Cyp2c7 (cytochrome P450, family 2, subfamily c, polypeptide 7) - Rat Genome Database

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Gene: Cyp2c7 (cytochrome P450, family 2, subfamily c, polypeptide 7) Rattus norvegicus
No known orthologs.
Symbol: Cyp2c7
Name: cytochrome P450, family 2, subfamily c, polypeptide 7
RGD ID: 620379
Description: Predicted to enable arachidonic acid epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including response to ethanol; response to lipopolysaccharide; and response to retinoic acid. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Orthologous to human CYP2C8 (cytochrome P450 family 2 subfamily C member 8); PARTICIPATES IN arachidonic acid metabolic pathway; linoleic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Previously known as: Cyp2c39; CYPIIC7; cytochrome P450 2C7; cytochrome P450 2C7-like; cytochrome P450, 2c39; cytochrome P450F; LOC100361347; LOC100911552; LOC100911791; LOC103691183; MGC156667; P450F; PTF1; uncharacterized LOC103691183
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21237,332,641 - 237,388,714 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1237,332,659 - 237,388,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1245,750,823 - 245,806,851 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01252,856,984 - 252,912,966 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01245,510,012 - 245,565,966 (+)NCBIRnor_WKY
Rnor_6.01147,422,999 - 148,119,979 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1148,053,687 - 148,119,857 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01154,329,783 - 154,407,698 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11244,044,956 - 244,719,024 (+)NCBI
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)


References - curated
# Reference Title Reference Citation
1. Neonatal phenobarbital imprints overexpression of cytochromes P450 with associated increase in tumorigenesis and reduced life span. Agrawal AK and Shapiro BH, FASEB J. 2005 Mar;19(3):470-2. Epub 2005 Jan 5.
2. Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf. Borlakoglu JT, etal., Biochem Pharmacol. 1993 Apr 6;45(7):1373-86.
3. PPARalpha activators down-regulate CYP2C7, a retinoic acid and testosterone hydroxylase. Fan LQ, etal., Toxicology. 2004 Oct 15;203(1-3):41-8.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA. Gonzalez FJ, etal., J Biol Chem 1986 Aug 15;261(23):10667-72.
6. Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats. Hakkak R, etal., Biochem Pharmacol. 1996 Jan 12;51(1):61-9.
7. Sexual differentiation and regulation of cytochrome P-450 CYP2C7. Henderson CJ, etal., Biochim Biophys Acta. 1992 Jan 9;1118(2):99-106.
8. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
9. Complementary DNA cloning of cytochrome P-450s related to P-450(M-1) from the complementary DNA library of female rat livers. Predicted primary structures for P-450f, PB-1, and PB-1-related protein with a bizarre replacement block and their mode of transcriptional expression. Kimura H, etal., J Biol Chem 1988 Jan 15;263(2):701-7.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axis. Morgan ET Biochem Pharmacol. 1993 Jan 26;45(2):415-9.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Growth hormone-regulated periportal expression of CYP2C7 in rat liver. Oinonen T, etal., Biochem Pharmacol. 2000 Mar 1;59(5):583-9.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. GOA pipeline RGD automated data pipeline
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Comprehensive gene review and curation RGD comprehensive gene curation
19. CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids. Westin S, etal., Mol Cell Endocrinol. 1997 May 16;129(2):169-79.
Additional References at PubMed
PMID:2385231   PMID:3308889   PMID:3801454   PMID:12477932   PMID:15047867   PMID:21940400  



