Gipr (gastric inhibitory polypeptide receptor) - Rat Genome Database

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Gene: Gipr (gastric inhibitory polypeptide receptor) Rattus norvegicus
Analyze
Symbol: Gipr
Name: gastric inhibitory polypeptide receptor
RGD ID: 2689
Description: Enables gastric inhibitory peptide receptor activity and peptide hormone binding activity. Involved in several processes, including desensitization of G protein-coupled receptor signaling pathway; positive regulation of cell communication; and response to glucose. Located in plasma membrane. Used to study type 2 diabetes mellitus. Biomarker of hyperglycemia. Human ortholog(s) of this gene implicated in cardiovascular system disease; diabetes mellitus; and obesity. Orthologous to human GIPR (gastric inhibitory polypeptide receptor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: gastric inhibitory peptide receptor; GIP-R; Gippr; glucose-dependent insulinotropic polypeptide receptor; RATGIPPR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2178,804,287 - 78,814,462 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl178,805,593 - 78,814,462 (-)Ensembl
Rnor_6.0180,063,047 - 80,073,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,063,049 - 80,073,223 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,329,939 - 81,340,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,515,051 - 78,526,160 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1178,593,161 - 78,604,271 (-)NCBI
Celera173,269,949 - 73,280,124 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Boylan MO, etal., Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1287-95. Epub 2006 Jan 10.
2. Buhren BA, etal., J Neurosci Res. 2009 Jun;87(8):1858-70.
3. Cho GJ, etal., Curr Eye Res. 2002 Dec;25(6):381-8.
4. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. GOA data from the GO Consortium
6. Harada N, etal., Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E61-8. Epub 2007 Oct 30.
7. Herbach N, etal., Am J Physiol Renal Physiol. 2009 Apr;296(4):F819-29. Epub 2009 Feb 11.
8. Herbach N, etal., Regul Pept. 2005 Feb 15;125(1-3):103-17.
9. Kato S, etal., Acta Neuropathol. 1992;83(3):277-82.
10. Lewis JT, etal., Endocrinology. 2000 Oct;141(10):3710-6.
11. Lynn FC, etal., Diabetes 2001 May;50(5):1004-11.
12. Lynn FC, etal., FASEB J 2003 Jan;17(1):91-3.
13. Miyawaki K, etal., Nat Med 2002 Jul;8(7):738-42.
14. Miyawaki K, etal., Proc Natl Acad Sci U S A 1999 Dec 21;96(26):14843-7.
15. NCBI rat LocusLink and RefSeq merged data July 26, 2002
16. Nitz I, etal., Mol Nutr Food Res. 2007 Aug;51(8):1046-52.
17. RGD automated data pipeline
18. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. RGD automated import pipeline for gene-chemical interactions
20. Rudovich N, etal., Regul Pept. 2007 Aug 16;142(3):138-45. Epub 2007 Feb 23.
21. Shu L, etal., Hum Mol Genet. 2009 Jul 1;18(13):2388-99. Epub 2009 Apr 21.
22. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
23. Tseng CC and Zhang XY, Mol Cell Endocrinol. 1998 Apr 30;139(1-2):179-86.
24. Tseng CC, etal., Am J Physiol. 1996 Apr;270(4 Pt 1):E661-6.
25. Tseng CC, etal., J Clin Invest. 1996 Dec 1;98(11):2440-5.
26. Usdin TB, etal., Endocrinology 1993 Dec;133(6):2861-70.
27. Vogel CI, etal., BMC Med Genet. 2009 Mar 2;10:19.
28. Zhou J, etal., Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E538-47. Epub 2007 May 15.
Additional References at PubMed
PMID:15716418   PMID:17360984   PMID:17803965   PMID:20332343   PMID:21270265   PMID:22778220   PMID:23689510   PMID:24360021   PMID:26395740   PMID:33321289  


