Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and retina. Used to study dextro-looped transposition of the great arteries 1. Orthologous to human DVL2 (dishevelled segment polarity protein 2); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DVL2 mRNA, AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DVL2 mRNA]
[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of DVL2 protein modified form
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DVL2 mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DVL2 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DVL2 mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DVL2 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DVL2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DVL2 mRNA
boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of DVL2 mRNA]
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DVL2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DVL2 mRNA
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 mRNA], WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 protein]