Fgf18 (fibroblast growth factor 18) - Rat Genome Database

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Gene: Fgf18 (fibroblast growth factor 18) Mus musculus
Analyze
Symbol: Fgf18
Name: fibroblast growth factor 18
RGD ID: 737084
MGI Page MGI
Description: Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Acts upstream of or within several processes, including positive regulation of chondrocyte differentiation; positive regulation of signal transduction; and skeletal system development. Predicted to be located in nucleolus. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; musculoskeletal system; and sensory organ. Orthologous to human FGF18 (fibroblast growth factor 18).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D130055P09Rik; FGF-18; Fgf6a; fibroblast growth factor 6a; zFGF5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,066,970 - 33,097,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,067,430 - 33,097,400 (-)EnsemblGRCm39 Ensembl
GRCm381133,116,970 - 33,147,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,117,430 - 33,147,400 (-)EnsemblGRCm38mm10GRCm38
MGSCv371133,017,430 - 33,047,400 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361133,017,430 - 33,047,400 (-)NCBIMGSCv36mm8
Celera1135,529,642 - 35,559,689 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-taxifolin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-tert-butylhydroquinone  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3-methylcholanthrene  (EXP)
3-Nitrobenzanthrone  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chloroprene  (EXP)
chlorpyrifos  (ISO)
chondroitin sulfate  (EXP)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dermatan sulfate  (EXP)
dextran sulfate  (EXP)
diethyl malate  (EXP)
diquat  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
fluoranthene  (EXP)
fulvestrant  (EXP)
Glutathione ethyl ester  (EXP)
lead diacetate  (EXP)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel atom  (ISO)
nitrofen  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ochratoxin A  (ISO)
panobinostat  (ISO)
pentanal  (ISO)
phenylephrine  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axial skeleton morphology  (IAGP)
abnormal coat appearance  (IAGP)
abnormal cranial suture morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal fibula morphology  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair cycle anagen phase  (IAGP)
abnormal hair cycle telogen phase  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal lung development  (IAGP)
abnormal lung saccule morphology  (IAGP)
abnormal lung vasculature morphology  (IAGP)
abnormal metatarsal bone morphology  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal osteoblast differentiation  (IAGP)
abnormal respiratory mechanics  (IAGP)
abnormal rib morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal tail morphology  (IAGP)
bowed radius  (IAGP)
bowed tibia  (IAGP)
cleft secondary palate  (IAGP)
cyanosis  (IAGP)
decreased birth body size  (IAGP)
decreased body weight  (IAGP)
delayed bone ossification  (IAGP)
delayed cranial suture closure  (IAGP)
delayed endochondral bone ossification  (IAGP)
delayed intramembranous bone ossification  (IAGP)
failure of palatal shelf elevation  (IAGP)
increased long bone epiphyseal plate size  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
kyphosis  (IAGP)
maxilla hypoplasia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
short radius  (IAGP)
short tibia  (IAGP)
short ulna  (IAGP)
small lung  (IAGP)
small lung lobe  (IAGP)
small neurocranium  (IAGP)
small thoracic cavity  (IAGP)
thick lung-associated mesenchyme  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Structure and expression of the mRNA encoding a novel fibroblast growth factor, FGF-18. Ohbayashi N, etal., J Biol Chem 1998 Jul 17;273(29):18161-4.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9651520   PMID:9742123   PMID:10349636   PMID:10499586   PMID:10704889   PMID:10751172   PMID:10769235   PMID:10906450   PMID:10960782   PMID:11042159   PMID:11076861   PMID:11152636  
PMID:11165488   PMID:11217851   PMID:11262239   PMID:11276432   PMID:11500373   PMID:11741978   PMID:11900978   PMID:11927601   PMID:11937493   PMID:11937494   PMID:12666204   PMID:12736208  
PMID:14517998   PMID:14602678   PMID:14610273   PMID:14681479   PMID:15252029   PMID:15336546   PMID:15371327   PMID:15470137   PMID:15731404   PMID:15781473   PMID:15963767   PMID:16123981  
PMID:16141072   PMID:16141073   PMID:16267092   PMID:16319118   PMID:16470835   PMID:16602821   PMID:16782087   PMID:16818445   PMID:17014841   PMID:17050674   PMID:17090159   PMID:17128416  
PMID:17150206   PMID:17158875   PMID:17488195   PMID:17959802   PMID:18058912   PMID:18286540   PMID:18653561   PMID:18832069   PMID:18835578   PMID:19000669   PMID:19217897   PMID:19218784  
PMID:19358209   PMID:19539783   PMID:19544582   PMID:19581591   PMID:19607792   PMID:19793884   PMID:19906842   PMID:20023171   PMID:20034106   PMID:20040496   PMID:20348033   PMID:20432451  
PMID:20472108   PMID:21087601   PMID:21223962   PMID:21267068   PMID:21368122   PMID:21457097   PMID:21571225   PMID:21873635   PMID:21876757   PMID:21878612   PMID:22297635   PMID:22366163  
PMID:22632802   PMID:22682244   PMID:23322300   PMID:23565059   PMID:23643382   PMID:23751042   PMID:23804023   PMID:23946441   PMID:24012369   PMID:24198358   PMID:24284205   PMID:24909139  
PMID:24952961   PMID:24971735   PMID:25953896   PMID:26441343   PMID:26453795   PMID:26566904   PMID:26595272   PMID:26656997   PMID:26745863   PMID:26748348   PMID:26794256   PMID:27018594  
PMID:27180663   PMID:28027321   PMID:28729444   PMID:28923684   PMID:29184203   PMID:29323161   PMID:31290205   PMID:31862844   PMID:32040930   PMID:32907848   PMID:33034111   PMID:33080014  
PMID:33469032   PMID:33580754   PMID:33629318   PMID:33898467   PMID:34091985   PMID:34321999   PMID:34707292   PMID:34929174   PMID:35020897   PMID:35514236   PMID:36521641   PMID:36542062  
PMID:36685938   PMID:36745673   PMID:37777507   PMID:37813881   PMID:38419044  


