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Gene: Tnfrsf11a (tumor necrosis factor receptor superfamily, member 11a, NFKB activator) Mus musculus
Symbol: Tnfrsf11a
Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Description: Exhibits tumor necrosis factor-activated receptor activity. Involved in several processes, including circadian temperature homeostasis; hematopoietic or lymphoid organ development; and positive regulation of bone resorption. Localizes to the cell surface. Human ortholog(s) of this gene implicated in Paget's disease of bone; autosomal recessive osteopetrosis 7; bone development disease; and osteoporosis. Is expressed in bladder and lymphatic system. Orthologous to human TNFRSF11A (TNF receptor superfamily member 11a); PARTICIPATES IN rheumatoid arthritis pathway; INTERACTS WITH 4,4'-diaminodiphenylmethane; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ly109; mRANK; ODFR; OFE; osteoclast differentiation factor receptor; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; TRANCE-R; tumor necrosis factor receptor superfamily member 11A
Homo sapiens (human) : TNFRSF11A (TNF receptor superfamily member 11a)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfrsf11a (TNF receptor superfamily member 11A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf11a (TNF receptor superfamily member 11a)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF11A (TNF receptor superfamily member 11a)
Canis lupus familiaris (dog) : TNFRSF11A (TNF receptor superfamily member 11a)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf11a (TNF receptor superfamily member 11a)
Sus scrofa (pig) : TNFRSF11A (TNF receptor superfamily member 11a)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1105,780,718 - 105,847,981 (+)Ensembl
GRCm381105,780,673 - 105,849,444 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371107,677,300 - 107,744,558 (+)NCBIGRCm37mm9NCBIm37
MGSCv361107,608,270 - 107,672,989 (+)NCBImm8
Celera1108,658,349 - 108,696,865 (+)NCBICelera
Cytogenetic Map1 E2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tnfrsf11a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321640
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.