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ONTOLOGY REPORT - ANNOTATIONS

Term:endocrine pancreas development
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Accession:GO:0031018 term browser browse the term
Definition:The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.


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endocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:7527053 PMID:21873635 RGD:2306957, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 IEP RGD PMID:11000281 RGD:2315710 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Clu clusterin IMP RGD PMID:16411126 RGD:1582421 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12086964)		 UniProt
RGD		 PMID:12086964 GO_REF:0000024 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Foxa2 forkhead box A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2177337|MGI:2664968 (MGI:3530180|PMID:15680365)
(PMID:12124776)		 Ensembl
RGD		 PMID:12124776 PMID:15680365 GO_REF:0000107 MGI:3530180 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gip gastric inhibitory polypeptide acts_upstream_of_or_within ISO (MGI:4940930|PMID:21270265) RGD PMID:21270265 MGI:4940930 NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor acts_upstream_of_or_within ISO (MGI:4940930|PMID:21270265) RGD PMID:21270265 MGI:4940930 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462 		JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO MGI:2154359 (MGI:1266996|PMID:9593777) RGD PMID:9593777 MGI:1266996 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in ISO
ISS		 (PMID:16801329)
PMID:1677179		 RGD PMID:16801329 PMID:1677179 RGD:8554679 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:3807360|PMID:18719127) RGD PMID:18719127 MGI:3807360 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO
IEA		 (PMID:18719127)
GO_REF:0000107		 RGD
Ensembl		 PMID:18719127 GO_REF:0000107 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3619850|PMID:16511571) RGD PMID:16511571 MGI:3619850 NCBI chr 3:133,639,790...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2182358 (MGI:1344214|PMID:10471501)		 RGD PMID:10471501 PMID:21873635 MGI:1344214, RGD:13792537 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465 		JBrowse link
G Myt1 myelin transcription factor 1 acts_upstream_of_or_within ISO (MGI:3763794|PMID:17928203) RGD PMID:17928203 MGI:3763794 NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341 		JBrowse link
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:1096974|PMID:9308961), (MGI:1352314|PMID:10639171)		 UniProt
RGD		 PMID:9308961 PMID:10639171 GO_REF:0000024 MGI:1096974 MGI:1352314 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Neurog3 neurogenin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:30,079,780...30,081,262
Ensembl chr20:30,079,780...30,081,262 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:1270972|PMID:9584121) RGD PMID:9584121 MGI:1270972 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO MGI:1352738|MGI:2386119 (MGI:3579924|PMID:15944193) RGD PMID:15944193 MGI:3579924 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within ISO MGI:1206039 (MGI:3579924|PMID:15944193) RGD PMID:15944193 MGI:3579924 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515 		JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:1891408 (MGI:3710726|PMID:17400205) RGD PMID:17400205 MGI:3710726 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (MGI:3710726|PMID:17400205) RGD PMID:17400205 MGI:3710726 NCBI chr18:57,831,647...57,881,287
Ensembl chr18:57,832,111...57,879,629 		JBrowse link
G Pde3b phosphodiesterase 3B acts_upstream_of_or_within ISO (MGI:3040550|PMID:14736883) RGD PMID:14736883 MGI:3040550 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (MGI:3771560|PMID:18155690) RGD PMID:18155690 MGI:3771560 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:3713191|PMID:17229940) RGD PMID:17229940 MGI:3713191 NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (PMID:20148032) RGD PMID:20148032 NCBI chr20:31,020,221...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Sox4 SRY-box transcription factor 4 acts_upstream_of_or_within ISO MGI:2182092 (MGI:3611650|PMID:16306355) RGD PMID:16306355 MGI:3611650 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2385469 (MGI:3815251|PMID:18723011) RGD PMID:18723011 MGI:3815251 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2149672 (MGI:1351379|PMID:10615124)		 Ensembl
RGD		 PMID:10615124 GO_REF:0000107 MGI:1351379 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Mir7-1 microRNA 7-1 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) RGD PMID:22764048 MGI:5437569 NCBI chr17:6,273,264...6,273,360
Ensembl chr17:6,273,264...6,273,360 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:23178930 RGD:11567224 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 involved_in IMP
