Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | polycystic ovary syndrome | | ISO | TAB1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21411543 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | polycystic ovary syndrome | | ISO | TAB1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:21411543 | |
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# | Reference Title | Reference Citation |
1. | TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. | Brown J, etal., J Dent Res. 2011 Apr;90(4):417-27. Epub 2010 Oct 12. |
2. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
3. | Expanding role of ubiquitination in NF-kappaB signaling. | Liu S and Chen ZJ, Cell Res. 2011 Jan;21(1):6-21. Epub 2010 Dec 7. |
4. | MGDs mouse GO annotations | MGD data from the GO Consortium |
5. | MGD IEA | MGD IEA |
6. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
7. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
8. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
9. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
10. | TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme. | Verstrepen L, etal., Cell Mol Life Sci. 2008 Oct;65(19):2964-78. |
11. | Interleukin-1 (IL-1) pathway. | Weber A, etal., Sci Signal. 2010 Jan 19;3(105):cm1. doi: 10.1126/scisignal.3105cm1. |
PMID:8889548 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:12464436 | PMID:12477932 | PMID:12520002 | PMID:14610273 | PMID:15218018 | PMID:15489334 | PMID:15782199 | PMID:16141072 |
PMID:16141073 | PMID:16260493 | PMID:17205106 | PMID:17709393 | PMID:17932218 | PMID:17967808 | PMID:18021073 | PMID:18287559 | PMID:18316610 | PMID:18345001 | PMID:18693278 | PMID:18799693 |
PMID:18829460 | PMID:19026643 | PMID:19064994 | PMID:19136967 | PMID:19268530 | PMID:19556242 | PMID:20538596 | PMID:20813258 | PMID:21677750 | PMID:21789165 | PMID:21873635 | PMID:22307082 |
PMID:22331902 | PMID:22972987 | PMID:23226465 | PMID:23790753 | PMID:24037507 | PMID:24403530 | PMID:24498425 | PMID:24535827 | PMID:24736749 | PMID:24963009 | PMID:25260751 | PMID:25714464 |
PMID:25807483 | PMID:25828701 | PMID:26748475 | PMID:27695001 | PMID:28073917 | PMID:28190767 | PMID:28378742 | PMID:29143862 | PMID:30135318 | PMID:31162944 | PMID:33044562 | PMID:33378226 |
PMID:35352799 | PMID:35361962 | PMID:36409439 | PMID:36417873 | PMID:36681779 |
Tab1 (Mus musculus - house mouse) |
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TAB1 (Homo sapiens - human) |
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Tab1 (Rattus norvegicus - Norway rat) |
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Tab1 (Chinchilla lanigera - long-tailed chinchilla) |
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TAB1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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TAB1 (Canis lupus familiaris - dog) |
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Tab1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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TAB1 (Sus scrofa - pig) |
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TAB1 (Chlorocebus sabaeus - green monkey) |
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Tab1 (Heterocephalus glaber - naked mole-rat) |
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Variants in Tab1
1069 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RefSeq Transcripts | NM_025609 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006521259 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB088136 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC161199 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK003343 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK009321 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK184303 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK206012 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC027054 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC041110 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC054369 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC114637 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC134402 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BQ176587 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BY262560 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH466550 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSMUST00000023050 ⟹ ENSMUSP00000023050 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000229320 ⟹ ENSMUSP00000155204 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSMUST00000230479 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_025609 ⟹ NP_079885 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006521259 ⟹ XP_006521322 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_079885 | (Get FASTA) | NCBI Sequence Viewer |
XP_006521322 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH27054 | (Get FASTA) | NCBI Sequence Viewer |
AAH41110 | (Get FASTA) | NCBI Sequence Viewer | |
AAH54369 | (Get FASTA) | NCBI Sequence Viewer | |
AAI14638 | (Get FASTA) | NCBI Sequence Viewer | |
BAB26215 | (Get FASTA) | NCBI Sequence Viewer | |
BAC43729 | (Get FASTA) | NCBI Sequence Viewer | |
EDL04612 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSMUSP00000023050 | ||
ENSMUSP00000023050.8 | |||
ENSMUSP00000155204.2 | |||
GenBank Protein | Q8CF89 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_079885 ⟸ NM_025609 |
- UniProtKB: | Q80V65 (UniProtKB/Swiss-Prot), Q7TQJ5 (UniProtKB/Swiss-Prot), Q8R0D1 (UniProtKB/Swiss-Prot), Q8CF89 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_006521322 ⟸ XM_006521259 |
- Peptide Label: | isoform X1 |
- Sequence: |
RefSeq Acc Id: | ENSMUSP00000023050 ⟸ ENSMUST00000023050 |
RefSeq Acc Id: | ENSMUSP00000155204 ⟸ ENSMUST00000229320 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q8CF89-F1-model_v2 | AlphaFold | Q8CF89 | 1-502 | view protein structure |
RGD ID: | 6826527 | ||||||||
Promoter ID: | MM_KWN:19105 | ||||||||
Type: | CpG-Island | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | 3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen | ||||||||
Transcripts: | NM_025609 | ||||||||
Position: |
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RGD ID: | 8684394 | ||||||||
Promoter ID: | EPDNEW_M20227 | ||||||||
Type: | initiation region | ||||||||
Name: | Tab1_1 | ||||||||
Description: | Mus musculus TGF-beta activated kinase 1/MAP3K7 binding protein1 , mRNA. | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | MGI:1913763 | AgrOrtholog |
Ensembl Genes | ENSMUSG00000022414 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSMUST00000023050 | ENTREZGENE |
ENSMUST00000023050.9 | UniProtKB/Swiss-Prot | |
ENSMUST00000229320.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.60.40.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | PP2C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PPM-type_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PPM-type_phosphatase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | mmu:66513 | UniProtKB/Swiss-Prot |
MGD | MGI:1913763 | ENTREZGENE |
NCBI Gene | 66513 | ENTREZGENE |
PANTHER | PTHR13832 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | PP2C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Tab1 | PhenoGen |
PROSITE | PPM_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SMART | PP2Cc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF81606 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A2R8VK36_MOUSE | UniProtKB/TrEMBL |
Q1RMY2_MOUSE | UniProtKB/TrEMBL | |
Q7TQJ5 | ENTREZGENE | |
Q80V65 | ENTREZGENE | |
Q8CF89 | ENTREZGENE | |
Q8R0D1 | ENTREZGENE | |
Q9CV62_MOUSE | UniProtKB/TrEMBL | |
TAB1_MOUSE | UniProtKB/Swiss-Prot | |
UniProt Secondary | Q7TQJ5 | UniProtKB/Swiss-Prot |
Q80V65 | UniProtKB/Swiss-Prot | |
Q8R0D1 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2011-07-27 | Tab1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | Map3k7ip1 | mitogen-activated protein kinase kinase kinase 7 interacting protein 1 | Symbol and/or name change | 5135510 | APPROVED |