Dvl2 (dishevelled segment polarity protein 2) - Rat Genome Database
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Gene: Dvl2 (dishevelled segment polarity protein 2) Mus musculus
Analyze
Symbol: Dvl2
Name: dishevelled segment polarity protein 2
RGD ID: 1320220
MGI Page MGI
Description: Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and retina. Used to study dextro-looped transposition of the great arteries 1. Orthologous to human DVL2 (dishevelled segment polarity protein 2); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dishevelled 2, dsh homolog; dishevelled-2; DSH homolog 2; segment polarity protein dishevelled homolog DVL-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,891,418 - 69,900,935 (+)NCBIGRCm39mm39
GRCm39 Ensembl1169,891,421 - 69,903,127 (+)Ensembl
GRCm381170,000,592 - 70,010,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,000,595 - 70,012,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,814,128 - 69,823,611 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,816,821 - 69,826,304 (+)NCBImm8
Celera1177,548,436 - 77,558,061 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cardiac outflow tract development  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal cochlear inner hair cell morphology  (IAGP)
abnormal embryo development  (IAGP)
abnormal head morphology  (IAGP)
abnormal heart looping  (IAGP)
abnormal heart shape  (IAGP)
abnormal notochord morphology  (IAGP)
abnormal organ of Corti morphology  (IAGP)
abnormal orientation of cochlear hair cell stereociliary bundles  (IAGP)
abnormal orientation of outer hair cell stereociliary bundles  (IAGP)
abnormal rib morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal xiphoid process morphology  (IAGP)
absent tail  (IAGP)
caudal body truncation  (IAGP)
craniorachischisis  (IAGP)
cyanosis  (IAGP)
double outlet right ventricle  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged floor plate  (IAGP)
exencephaly  (IAGP)
herniated abdominal wall  (IAGP)
increased cochlear hair cell number  (IAGP)
kinked tail  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
open neural tube  (IAGP)
pericardial effusion  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistent truncus arteriosis  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
rib bifurcation  (IAGP)
rib fusion  (IAGP)
scoliosis  (IAGP)
short rostral-caudal axis  (IAGP)
short snout  (IAGP)
short tail  (IAGP)
small heart  (IAGP)
transposition of great arteries  (IAGP)
ventricular septal defect  (IAGP)
vestigial tail  (IAGP)
References

Additional References at PubMed
PMID:8662242   PMID:8856345   PMID:8887313   PMID:8889548   PMID:8973355   PMID:9680378   PMID:10049570   PMID:10330403   PMID:10349636   PMID:10409711   PMID:10829020   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:12165471   PMID:12384700   PMID:12421720   PMID:12464179   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12805222   PMID:12904583   PMID:14976138  
PMID:15142957   PMID:15143170   PMID:15226823   PMID:15306695   PMID:15454084   PMID:15456783   PMID:15509575   PMID:15579909   PMID:15637299   PMID:15728389   PMID:15782199   PMID:15852005  
PMID:16116426   PMID:16141072   PMID:16141073   PMID:16487141   PMID:16571627   PMID:16602821   PMID:17005174   PMID:17032765   PMID:17199046   PMID:17244647   PMID:17529994   PMID:17592114  
PMID:17606995   PMID:18077588   PMID:18093802   PMID:18162551   PMID:18351662   PMID:18351675   PMID:18606138   PMID:18701545   PMID:18772438   PMID:18775957   PMID:18799693   PMID:18824165  
PMID:19008950   PMID:19300477   PMID:19379695   PMID:19439496   PMID:19465938   PMID:19515997   PMID:19666828   PMID:19701191   PMID:19802005   PMID:19920076   PMID:20098415   PMID:20145239  
PMID:20457807   PMID:20534871   PMID:20663899   PMID:20802536   PMID:20947020   PMID:20970343   PMID:21092292   PMID:21177343   PMID:21189423   PMID:21267068   PMID:21364967   PMID:21373749  
PMID:21691068   PMID:21718540   PMID:21752934   PMID:21873635   PMID:21880741   PMID:21969016   PMID:22166206   PMID:22343533   PMID:22357932   PMID:22560610   PMID:22609948   PMID:22632972  
PMID:22771245   PMID:22826439   PMID:22841628   PMID:23109420   PMID:23122850   PMID:23146885   PMID:23177622   PMID:23190887   PMID:23209302   PMID:23353182   PMID:23371553   PMID:23437169  
PMID:23469192   PMID:23533177   PMID:23580654   PMID:24135232   PMID:24161848   PMID:24284205   PMID:24302887   PMID:24852369   PMID:24952961   PMID:25043421   PMID:25073924   PMID:25145929  
PMID:25190059   PMID:25296022   PMID:25558878   PMID:25596276   PMID:25678599   PMID:25823377   PMID:25825496   PMID:25871009   PMID:26989192   PMID:27582005   PMID:28650466   PMID:28671696  
PMID:28746879   PMID:29229865   PMID:29675451   PMID:30022023   PMID:30254141   PMID:30510196   PMID:31073040   PMID:31623157   PMID:32253237   PMID:32511952   PMID:32579954   PMID:32907846  
PMID:33141892  


