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Gene: Bcl10 (B cell leukemia/lymphoma 10) Mus musculus
Symbol: Bcl10
Name: B cell leukemia/lymphoma 10
Description: Predicted to contribute to kinase activator activity. Involved in several processes, including lymphocyte apoptotic process; positive regulation of NF-kappaB transcription factor activity; and positive regulation of apoptotic process. Localizes to the cytosol; immunological synapse; and membrane raft. Human ortholog(s) of this gene implicated in MALT lymphoma; malignant mesothelioma; non-Hodgkin lymphoma; and primary immunodeficiency disease. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; sensory organ; and vibrissa follicle. Orthologous to human BCL10 (BCL10 immune signaling adaptor); PARTICIPATES IN nuclear factor kappa B signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; INTERACTS WITH 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI132454; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL-10; c-E10; C81403; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; CARMEN; cCARMEN; cE10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; cellular-E10; CIPER; CLAP; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; ME10
Homo sapiens (human) : BCL10 (BCL10 immune signaling adaptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bcl10 (BCL10, immune signaling adaptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl10 (BCL10 immune signaling adaptor)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL10 (BCL10 immune signaling adaptor)
Canis lupus familiaris (dog) : BCL10 (BCL10 immune signaling adaptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl10 (BCL10 immune signaling adaptor)
Sus scrofa (pig) : BCL10 (BCL10 immune signaling adaptor)
Chlorocebus sabaeus (green monkey) : BCL10 (BCL10 immune signaling adaptor)
Heterocephalus glaber (naked mole-rat) : Bcl10 (BCL10 immune signaling adaptor)
more info ...
Related Pseudogenes: Gm6141  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl3145,922,804 - 145,934,356 (+)Ensembl
GRCm383145,924,262 - 145,934,366 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373145,587,342 - 145,597,247 (+)NCBIGRCm37mm9NCBIm37
MGSCv363145,861,764 - 145,871,669 (+)NCBImm8
Celera3152,377,785 - 152,387,900 (+)NCBICelera
Cytogenetic Map3 H2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Bcl10
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733736
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.