IEA
ISO		 PMID:20592023
GO_REF:0000107
(MGI:4943812|PMID:20592023)
(PMID:20592023)		 Ensembl
RGD		 PMID:20592023 PMID:20592023 GO_REF:0000107 MGI:4943812, RGD:8552352 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3701716|PMID:16887115)		 Ensembl
RGD		 PMID:16887115 GO_REF:0000107 MGI:3701716 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of
involved_in		 ISO
IEA		 MGI:2149672 (MGI:1351379|PMID:10615124)
GO_REF:0000107		 RGD
Ensembl		 PMID:10615124 GO_REF:0000107 MGI:1351379 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3619850|PMID:16511571) RGD PMID:16511571 MGI:3619850 NCBI chr 3:133,639,790...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1352738 (MGI:3579924|PMID:15944193)
GO_REF:0000107		 RGD
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1206039 (MGI:3579924|PMID:15944193)
GO_REF:0000107		 RGD
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515 		JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:2179340 (MGI:1859126|PMID:10825208) RGD PMID:10825208 MGI:1859126 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Pax6 paired box 6 IMP RGD PMID:20592023 RGD:8552352 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (MGI:4422104|PMID:20148032) RGD PMID:20148032 MGI:4422104 NCBI chr20:31,020,221...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:5618205 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 acts_upstream_of_or_within ISO MGI:97347 (MGI:3768695|PMID:17988662) RGD PMID:17988662 MGI:3768695 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1339708|MGI:1932100 (MGI:3703458|PMID:17202186), (MGI:3768695|PMID:17988662) RGD PMID:17202186 PMID:17988662 MGI:3703458 MGI:3768695 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:2179340 (MGI:1859126|PMID:10825208) RGD PMID:10825208 MGI:1859126 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (MGI:4422104|PMID:20148032) RGD PMID:20148032 MGI:4422104 NCBI chr20:31,020,221...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx6 regulatory factor X, 6 involved_in ISO (MGI:4422104|PMID:20148032) RGD PMID:20148032 MGI:4422104 NCBI chr20:31,020,221...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 acts_upstream_of_or_within ISO MGI:97347 (MGI:3768695|PMID:17988662) RGD PMID:17988662 MGI:3768695 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1339708 (MGI:3768695|PMID:17988662) RGD PMID:17988662 MGI:3768695 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISS
ISO		 GO_REF:0000024
(MGI:3778846|PMID:18223655)		 UniProt
RGD		 PMID:18223655 GO_REF:0000024 MGI:3778846 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:4941444|PMID:20413507) RGD PMID:20413507 MGI:4941444 NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like involved_in ISS
ISO		 GO_REF:0000024
(MGI:4819446|PMID:20562852)		 UniProt
RGD		 PMID:20562852 GO_REF:0000024 MGI:4819446 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Clock clock circadian regulator involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4819446|PMID:20562852)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20562852 GO_REF:0000024 GO_REF:0000107 MGI:4819446 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in ISO (PMID:19258434) RGD PMID:19258434 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA
ISS		 (PMID:11865031)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11865031 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:11865031) RGD PMID:11865031 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:11865031) RGD PMID:11865031 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Cdh2 cadherin 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6216737|PMID:26750727)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26750727 GO_REF:0000024 GO_REF:0000107 MGI:6216737 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:20668294) RGD PMID:20668294 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5426345|PMID:22529374)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22529374 GO_REF:0000024 GO_REF:0000107 MGI:5426345 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Insm1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO MGI:3656035 (MGI:3655758|PMID:16951258) RGD PMID:16951258 MGI:3655758 NCBI chr 3:133,639,790...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Mir214 microRNA 214 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir375 microRNA 375 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir503 microRNA 503 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir541 microRNA 541 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) RGD PMID:17804764 MGI:3775688 NCBI chr 6:128,757,016...128,757,105
