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ONTOLOGY REPORT - ANNOTATIONS

Term:xenobiotic metabolic process
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Accession:GO:0006805 term browser browse the term
Definition:The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:exact_synonym: xenobiotic metabolism
 related_synonym: drug metabolic process;   drug metabolism
 alt_id: GO:0017144
 xref: Wikipedia:Drug_metabolism;   Wikipedia:Xenobiotic_metabolism


show annotations for term's descendants           Sort by:
xenobiotic metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 involved_in ISO
IEA
ISS
IMP		 (PMID:18245269)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18245269 PMID:18245269 GO_REF:0000024 GO_REF:0000107, RGD:30309924 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Ahr aryl hydrocarbon receptor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein acts_upstream_of_or_within ISO PR:P30561 (PMID:9083006) RGD PMID:9083006 NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122 		JBrowse link
G Aox1 aldehyde oxidase 1 involved_in TAS
IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20444863), (PMID:22031625), (PMID:22522748), (PMID:23857892)
(MGI:5553225|PMID:23462233)		 Ensembl
UniProt
RGD		 PMID:20444863 PMID:22031625 PMID:22522748 PMID:23462233 PMID:23857892 More... GO_REF:0000024 GO_REF:0000107 MGI:5553225, RGD:730052 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Aox2 aldehyde oxidase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:59,828,084...59,916,146 		JBrowse link
G Aox3 aldehyde oxidase 3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,664,784...59,749,701
Ensembl chr 9:59,664,809...59,818,169 		JBrowse link
G Aox4 aldehyde oxidase 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,761,238...59,818,169
Ensembl chr 9:59,664,809...59,818,169 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IMP RGD PMID:18515330 RGD:2303526 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO
ISS		 (PMID:18449627)
GO_REF:0000024		 RGD
UniProt		 PMID:18449627 GO_REF:0000024 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in ISO (PMID:19219744) RGD PMID:19219744 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:2182351 (PMID:8643688)
(PMID:15327587), (PMID:19219744)		 RGD PMID:8643688 PMID:15327587 PMID:19219744 PMID:6772643 RGD:151347456 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:22888116)		 Ensembl
UniProt
RGD		 PMID:22888116 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in ISO (PMID:26937021) RGD PMID:26937021 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26937021)		 UniProt
RGD		 PMID:26937021 GO_REF:0000024 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2ab1 cytochrome P450, family 2, subfamily ab, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:80,582,633...80,591,217
Ensembl chr11:80,582,938...80,590,873 		JBrowse link
G Cyp2ac1 cytochrome P450, family 2, subfamily ac, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:20,035,823...20,058,570
Ensembl chr 9:20,033,780...20,058,837 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9425052 GO_REF:0000033, RGD:2301461 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480 		JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 involved_in TAS
IBA
IDA		 GO_REF:0000033 GO_Central
RGD		 PMID:11996101 PMID:9425052 GO_REF:0000033, RGD:1298848, RGD:2301461 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 involved_in NAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11159754 GO_REF:0000033, RGD:1299648 NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO
IBA		 (PMID:18356043), (PMID:19651758), (PMID:20061448)
GO_REF:0000033		 RGD
GO_Central		 PMID:18356043 PMID:19651758 PMID:20061448 GO_REF:0000033 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 involved_in TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:8611037 GO_REF:0000033, RGD:1298853 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019 		JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191 		JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738 		JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,009,411...237,054,555
Ensembl chr 1:237,009,368...237,054,564 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in NAS
IBA
ISO		 GO_REF:0000033
(PMID:19219744), (PMID:19651758)		 GO_Central
RGD		 PMID:19219744 PMID:19651758 PMID:12965116 GO_REF:0000033, RGD:728216 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c6v1l1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,244,891...237,283,416
Ensembl chr 1:237,244,885...237,283,160 		JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:19651758) RGD PMID:19651758
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in
NOT|involved_in		 ISO
IBA		 (PMID:15051713)
GO_REF:0000033
(PMID:18838503)		 RGD
GO_Central		 PMID:15051713 PMID:18838503 GO_REF:0000033 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209 		JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in IDA
IBA
ISO		 GO_REF:0000033
(PMID:18356043), (PMID:19219744)		 GO_Central
RGD		 PMID:18356043 PMID:19219744 PMID:8910433 GO_REF:0000033, RGD:728177 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2d5 cytochrome P450, family 2, subfamily d, polypeptide 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,899,905...113,904,458
Ensembl chr 7:113,899,890...113,904,495 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 involved_in NAS
IBA
IEA
ISO
IMP		 GO_REF:0000033
GO_REF:0000107
(PMID:18356043), (PMID:19219744)		 GO_Central
Ensembl
RGD		 PMID:18356043 PMID:19219744 PMID:12220509 PMID:21187827 GO_REF:0000033 GO_REF:0000107, RGD:625597, RGD:4892233 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828 		JBrowse link
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115 		JBrowse link
G Cyp2j16 cytochrome P450, family 2, subfamily j, polypeptide 16 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:111,089,438...111,138,918
