Robo1 (roundabout guidance receptor 1) - Rat Genome Database

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Gene: Robo1 (roundabout guidance receptor 1) Mus musculus
Analyze
Symbol: Robo1
Name: roundabout guidance receptor 1
RGD ID: 62234
MGI Page MGI
Description: Predicted to enable LRR domain binding activity; axon guidance receptor activity; and identical protein binding activity. Involved in several processes, including circulatory system development; neuron development; and regulation of gene expression. Acts upstream of or within animal organ development; axon guidance; and negative regulation of cell population proliferation. Located in axolemma. Is expressed in several structures, including central nervous system; foot; genitourinary system; jaw; and sensory organ. Used to study cystic kidney disease and lung cancer. Orthologous to human ROBO1 (roundabout guidance receptor 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW494633; AW742721; DUTT1; Gm310; roundabout homolog 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391671,824,406 - 72,844,379 (+)NCBIGRCm39mm39
GRCm39 Ensembl1672,105,194 - 72,842,983 (+)Ensembl
GRCm381672,027,518 - 73,047,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1672,308,306 - 73,046,095 (+)EnsemblGRCm38mm10GRCm38
MGSCv371672,663,394 - 73,046,345 (+)NCBIGRCm37mm9NCBIm37
MGSCv361672,546,574 - 72,928,773 (+)NCBImm8
Celera1672,912,535 - 73,307,241 (+)NCBICelera
Cytogenetic Map16C3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3-methylcholanthrene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
androgen antagonist  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
aristolochic acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
Butylparaben  (ISO)
carbon nanotube  (EXP)
chrysene  (EXP)
clobetasol  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
folic acid  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
linuron  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (ISO)
nitrofen  (ISO)
paracetamol  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tetrachloromethane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
aorta development  (IGI)
aortic valve morphogenesis  (IGI)
axon guidance  (IMP,ISO)
axon midline choice point recognition  (IGI)
cell differentiation  (IEA)
cell migration involved in sprouting angiogenesis  (ISO)
central nervous system development  (ISO)
chemorepulsion involved in postnatal olfactory bulb interneuron migration  (ISO)
chemotaxis  (IEA)
coronary vasculature development  (IMP)
endocardial cushion formation  (IGI)
heart development  (IMP)
homophilic cell adhesion via plasma membrane adhesion molecules  (ISO)
kidney development  (IMP)
mammary duct terminal end bud growth  (IMP)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (IMP)
negative regulation of chemokine-mediated signaling pathway  (ISO)
negative regulation of gene expression  (IDA)
negative regulation of mammary gland epithelial cell proliferation  (ISO)
negative regulation of negative chemotaxis  (ISO)
nervous system development  (IEA)
olfactory bulb interneuron development  (IGI)
outflow tract septum morphogenesis  (IGI)
positive regulation of axonogenesis  (ISO)
positive regulation of gene expression  (IDA)
positive regulation of MAP kinase activity  (ISO)
positive regulation of Notch signaling pathway involved in heart induction  (IDA)
positive regulation of Rho protein signal transduction  (ISO)
positive regulation of vascular endothelial growth factor signaling pathway  (ISO)
pulmonary valve morphogenesis  (IGI)
regulation of dendrite morphogenesis  (ISO)
Roundabout signaling pathway  (ISO)
spinal cord development  (ISO)
ventricular septum development  (IMP)
ventricular septum morphogenesis  (IGI)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior commissure morphology  (IAGP)
abnormal axon extension  (IAGP)
abnormal axon guidance  (IAGP)
abnormal bone structure  (IEA)
abnormal brain commissure morphology  (IAGP)
abnormal bronchiole morphology  (IAGP)
abnormal bronchus morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal diaphragm morphology  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal dorsal telencephalic commissure morphology  (IAGP)
abnormal embryonic/fetal subventricular zone morphology  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal hippocampal commissure morphology  (IAGP)
