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ONTOLOGY REPORT - ANNOTATIONS

Term:vitamin metabolic process
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Accession:GO:0006766 term browser browse the term
Definition:The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
Synonyms:exact_synonym: vitamin metabolism


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biotin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btd biotinidase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:4888510 (PMID:21051254)
MGI:4888510 (PMID:24075304)		 GO_Central
RGD		 PMID:21051254 PMID:24075304 GO_REF:0000033 NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,862,407...6,940,945 		JBrowse link
G Hlcs holocarboxylase synthetase involved_in ISO MGI:6446223 (PMID:35385533) RGD PMID:35385533 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 involved_in ISO MGI:5493496 (PMID:23104561) RGD PMID:23104561 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712 		JBrowse link
calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISO
IEA
IBA		 (PMID:15465040)
GO_REF:0000117
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:15465040 GO_REF:0000033 GO_REF:0000117 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA
IBA		 (PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
GO_REF:0000117
GO_REF:0000033
(MGI:3590419|PMID:15972816)		 RGD
UniProt
GO_Central		 PMID:9415400 PMID:15795327 PMID:15972816 PMID:16549446 PMID:17023519 More... GO_REF:0000033 GO_REF:0000117 MGI:3590419 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 involved_in ISO (PMID:15465040), (PMID:18511070) RGD PMID:15465040 PMID:18511070 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
cobalamin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cubn cubilin IMP RGD PMID:14576052 RGD:8554807 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231 		JBrowse link
cobalamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd4 ATP binding cassette subfamily D member 4 involved_in ISO (PMID:22922874), (PMID:33845046) RGD PMID:22922874 PMID:33845046 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276 		JBrowse link
G Amn amnion associated transmembrane protein involved_in ISO (PMID:14576052) RGD PMID:14576052 NCBI chr 6:130,311,372...130,318,815
Ensembl chr 6:130,311,372...130,318,815 		JBrowse link
G Cubn cubilin involved_in IEA
ISO		 GO_REF:0000107
(PMID:14576052)		 Ensembl
RGD		 PMID:14576052 GO_REF:0000107 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231 		JBrowse link
G Mmaa metabolism of cobalamin associated A involved_in ISO (PMID:31056463) RGD PMID:31056463 NCBI chr19:28,619,060...28,649,319
Ensembl chr19:28,619,087...28,649,319 		JBrowse link
G Mmab metabolism of cobalamin associated B involved_in ISO (PMID:12514191) RGD PMID:12514191 NCBI chr12:42,159,109...42,172,518
Ensembl chr12:42,159,089...42,172,490 		JBrowse link
G Mmachc metabolism of cobalamin associated C involved_in ISO
IBA		 (PMID:19700356), (PMID:22642810), (PMID:23825108)
GO_REF:0000033		 RGD
GO_Central		 PMID:19700356 PMID:22642810 PMID:23825108 GO_REF:0000033 NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601 		JBrowse link
G Mmadhc metabolism of cobalamin associated D involved_in IEA
ISO
ISS		 GO_REF:0000002
GO_REF:0000107
(PMID:22156578), (PMID:24722857)
GO_REF:0000024		 InterPro
Ensembl
RGD
UniProt		 PMID:22156578 PMID:24722857 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:34,708,649...34,726,554
Ensembl chr 3:34,708,649...34,726,771 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in IEA
ISO		 GO_REF:0000107
MGI:2180496 (PMID:11158293)
(PMID:23825108)		 Ensembl
RGD		 PMID:11158293 PMID:23825108 GO_REF:0000107 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:17369066) RGD PMID:17369066 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 NOT|involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212 		JBrowse link
folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IDA PMID:1848231 UniProt PMID:1848231 RGD:632027 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO (MGI:6489626|PMID:33168096) RGD PMID:33168096 MGI:6489626 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IBA		 PMID:20424322
GO_REF:0000033		 GO_Central PMID:20424322 GO_REF:0000033, RGD:10054082 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Folr1 folate receptor alpha acts_upstream_of_or_within ISO MGI:2383986 (PMID:12854656) RGD PMID:12854656 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5512657|PMID:24074862)