Genomics

Comparative Map Data
Dvl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,891,418 - 69,900,935 (+)NCBIGRCm39mm39
GRCm39 Ensembl1169,891,421 - 69,903,127 (+)Ensembl
GRCm381170,000,592 - 70,010,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,000,595 - 70,012,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,814,128 - 69,823,611 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,816,821 - 69,826,304 (+)NCBImm8
Celera1177,548,436 - 77,558,061 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
DVL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,225,342 - 7,234,517 (-)EnsemblGRCh38hg38GRCh38
GRCh38177,225,341 - 7,234,544 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,128,661 - 7,137,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,069,385 - 7,078,587 (-)NCBINCBI36hg18NCBI36
Build 34177,069,384 - 7,078,587NCBI
Celera177,153,295 - 7,162,512 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,020,651 - 7,029,658 (-)NCBIHuRef
CHM1_1177,137,409 - 7,146,611 (-)NCBICHM1_1
Dvl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,723,356 - 54,732,823 (+)NCBI
Rnor_6.0 Ensembl1056,610,051 - 56,619,269 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01056,609,810 - 56,619,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,354,931 - 56,364,388 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1053,877,195 - 53,886,407 (+)NCBICelera
Cytogenetic Map10q24NCBI
Dvl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,675,912 - 9,683,996 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,675,912 - 9,683,996 (+)NCBIChiLan1.0ChiLan1.0
DVL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,242,493 - 7,251,572 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,242,493 - 7,251,571 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,255,241 - 7,264,452 (-)NCBIMhudiblu_PPA_v0panPan3
DVL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl532,194,313 - 32,201,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1532,194,326 - 32,201,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dvl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936595520,299 - 528,361 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DVL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,579,765 - 52,590,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,581,687 - 52,590,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,857,220 - 139,865,809 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DVL2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,599,056 - 6,608,613 (-)NCBI
ChlSab1.1 Ensembl166,599,579 - 6,608,544 (-)Ensembl
Dvl2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247869,843,580 - 9,851,538 (-)NCBI