abnormal innervation  (IAGP)
abnormal kidney morphology  (IEA)
abnormal lung development  (IAGP)
abnormal lung morphology  (IAGP)
abnormal mammary gland duct morphology  (IAGP)
abnormal neurite morphology  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal olfactory tract morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal pulmonary interalveolar septum morphology  (IAGP)
abnormal sex gland morphology  (IEA)
abnormal spinal cord lateral column morphology  (IAGP)
abnormal spinal cord ventral commissure morphology  (IAGP)
abnormal stomach position or orientation  (IAGP)
absent gastric milk in neonates  (IAGP)
aphagia  (IAGP)
bronchial epithelial hyperplasia  (IAGP)
cleft palate  (IEA)
cyanosis  (IAGP)
decreased bone mineral content  (IEA)
decreased cell migration  (IAGP)
decreased corpus callosum size  (IAGP)
decreased freezing behavior  (IEA)
decreased hippocampal commissure size  (IAGP)
diaphragmatic hernia  (IAGP)
double outlet right ventricle  (IEA)
esophagus hypoplasia  (IAGP)
heart left ventricle hypertrophy  (IEA)
heart right ventricle hypertrophy  (IEA)
hydronephrosis  (IEA)
hydroureter  (IEA)
increased carcinoma incidence  (IAGP)
increased lung adenocarcinoma incidence  (IAGP)
increased lymphoma incidence  (IAGP)
increased mammary gland epithelial cell proliferation  (IAGP)
micrognathia  (IEA)
neonatal lethality  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
no spontaneous movement  (IEA)
perinatal lethality, complete penetrance  (IAGP)
polycystic kidney  (IEA)
preweaning lethality, incomplete penetrance  (IEA)
respiratory failure  (IAGP)
short trachea  (IAGP)
small esophagus  (IAGP)
thick pulmonary interalveolar septum  (IAGP)
ventricular septal defect  (IEA)
References

Additional References at PubMed
PMID:8889548   PMID:9608531   PMID:10102269   PMID:10349636   PMID:10433822   PMID:10842075   PMID:10864954   PMID:10864955   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:11306627   PMID:11472852   PMID:11520671   PMID:11672528   PMID:11734623   PMID:11748150   PMID:11804571   PMID:11830575   PMID:11944987   PMID:12051827   PMID:12123796   PMID:12360290  
PMID:12514217   PMID:12520002   PMID:12609596   PMID:12702769   PMID:12719437   PMID:12756176   PMID:12941633   PMID:12954717   PMID:14610273   PMID:14678835   PMID:14689480   PMID:15033168  
PMID:15084255   PMID:15091338   PMID:15162513   PMID:15226823   PMID:15229646   PMID:15374951   PMID:15632069   PMID:15768400   PMID:15882093   PMID:16141072   PMID:16141073   PMID:16226035  
PMID:16284245   PMID:16291793   PMID:16439476   PMID:16602821   PMID:16690755   PMID:16715082   PMID:16844427   PMID:16854408   PMID:16923961   PMID:17360927   PMID:17376983   PMID:17392456  
PMID:17470284   PMID:17581972   PMID:17582329   PMID:17715346   PMID:17826360   PMID:18054781   PMID:18272390   PMID:18287559   PMID:18345009   PMID:18417704   PMID:18466743   PMID:18480165  
PMID:18547144   PMID:18562598   PMID:18579678   PMID:18617019   PMID:18829537   PMID:18842816   PMID:18986510   PMID:19030180   PMID:19366869   PMID:19463158   PMID:19592574   PMID:19684588  
PMID:19700621   PMID:19706539   PMID:19741192   PMID:19782674   PMID:19799774   PMID:19906969   PMID:19906978   PMID:19958120   PMID:20436479   PMID:20498081   PMID:20631173   PMID:20696379  
PMID:20941780   PMID:20947829   PMID:21118670   PMID:21215373   PMID:21267068   PMID:21307234   PMID:21421844   PMID:21435555   PMID:21508241   PMID:21600986   PMID:21655271   PMID:21664580  
PMID:21677750   PMID:21688288   PMID:21820427   PMID:22306607   PMID:22349628   PMID:22399681   PMID:22433866   PMID:22457488   PMID:22661412   PMID:22772332   PMID:22806432   PMID:22912413  
PMID:23083737   PMID:23136391   PMID:23144817   PMID:23161783   PMID:23217742   PMID:23255421   PMID:23302812   PMID:23303943   PMID:23328398   PMID:23396189   PMID:23431145   PMID:23438940  
PMID:23473743   PMID:23534961   PMID:23746841   PMID:23811810   PMID:23814012   PMID:23821580   PMID:23884932   PMID:23903657   PMID:24154525   PMID:24357327   PMID:24360543   PMID:24553291  
PMID:24560577   PMID:24673457   PMID:24741061   PMID:24952961   PMID:25030704   PMID:25056828   PMID:25336744   PMID:25366972   PMID:25456121   PMID:25485759   PMID:25530182   PMID:25605242  
