Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TAOK3 mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TAOK3 mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | increases expression | EXP | | 6480464 | vinylidene chloride results in increased expression of TAOK3 mRNA | CTD | PMID:26682919 | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of TAOK3 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TAOK3 mRNA | CTD | PMID:22206623 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of TAOK3 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TAOK3 mRNA | CTD | PMID:22298810 and PMID:34747641 | 2,4-dinitrotoluene | affects expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of TAOK3 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TAOK3 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TAOK3 mRNA | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of TAOK3 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of TAOK3 gene | CTD | PMID:31683443 | 5-fluorouracil | affects response to substance | ISO | TAOK3 (Homo sapiens) | 6480464 | TAOK3 protein affects the susceptibility to Fluorouracil | CTD | PMID:15548681 | 6-propyl-2-thiouracil | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of TAOK3 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TAOK3 mRNA | CTD | PMID:32763439 | amphetamine | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of TAOK3 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TAOK3 mRNA | CTD | PMID:33212167 | belinostat | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | belinostat results in increased expression of TAOK3 mRNA | CTD | PMID:26272509 | benzo[a]pyrene | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TAOK3 mRNA | CTD | PMID:20106945 and PMID:21632981 | benzo[a]pyrene | affects methylation | ISO | TAOK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TAOK3 5' UTR and Benzo(a)pyrene affects the methylation of TAOK3 intron | CTD | PMID:27901495 and PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TAOK3 mRNA | CTD | PMID:21932408 and PMID:33221593 | bisphenol A | increases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TAOK3 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | increases methylation | ISO | Taok3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of TAOK3 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TAOK3 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TAOK3 mRNA | CTD | PMID:26063408 | Bisphenol A diglycidyl ether | affects splicing | EXP | | 6480464 | 2 and 2-bis(4-glycidyloxyphenyl)propane affects the splicing of TAOK3 mRNA | CTD | PMID:36464114 | cadmium atom | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TAOK3 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TAOK3 mRNA | CTD | PMID:35301059 | calcitriol | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of TAOK3 mRNA | CTD | PMID:16002434 | carbamazepine | affects expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of TAOK3 mRNA | CTD | PMID:25979313 | celastrol | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | celastrol results in decreased expression of TAOK3 mRNA | CTD | PMID:17010675 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of TAOK3 mRNA | CTD | PMID:21139344 | coumarin | increases phosphorylation | ISO | TAOK3 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of TAOK3 protein | CTD | PMID:35688186 | coumestrol | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TAOK3 mRNA | CTD | PMID:19167446 | coumestrol | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of TAOK3 mRNA | CTD | PMID:19167446 | diuron | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of TAOK3 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | emodin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Emodin results in decreased expression of TAOK3 mRNA | CTD | PMID:16045814 | endosulfan | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of TAOK3 mRNA | CTD | PMID:29391264 | Enterolactone | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TAOK3 mRNA | CTD | PMID:19167446 | ethanol | decreases response to substance | EXP | | 6480464 | TAOK3 gene mutant form results in decreased susceptibility to Ethanol | CTD | PMID:23227189 | FR900359 | affects phosphorylation | ISO | TAOK3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TAOK3 protein | CTD | PMID:37730182 | furan | increases methylation | ISO | Taok3 (Rattus norvegicus) | 6480464 | furan results in increased methylation of TAOK3 gene | CTD | PMID:22079235 | furan | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | furan results in decreased expression of TAOK3 mRNA | CTD | PMID:26194646 | gedunin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | gedunin results in decreased expression of TAOK3 mRNA | CTD | PMID:17010675 | gentamycin | increases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of TAOK3 mRNA | CTD | PMID:33387578 | glycidol | increases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | glycidol results in increased expression of TAOK3 mRNA | CTD | PMID:24915197 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of TAOK3 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TAOK3 protein | CTD | PMID:32959892 | methoxychlor | affects methylation | ISO | Taok3 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of TAOK3 gene | CTD | PMID:35440735 | Nor-9-carboxy-delta9-THC | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of TAOK3 gene | CTD | PMID:30521419 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TAOK3 mRNA | CTD | PMID:17585979 | paracetamol | increases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of TAOK3 