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ONTOLOGY REPORT - ANNOTATIONS

Term:pancreas development
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Accession:GO:0031016 term browser browse the term
Definition:The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.
Synonyms:xref: Wikipedia:Pancreas


show annotations for term's descendants           Sort by:
pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108051 (PMID:17849440)		 Ensembl
RGD		 PMID:17849440 GO_REF:0000107 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Afp alpha-fetoprotein IEP RGD PMID:17880577 RGD:2292043 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 acts_upstream_of_or_within ISO MGI:1857891|MGI:2180721 (PMID:15739227), (PMID:16026781) RGD PMID:15739227 PMID:16026781 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Apc APC regulator of WNT signaling pathway IEP RGD PMID:16688812 RGD:4110129 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Cckar cholecystokinin A receptor IEP RGD PMID:10403848 RGD:2313336 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148569 (PMID:16192304)		 Ensembl
RGD		 PMID:16192304 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2183829 (PMID:11997520) RGD PMID:11997520 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:15329346) RGD PMID:15329346 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Foxf1 forkhead box F1 involved_in ISO (PMID:19500772) RGD PMID:19500772 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738 		JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:16887115) RGD PMID:16887115 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within ISO MGI:2449672 (PMID:15548585) RGD PMID:15548585 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:2149672 (PMID:19619492) RGD PMID:19619492 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO MGI:2177762 (PMID:16364283) RGD PMID:16364283 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:2157527 (PMID:11773599) RGD PMID:11773599 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1934258|MGI:98297 (PMID:10821773), (PMID:11044404) RGD PMID:10821773 PMID:11044404 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Ildr2 immunoglobulin-like domain containing receptor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3820395 (PMID:18654634)		 GO_Central
RGD		 PMID:18654634 GO_REF:0000033 NCBI chr13:78,518,770...78,580,627
Ensembl chr13:78,518,802...78,576,924 		JBrowse link
G Invs inversin acts_upstream_of_or_within ISO MGI:1856915 (PMID:9771707) RGD PMID:9771707 NCBI chr 5:62,610,916...62,763,813
Ensembl chr 5:62,610,968...62,763,350 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2182246 (PMID:9000074)		 Ensembl
RGD		 PMID:9000074 GO_REF:0000107 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Meis2 Meis homeobox 2 IEP RGD PMID:15660282 RGD:2304272 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:8954115 GO_REF:0000033, RGD:2317563 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within ISO MGI:2182358 (PMID:10471501) RGD PMID:10471501 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465 		JBrowse link
G Msln mesothelin IEP RGD PMID:18505465 RGD:2326046 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Nkx3-2 NK3 homeobox 2 acts_upstream_of_or_within ISO MGI:1931319 (PMID:15329346) RGD PMID:15329346 NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061 		JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:1891408|MGI:2179340 (PMID:17400205) RGD PMID:17400205 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (PMID:17400205) RGD PMID:17400205 NCBI chr18:57,831,647...57,890,884
Ensembl chr18:57,832,111...57,879,629 		JBrowse link
G Pax2 paired box 2 involved_in ISO (PMID:1723950) RGD PMID:1723950 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP RGD PMID:17221210 RGD:2308896 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within IEP
ISO		 MGI:2152755|MGI:2181362 (PMID:16418487), (PMID:8625829) RGD PMID:8625829 PMID:16418487 PMID:18778483 RGD:2311165 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Pnliprp1 pancreatic lipase-related protein 1 IEP RGD PMID:8203536 RGD:728275 NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:11789987) RGD PMID:11789987 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Ptf1a pancreas associated transcription factor 1a involved_in
acts_upstream_of_or_within		 ISO (PMID:15543146)
MGI:2387804|MGI:3771319 (PMID:17938243)		 RGD PMID:15543146 PMID:17938243 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135 		JBrowse link
G Rbm4 RNA binding motif protein 4 acts_upstream_of_or_within ISO MGI:5467987|MGI:5467988 (PMID:23129807) RGD PMID:23129807 NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
G Selenot selenoprotein T involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
MGI:5544732 (PMID:23913443)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23913443 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934261|MGI:96533 (PMID:10821773), (PMID:11044404)		 Ensembl