Ensembl chr 5:111,088,674...111,139,013 		JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303 		JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563 		JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882 		JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 involved_in ISO
IBA		 (PMID:16551781)
GO_REF:0000033		 RGD
GO_Central		 PMID:16551781 GO_REF:0000033 NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IDA
ISO		 (PMID:19219744) RGD PMID:19219744 PMID:12971802 RGD:5129544 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IDA RGD PMID:12971802 RGD:5129544 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO (PMID:20667828) RGD PMID:20667828 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO MGI:5487815 (PMID:19262426) RGD PMID:19262426 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11744609)		 Ensembl
RGD		 PMID:11744609 GO_REF:0000107 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 IDA RGD PMID:17173378 RGD:1626480 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISO
IEA
ISS		 (PMID:20947616), (PMID:28783300)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20947616 PMID:28783300 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta3l1 glutathione S-transferase alpha 3 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,619,691...23,628,517
Ensembl chr 9:23,620,010...23,632,333 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 involved_in ISO
IBA		 (PMID:10329152)
GO_REF:0000033		 RGD
GO_Central		 PMID:10329152 GO_REF:0000033 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gsta6 glutathione S-transferase alpha 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 TAS RGD PMID:3020050 RGD:730286 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15970797)		 UniProt
Ensembl
RGD		 PMID:15970797 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in TAS
ISO		 (PMID:1540159) RGD PMID:1540159 PMID:3029128 RGD:728729 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Guk1 guanylate kinase 1 involved_in ISO (PMID:6306664) RGD PMID:6306664 NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in ISO
IEA		 (PMID:17827783)
GO_REF:0000107		 RGD
Ensembl		 PMID:17827783 GO_REF:0000107 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G LOC103691092 cytochrome P450 2B9-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,791,776...81,810,482
Ensembl chr 1:81,784,649...81,810,482 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 acts_upstream_of_or_within ISO MGI:3629327 (PMID:15840715) RGD PMID:15840715 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
ISS		 (PMID:12578355)
GO_REF:0000024		 RGD
UniProt		 PMID:12578355 GO_REF:0000024 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO UniProtKB:P51450 (MGI:5554367|PMID:17666523) RGD PMID:17666523 MGI:5554367 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rorc RAR-related orphan receptor C involved_in ISO UniProtKB:P51448 (MGI:5554367|PMID:17666523) RGD PMID:17666523 MGI:5554367 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 involved_in TAS
ISO
IDA		 (PMID:12471039), (PMID:20056724)
nitrofen		 RGD PMID:12471039 PMID:20056724 PMID:1513323 PMID:6959650 PMID:14754874 RGD:730083, RGD:2301075, RGD:2301063 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 involved_in ISO (PMID:20056724) RGD PMID:20056724 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) RGD PMID:28992322 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in IDA
ISO
ISS		 (PMID:7854148)
GO_REF:0000024		 RGD
UniProt		 PMID:7854148 PMID:16099924 GO_REF:0000024, RGD:5129555 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tpmt thiopurine S-methyltransferase involved_in ISO
IEA		 (PMID:18484748), (PMID:657528)
GO_REF:0000107		 RGD
Ensembl		 PMID:657528 PMID:18484748 GO_REF:0000107 NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 involved_in ISO (PMID:3141926) RGD PMID:3141926 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in
NOT|involved_in		 ISO (PMID:1910331)
(PMID:20610558)		 RGD PMID:1910331 PMID:20610558 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 TAS RGD PMID:3084479 RGD:1299519 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 involved_in ISO (PMID:21127708) RGD PMID:21127708 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
4-chlorobiphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
arsonoacetate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase involved_in IDA
IBA
ISO
IEA		 PMID:11790780
GO_REF:0000033
(PMID:25997655)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:25997655 PMID:11790780 GO_REF:0000033 GO_REF:0000107, RGD:625365 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 involved_in ISO (PMID:25997655) RGD PMID:25997655 NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248 		JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
carbon tetrachloride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 IEP RGD PMID:15270078 RGD:4891447 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901 		JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
IMP		 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:15812643 PMID:12914780 RGD:2306662, RGD:2306673 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
dichloromethane metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstt1 glutathione S-transferase theta 1 IDA RGD PMID:11453994 RGD:7794854 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
insecticide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA Deltamethrin (pyrethroid) RGD PMID:16169030 RGD:2306660 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Star steroidogenic acute regulatory protein IEP methoxychlor RGD PMID:18401575 RGD:4890969 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
nitroglycerin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:16520233 RGD:401900296 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
propylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO (MGI:5320264|PMID:21795692) RGD PMID:21795692 MGI:5320264 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