Ensembl chr 6:128,757,016...128,757,105 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:3703458|PMID:17202186), (MGI:3761395|PMID:17456846) RGD PMID:17202186 PMID:17456846 MGI:3703458 MGI:3761395 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 IEP RGD PMID:9603781 RGD:2326025 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (MGI:4365695|PMID:19635472) RGD PMID:19635472 MGI:4365695 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 acts_upstream_of_or_within ISO MGI:5532825 (MGI:5529865|PMID:23776622) RGD PMID:23776622 MGI:5529865 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176256|MGI:2684317 (MGI:4833770|PMID:20185815)		 Ensembl
RGD		 PMID:20185815 GO_REF:0000107 MGI:4833770 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:3663526|PMID:16246260) RGD PMID:16246260 MGI:3663526 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3701716|PMID:16887115)		 Ensembl
RGD		 PMID:16887115 GO_REF:0000107 MGI:3701716 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3619850|PMID:16511571) RGD PMID:16511571 MGI:3619850 NCBI chr 3:133,639,790...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Men1 menin 1 IMP RGD PMID:24157940 RGD:9589069 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir7-1 microRNA 7-1 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) RGD PMID:22764048 MGI:5437569 NCBI chr17:6,273,264...6,273,360
Ensembl chr17:6,273,264...6,273,360 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of ISO MGI:1932100 (MGI:2686854|PMID:14729487) RGD PMID:14729487 MGI:2686854 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO MGI:2386119 (MGI:3579924|PMID:15944193) RGD PMID:15944193 MGI:3579924 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:2179340 (MGI:1859126|PMID:10825208) RGD PMID:10825208 MGI:1859126 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Pax4 paired box 4 acts_upstream_of
involved_in		 ISO
IEA		 MGI:2182122 (MGI:2686854|PMID:14729487)
GO_REF:0000107		 RGD
Ensembl		 PMID:14729487 GO_REF:0000107 MGI:2686854 NCBI chr 4:57,058,453...57,065,995
Ensembl chr 4:57,058,462...57,063,408 		JBrowse link
G Pax6 paired box 6 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:1934347 (MGI:5437569|PMID:22764048)
GO_REF:0000107		 RGD
Ensembl		 PMID:22764048 PMID:22403172 GO_REF:0000107 MGI:5437569, RGD:8552355 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA		 PMID:21108535
MGI:2181362 (MGI:3612374|PMID:16418487)
PMID:21873635
(PMID:12124776), (PMID:24567802)		 RGD PMID:12124776 PMID:16418487 PMID:24567802 PMID:21108535 PMID:21873635 MGI:3612374, RGD:8553608, RGD:13792537 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Reg1a regenerating family member 1 alpha involved_in ISO MGI:2446480 (MGI:3615755|PMID:16405968) RGD PMID:16405968 MGI:3615755 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO (MGI:4422104|PMID:20148032) RGD PMID:20148032 MGI:4422104 NCBI chr20:31,020,221...31,073,266
Ensembl chr20:31,019,829...31,073,147 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:5618205 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Zbed6 zinc finger, BED-type containing 6 involved_in ISO (MGI:5511070|PMID:24043816) RGD PMID:24043816 MGI:5511070 NCBI chr13:45,107,489...45,113,141
Ensembl chr13:45,071,718...45,114,009 		JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:3703458|PMID:17202186), (MGI:3768695|PMID:17988662) RGD PMID:17202186 PMID:17988662 MGI:3703458 MGI:3768695 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlha15 basic helix-loop-helix family, member a15 acts_upstream_of_or_within ISO MGI:2182768 (MGI:3611530|PMID:16423820) RGD PMID:16423820 MGI:3611530 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Gdf11 growth differentiation factor 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2449672 (MGI:3512831|PMID:15548585)
GO_REF:0000107		 RGD
Ensembl		 PMID:15548585 GO_REF:0000107 MGI:3512831 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725 		JBrowse link
G Rfx3 regulatory factor X3 involved_in ISO (MGI:4941444|PMID:20413507) RGD PMID:20413507 MGI:4941444 NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        endocrine pancreas development 58
          pancreatic A cell differentiation + 12
          pancreatic D cell differentiation + 2
          pancreatic PP cell differentiation + 2
          pancreatic epsilon cell differentiation + 1
          type B pancreatic cell differentiation + 37
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        multicellular organism development 5440
          system development 4941
            endocrine system development 177
              endocrine pancreas development 58
                pancreatic A cell differentiation + 12
                pancreatic D cell differentiation + 2
                pancreatic PP cell differentiation + 2
                pancreatic epsilon cell differentiation + 1
                type B pancreatic cell differentiation + 37
paths to the root