RGD		 PMID:10821773 PMID:11044404 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smad2 SMAD family member 2 acts_upstream_of_or_within ISO MGI:87912 (PMID:17849440) RGD PMID:17849440 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:16479313 RGD:2302093 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein IEP RGD PMID:19916172 RGD:8694406 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
branching involved in pancreas morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO MGI:3609548 (PMID:22178591) RGD PMID:22178591 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
determination of pancreatic left/right asymmetry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit involved_in ISO (PMID:22693285) RGD PMID:22693285 NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350 		JBrowse link
G Ccdc40 coiled-coil domain 40 molecular ruler complex subunit involved_in ISO (PMID:22693285) RGD PMID:22693285 NCBI chr10:104,486,748...104,527,284
Ensembl chr10:104,486,748...104,527,243 		JBrowse link
G Dnaaf1 dynein, axonemal, assembly factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19944405)		 Ensembl
RGD		 PMID:19944405 GO_REF:0000107 NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313 		JBrowse link
G Nphp3 nephrocystin 3 involved_in ISO (PMID:20007846) RGD PMID:20007846 NCBI chr 8:104,621,908...104,662,383
Ensembl chr 8:104,621,864...104,662,383 		JBrowse link
G Zic3 Zic family member 3 involved_in ISO (PMID:9354794) RGD PMID:9354794 NCBI chr  X:136,123,662...136,129,627
Ensembl chr  X:136,124,026...136,134,746 		JBrowse link
endocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IEP RGD PMID:7527053 RGD:2306957 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 IEP RGD PMID:11000281 RGD:2315710 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Clu clusterin IMP RGD PMID:16411126 RGD:1582421 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12086964)		 UniProt
RGD		 PMID:12086964 GO_REF:0000024 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Foxa2 forkhead box A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2177337|MGI:2664968 (PMID:15680365)
(PMID:12124776)		 Ensembl
RGD		 PMID:12124776 PMID:15680365 GO_REF:0000107 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gip gastric inhibitory polypeptide acts_upstream_of_or_within ISO (PMID:21270265) RGD PMID:21270265 NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor acts_upstream_of_or_within ISO (PMID:21270265) RGD PMID:21270265 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in ISO
ISS		 (PMID:16801329)
PMID:1677179		 RGD PMID:16801329 PMID:1677179 RGD:8554679 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:18719127) RGD PMID:18719127 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO
IEA		 (PMID:18719127)
GO_REF:0000107		 RGD
Ensembl		 PMID:18719127 GO_REF:0000107 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (PMID:16511571) RGD PMID:16511571 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2182358 (PMID:10471501)		 GO_Central
RGD		 PMID:10471501 GO_REF:0000033 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465 		JBrowse link
G Myt1 myelin transcription factor 1 acts_upstream_of_or_within ISO (PMID:17928203) RGD PMID:17928203 NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341 		JBrowse link
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10639171), (PMID:9308961)		 UniProt
RGD		 PMID:9308961 PMID:10639171 GO_REF:0000024 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (PMID:9584121) RGD PMID:9584121 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO MGI:1352738|MGI:2386119 (PMID:15944193) RGD PMID:15944193 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within ISO MGI:1206039 (PMID:15944193) RGD PMID:15944193 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515 		JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:1891408 (PMID:17400205) RGD PMID:17400205 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (PMID:17400205) RGD PMID:17400205 NCBI chr18:57,831,647...57,890,884
Ensembl chr18:57,832,111...57,879,629 		JBrowse link
G Pde3b phosphodiesterase 3B acts_upstream_of_or_within ISO (PMID:14736883) RGD PMID:14736883 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (PMID:18155690) RGD PMID:18155690 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (PMID:17229940) RGD PMID:17229940 NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032) RGD PMID:20148032 NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Sox4 SRY-box transcription factor 4 acts_upstream_of_or_within ISO MGI:2182092 (PMID:16306355) RGD PMID:16306355 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2385469 (PMID:18723011) RGD PMID:18723011 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Zfp800 zinc finger protein 800 acts_upstream_of_or_within ISO MGI:6716236 (PMID:33653874) RGD PMID:33653874 NCBI chr 4:56,798,326...56,849,766
Ensembl chr 4:56,826,997...56,849,791 		JBrowse link
exocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 acts_upstream_of_or_within ISO MGI:2148594 (PMID:17222338) RGD PMID:17222338 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1926485 (PMID:12101187) RGD PMID:12101187 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor acts_upstream_of_or_within ISO MGI:1926486 (PMID:12101187) RGD PMID:12101187 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 acts_upstream_of_or_within ISO MGI:2677156 (PMID:12101187) RGD PMID:12101187 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Insr insulin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857204 (PMID:12101187)		 Ensembl
RGD		 PMID:12101187 GO_REF:0000107 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2388676 (PMID:16126192) RGD PMID:16126192 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Ptf1a pancreas associated transcription factor 1a involved_in IDA PMID:10768861 UniProt PMID:10768861 RGD:8554373 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135 		JBrowse link
G Srp54a signal recognition particle 54A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:72,587,584...72,626,878
Ensembl chr 6:72,587,605...72,625,189 		JBrowse link
G Wls Wnt ligand secretion mediator involved_in ISO (PMID:20614471) RGD PMID:20614471 NCBI chr 2:248,931,885...249,047,248
Ensembl chr 2:248,931,903...249,048,298 		JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2386788 (PMID:16362047)
GO_REF:0000107		 RGD
Ensembl		 PMID:16362047 GO_REF:0000107 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2149672 (PMID:10615124)		 Ensembl
RGD		 PMID:10615124 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Mir7-1 microRNA 7-1 acts_upstream_of_or_within ISO (PMID:22764048) RGD PMID:22764048 NCBI chr17:6,273,264...6,273,360
Ensembl chr17:6,273,264...6,273,360 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:23178930 RGD:11567224 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
pancreas morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 acts_upstream_of_or_within ISO MGI:2148594 (PMID:17222338) RGD PMID:17222338 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 acts_upstream_of_or_within ISO (PMID:25063451) RGD PMID:25063451 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176256|MGI:2684317 (PMID:20185815)		 Ensembl
RGD		 PMID:20185815 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in IMP
ISO
IEA		 PMID:20592023
(PMID:20592023)
GO_REF:0000107		 RGD
Ensembl		 PMID:20592023 PMID:20592023 GO_REF:0000107, RGD:8552352 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16887115)		 Ensembl
RGD		 PMID:16887115 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2149672 (PMID:10615124)		 Ensembl
RGD		 PMID:10615124 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:16511571) RGD PMID:16511571 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO MGI:1352738 (PMID:15944193) RGD PMID:15944193 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within ISO MGI:1206039 (PMID:15944193) RGD PMID:15944193 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515 		JBrowse link
G Onecut1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179340 (PMID:10825208)		 Ensembl
RGD		 PMID:10825208 GO_REF:0000107 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Pax6 paired box 6 IMP RGD PMID:20592023 RGD:8552352 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032) RGD PMID:20148032 NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (PMID:25186293) RGD PMID:25186293 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 acts_upstream_of_or_within ISO MGI:97347 (PMID:17988662) RGD PMID:17988662 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1339708|MGI:1932100 (PMID:17202186), (PMID:17988662) RGD PMID:17202186 PMID:17988662 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Onecut1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179340 (PMID:10825208)		 Ensembl
RGD		 PMID:10825208 GO_REF:0000107 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032) RGD PMID:20148032 NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032) RGD PMID:20148032 NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 acts_upstream_of_or_within ISO MGI:97347 (PMID:17988662) RGD PMID:17988662 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1339708 (PMID:17988662) RGD PMID:17988662 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18223655)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18223655 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (PMID:20413507) RGD PMID:20413507 NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20562852)		 UniProt
RGD		 PMID:20562852 GO_REF:0000024 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Clock clock circadian regulator involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20562852)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20562852 GO_REF:0000024 GO_REF:0000107 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO
IEA		 (PMID:19258434)
GO_REF:0000107		 RGD