PMID:25631876   PMID:25691540   PMID:25807483   PMID:25843547   PMID:25894826   PMID:25988316   PMID:26282852   PMID:26290247   PMID:26503042   PMID:26520399   PMID:26620267   PMID:26659946  
PMID:26743624   PMID:26960375   PMID:26975850   PMID:27002738   PMID:27466379   PMID:27648578   PMID:27770832   PMID:27819291   PMID:28219675   PMID:28234971   PMID:28445456   PMID:28592524  
PMID:28639940   PMID:28722174   PMID:28970231   PMID:28986144   PMID:28987541   PMID:29099309   PMID:29343636   PMID:29504949   PMID:29785024   PMID:29961574   PMID:30022126   PMID:30177526  
PMID:30392794   PMID:30504829   PMID:30504844   PMID:30661738   PMID:30661739   PMID:30674481   PMID:30685539   PMID:30726731   PMID:30758284   PMID:30893602   PMID:31008488   PMID:31070778  
PMID:31138815   PMID:31356769   PMID:31392959   PMID:31597096   PMID:32325033   PMID:32470195   PMID:32499648   PMID:32561725   PMID:32807784   PMID:33347679   PMID:34249921  


Genomics

Comparative Map Data
Robo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391671,824,406 - 72,844,379 (+)NCBIGRCm39mm39
GRCm39 Ensembl1672,105,194 - 72,842,983 (+)Ensembl
GRCm381672,027,518 - 73,047,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1672,308,306 - 73,046,095 (+)EnsemblGRCm38mm10GRCm38
MGSCv371672,663,394 - 73,046,345 (+)NCBIGRCm37mm9NCBIm37
MGSCv361672,546,574 - 72,928,773 (+)NCBImm8
Celera1672,912,535 - 73,307,241 (+)NCBICelera
Cytogenetic Map16C3.1NCBI
ROBO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl378,597,239 - 79,767,998 (-)EnsemblGRCh38hg38GRCh38
GRCh38378,597,239 - 79,767,998 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37378,646,389 - 79,817,148 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36378,729,080 - 79,721,751 (-)NCBINCBI36hg18NCBI36
Build 34378,729,079 - 79,721,751NCBI
Celera379,390,331 - 80,561,510 (-)NCBI
Cytogenetic Map3p12.3NCBI
HuRef378,666,127 - 79,837,569 (-)NCBIHuRef
CHM1_1378,599,244 - 79,770,223 (-)NCBICHM1_1
Robo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21110,580,863 - 11,621,672 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1110,580,908 - 11,620,203 (+)Ensembl
Rnor_6.0119,079,291 - 10,146,302 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl119,642,365 - 10,143,317 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01113,314,508 - 13,808,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41110,784,947 - 11,720,646 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11110,784,946 - 11,720,646 (+)NCBI
Celera1110,598,877 - 11,659,942 (+)NCBICelera
Cytogenetic Map11p11NCBI
Robo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540713,107,235 - 13,487,053 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540712,593,911 - 13,485,723 (+)NCBIChiLan1.0ChiLan1.0
ROBO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1380,579,716 - 81,001,219 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl380,581,388 - 81,569,308 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0378,707,802 - 79,876,519 (-)NCBIMhudiblu_PPA_v0panPan3
ROBO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1318,082,363 - 8,594,623 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl317,626,126 - 8,593,728 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha317,536,253 - 8,593,279 (+)NCBI
ROS_Cfam_1.0317,481,760 - 8,614,235 (+)NCBI
UMICH_Zoey_3.1317,442,809 - 8,564,392 (+)NCBI
UNSW_CanFamBas_1.0317,499,515 - 8,626,174 (+)NCBI
UU_Cfam_GSD_1.0317,883,361 - 9,008,850 (+)NCBI
Robo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049718,782,876 - 9,791,545 (+)NCBI
SpeTri2.0NW_0049365054,329,428 - 4,711,310 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ROBO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13175,505,366 - 176,479,482 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113175,348,223 - 176,479,482 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213186,417,282 - 186,884,529 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ROBO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12297,178,093 - 98,363,647 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2298,222,891 - 98,363,219 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604168,583,685 - 69,736,220 (-)NCBIVero_WHO_p1.0