(PMID:11466310)		 UniProt
RGD		 PMID:11466310 PMID:24074862 GO_REF:0000024 MGI:5512657 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:11278996) RGD PMID:11278996 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:22820017
(PMID:15769935)
MGI:4239556 (PMID:20410296)		 RGD PMID:15769935 PMID:20410296 PMID:22820017 RGD:13825440 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO MGI:5008171 (PMID:20410296) RGD PMID:20410296 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,205,677...40,227,766
Ensembl chr15:40,205,665...40,227,874 		JBrowse link
G Rgn regucalcin involved_in ISS
ISO
IBA		 GO_REF:0000024
MGI:2670511 (MGI:5486063|PMID:23349732), (PMID:16585534)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:16585534 PMID:23349732 GO_REF:0000024 GO_REF:0000033 MGI:5486063 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
L-ascorbic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within ISO MGI:88107 (PMID:33544780) RGD PMID:33544780 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:88106 (PMID:33544780) RGD PMID:33544780 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Clstn3 calsyntenin 3 involved_in ISO (PMID:34673103)
(MGI:6728656|PMID:33672967)		 RGD PMID:33672967 PMID:34673103 MGI:6728656 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within ISO (PMID:28106121) RGD PMID:28106121 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2429419 (PMID:11118286) RGD PMID:11118286 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO
IBA
ISS		 (PMID:11511179)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:11511179 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISO
IBA
IEA
ISS		 (PMID:15970797)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:15970797 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:27085842 RGD:26884454 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Selenon selenoprotein N acts_upstream_of_or_within ISO (PMID:28106121) RGD PMID:28106121 NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059 		JBrowse link
G Slc23a2 solute carrier family 23 member 2 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:10331392 GO_REF:0000033, RGD:634186 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 involved_in ISO
ISS
IEA		 (PMID:33495566)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:33495566 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) RGD PMID:19502595 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
nicotinamide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnmt nicotinamide N-methyltransferase involved_in ISO (MGI:5708799|PMID:26168293)
(PMID:21823666), (PMID:8182091)		 RGD PMID:8182091 PMID:21823666 PMID:26168293 MGI:5708799 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
pantothenate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vnn1 vanin 1 involved_in ISO
IBA		 (PMID:11491533), (PMID:25478849)
GO_REF:0000033		 RGD
GO_Central		 PMID:11491533 PMID:25478849 GO_REF:0000033 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
G Vnn3 vanin 3 involved_in ISO
IBA		 (MGI:2149227|PMID:11491533)
GO_REF:0000033		 RGD
GO_Central		 PMID:11491533 GO_REF:0000033 MGI:2149227 NCBI chr 1:21,571,364...21,583,626
Ensembl chr 1:21,571,364...21,583,626 		JBrowse link
phylloquinone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 IDA menadione catabolism RGD PMID:16359670 RGD:2316273 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbr3 carbonyl reductase 3 IDA menadione catabolism RGD PMID:18983987 RGD:2316293 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in ISO (PMID:24138531) RGD PMID:24138531 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229 		JBrowse link
positive regulation of cobalamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clybl citramalyl-CoA lyase involved_in ISO
IEA		 (MGI:5926841|PMID:29056341)
GO_REF:0000107		 RGD
Ensembl		 PMID:29056341 GO_REF:0000107 MGI:5926841 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695 		JBrowse link
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rdh10 retinol dehydrogenase 10 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572 		JBrowse link
G Rdh16 retinol dehydrogenase 16 IMP RGD PMID:21138835 RGD:6771354 NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:9282826) RGD PMID:9282826 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:1690216) RGD PMID:1690216 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