Genomics

Comparative Map Data
Fgf18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,066,970 - 33,097,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,067,430 - 33,097,400 (-)EnsemblGRCm39 Ensembl
GRCm381133,116,970 - 33,147,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,117,430 - 33,147,400 (-)EnsemblGRCm38mm10GRCm38
MGSCv371133,017,430 - 33,047,400 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361133,017,430 - 33,047,400 (-)NCBIMGSCv36mm8
Celera1135,529,642 - 35,559,689 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.21NCBI
FGF18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,419,647 - 171,457,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,419,647 - 171,457,626 (+)EnsemblGRCh38hg38GRCh38
GRCh375170,846,651 - 170,884,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365170,779,272 - 170,816,781 (+)NCBINCBI36Build 36hg18NCBI36
Build 345170,779,271 - 170,816,781NCBI
Celera5166,879,014 - 166,916,982 (+)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5165,944,447 - 165,981,862 (+)NCBIHuRef
CHM1_15170,279,191 - 170,317,159 (+)NCBICHM1_1
T2T-CHM13v2.05171,959,977 - 171,997,979 (+)NCBIT2T-CHM13v2.0
Fgf18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81018,210,240 - 18,241,929 (-)NCBIGRCr8
mRatBN7.21017,706,011 - 17,737,702 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,706,174 - 17,736,818 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1022,455,024 - 22,484,592 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,943,626 - 21,973,192 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01017,432,271 - 17,461,845 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,047,109 - 18,082,290 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,047,109 - 18,063,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,932,880 - 17,967,318 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1017,348,236 - 17,383,370 (-)NCBICelera
Cytogenetic Map10q12NCBI
Fgf18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,225,459 - 24,260,092 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540824,225,459 - 24,260,057 (+)NCBIChiLan1.0ChiLan1.0
FGF18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,553,461 - 166,591,129 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15164,693,000 - 164,730,916 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05166,765,061 - 166,802,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FGF18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,714,891 - 40,748,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,715,060 - 40,748,518 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,660,286 - 40,697,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0441,089,249 - 41,126,052 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl441,091,859 - 41,126,139 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,904,218 - 40,941,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0441,094,435 - 41,131,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,604,558 - 41,641,375 (-)NCBIUU_Cfam_GSD_1.0
Fgf18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,954,910 - 94,983,832 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,677,237 - 3,706,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,677,661 - 3,706,511 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,725,356 - 52,759,791 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11652,724,867 - 52,760,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,920,916 - 56,956,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12373,584,223 - 73,620,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2373,584,766 - 73,620,069 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660345,019,198 - 5,060,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473318,599,557 - 18,633,016 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473318,599,186 - 18,633,065 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fgf18
834 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:232
Count of miRNA genes:108
Interacting mature miRNAs:108
Transcripts:ENSMUST00000020507, ENSMUST00000109363
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300607Tnbs2_mtri-nitrobenzene sulfonic acid susceptible 2 (mouse)Not determined112489805235126680Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse