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TAOK3 mRNA | CTD | PMID:25704631 and PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TAOK3 mRNA more ... | CTD | PMID:36331819 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of TAOK3 mRNA | CTD | PMID:19270015 and PMID:23091169 | phenylmercury acetate | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of TAOK3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAOK3 mRNA | CTD | PMID:27188386 | potassium chromate | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TAOK3 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TAOK3 mRNA | CTD | PMID:22079256 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TAOK3 mRNA | CTD | PMID:28903501 | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of TAOK3 mRNA | CTD | PMID:21278054 | quercetin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of TAOK3 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TAOK3 mRNA | CTD | PMID:30851411 | raloxifene | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in increased expression of TAOK3 mRNA | CTD | PMID:19429434 | resveratrol | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TAOK3 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of TAOK3 mRNA | CTD | PMID:19013527 | SB 431542 | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TAOK3 mRNA and sodium arsenite results in decreased expression of TAOK3 protein | CTD | PMID:30528433 and PMID:34032870 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of TAOK3 mRNA | CTD | PMID:36209798 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TAOK3 mRNA | CTD | PMID:37682722 | tamoxifen | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Tamoxifen results in increased expression of TAOK3 mRNA | CTD | PMID:19429434 | Tesaglitazar | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | tesaglitazar results in decreased expression of TAOK3 mRNA | CTD | PMID:21515302 | tetrachloromethane | increases methylation | ISO | Taok3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased methylation of TAOK3 promoter | CTD | PMID:30690589 | tetrachloromethane | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of TAOK3 mRNA | CTD | PMID:30690589 and PMID:31150632 | thioacetamide | decreases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of TAOK3 mRNA | CTD | PMID:23411599 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of TAOK3 mRNA | CTD | PMID:23409001 | titanium dioxide | decreases methylation | ISO | TAOK3 (Homo sapiens) | 6480464 | titanium dioxide results in decreased methylation of TAOK3 gene | CTD | PMID:34973136 | trichloroethene | increases methylation | ISO | Taok3 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of TAOK3 gene | CTD | PMID:27618143 | trichloroethene | increases expression | ISO | Taok3 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of TAOK3 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TAOK3 mRNA | CTD | PMID:24935251 | trichostatin A | affects expression | ISO | TAOK3 (Homo sapiens) | 6480464 | trichostatin A affects the expression of TAOK3 mRNA | CTD | PMID:28542535 | triptonide | affects expression | EXP | | 6480464 | triptonide affects the expression of TAOK3 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of TAOK3 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of TAOK3 mRNA | CTD | PMID:30912803 | urethane | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Urethane results in increased expression of TAOK3 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TAOK3 mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | ISO | TAOK3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TAOK3 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TAOK3 mRNA | CTD | PMID:22083351 more ... | valproic acid | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAOK3 mRNA | CTD | PMID:27188386 | vinclozolin | increases methylation | ISO | Taok3 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of TAOK3 gene | CTD | PMID:31079544 | vorinostat | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | vorinostat results in increased expression of TAOK3 mRNA | CTD | PMID:22083351 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 2. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:11544199 | PMID:12466851 | PMID:12477932 | PMID:12520002 | PMID:14610273 | PMID:15782199 | PMID:16141072 |
| PMID:16141073 | PMID:18287559 | PMID:18799693 | PMID:21267068 | PMID:21873635 | PMID:23227189 | PMID:27256596 | PMID:28068307 | PMID:30196744 | PMID:30333137 | PMID:30550785 | PMID:32325033 |
| PMID:32560809 | PMID:32807497 | PMID:33214146 | PMID:34321999 | PMID:34506849 | PMID:37347461 | PMID:37400834 | PMID:37864157 | PMID:38166031 |
Genomics
Comparative Map Data
| Taok3 (Mus musculus - house mouse) |
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| TAOK3 (Homo sapiens - human) |
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| Taok3 (Rattus norvegicus - Norway rat) |
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| Taok3 (Chinchilla lanigera - long-tailed chinchilla) |
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| TAOK3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| TAOK3 (Canis lupus familiaris - dog) |
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| Taok3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| TAOK3 (Sus scrofa - pig) |
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| TAOK3 (Chlorocebus sabaeus - green monkey) |
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| Taok3 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Taok3
5018 total Variants 
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