G Pdxkl1 pyridoxal kinase like 1 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr20:10,162,934...10,192,572
Ensembl chr20:10,164,099...10,192,739 		JBrowse link
pyridoxal metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase involved_in ISO (PMID:33318193) RGD PMID:33318193 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase IDA RGD PMID:2988502 RGD:2303018 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:12824491)
GO_REF:0000033
(MGI:7489789|PMID:9601034)		 RGD
GO_Central		 PMID:9601034 PMID:12824491 GO_REF:0000033 MGI:7489789 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871 		JBrowse link
pyridoxal phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxp pyridoxal phosphatase involved_in IEA
ISO
ISS		 GO_REF:0000107
MGI:6367625 (MGI:5545856|PMID:24338687), (MGI:5545857|PMID:24338473), (MGI:6695679|PMID:25783190), (PMID:30327125)
(PMID:14522954), (PMID:8132548)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:8132548 PMID:14522954 PMID:24338473 PMID:24338687 PMID:25783190 More... GO_REF:0000024 GO_REF:0000107 MGI:5545856 MGI:5545857 MGI:6695679 NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963 		JBrowse link
pyridoxal phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated involved_in ISO (MGI:76012|PMID:7550313) RGD PMID:7550313 MGI:76012 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Pdxk pyridoxal kinase involved_in ISO (PMID:31935373), (PMID:33318193) RGD PMID:31935373 PMID:33318193 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in ISO (PMID:31935373) RGD PMID:31935373 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871 		JBrowse link
pyridoxamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxk pyridoxal kinase involved_in ISO (PMID:31935373) RGD PMID:31935373 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in ISO (PMID:31935373) RGD PMID:31935373 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871 		JBrowse link
pyridoxine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871 		JBrowse link
regulation of cobalamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clybl citramalyl-CoA lyase involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:5926841|PMID:29056341)
(PMID:29056341)		 UniProt
GO_Central
RGD		 PMID:29056341 GO_REF:0000024 GO_REF:0000033 MGI:5926841 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695 		JBrowse link
regulation of vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:18000880 RGD:10400849 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3775943 (PMID:18093975) RGD PMID:18093975 NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
regulation of vitamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd320 CD320 molecule acts_upstream_of_or_within ISO MGI:3858540 (PMID:23430977) RGD PMID:23430977 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976 		JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in ISO (PMID:10823918)
(PMID:9250660)		 RGD PMID:9250660 PMID:10823918 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in IMP
ISO		 (PMID:10823918) RGD PMID:10823918 PMID:21138835 RGD:6771354 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 involved_in ISO (PMID:14532297) RGD PMID:14532297 NCBI chr 1:235,458,961...235,468,433
Ensembl chr 1:235,459,356...235,466,842 		JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 involved_in ISO (PMID:26936974) RGD PMID:26936974 NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421 		JBrowse link
riboflavin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfk riboflavin kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
Ensembl chr  X:214,799,825...214,807,438 		JBrowse link
G Rfk-ps3 riboflavin kinase, pseudogene 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:86,510,729...86,512,353 JBrowse link
riboflavin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flad1 flavin adenine dinucleotide synthetase 1 involved_in ISO (PMID:28402850) RGD PMID:28402850 NCBI chr 2:174,819,451...174,828,921
Ensembl chr 2:174,819,453...174,828,977 		JBrowse link
G Rfk riboflavin kinase involved_in ISO
IBA		 (PMID:19641494)
MGI:4356069 (PMID:24272050)
GO_REF:0000033		 RGD
GO_Central		 PMID:19641494 PMID:24272050 GO_REF:0000033 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
Ensembl chr  X:214,799,825...214,807,438 		JBrowse link
G Rfk-ps3 riboflavin kinase, pseudogene 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:86,510,729...86,512,353 JBrowse link