Variants in Cyp2c7
391 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:94
Interacting mature miRNAs:96
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210702053240947965Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
2292216Bw80Body weight QTL 803.230.0019body mass (VT:0001259)body weight (CMO:0000012)1213533809243914901Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1218753689245907899Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1224054293243747962Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1224054293243747962Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228985440245907899Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
631836Stl31Serum triglyceride level QTL 314.640.00000487blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,388,773 - 237,389,007 (-)MAPPERmRatBN7.2
Rnor_6.01147,422,697 - 147,422,934NCBIRnor6.0
Rnor_5.01153,717,763 - 153,718,000UniSTSRnor5.0
RGSC_v3.41244,028,192 - 244,028,426UniSTSRGSC3.4
RGSC_v3.41244,028,191 - 244,028,426RGDRGSC3.4
RGSC_v3.41243,702,202 - 243,702,423UniSTSRGSC3.4
RGSC_v3.11244,124,750 - 244,124,985RGD
RH 3.4 Map11617.12UniSTS
RH 3.4 Map11617.12RGD
RH 2.0 Map11222.3RGD
Cytogenetic Map1q53UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21237,388,393 - 237,388,600 (-)MAPPERmRatBN7.2
mRatBN7.21238,503,991 - 238,504,198 (+)MAPPERmRatBN7.2
Rnor_6.01147,423,108 - 147,423,314NCBIRnor6.0
Rnor_6.01148,287,138 - 148,287,344NCBIRnor6.0
Rnor_5.01154,573,938 - 154,574,144UniSTSRnor5.0
Rnor_5.01153,718,174 - 153,718,380UniSTSRnor5.0
Cytogenetic Map1q53UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21238,462,568 - 238,462,821 (+)MAPPERmRatBN7.2
Rnor_6.01148,245,719 - 148,245,971NCBIRnor6.0
Rnor_5.01154,533,195 - 154,533,442UniSTSRnor5.0
RGSC_v3.41243,972,787 - 243,973,057UniSTSRGSC3.4
RGSC_v3.41244,580,731 - 244,580,983UniSTSRGSC3.4
Celera1137,219,180 - 137,219,432UniSTS
Cytogenetic Map1q53UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 12 12 12
Medium 1 1 1 1
Low 3 19 6 12 6 6 6 9 6 10 6 6
Below cutoff 5 6 4 5 4 2 2 3 6 3 1 2


Reference Sequences
RefSeq Acc Id: ENSRNOT00000040325   ⟹   ENSRNOP00000045029
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1237,332,659 - 237,388,709 (+)Ensembl
Rnor_6.0 Ensembl1148,053,687 - 148,119,857 (-)Ensembl
RefSeq Acc Id: NM_017158   ⟹   NP_058854
Rat AssemblyChrPosition (strand)Source
mRatBN7.21237,332,762 - 237,388,709 (+)NCBI
Rnor_6.01147,422,999 - 148,119,857 (-)NCBI
Rnor_5.01154,329,783 - 154,407,698 (-)NCBI
RefSeq Acc Id: XM_039105249   ⟹   XP_038961177
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21237,339,694 - 237,388,706 (+)NCBI
RefSeq Acc Id: XR_005501918
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21237,332,641 - 237,388,714 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_058854   ⟸   NM_017158
- Peptide Label: precursor
- UniProtKB: Q63706 (UniProtKB/Swiss-Prot),   P05179 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000045029   ⟸   ENSRNOT00000040325
RefSeq Acc Id: XP_038961177   ⟸   XM_039105249
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05179-F1-model_v2 AlphaFold P05179 1-490 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690174
Promoter ID:EPDNEW_R698
Type:multiple initiation site
Description:cytochrome P450, family 2, subfamily c, polypeptide 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Rat AssemblyChrPosition (strand)Source
Rnor_6.01148,119,857 - 148,119,917EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620379 AgrOrtholog
BioCyc Gene G2FUF-55758 BioCyc
Ensembl Genes ENSRNOG00000021405 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000045029 ENTREZGENE
  ENSRNOP00000045029.5 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040325 ENTREZGENE
  ENSRNOT00000040325.6 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29298 UniProtKB/Swiss-Prot
  CYTOCHROME P450 508A4-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cyp2c7 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CP2C7_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q63706 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  LOC103691183  uncharacterized LOC103691183  Data Merged 737654 PROVISIONAL
2015-07-29 LOC103691183  uncharacterized LOC103691183  LOC100911791  cytochrome P450 2C7-like  Data Merged 737654 PROVISIONAL
2015-07-29 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  LOC100911552  cytochrome P450 2C7-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103691183  uncharacterized LOC103691183      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-04-12 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  LOC100361347  cytochrome P450 2C7-like  Data Merged 737654 PROVISIONAL
2012-07-05 LOC100911552  cytochrome P450 2C7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911791  cytochrome P450 2C7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-05 LOC100361347  cytochrome P450 2C7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Cyp2c7  cytochrome P450, family 2, subfamily c, polypeptide 7  Cyp2c39  cytochrome P450, 2c39  Symbol and Name updated 1299863 APPROVED
2002-08-07 Cyp2c39  cytochrome P450, 2c39      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expression upregulated up through 4 weeks of age 632587