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ONTOLOGY REPORT - ANNOTATIONS

Term:xenobiotic catabolic process
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Accession:GO:0042178 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:exact_synonym: xenobiotic breakdown;   xenobiotic catabolism;   xenobiotic degradation
 related_synonym: drug breakdown;   drug catabolic process;   drug catabolism;   drug degradation;   exogenous drug breakdown;   exogenous drug catabolic process;   exogenous drug catabolism;   exogenous drug degradation
 alt_id: GO:0042737;   GO:0042738


show annotations for term's descendants           Sort by:
xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:18088505 RGD:14700808 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 IDA RGD PMID:10725307 RGD:2312871 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Cryz crystallin zeta involved_in ISO
IEA
ISS		 (PMID:17497241)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17497241 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA		 (PMID:18356043), (PMID:18619574)
GO_REF:0000107		 RGD
Ensembl		 PMID:18356043 PMID:18619574 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO (PMID:19029318) RGD PMID:19029318 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in ISO
IDA		 (PMID:19029318) RGD PMID:19029318 PMID:16039681 RGD:401965478 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in
NOT|involved_in		 ISO (PMID:15051713)
(PMID:18838503)		 RGD PMID:15051713 PMID:18838503 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:15039299), (PMID:15327587), (PMID:18356043), (PMID:18619574) RGD PMID:15039299 PMID:15327587 PMID:18356043 PMID:18619574 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO MGI:5487815 (PMID:19262426) RGD PMID:19262426 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in IDA
ISO		 PMID:17112229
(PMID:8373352)		 RGD PMID:8373352 PMID:17112229 RGD:12793043 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in IDA
ISO		 PMID:17112229
(PMID:16549767), (PMID:2034681), (PMID:8373352)		 RGD PMID:2034681 PMID:8373352 PMID:16549767 PMID:17112229 RGD:12793043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:8373352)
(PMID:12069689)
GO_REF:0000107		 RGD
Ensembl		 PMID:8373352 PMID:12069689 GO_REF:0000107 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12928150)		 UniProt
RGD		 PMID:12928150 GO_REF:0000024 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO MGI:1857227 (PMID:11158245) RGD PMID:11158245 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
ISS		 (PMID:12578355)
GO_REF:0000024		 RGD
UniProt		 PMID:12578355 GO_REF:0000024 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) RGD PMID:26878724 NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
IMP		 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:15812643 PMID:12914780 RGD:2306662, RGD:2306673 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      cellular metabolic process 10294
        cellular catabolic process 1117
          xenobiotic catabolic process 30
            2-aminobenzenesulfonate catabolic process 0
            2-nitropropane catabolic process 0
            3-hydroxyphenylacetate catabolic process 0
            3-methylquinoline catabolic process 0
            3-phenylpropionate catabolic process 0
            4-nitrophenol catabolic process 0
            6-hydroxycineole catabolic process 0
            acrylonitrile catabolic process 0
            adamantanone catabolic process 0
            anaerobic acetylene catabolic process 0
            anaerobic cyclohexane-1-carboxylate catabolic process 0
            anthranilate catabolic process 0
            arsonoacetate catabolic process 0
            biphenyl catabolic process 2
            bisphenol A catabolic process 0
            caprolactam catabolic process 0
            carbazole catabolic process 0
            cresol catabolic process + 0
            dibenzo-p-dioxin catabolic process 1
            dibenzofuran catabolic process 0
            dibenzothiophene catabolic process 0
            exogenous antibiotic catabolic process 0
            fluorene catabolic process 0
            halogenated hydrocarbon catabolic process + 0
            insecticide catabolic process + 0
            methyl ethyl ketone catabolic process 0
            methylnaphthalene catabolic process 0
            nylon catabolic process 0
            organosilicon catabolic process + 0
            phenanthrene catabolic process + 0
            phenylacetate catabolic process 3
            phenylmercury acetate catabolic process 0
            phthalate catabolic process 0
            propylene catabolic process 0
            s-triazine compound catabolic process + 0
            styrene catabolic process 0
            thiocyanate catabolic process 0
            toluene catabolic process + 0
            xylene catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    cellular process 18524
      cellular response to stimulus 8719
        cellular response to chemical stimulus 2700
          cellular response to xenobiotic stimulus 227
            xenobiotic metabolic process 117
              xenobiotic catabolic process 30
                2-aminobenzenesulfonate catabolic process 0
                2-nitropropane catabolic process 0
                3-hydroxyphenylacetate catabolic process 0
                3-methylquinoline catabolic process 0
                3-phenylpropionate catabolic process 0
                4-nitrophenol catabolic process 0
                6-hydroxycineole catabolic process 0
                acrylonitrile catabolic process 0
                adamantanone catabolic process 0
                anaerobic acetylene catabolic process 0
                anaerobic cyclohexane-1-carboxylate catabolic process 0
                anthranilate catabolic process 0
                arsonoacetate catabolic process 0
                biphenyl catabolic process 2
                bisphenol A catabolic process 0
                caprolactam catabolic process 0
                carbazole catabolic process 0
                cresol catabolic process + 0
                dibenzo-p-dioxin catabolic process 1
                dibenzofuran catabolic process 0
                dibenzothiophene catabolic process 0
                exogenous antibiotic catabolic process 0
                fluorene catabolic process 0
                halogenated hydrocarbon catabolic process + 0
                insecticide catabolic process + 0
                methyl ethyl ketone catabolic process 0
                methylnaphthalene catabolic process 0
                nylon catabolic process 0
                organosilicon catabolic process + 0
                phenanthrene catabolic process + 0
                phenylacetate catabolic process 3
                phenylmercury acetate catabolic process 0
                phthalate catabolic process 0
                propylene catabolic process 0
                s-triazine compound catabolic process + 0
                styrene catabolic process 0
                thiocyanate catabolic process 0
                toluene catabolic process + 0
                xylene catabolic process + 0
paths to the root