G Slc52a2 solute carrier family 52 member 2 involved_in ISO (PMID:23911957), (PMID:26791833) RGD PMID:23911957 PMID:26791833 NCBI chr 7:108,246,003...108,267,642
Ensembl chr 7:108,262,612...108,268,034 		JBrowse link
G Slc52a3 solute carrier family 52 member 3 involved_in IEA
ISO		 GO_REF:0000107
MGI:4363008 (PMID:33116204)		 Ensembl
RGD		 PMID:33116204 GO_REF:0000107 NCBI chr 3:140,498,924...140,515,845
Ensembl chr 3:140,509,473...140,514,096 		JBrowse link
thiamine diphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a2 solute carrier family 19 member 2 involved_in ISO (PMID:8186267) RGD PMID:8186267 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172 		JBrowse link
G Slc19a3 solute carrier family 19 member 3 involved_in ISO MGI:4948864 (PMID:28665968), (PMID:8186267) RGD PMID:8186267 PMID:28665968 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337 		JBrowse link
G Slc25a19 solute carrier family 25 member 19 involved_in ISO MGI:3691853 (PMID:17035501), (PMID:8186267) RGD PMID:8186267 PMID:17035501 NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447 		JBrowse link
G Thtpa thiamine triphosphatase involved_in IEA
ISO		 GO_REF:0000107
(PMID:18276586)		 Ensembl
RGD		 PMID:18276586 GO_REF:0000107 NCBI chr15:28,567,619...28,571,580
Ensembl chr15:28,567,323...28,571,580 		JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 involved_in IEA
ISO
IBA		 GO_REF:0000041
(PMID:11342111), (PMID:38547260)
(PMID:10567383)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:10567383 PMID:11342111 PMID:38547260 GO_REF:0000033 GO_REF:0000041 NCBI chr 4:72,170,134...72,557,707
Ensembl chr 4:72,170,134...72,557,694 		JBrowse link
thiamine diphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thtpa thiamine triphosphatase involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:3796446|PMID:18276586)		 UniProt
GO_Central
RGD		 PMID:18276586 GO_REF:0000024 GO_REF:0000033 MGI:3796446 NCBI chr15:28,567,619...28,571,580
Ensembl chr15:28,567,323...28,571,580 		JBrowse link
thiamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3849266|PMID:18940592)		 Ensembl
RGD		 PMID:18940592 GO_REF:0000107 MGI:3849266 NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236 		JBrowse link
G Thtpa thiamine triphosphatase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:28,567,619...28,571,580
Ensembl chr15:28,567,323...28,571,580 		JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 acts_upstream_of_or_within ISO (PMID:10567383) RGD PMID:10567383 NCBI chr 4:72,170,134...72,557,707
Ensembl chr 4:72,170,134...72,557,694 		JBrowse link
vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2451080 (PMID:27354281)		 Ensembl
RGD		 PMID:27354281 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lrat lecithin retinol acyltransferase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (MGI:6414681|PMID:28758396)
(PMID:11108736)
GO_REF:0000033		 RGD
GO_Central		 PMID:11108736 PMID:28758396 GO_REF:0000033 MGI:6414681 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Rbp1 retinol binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15632377)		 UniProt
RGD		 PMID:15632377 GO_REF:0000024 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
vitamin D catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in TAS
IBA
IDA
ISO		 GO_REF:0000033
PMID:16617161
(PMID:16617161), (PMID:24893882), (PMID:29461981), (PMID:8506296), (PMID:8679605)
PMID:10231362		 GO_Central
RGD		 PMID:8506296 PMID:8679605 PMID:16617161 PMID:24893882 PMID:29461981 More... GO_REF:0000033, RGD:625496, RGD:14995311, RGD:14995316 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IBA
IDA
IEA		 (MGI:1097206|PMID:9295274)
GO_REF:0000033
PMID:9333115
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:9295274 PMID:9333115 GO_REF:0000033 GO_REF:0000107 MGI:1097206, RGD:69373 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:29461981) RGD PMID:29461981 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:15040831) RGD PMID:15040831 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
vitamin D metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb1 calbindin 1 TAS RGD PMID:2792772 RGD:68751 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 acts_upstream_of_or_within IDA
ISO
TAS		 MGI:2182338 (PMID:15225763) RGD PMID:15225763 PMID:1991512 PMID:12372434 RGD:1298844, RGD:734870 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in TAS
ISO