thiocyanate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpo lactoperoxidase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535 		JBrowse link
trichloroethylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 IDA RGD PMID:15987776 RGD:2301693 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:18088505 RGD:14700808 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 IDA RGD PMID:10725307 RGD:2312871 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Cryz crystallin zeta involved_in ISO
IEA
ISS		 (PMID:17497241)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17497241 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA		 (PMID:18356043), (PMID:18619574)
GO_REF:0000107		 RGD
Ensembl		 PMID:18356043 PMID:18619574 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO (PMID:19029318) RGD PMID:19029318 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in ISO
IDA		 (PMID:19029318) RGD PMID:19029318 PMID:16039681 RGD:401965478 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in
NOT|involved_in		 ISO (PMID:15051713)
(PMID:18838503)		 RGD PMID:15051713 PMID:18838503 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:15039299), (PMID:15327587), (PMID:18356043), (PMID:18619574) RGD PMID:15039299 PMID:15327587 PMID:18356043 PMID:18619574 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO MGI:5487815 (PMID:19262426) RGD PMID:19262426 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in IDA
ISO		 PMID:17112229
(PMID:8373352)		 RGD PMID:8373352 PMID:17112229 RGD:12793043 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in IDA
ISO		 PMID:17112229
(PMID:16549767), (PMID:2034681), (PMID:8373352)		 RGD PMID:2034681 PMID:8373352 PMID:16549767 PMID:17112229 RGD:12793043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:8373352)
(PMID:12069689)
GO_REF:0000107		 RGD
Ensembl		 PMID:8373352 PMID:12069689 GO_REF:0000107 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12928150)		 UniProt
RGD		 PMID:12928150 GO_REF:0000024 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO MGI:1857227 (PMID:11158245) RGD PMID:11158245 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
ISS		 (PMID:12578355)
GO_REF:0000024		 RGD
UniProt		 PMID:12578355 GO_REF:0000024 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) RGD PMID:26878724 NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
xenobiotic glucuronidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 involved_in IDA
ISO		 (PMID:15472229), (PMID:18719240), (PMID:19830808), (PMID:20056724) RGD PMID:15472229 PMID:18719240 PMID:19830808 PMID:20056724 PMID:8806713 RGD:10769352 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 involved_in ISO (PMID:20056724) RGD PMID:20056724 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:20056724) RGD PMID:20056724 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 involved_in ISO (PMID:11300766) RGD PMID:11300766 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11456
      cellular metabolic process 9554
        xenobiotic metabolic process 115
          2-nitropropane metabolic process + 0
          acetylene metabolic process + 0
          acrylonitrile metabolic process + 0
          adamantanone metabolic process + 0
          arsonoacetate metabolic process + 2
          caprolactam metabolic process + 0
          cyanamide metabolic process 0
          cyclohexanol metabolic process + 0
          cyclohexylsulfamate metabolic process 0
          dimethyl ether metabolic process 0
          dodecyl sulfate metabolic process 0
          halogenated hydrocarbon metabolic process + 4
          insecticide metabolic process + 4
          methanesulfonic acid metabolic process 0
          methyl ethyl ketone metabolic process + 0
          methyl tert-butyl ether metabolic process 0
          n-octane metabolic process + 0
          nitrilotriacetate metabolic process + 0
          nitroglycerin metabolic process 1
          nylon metabolic process + 0
          organosilicon metabolic process + 0
          pentaerythritol tetranitrate metabolic process 0
          propylene metabolic process + 1
          s-triazine compound metabolic process + 0
          tetrahydrofuran catabolic process 0
          thiocyanate metabolic process + 1
          xenobiotic catabolic process + 30
          xenobiotic glucuronidation 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10515
      response to chemical 5924
        response to xenobiotic stimulus 735
          cellular response to xenobiotic stimulus 223
            xenobiotic metabolic process 115
              2-nitropropane metabolic process + 0
              acetylene metabolic process + 0
              acrylonitrile metabolic process + 0
              adamantanone metabolic process + 0
              arsonoacetate metabolic process + 2
              caprolactam metabolic process + 0
              cyanamide metabolic process 0
              cyclohexanol metabolic process + 0
              cyclohexylsulfamate metabolic process 0
              dimethyl ether metabolic process 0
              dodecyl sulfate metabolic process 0
              halogenated hydrocarbon metabolic process + 4
              insecticide metabolic process + 4
              methanesulfonic acid metabolic process 0
              methyl ethyl ketone metabolic process + 0
              methyl tert-butyl ether metabolic process 0
              n-octane metabolic process + 0
              nitrilotriacetate metabolic process + 0
              nitroglycerin metabolic process 1
              nylon metabolic process + 0
              organosilicon metabolic process + 0
              pentaerythritol tetranitrate metabolic process 0
              propylene metabolic process + 1
              s-triazine compound metabolic process + 0
              tetrahydrofuran catabolic process 0
              thiocyanate metabolic process + 1
              xenobiotic catabolic process + 30
              xenobiotic glucuronidation 5
paths to the root