Robo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248744,234,640 - 5,359,333 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AW742721  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381672,743,148 - 72,743,371UniSTSGRCm38
MGSCv371672,743,393 - 72,743,616UniSTSGRCm37
Celera1672,992,309 - 72,992,531UniSTS
Cytogenetic Map16C3.1UniSTS
Whitehead/MRC_RH16803.39UniSTS
RH136204  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381672,800,737 - 72,800,926UniSTSGRCm38
MGSCv371672,800,982 - 72,801,171UniSTSGRCm37
Celera1673,056,108 - 73,056,297UniSTS
Cytogenetic Map16C3.1UniSTS
AW494633  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381672,742,171 - 72,742,277UniSTSGRCm38
MGSCv371672,742,416 - 72,742,522UniSTSGRCm37
Celera1672,991,334 - 72,991,440UniSTS
Cytogenetic Map16C3.1UniSTS
Whitehead/MRC_RH16803.39UniSTS
D16Mit151  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381672,922,765 - 72,922,896UniSTSGRCm38
MGSCv371672,923,010 - 72,923,141UniSTSGRCm37
Celera1673,183,672 - 73,183,805UniSTS
Cytogenetic Map16C3.1UniSTS
cM Map1645.5UniSTS
Whitehead Genetic1635.0UniSTS
Whitehead/MRC_RH16803.39UniSTS
D16Mit187  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381673,000,593 - 73,000,702UniSTSGRCm38
MGSCv371673,000,838 - 73,000,947UniSTSGRCm37
Celera1673,261,705 - 73,261,818UniSTS
Cytogenetic Map16C3.1UniSTS
cM Map1645.5UniSTS
Whitehead Genetic1635.0UniSTS
Whitehead_YAC16 UniSTS
D16Mit65  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381672,864,958 - 72,865,073UniSTSGRCm38
MGSCv371672,865,203 - 72,865,318UniSTSGRCm37
Celera1673,120,310 - 73,120,415UniSTS
Cytogenetic Map16C3.1UniSTS
cM Map1645.5UniSTS
Whitehead Genetic1633.9UniSTS
Whitehead_YAC16 UniSTS
Robo1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381673,043,114 - 73,044,484UniSTSGRCm38
MGSCv371673,043,359 - 73,044,729UniSTSGRCm37
Celera1673,304,255 - 73,305,625UniSTS
Cytogenetic Map16C3.1UniSTS
cM Map16 UniSTS
Y17793  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381673,044,655 - 73,044,787UniSTSGRCm38
MGSCv371673,044,900 - 73,045,032UniSTSGRCm37
Celera1673,305,796 - 73,305,928UniSTS
Cytogenetic Map16C3.1UniSTS
Whitehead/MRC_RH16804.25UniSTS
Robo1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C3.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16860000091100000Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162020057985803938Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163562627392776120Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163750000084900000Mouse
4142112Skts-fp3_mskin tumor susceptibility in FVB and PWK 3 (mouse)Not determined164023351973127497Mouse
11522747Eae41_mexperimental allergic encephalomyelitis susceptibility 41 (mouse)164057877278218584Mouse
1301138Pcd4ts3_mp-glycoprotein positive CD4 T cell subset 3 (mouse)Not determined164077356074773713Mouse
1357778Diobq_mdiet-induced obesity QTL (mouse)Not determined164237745482534286Mouse
1301719Remslp3_mrapid eye movement sleep 3 (mouse)Not determined164456298778563143Mouse
4141212Imraq3_mimmune response to AAV2 QTL 3 (mouse)Not determined164456298778563143Mouse
10053677Eae46_mexperimental allergic encephalomyelitis susceptibility 46 (mouse)Not determined164539769878952955Mouse
1558836Dice1b_mdetermination of interleukin 4 commitment 1b (mouse)Not determined164569063772477597Mouse
14928310Manh80_mmandible shape 80 (mouse)164842295582422955Mouse
1301394Eae11_msusceptibility to experimental allergic encephalomyelitis 11 (mouse)Not determined165376500387765147Mouse
1301364Lith14_mlithogenic gene 14 (mouse)Not determined165586495889865073Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166181175695811876Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6318975897189758Mouse
1300928Etia_methanol induced activation (mouse)Not determined166351701997517128Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166353044897530584Mouse
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166880383498207768Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166927924498207768Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166933072398207768Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166933072398207768Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166933072398207768Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166945759498207768Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167058336498207768Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir218-2mmu-miR-218-5pOncomiRDBexternal_infoNANA21385904
