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Gene: Pik3r5 (phosphoinositide-3-kinase regulatory subunit 5) Mus musculus
Symbol: Pik3r5
Name: phosphoinositide-3-kinase regulatory subunit 5
Description: Predicted to have 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in G protein-coupled receptor signaling pathway; positive regulation of MAP kinase activity; and regulation of phosphatidylinositol 3-kinase activity. Predicted to localize to the centriolar satellite; cytosol; and phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in ataxia with oculomotor apraxia type 3 and colon cancer. Is expressed in brain and retina nuclear layer. Orthologous to human PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-di-tert-butyl-4-methylphenol; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AV230647; F730038I15Rik; Foap2; p101; p101-PI3K; phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit; phosphoinositide 3-kinase regulatory subunit 5; phosphoinositide-3-kinase, regulatory subunit 5, p101; PI3-kinase p101 subunit; PI3-kinase regulatory subunit 5; ptdIns-3-kinase p101; ptdIns-3-kinase regulatory subunit; RP23-432M23.2
Homo sapiens (human) : PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pik3r5 (phosphoinositide-3-kinase, regulatory subunit 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pik3r5 (phosphoinositide-3-kinase regulatory subunit 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5)
Canis lupus familiaris (dog) : PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pik3r5 (phosphoinositide-3-kinase regulatory subunit 5)
Sus scrofa (pig) : PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5)
Chlorocebus sabaeus (African green monkey) : PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5)
Heterocephalus glaber (naked mole-rat) : Pik3r5 (phosphoinositide-3-kinase regulatory subunit 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1168,432,121 - 68,497,849 (+)Ensembl
GRCm381168,432,125 - 68,497,849 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371168,245,627 - 68,311,348 (+)NCBIGRCm37mm9NCBIm37
MGSCv361168,248,320 - 68,314,041 (+)NCBImm8
Celera1175,369,339 - 75,435,134 (+)NCBICelera
Cytogenetic Map11 B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Pik3r5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1620477
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.