrowse link
G Ghr growth hormone receptor acts_upstream_of ISO PMID:8063815 BHF-UCL PMID:8063815 RGD:8553732 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within IMP (PMID:26375174) MGI PMID:26375174 NCBI chr 1:125,604,725...125,804,132
Ensembl chr 1:125,604,732...125,801,599 		JBrowse link
G Hras Harvey rat sarcoma virus oncogene involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918 		JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO RGD PMID:15087293 RGD:1624373 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934 		JBrowse link
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) acts_upstream_of_or_within IDA (PMID:9000133) MGI PMID:9000133
G Il1b interleukin 1 beta acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il34 interleukin 34 acts_upstream_of_or_within ISO GO_Central GO_REF:0000119 NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556 		JBrowse link
G Ilk integrin linked kinase ISO inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132 		JBrowse link
G Insr insulin receptor acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:23987506 RGD:11049533 NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in IMP (PMID:17379480) BHF-UCL PMID:17379480 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase acts_upstream_of_or_within IGI (PMID:10620616) MGI PMID:10620616 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kitl kit ligand acts_upstream_of_or_within IGI (PMID:10620616) MGI PMID:10620616 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog ISO RGD PMID:10969813 RGD:1600497 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Maged1 MAGE family member D1 involved_in IMP (PMID:19268530) UniProt PMID:19268530 NCBI chr  X:93,579,080...93,585,631
Ensembl chr  X:93,579,080...93,585,749 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 acts_upstream_of_or_within IDA (PMID:14744933) MGI PMID:14744933 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) involved_in IDA (PMID:10364264) BHF-UCL PMID:10364264 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:107,784,057...107,797,582
Ensembl chr 9:107,784,072...107,797,582 		JBrowse link
G Nek10 NIMA (never in mitosis gene a)- related kinase 10 involved_in ISO GO_Central GO_REF:0000119 NCBI chr14:7,457,704...7,666,183
Ensembl chr14:7,457,704...7,666,348 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in IMP (PMID:17942966) UniProt PMID:17942966 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873 		JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 acts_upstream_of_or_within IMP (PMID:17306762) MGI PMID:17306762 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 3:75,423,797...75,464,159
Ensembl chr 3:75,423,797...75,464,163 		JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific involved_in IMP (PMID:19127022) BHF-UCL PMID:19127022 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023 		JBrowse link
G Pdgfa platelet derived growth factor, alpha involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide involved_in IDA (PMID:17942966) UniProt PMID:17942966 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma involved_in ISO GO_Central GO_REF:0000119 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:68,322,951...68,388,675
Ensembl chr11:68,322,947...68,388,675 		JBrowse link
G Pik3r6 phosphoinositide-3-kinase regulatory subunit 5 involved_in IDA (PMID:19906996) UniProt PMID:19906996 NCBI chr11:68,393,845...68,443,524
Ensembl chr11:68,393,845...68,443,524 		JBrowse link
G Pla2g1b phospholipase A2, group IB, pancreas acts_upstream_of ISO (PMID:15528384), (PMID:16005851) BHF-UCL PMID:15528384 PMID:16005851 NCBI chr 5:115,604,201...115,612,781
Ensembl chr 5:115,604,321...115,612,781 		JBrowse link
G Prkcd protein kinase C, delta ISO RGD PMID:16935468 RGD:1642549 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within IMP (PMID:15896720) MGI PMID:15896720 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IMP (PMID:9254656) MGI PMID:9254656 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr16:71,824,406...72,844,379
Ensembl chr16:72,105,194...72,842,983 		JBrowse link
G Src Rous sarcoma oncogene ISO RGD PMID:11941412 RGD:150523765 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO RGD PMID:21607062 RGD:5508182 NCBI chr15:80,017,333...80,045,908
Ensembl chr15:80,017,328...80,045,908 		JBrowse link
G Tenm1 teneurin transmembrane protein 1 involved_in IDA (PMID:22698694) UniProt PMID:22698694 NCBI chr  X:41,616,743...42,518,045
Ensembl chr  X:41,616,743...42,518,003 		JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of IMP (PMID:20051628) BHF-UCL PMID:20051628 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of		 ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 involved_in ISO GO_Central GO_REF:0000119 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483 		JBrowse link