Genomics

Comparative Map Data
Gipr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2178,804,287 - 78,814,462 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl178,805,593 - 78,814,462 (-)Ensembl
Rnor_6.0180,063,047 - 80,073,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,063,049 - 80,073,223 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,329,939 - 81,340,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,515,051 - 78,526,160 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1178,593,161 - 78,604,271 (-)NCBI
Celera173,269,949 - 73,280,124 (-)NCBICelera
Cytogenetic Map1q21NCBI
GIPR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,668,221 - 45,683,722 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1945,668,221 - 45,683,722 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,171,479 - 46,186,980 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,863,342 - 50,877,557 (+)NCBINCBI36hg18NCBI36
Build 341950,863,341 - 50,877,557NCBI
Celera1942,977,625 - 42,991,837 (+)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1942,600,524 - 42,614,679 (+)NCBIHuRef
CHM1_11946,174,972 - 46,189,186 (+)NCBICHM1_1
T2T-CHM13v2.01948,495,760 - 48,511,255 (+)NCBI
Gipr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,889,988 - 18,904,173 (-)NCBIGRCm39mm39
GRCm39 Ensembl718,889,986 - 18,900,052 (-)Ensembl
GRCm38719,156,063 - 19,170,248 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,156,061 - 19,166,127 (-)EnsemblGRCm38mm10GRCm38
MGSCv37719,742,474 - 19,751,476 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,315,453 - 18,324,649 (-)NCBImm8
Celera716,568,476 - 16,578,046 (-)NCBICelera
Cytogenetic Map7A3NCBI
Gipr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574140,307 - 156,899 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955574140,307 - 153,684 (+)NCBIChiLan1.0ChiLan1.0
GIPR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11951,213,090 - 51,225,293 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,213,090 - 51,225,293 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01942,673,553 - 42,688,059 (+)NCBIMhudiblu_PPA_v0panPan3
GIPR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,898,617 - 109,909,331 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,899,874 - 109,909,410 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,383,520 - 109,394,464 (-)NCBI
ROS_Cfam_1.01110,431,638 - 110,442,592 (-)NCBI
ROS_Cfam_1.0 Ensembl1110,431,641 - 110,441,388 (-)Ensembl
UMICH_Zoey_3.11110,107,193 - 110,118,149 (-)NCBI
UNSW_CanFamBas_1.01109,741,834 - 109,752,781 (-)NCBI
UU_Cfam_GSD_1.01110,610,695 - 110,621,654 (-)NCBI
Gipr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,697,897 - 17,715,171 (+)NCBI
SpeTri2.0NW_0049367062,052,069 - 2,062,722 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GIPR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,022,681 - 52,033,954 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,022,667 - 52,033,959 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GIPR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,108,319 - 39,122,973 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl639,110,387 - 39,122,874 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607318,735,245 - 18,751,098 (+)NCBIVero_WHO_p1.0
Gipr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,497,258 - 7,507,212 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248327,497,147 - 7,507,123 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D1Wox30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,804,569 - 78,804,684 (+)MAPPERmRatBN7.2
Rnor_6.0180,063,332 - 80,063,446NCBIRnor6.0
Rnor_5.0181,330,224 - 81,330,338UniSTSRnor5.0
RGSC_v3.4178,515,333 - 78,515,448RGDRGSC3.4
RGSC_v3.4178,515,334 - 78,515,448UniSTSRGSC3.4
RGSC_v3.1178,593,444 - 78,593,559RGD
Celera173,270,232 - 73,270,346UniSTS
RH 3.4 Map1789.0RGD
RH 3.4 Map1789.0UniSTS
Cytogenetic Map1q21UniSTS
RH144450  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,804,500 - 78,804,725 (+)MAPPERmRatBN7.2
Rnor_6.0180,063,263 - 80,063,487NCBIRnor6.0
Rnor_5.0181,330,155 - 81,330,379UniSTSRnor5.0
RGSC_v3.4178,515,265 - 78,515,489UniSTSRGSC3.4
Celera173,270,163 - 73,270,387UniSTS
RH 3.4 Map1812.5UniSTS
Cytogenetic Map1q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:443
Count of miRNA genes:236
Interacting mature miRNAs:291
Transcripts:ENSRNOT00000021456
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 18
Low 3 18 17 4 19 4 56 10 20 5
Below cutoff 15 22 19 19 7 9 24 21 6 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000021456   ⟹   ENSRNOP00000021456
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,805,593 - 78,814,462 (-)Ensembl
Rnor_6.0 Ensembl180,063,049 - 80,073,223 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112788   ⟹   ENSRNOP00000081882
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,805,593 - 78,814,462 (-)Ensembl
RefSeq Acc Id: NM_012714   ⟹   NP_036846
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2178,804,287 - 78,814,462 (-)NCBI
Rnor_6.0180,063,049 - 80,073,223 (-)NCBI
Rnor_5.0181,329,939 - 81,340,229 (-)NCBI
RGSC_v3.4178,515,051 - 78,526,160 (-)RGD
Celera173,269,949 - 73,280,124 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_036846 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC37637 (Get FASTA)   NCBI Sequence Viewer  
  EDM08230 (Get FASTA)   NCBI Sequence Viewer  
  EDM08231 (Get FASTA)   NCBI Sequence Viewer  
  P43219 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_036846   ⟸   NM_012714
- Peptide Label: precursor
- UniProtKB: P43219 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021456   ⟸   ENSRNOT00000021456
RefSeq Acc Id: ENSRNOP00000081882   ⟸   ENSRNOT00000112788

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P43219-F1-model_v2 AlphaFold P43219 1-455 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2689 AgrOrtholog
BioCyc Gene G2FUF-60527 BioCyc
Ensembl Genes ENSRNOG00000015860 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000021456 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021456 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.1240.10 UniProtKB/Swiss-Prot
InterPro GPCR_2-like UniProtKB/Swiss-Prot
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot
  GPCR_2_GIP_rcpt UniProtKB/Swiss-Prot
  GPCR_2_secretin-like UniProtKB/Swiss-Prot
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot
KEGG Report rno:25024 UniProtKB/Swiss-Prot
NCBI Gene 25024 ENTREZGENE
Pfam 7tm_2 UniProtKB/Swiss-Prot
  HRM UniProtKB/Swiss-Prot
PhenoGen Gipr PhenoGen
PRINTS GIPRECEPTOR UniProtKB/Swiss-Prot
  GPCRSECRETIN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot
SMART HormR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF111418 UniProtKB/Swiss-Prot
TIGR TC220766
UniProt GIPR_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Gipr  gastric inhibitory polypeptide receptor    gastric inhibitory peptide receptor  Name updated 1299863 APPROVED
2002-06-10 Gipr  gastric inhibitory peptide receptor      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease may be associated with type 2 diabetes 68929
gene_disease decreased mRNA and protein expression is detected in pancreatic islets of the Vancouver diabetic fatty Zucker rat 68929
gene_function receptor for GIP (gastric inhibitory peptide) 68929
gene_process potentiates glucose-induced insulin secretion from the pancreatic beta cells 68929