Position Markers
Dvl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,008,424 - 70,009,916UniSTSGRCm38
MGSCv371169,823,390 - 69,823,518UniSTSGRCm37
MGSCv371169,823,214 - 69,823,444UniSTSGRCm37
MGSCv371169,820,071 - 69,820,265UniSTSGRCm37
Celera1177,556,376 - 77,557,868UniSTS
Cytogenetic Map11B3UniSTS
cM Map1136.5UniSTS
cM Map1136.5UniSTS
cM Map1136.5UniSTS
DVL2__3968  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,009,233 - 70,010,062UniSTSGRCm38
MGSCv371169,822,735 - 69,823,564UniSTSGRCm37
Celera1177,557,185 - 77,558,014UniSTS
Cytogenetic Map11B3UniSTS
cM Map1136.5UniSTS
Dvl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,009,712 - 70,009,942UniSTSGRCm38
MGSCv371169,823,214 - 69,823,444UniSTSGRCm37
Celera1177,557,664 - 77,557,894UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map11B2-B5UniSTS
Dvl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,006,569 - 70,006,763UniSTSGRCm38
MGSCv371169,820,071 - 69,820,265UniSTSGRCm37
Celera1177,554,521 - 77,554,715UniSTS
Cytogenetic Map11B3UniSTS
cM Map1136.5UniSTS
Dvl2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,009,888 - 70,010,016UniSTSGRCm38
MGSCv371169,823,390 - 69,823,518UniSTSGRCm37
Celera1177,557,840 - 77,557,968UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map11B2-B5UniSTS
cM Map1136.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116910000072600000Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116910000072600000Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116910000072600000Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116910000072600000Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116910000072600000Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116910000072600000Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116910000072600000Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116910000072600000Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116910000072600000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2198
Count of miRNA genes:790
Interacting mature miRNAs:1036
Transcripts:ENSMUST00000019362, ENSMUST00000102575, ENSMUST00000130820, ENSMUST00000135422, ENSMUST00000149477, ENSMUST00000152732
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK050614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR933541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U24160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000019362   ⟹   ENSMUSP00000019362
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,000,595 - 70,010,111 (+)Ensembl
RefSeq Acc Id: ENSMUST00000102575   ⟹   ENSMUSP00000099635
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,000,617 - 70,012,301 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130820
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,000,821 - 70,006,961 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135422
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,000,835 - 70,006,013 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149477
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,005,458 - 70,007,473 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152732
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,006,980 - 70,008,069 (+)Ensembl
RefSeq Acc Id: ENSMUST00000190940   ⟹   ENSMUSP00000140073
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1170,000,617 - 70,012,301 (+)Ensembl
RefSeq Acc Id: NM_007888   ⟹   NP_031914
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,891,418 - 69,900,935 (+)NCBI
GRCm381170,000,592 - 70,010,109 (+)NCBI
MGSCv371169,814,128 - 69,823,611 (+)RGD
Celera1177,548,436 - 77,558,061 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_031914   ⟸   NM_007888
- UniProtKB: Q60838 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000140073   ⟸   ENSMUST00000190940
RefSeq Acc Id: ENSMUSP00000019362   ⟸   ENSMUST00000019362
RefSeq Acc Id: ENSMUSP00000099635   ⟸   ENSMUST00000102575
Protein Domains
DEP   DIX   PDZ

Promoters
RGD ID:6820749
Promoter ID:MM_KWN:8167
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000102575,   OTTMUST00000013482,   UC007JTL.1,   UC007JTM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,813,864 - 69,814,364 (+)MPROMDB
RGD ID:6820750
Promoter ID:MM_KWN:8168
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000013483
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,818,756 - 69,819,256 (+)MPROMDB
RGD ID:6820752
Promoter ID:MM_KWN:8169
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Liver
Transcripts:OTTMUST00000013485
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,819,991 - 69,820,892 (+)MPROMDB
RGD ID:8675280
Promoter ID:EPDNEW_M15670
Type:initiation region
Name:Dvl2_1
Description:Mus musculus dishevelled segment polarity protein 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381170,000,611 - 70,000,671EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106613 AgrOrtholog
Ensembl Genes ENSMUSG00000020888 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000019362 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000099635 UniProtKB/Swiss-Prot
  ENSMUSP00000140073 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000019362 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000102575 UniProtKB/Swiss-Prot
  ENSMUST00000190940 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.20.380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DEP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dishevelled_C-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dishevelled_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dishevelled_protein_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dsh/Dvl-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DVL2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13543 UniProtKB/Swiss-Prot
MGD MGI:106613 ENTREZGENE
NCBI Gene 13543 ENTREZGENE
PANTHER PTHR10878 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10878:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DEP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dishevelled UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dsh_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dvl2 PhenoGen
PRINTS DISHEVELLED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DISHEVELLED2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DEP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DAX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DEP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DVL2_MOUSE UniProtKB/Swiss-Prot
  I6L9H1_MOUSE UniProtKB/TrEMBL
  Q3V330_MOUSE UniProtKB/TrEMBL
  Q60838 ENTREZGENE
UniProt Secondary Q7TN14 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Dvl2  dishevelled segment polarity protein 2    dishevelled 2, dsh homolog (Drosophila)  Symbol and/or name change 5135510 APPROVED