G Tpd52l1 tumor protein D52-like 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:31,208,369...31,321,989
Ensembl chr10:31,208,372...31,321,954 		JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor acts_upstream_of_or_within IMP (PMID:18323529) MGI PMID:18323529 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Arhgef5 Rho guanine nucleotide exchange factor 5 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 6:43,242,578...43,266,250
Ensembl chr 6:43,242,516...43,266,254 		JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within IMP
IDA
ISO		 (PMID:12878610), (PMID:15579909)
(PMID:17681137)		 MGI PMID:12878610 PMID:15579909 PMID:17681137 NCBI chr17:26,350,294...26,414,784
Ensembl chr17:26,357,662...26,414,785 		JBrowse link
G Bcl10 B cell leukemia/lymphoma 10 NOT|acts_upstream_of_or_within ISO (PMID:10187771) MGI PMID:10187771 NCBI chr 3:145,630,017...145,640,121
Ensembl chr 3:145,628,559...145,640,111 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 acts_upstream_of IDA (PMID:16027136) BHF-UCL PMID:16027136 NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 acts_upstream_of IC (PMID:16027136) BHF-UCL PMID:16027136 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Dab2ip disabled 2 interacting protein involved_in IMP
ISO		 (PMID:18281285) BHF-UCL
GO_Central		 PMID:18281285 GO_REF:0000119 NCBI chr 2:35,448,285...35,621,006
Ensembl chr 2:35,448,278...35,621,006 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in IDA (PMID:11959862) BHF-UCL PMID:11959862 NCBI chr 2:80,447,558...80,462,005
Ensembl chr 2:80,447,389...80,462,705 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in IDA
ISO		 (PMID:10829020) BHF-UCL
GO_Central		 PMID:10829020 GO_REF:0000119 NCBI chr11:69,891,418...69,900,935
Ensembl chr11:69,891,421...69,903,127 		JBrowse link
G Edn1 endothelin 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Epha4 Eph receptor A4 involved_in IDA (PMID:10523642) BHF-UCL PMID:10523642 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 involved_in IMP
ISO		 (PMID:10650002) ParkinsonsUK-UCL
GO_Central		 PMID:10650002 GO_REF:0000119 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signalling 2 involved_in IDA (PMID:10650002) ParkinsonsUK-UCL PMID:10650002 NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430 		JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide acts_upstream_of_or_within IDA (PMID:9000133) MGI PMID:9000133 NCBI chr 1:173,048,836...173,054,799
Ensembl chr 1:173,048,851...173,054,781 		JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 acts_upstream_of_or_within IGI (PMID:18838382) MGI PMID:18838382 NCBI chr17:29,579,878...29,598,509
Ensembl chr17:29,579,888...29,598,635 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 acts_upstream_of_or_within ISO (PMID:9668039) MGI PMID:9668039 NCBI chr16:16,234,774...16,418,400
Ensembl chr16:16,234,781...16,418,413 		JBrowse link
G Fzd4 frizzled class receptor 4 acts_upstream_of_or_within IGI (PMID:15195140) MGI PMID:15195140 NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342 		JBrowse link
G Fzd5 frizzled class receptor 5 acts_upstream_of_or_within IDA (PMID:15195140) MGI PMID:15195140 NCBI chr 1:64,769,717...64,776,907
Ensembl chr 1:64,769,717...64,776,910 		JBrowse link
G Fzd8 frizzled class receptor 8 acts_upstream_of_or_within IDA (PMID:15195140) MGI PMID:15195140 NCBI chr18:9,212,856...9,216,201
Ensembl chr18:9,212,163...9,218,136 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) acts_upstream_of_or_within IDA (PMID:9000133) MGI PMID:9000133
G Il1b interleukin 1 beta ISO RGD PMID:12667655 RGD:1626684 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in IMP (PMID:17379480) BHF-UCL PMID:17379480 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524 		JBrowse link
G Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 acts_upstream_of_or_within IGI (PMID:15195140) MGI PMID:15195140 NCBI chr 3:103,920,575...104,127,722
Ensembl chr 3:103,920,575...104,127,690 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 acts_upstream_of_or_within ISO (PMID:17681137) MGI PMID:17681137 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 involved_in IDA (PMID:11959862) BHF-UCL PMID:11959862 NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 involved_in ISO
IDA		 (PMID:10523642) RGD
BHF-UCL		 PMID:9110999 PMID:10523642 RGD:2293488 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527 		JBrowse link
G Map3k10 mitogen-activated protein kinase kinase kinase 10 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:27,355,800...27,374,059
Ensembl chr 7:27,355,800...27,374,023 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:5,738,764...5,752,893
Ensembl chr19:5,738,770...5,752,893 		JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 involved_in IMP (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chr15:102,406,079...102,425,311
