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ONTOLOGY REPORT - ANNOTATIONS


Term:xenobiotic catabolic process
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Accession:GO:0042178 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:exact_synonym: xenobiotic breakdown;   xenobiotic catabolism;   xenobiotic degradation
 related_synonym: drug breakdown;   drug catabolic process;   drug catabolism;   drug degradation;   exogenous drug breakdown;   exogenous drug catabolic process;   exogenous drug catabolism;   exogenous drug degradation
 alt_id: GO:0042737;   GO:0042738



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xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:18088505 RGD:14700808 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 IDA RGD PMID:10725307 RGD:2312871 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Cryz crystallin zeta involved_in ISO
ISS
(PMID:17497241)
GO_REF:0000024
RGD
UniProt
PMID:17497241 GO_REF:0000024 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO (PMID:18356043), (PMID:18619574) RGD PMID:18356043 PMID:18619574 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO (PMID:19029318) RGD PMID:19029318 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 involved_in ISO (PMID:19029318) RGD PMID:19029318 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:15039299), (PMID:18356043), (PMID:18619574) RGD PMID:15039299 PMID:18356043 PMID:18619574 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO MGI:5487815 (MGI:5487534|PMID:19262426) RGD PMID:19262426 MGI:5487534 NCBI chr13:75,154,683...75,172,932
Ensembl chr13:75,154,684...75,172,874
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in IDA
ISO
PMID:17112229
(PMID:8373352)
RGD PMID:8373352 PMID:17112229 RGD:12793043 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in IDA
ISO
PMID:17112229
(PMID:16549767), (PMID:2034681), (PMID:8373352)
RGD PMID:2034681 PMID:8373352 PMID:16549767 PMID:17112229 RGD:12793043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in
acts_upstream_of_or_within
ISO (PMID:8373352)
(MGI:2387281|PMID:12069689)
RGD PMID:8373352 PMID:12069689 MGI:2387281 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:12928150)
UniProt
Ensembl
RGD
PMID:12928150 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO MGI:1857227 (MGI:1931387|PMID:11158245) RGD PMID:11158245 MGI:1931387 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
ISS
(PMID:12578355)
GO_REF:0000024
RGD
UniProt
PMID:12578355 GO_REF:0000024 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) RGD PMID:26878724 NCBI chr15:48,707,776...48,747,363
Ensembl chr15:48,709,700...48,747,363
JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
IMP
2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:15812643 PMID:12914780 RGD:2306662, RGD:2306673 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      cellular metabolic process 9699
        cellular catabolic process 2036
          xenobiotic catabolic process 28
            1,3-dichloro-2-propanol catabolic process 0
            2-aminobenzenesulfonate catabolic process 0
            2-nitropropane catabolic process 0
            3-hydroxyphenylacetate catabolic process 0
            3-methylquinoline catabolic process 0
            3-phenylpropionate catabolic process 0
            4-nitrophenol catabolic process 0
            6-hydroxycineole catabolic process 0
            acrylonitrile catabolic process 0
            adamantanone catabolic process 0
            anaerobic acetylene catabolic process 0
            anaerobic cyclohexane-1-carboxylate catabolic process 0
            anthranilate catabolic process 0
            arsonoacetate catabolic process 0
            biphenyl catabolic process 2
            bisphenol A catabolic process 0
            caprolactam catabolic process 0
            carbazole catabolic process 0
            cresol catabolic process + 0
            dibenzo-p-dioxin catabolic process 1
            dibenzofuran catabolic process 0
            dibenzothiophene catabolic process 0
            exogenous antibiotic catabolic process 0
            fluorene catabolic process 0
            halogenated hydrocarbon catabolic process + 0
            insecticide catabolic process + 0
            methyl ethyl ketone catabolic process 0
            methylnaphthalene catabolic process 0
            nylon catabolic process 0
            organosilicon catabolic process + 0
            phenanthrene catabolic process + 0
            phenylacetate catabolic process 3
            phenylmercury acetate catabolic process 0
            phthalate catabolic process 0
            propylene catabolic process 0
            s-triazine compound catabolic process + 0
            styrene catabolic process 0
            thiocyanate catabolic process 0
            toluene catabolic process + 0
            triethanolamine catabolic process 0
            xylene catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular response to stimulus 8642
        cellular response to chemical stimulus 3572
          cellular response to xenobiotic stimulus 220
            xenobiotic metabolic process 118
              xenobiotic catabolic process 28
                1,3-dichloro-2-propanol catabolic process 0
                2-aminobenzenesulfonate catabolic process 0
                2-nitropropane catabolic process 0
                3-hydroxyphenylacetate catabolic process 0
                3-methylquinoline catabolic process 0
                3-phenylpropionate catabolic process 0
                4-nitrophenol catabolic process 0
                6-hydroxycineole catabolic process 0
                acrylonitrile catabolic process 0
                adamantanone catabolic process 0
                anaerobic acetylene catabolic process 0
                anaerobic cyclohexane-1-carboxylate catabolic process 0
                anthranilate catabolic process 0
                arsonoacetate catabolic process 0
                biphenyl catabolic process 2
                bisphenol A catabolic process 0
                caprolactam catabolic process 0
                carbazole catabolic process 0
                cresol catabolic process + 0
                dibenzo-p-dioxin catabolic process 1
                dibenzofuran catabolic process 0
                dibenzothiophene catabolic process 0
                exogenous antibiotic catabolic process 0
                fluorene catabolic process 0
                halogenated hydrocarbon catabolic process + 0
                insecticide catabolic process + 0
                methyl ethyl ketone catabolic process 0
                methylnaphthalene catabolic process 0
                nylon catabolic process 0
                organosilicon catabolic process + 0
                phenanthrene catabolic process + 0
                phenylacetate catabolic process 3
                phenylmercury acetate catabolic process 0
                phthalate catabolic process 0
                propylene catabolic process 0
                s-triazine compound catabolic process + 0
                styrene catabolic process 0
                thiocyanate catabolic process 0
                toluene catabolic process + 0
                triethanolamine catabolic process 0
                xylene catabolic process + 0
paths to the root