Mir218-2mmu-miR-218-5pOncomiRDBexternal_infoNANA20300657

Predicted Target Of
Summary Value
Count of predictions:360
Count of miRNA genes:299
Interacting mature miRNAs:318
Transcripts:ENSMUST00000023600
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC136716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC164551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02118112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK781477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y17793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000023600   ⟹   ENSMUSP00000023600
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,460,037 - 72,842,983 (+)Ensembl
GRCm38.p6 Ensembl1672,663,149 - 73,046,095 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231265
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,460,092 - 72,755,132 (+)Ensembl
GRCm38.p6 Ensembl1672,663,204 - 72,958,244 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231474
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,460,072 - 72,540,279 (+)Ensembl
GRCm38.p6 Ensembl1672,663,184 - 72,743,391 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231566
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,780,643 - 72,786,766 (+)Ensembl
GRCm38.p6 Ensembl1672,983,755 - 72,989,878 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231580   ⟹   ENSMUSP00000156106
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,105,194 - 72,539,305 (+)Ensembl
GRCm38.p6 Ensembl1672,308,306 - 72,742,417 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232205   ⟹   ENSMUSP00000155958
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,360,588 - 72,842,983 (+)Ensembl
GRCm38.p6 Ensembl1672,563,700 - 73,046,095 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232264
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,775,618 - 72,800,598 (+)Ensembl
GRCm38.p6 Ensembl1672,978,730 - 73,003,710 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232432
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,803,309 - 72,805,634 (+)Ensembl
GRCm38.p6 Ensembl1673,006,421 - 73,008,746 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232545
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1672,773,237 - 72,776,106 (+)Ensembl
GRCm38.p6 Ensembl1672,976,349 - 72,979,218 (+)Ensembl
RefSeq Acc Id: NM_019413   ⟹   NP_062286
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,460,037 - 72,842,988 (+)NCBI
GRCm381672,663,149 - 73,046,100 (+)NCBI
MGSCv371672,663,394 - 73,046,345 (+)RGD
Celera1672,912,535 - 73,307,241 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522957   ⟹   XP_006523020
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,360,309 - 72,844,379 (+)NCBI
GRCm381672,563,416 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522958   ⟹   XP_006523021
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,360,307 - 72,844,379 (+)NCBI
GRCm381672,563,415 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522960   ⟹   XP_006523023
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391671,824,406 - 72,844,379 (+)NCBI
GRCm381672,027,518 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522961   ⟹   XP_006523024
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,104,882 - 72,844,379 (+)NCBI
GRCm381672,307,981 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522962   ⟹   XP_006523025
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,360,309 - 72,844,379 (+)NCBI
GRCm381672,563,416 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522963   ⟹   XP_006523026
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391671,824,443 - 72,844,379 (+)NCBI
GRCm381672,027,518 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522964   ⟹   XP_006523027
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,360,308 - 72,844,379 (+)NCBI
GRCm381672,563,415 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522965   ⟹   XP_006523028
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,452,699 - 72,844,379 (+)NCBI
GRCm381672,662,775 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316893   ⟹   XP_017172382
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,360,309 - 72,844,379 (+)NCBI