Ensembl chr15:102,406,081...102,425,499 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in IMP (PMID:27511108) ARUK-UCL PMID:27511108 NCBI chr16:21,643,923...21,752,189
Ensembl chr16:21,613,096...21,752,189 		JBrowse link
G Map3k4 mitogen-activated protein kinase kinase kinase 4 acts_upstream_of_or_within
involved_in		 IMP
IDA
ISO		 (PMID:12878610)
(PMID:16157600)		 MGI
UniProt
GO_Central		 PMID:12878610 PMID:16157600 GO_REF:0000119 NCBI chr17:12,446,508...12,537,683
Ensembl chr17:12,446,508...12,537,683 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO RGD
GO_Central		 PMID:20716917 GO_REF:0000119 RGD:10412640 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:6,391,023...6,405,649
Ensembl chr19:6,391,165...6,405,645 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 acts_upstream_of_or_within
involved_in		 IDA (PMID:15767678)
(PMID:10523642)		 MGI
BHF-UCL		 PMID:10523642 PMID:15767678 NCBI chr17:25,116,480...25,155,951
Ensembl chr17:25,111,127...25,155,942 		JBrowse link
G Mir92-1 microRNA 92-1 involved_in ISO (PMID:24332650) BHF-UCL PMID:24332650 NCBI chr14:115,281,859...115,281,938
Ensembl chr14:115,281,859...115,281,938 		JBrowse link
G Mir92-2 microRNA 92-2 involved_in ISO (PMID:24332650) BHF-UCL PMID:24332650 NCBI chr  X:51,830,715...51,830,805
Ensembl chr  X:51,830,715...51,830,805 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588 		JBrowse link
G Ptk2b PTK2 protein tyrosine kinase 2 beta ISO RGD PMID:15226266 RGD:1642623 NCBI chr14:66,390,706...66,518,549
Ensembl chr14:66,390,706...66,518,501 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 acts_upstream_of IMP (PMID:15465829) ParkinsonsUK-UCL PMID:15465829 NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr13:53,263,353...53,440,160
Ensembl chr13:53,263,348...53,440,160 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:99,127,103...99,132,916
Ensembl chr 7:99,127,103...99,132,945 		JBrowse link
G Sash1 SAM and SH3 domain containing 1 acts_upstream_of_or_within ISO (PMID:23776175) MGI PMID:23776175 NCBI chr10:8,597,981...8,821,290
Ensembl chr10:8,597,983...8,761,814 		JBrowse link
G Syk spleen tyrosine kinase acts_upstream_of_or_within IMP (PMID:9000133) MGI PMID:9000133 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:117,258,180...117,413,283
Ensembl chr 5:117,258,194...117,413,284 		JBrowse link
G Tiam1 T cell lymphoma invasion and metastasis 1 ISO RGD PMID:16203995 RGD:10043312 NCBI chr16:89,583,999...89,942,488
Ensembl chr16:89,583,999...89,940,657 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein acts_upstream_of_or_within ISO (PMID:11544529) MGI PMID:11544529 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tlr6 toll-like receptor 6 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 5:65,109,373...65,128,387
Ensembl chr 5:65,109,374...65,117,440 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709 		JBrowse link
G Traf2 TNF receptor-associated factor 2 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952 		JBrowse link
G Traf6 TNF receptor-associated factor 6 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014 		JBrowse link
G Vangl2 VANGL planar cell polarity 2 acts_upstream_of_or_within IGI (PMID:15195140) MGI PMID:15195140 NCBI chr 1:171,828,527...171,856,532
Ensembl chr 1:171,828,527...171,856,011 		JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A acts_upstream_of_or_within IMP
ISO
IDA		 (PMID:19300477) MGI
GO_Central		 PMID:19300477 GO_REF:0000119 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within IMP (PMID:17644613) MGI PMID:17644613 NCBI chr 2:44,873,523...45,007,378
Ensembl chr 2:44,873,644...45,007,407 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      signal transduction 6912
        positive regulation of signal transduction 1819
          positive regulation of intracellular signal transduction 1296
            positive regulation of MAPK cascade 575
              positive regulation of MAP kinase activity 123
                positive regulation of JUN kinase activity 56
Path 2
Term Annotations click to browse term
  biological_process 28635
    biological regulation 13440
      regulation of biological process 13004
        regulation of cellular process 12619
          regulation of metabolic process 7028
            regulation of macromolecule metabolic process 6485
              regulation of protein metabolic process 2332
                regulation of protein modification process 1290
                  regulation of protein phosphorylation 1012
                    regulation of protein kinase activity 555
                      regulation of protein serine/threonine kinase activity 309
                        regulation of MAP kinase activity 190
                          positive regulation of MAP kinase activity 123
                            positive regulation of JUN kinase activity 56
paths to the root