Ensembl		 PMID:19258434 GO_REF:0000107 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA
ISS		 (PMID:11865031)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11865031 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:11865031) RGD PMID:11865031 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:11865031) RGD PMID:11865031 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Cdh2 cadherin 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:26750727)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26750727 GO_REF:0000024 GO_REF:0000107 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:20668294) RGD PMID:20668294 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:22529374)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22529374 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO MGI:3656035 (PMID:16951258) RGD PMID:16951258 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Mir214 microRNA 214 acts_upstream_of_or_within ISO (PMID:17804764) RGD PMID:17804764 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir375 microRNA 375 acts_upstream_of_or_within ISO (PMID:17804764) RGD PMID:17804764 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir503 microRNA 503 acts_upstream_of_or_within ISO (PMID:17804764) RGD PMID:17804764 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir541 microRNA 541 acts_upstream_of_or_within ISO (PMID:17804764) RGD PMID:17804764 NCBI chr 6:128,757,016...128,757,105
Ensembl chr 6:128,757,016...128,757,105 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (PMID:17202186), (PMID:17456846) RGD PMID:17202186 PMID:17456846 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 IEP RGD PMID:9603781 RGD:2326025 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19635472)		 Ensembl
RGD		 PMID:19635472 GO_REF:0000107 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5532825 (PMID:23776622)		 Ensembl
RGD		 PMID:23776622 GO_REF:0000107 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176256|MGI:2684317 (PMID:20185815)		 Ensembl
RGD		 PMID:20185815 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857617 (PMID:16246260)		 Ensembl
RGD		 PMID:16246260 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16887115)		 Ensembl
RGD		 PMID:16887115 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:16511571) RGD PMID:16511571 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Men1 menin 1 IMP RGD PMID:24157940 RGD:9589069 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir7-1 microRNA 7-1 acts_upstream_of_or_within ISO (PMID:22764048) RGD PMID:22764048 NCBI chr17:6,273,264...6,273,360
Ensembl chr17:6,273,264...6,273,360 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of ISO MGI:1932100 (PMID:14729487) RGD PMID:14729487 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO MGI:2386119 (PMID:15944193) RGD PMID:15944193 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Onecut1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179340 (PMID:10825208)		 Ensembl
RGD		 PMID:10825208 GO_REF:0000107 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Pax4 paired box 4 acts_upstream_of
involved_in		 ISO
IBA		 MGI:2182122 (PMID:14729487)
GO_REF:0000033		 RGD
GO_Central		 PMID:14729487 GO_REF:0000033 NCBI chr 4:57,058,453...57,065,995
Ensembl chr 4:57,058,462...57,063,408 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IMP
IBA
ISO
IEA		 GO_REF:0000033
MGI:1934347 (PMID:22764048)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:22764048 PMID:22403172 GO_REF:0000033 GO_REF:0000107, RGD:8552355 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA		 PMID:21108535
MGI:2181362 (PMID:16418487)
GO_REF:0000033
(PMID:12124776), (PMID:24567802)		 RGD
GO_Central		 PMID:12124776 PMID:16418487 PMID:24567802 PMID:21108535 GO_REF:0000033, RGD:8553608 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Reg1a regenerating family member 1 alpha involved_in ISO MGI:2446480 (PMID:16405968) RGD PMID:16405968 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032) RGD PMID:20148032 NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (PMID:25186293) RGD PMID:25186293 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (PMID:17202186), (PMID:17988662) RGD PMID:17202186 PMID:17988662 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family, member a15 acts_upstream_of_or_within ISO MGI:2182768 (PMID:16423820) RGD PMID:16423820 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within ISO MGI:2449672 (PMID:15548585) RGD PMID:15548585 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (PMID:20413507) RGD PMID:20413507 NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    developmental process 7076
      anatomical structure development 6578
        animal organ development 3678
          pancreas development 99
            determination of pancreatic left/right asymmetry 5
            endocrine pancreas development + 55
            exocrine pancreas development 10
            pancreas morphogenesis + 4
paths to the root