IDA		 (PMID:9415400) RGD PMID:9415400 PMID:11316734 PMID:9371776 RGD:68680, RGD:69372 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 acts_upstream_of_or_within ISO (PMID:12867411) RGD PMID:12867411 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Fgf23 fibroblast growth factor 23 IEP RGD PMID:15531762 RGD:1598934 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Gc GC, vitamin D binding protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15225763)		 Ensembl
RGD		 PMID:15225763 GO_REF:0000107 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10052453)		 Ensembl
RGD		 PMID:10052453 GO_REF:0000107 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
vitamin D3 metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:28798354) RGD PMID:28798354 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:95525 (PMID:24259513) RGD PMID:24259513 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 acts_upstream_of_or_within ISO MGI:95522 (PMID:24259513) RGD PMID:24259513 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 involved_in ISO (PMID:23756265) RGD PMID:23756265 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 involved_in ISO (PMID:18177842), (PMID:24641623) RGD PMID:18177842 PMID:24641623 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pltp phospholipid transfer protein acts_upstream_of_or_within ISO MGI:2176342 (PMID:16467369) RGD PMID:16467369 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
vitamin E metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:16520233 RGD:401900296 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:28315682) RGD PMID:28315682 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9271353)		 UniProt
RGD		 PMID:9271353 GO_REF:0000024 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Ttpa alpha tocopherol transfer protein involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (MGI:4461120|PMID:19923370)
MGI:1932559|MGI:2386172 (PMID:11076932), (PMID:11095717), (PMID:16014812)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:11076932 PMID:11095717 PMID:16014812 PMID:19923370 GO_REF:0000033 GO_REF:0000107 MGI:4461120 NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073 		JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:20953171), (PMID:23169578)		 UniProt
GO_Central
RGD		 PMID:20953171 PMID:23169578 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
vitamin K catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in ISO (PMID:24138531) RGD PMID:24138531 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229 		JBrowse link
vitamin K metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm2 apoptosis inducing factor, mitochondria associated 2 involved_in ISO (PMID:35922516) RGD PMID:35922516 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO
ISS		 (PMID:18449627)
GO_REF:0000024		 RGD
UniProt		 PMID:18449627 GO_REF:0000024 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Crcp CGRP receptor component involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225 		JBrowse link
G ENSRNOG00000070855 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:34,016,445...34,017,156 JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in IEA
ISO		 GO_REF:0000107
(PMID:17073445)		 Ensembl
RGD		 PMID:17073445 GO_REF:0000107 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in IDA
ISO		 PMID:8999809
(MGI:85821|PMID:8999809)
(PMID:8999809)		 RGD PMID:8999809 PMID:8999809 MGI:85821, RGD:151356617 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:15879509)
GO_REF:0000033
(PMID:16270630), (PMID:33154105)
GO_REF:0000002
(MGI:5559848|PMID:19492146)		 UniProt
RGD
GO_Central
InterPro		 PMID:15879509 PMID:16270630 PMID:19492146 PMID:33154105 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 MGI:5559848 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 involved_in ISO
IBA
IEA
IDA		 (PMID:21367861)
GO_REF:0000033
GO_REF:0000002
(MGI:5559651|PMID:23928358)		 RGD
GO_Central
InterPro		 PMID:21367861 PMID:23928358 PMID:23928358 GO_REF:0000002 GO_REF:0000033 MGI:5559651, RGD:8553362 NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19870
    metabolic process 11602
      small molecule metabolic process 1876
        vitamin metabolic process 101
          fat-soluble vitamin metabolic process + 43
          negative regulation of vitamin metabolic process + 4
          positive regulation of vitamin metabolic process + 5
          regulation of vitamin metabolic process + 12
          vitamin biosynthetic process + 25
          vitamin catabolic process + 15
          water-soluble vitamin metabolic process + 53
paths to the root