Markers in Region
Fgf18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371133,017,475 - 33,017,816UniSTSGRCm37
MGSCv371133,017,485 - 33,017,603UniSTSGRCm37
Celera1135,529,687 - 35,530,028UniSTS
Celera1135,529,697 - 35,529,815UniSTS
Cytogenetic Map11A4UniSTS
cM Map11 UniSTS
AF075291  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381133,117,492 - 33,117,631UniSTSGRCm38
MGSCv371133,017,492 - 33,017,631UniSTSGRCm37
Celera1135,529,704 - 35,529,843UniSTS
Cytogenetic Map11A4UniSTS
Whitehead/MRC_RH11495.69UniSTS
Fgf18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381133,117,485 - 33,117,603UniSTSGRCm38
MGSCv371133,017,485 - 33,017,603UniSTSGRCm37
Celera1135,529,697 - 35,529,815UniSTS
Cytogenetic Map11A4UniSTS
Fgf18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381133,117,475 - 33,117,816UniSTSGRCm38
MGSCv371133,017,475 - 33,017,816UniSTSGRCm37
Celera1135,529,687 - 35,530,028UniSTS
Cytogenetic Map11A4UniSTS
cM Map11 UniSTS
Fgf18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A4UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000020507   ⟹   ENSMUSP00000020507
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1133,067,430 - 33,097,400 (-)Ensembl
GRCm38.p6 Ensembl1133,117,430 - 33,147,400 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109363   ⟹   ENSMUSP00000104987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1133,067,430 - 33,096,795 (-)Ensembl
GRCm38.p6 Ensembl1133,117,430 - 33,146,795 (-)Ensembl
RefSeq Acc Id: NM_008005   ⟹   NP_032031
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391133,066,970 - 33,097,400 (-)NCBI
GRCm381133,116,970 - 33,147,400 (-)NCBI
MGSCv371133,017,430 - 33,047,400 (-)RGD
Celera1135,529,182 - 35,559,689 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_102395
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391133,066,970 - 33,097,400 (-)NCBI
GRCm381133,116,970 - 33,147,400 (-)NCBI
Celera1135,529,182 - 35,559,689 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032031   ⟸   NM_008005
- Peptide Label: precursor
- UniProtKB: O89101 (UniProtKB/Swiss-Prot),   A0A7U3JW51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020507   ⟸   ENSMUST00000020507
RefSeq Acc Id: ENSMUSP00000104987   ⟸   ENSMUST00000109363

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O89101-F1-model_v2 AlphaFold O89101 1-207 view protein structure

Promoters
RGD ID:6820876
Promoter ID:MM_KWN:6900
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   ES_Cell,   Lung
Transcripts:ENSMUST00000109363,   OTTMUST00000012019
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361133,048,121 - 33,048,621 (-)MPROMDB
RGD ID:8674258
Promoter ID:EPDNEW_M15159
Type:multiple initiation site
Name:Fgf18_1
Description:Mus musculus fibroblast growth factor 18 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381133,147,388 - 33,147,448EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1277980 AgrOrtholog
Ensembl Genes ENSMUSG00000057967 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020507 ENTREZGENE
  ENSMUST00000020507.8 UniProtKB/Swiss-Prot
  ENSMUST00000109363.8 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14172 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1277980 ENTREZGENE
NCBI Gene 14172 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11486:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fgf18 PhenoGen
PRINTS IL1HBGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A7U3JW51 ENTREZGENE, UniProtKB/TrEMBL
  FGF18_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5SQB3_MOUSE UniProtKB/TrEMBL