GRCm381672,563,416 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316894   ⟹   XP_017172383
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,104,880 - 72,844,379 (+)NCBI
GRCm381672,307,979 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249003   ⟹   XP_030104863
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,360,310 - 72,844,379 (+)NCBI
GRCm381672,563,417 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249005   ⟹   XP_030104865
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391672,452,699 - 72,844,379 (+)NCBI
GRCm381672,662,775 - 73,047,491 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159818   ⟹   XP_036015711
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391671,824,406 - 72,844,379 (+)NCBI
RefSeq Acc Id: XM_036159819   ⟹   XP_036015712
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391671,824,442 - 72,844,379 (+)NCBI
RefSeq Acc Id: XM_036159820   ⟹   XP_036015713
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391671,824,443 - 72,844,379 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062286   ⟸   NM_019413
- Peptide Label: precursor
- UniProtKB: O89026 (UniProtKB/Swiss-Prot),   G5E843 (UniProtKB/TrEMBL),   Q3UQ03 (UniProtKB/TrEMBL),   Q3UXH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523023   ⟸   XM_006522960
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006523026   ⟸   XM_006522963
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_006523024   ⟸   XM_006522961
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006523021   ⟸   XM_006522958
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006523027   ⟸   XM_006522964
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006523025   ⟸   XM_006522962
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006523020   ⟸   XM_006522957
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006523028   ⟸   XM_006522965
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_017172383   ⟸   XM_017316894
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017172382   ⟸   XM_017316893
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030104863   ⟸   XM_030249003
- Peptide Label: isoform X11
RefSeq Acc Id: XP_030104865   ⟸   XM_030249005
- Peptide Label: isoform X15
RefSeq Acc Id: ENSMUSP00000156106   ⟸   ENSMUST00000231580
RefSeq Acc Id: ENSMUSP00000155958   ⟸   ENSMUST00000232205
RefSeq Acc Id: ENSMUSP00000023600   ⟸   ENSMUST00000023600
RefSeq Acc Id: XP_036015711   ⟸   XM_036159818
- Peptide Label: isoform X6
RefSeq Acc Id: XP_036015712   ⟸   XM_036159819
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036015713   ⟸   XM_036159820
- Peptide Label: isoform X13
Promoters
RGD ID:13674236
Promoter ID:EPDNEW_M21267
Type:initiation region
Name:Robo1_1
Description:Mus musculus roundabout guidance receptor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381672,663,153 - 72,663,213EPDNEW
RGD ID:6827419
Promoter ID:MM_KWN:21414
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_019413,   UC007ZQZ.1,   UC007ZRA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361672,663,281 - 72,663,927 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1274781 AgrOrtholog
Ensembl Genes ENSMUSG00000022883 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023600 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000155958 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000156106 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023600 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000231580 UniProtKB/TrEMBL
  ENSMUST00000232205 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Robo1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19876 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1274781 ENTREZGENE
NCBI Gene 19876 ENTREZGENE
PANTHER PTHR12231:SF243 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Robo1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A338P6F7_MOUSE UniProtKB/TrEMBL
  A0A338P6U2_MOUSE UniProtKB/TrEMBL
  G5E843 ENTREZGENE, UniProtKB/TrEMBL
  O89026 ENTREZGENE
  Q3UQ03 ENTREZGENE, UniProtKB/TrEMBL
  Q3UQW4_MOUSE UniProtKB/TrEMBL
  Q3UUE8_MOUSE UniProtKB/TrEMBL
  Q3UXH3 ENTREZGENE, UniProtKB/TrEMBL
  ROBO1_MOUSE UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Robo1  roundabout guidance receptor 1    roundabout homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED