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ONTOLOGY REPORT - ANNOTATIONS
Term:vitamin metabolic process
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Accession:GO:0006766 term browser browse the term
Definition:The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
Synonyms:exact_synonym: vitamin metabolism

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vitamin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cubn cubilin JBrowse link 17 80,584,921 80,807,181 RGD:628443
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:628443
RGD:1600115
RGD:1624291
anthranilate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:1600115
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1624291
RGD:13792537
biotin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btd biotinidase JBrowse link 16 7,758,192 7,791,301 RGD:1624291
RGD:13792537
calcitriol biosynthetic process from calciol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 JBrowse link 1 184,060,521 184,106,604 RGD:1624291
cobalamin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cubn cubilin JBrowse link 17 80,584,921 80,807,181 RGD:8554807
cobalamin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcd4 ATP binding cassette subfamily D member 4 JBrowse link 6 108,315,026 108,329,550 RGD:1624291
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase JBrowse link 9 78,862,013 78,882,061 RGD:5135263
G Cblif cobalamin binding intrinsic factor JBrowse link 1 228,118,048 228,132,296 RGD:1624368
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase JBrowse link 11 31,780,477 31,805,728 RGD:5135263
G Mmachc metabolism of cobalamin associated C JBrowse link 5 135,555,587 135,561,723 RGD:1624291
G Mmadhc metabolism of cobalamin associated D JBrowse link 3 35,783,511 35,801,474 RGD:1600115
RGD:1624291
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 17 66,210,444 66,295,014 RGD:1624291
RGD:1600115
folic acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mthfs methenyltetrahydrofolate synthetase JBrowse link 8 96,564,877 96,614,386 RGD:1624291
G Pm20d2 peptidase M20 domain containing 2 JBrowse link 5 48,416,005 48,437,054 RGD:13792537
folic acid metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:10054082
RGD:13792537
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Gnmt glycine N-methyltransferase JBrowse link 9 16,565,274 16,568,626 RGD:728472
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 1 37,743,089 37,774,485 RGD:1624291
RGD:1600115
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:13792537
L-ascorbic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:13825440
RGD:13792537
RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:70644
G Gulo gulonolactone (L-) oxidase JBrowse link 15 42,671,206 42,693,711 RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:1624291
RGD:13792537
RGD:1600115
L-ascorbic acid metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1600115
RGD:1624291
G Gsto2 glutathione S-transferase omega 2 JBrowse link 1 267,617,517 267,640,455 RGD:1624291
RGD:1600115
G LOC103690044 glutathione S-transferase omega-2 JBrowse link 1 271,228,018 271,243,517 RGD:1600115
G Slc23a2 solute carrier family 23 member 2 JBrowse link 3 124,632,491 124,842,225 RGD:634186
RGD:13792537
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
pantothenate metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vnn1 vanin 1 JBrowse link 1 22,614,832 22,625,134 RGD:1624291
RGD:13792537
G Vnn3 vanin 3 JBrowse link 1 22,649,114 22,661,376 RGD:1624291
RGD:13792537
phylloquinone catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:2316273
G Cbr3 carbonyl reductase 3 JBrowse link 11 33,909,417 33,917,674 RGD:2316293
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of cobalamin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clybl citrate lyase beta like JBrowse link 15 108,608,203 108,838,222 RGD:1600115
RGD:1624291
positive regulation of retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:6771354
G Rdh16 retinol dehydrogenase 16 JBrowse link 7 71,058,150 71,072,685 RGD:6771354
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdxk pyridoxal kinase JBrowse link 20 10,930,651 10,952,194 RGD:1600115
RGD:1624291
RGD:13792537
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase JBrowse link 20 10,883,952 10,912,870 RGD:1600115
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdxk pyridoxal kinase JBrowse link 20 10,930,651 10,952,194 RGD:2303018
G Pnpo pyridoxamine 5'-phosphate oxidase JBrowse link 10 84,874,926 84,881,190 RGD:1624291
RGD:13792537
pyridoxal phosphate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdxp pyridoxal phosphatase JBrowse link 7 120,140,460 120,145,908 RGD:1624291
RGD:1600115
pyridoxine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pnpo pyridoxamine 5'-phosphate oxidase JBrowse link 10 84,874,926 84,881,190 RGD:1600115
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
regulation of cobalamin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clybl citrate lyase beta like JBrowse link 15 108,608,203 108,838,222 RGD:1624291
RGD:13792537
RGD:1600115
regulation of vitamin A metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:10400849
G Isx intestine-specific homeobox JBrowse link 19 14,198,899 14,219,269 RGD:1624291
regulation of vitamin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd320 CD320 molecule JBrowse link 7 18,700,445 18,706,244 RGD:1624291
retinoic acid catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crabp1 cellular retinoic acid binding protein 1 JBrowse link 8 59,344,097 59,352,135 RGD:1600115
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:1624291
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 JBrowse link 4 116,261,796 116,278,615 RGD:6771354
RGD:1624291
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 JBrowse link 1 256,369,410 256,380,649 RGD:1624291
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 JBrowse link 12 17,382,749 17,387,909 RGD:1624291
RGD:1600115
riboflavin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rfk riboflavin kinase JBrowse link 1 236,494,221 236,501,733 RGD:1600115
riboflavin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rfk riboflavin kinase JBrowse link 1 236,494,221 236,501,733 RGD:13792537
thiamine metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp3 acid phosphatase 3 JBrowse link 8 112,838,574 112,884,062 RGD:1600115
RGD:1624291
G Thtpa thiamine triphosphatase JBrowse link 15 33,755,157 33,759,117 RGD:1600115
G Tpk1 thiamin pyrophosphokinase 1 JBrowse link 4 72,792,252 73,174,179 RGD:1624291
vitamin A metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrat lecithin retinol acyltransferase JBrowse link 2 181,896,304 181,905,366 RGD:1599829
RGD:1624291
RGD:1599832
RGD:1599831
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:1625187
G Rbp1 retinol binding protein 1 JBrowse link 8 106,449,321 106,470,842 RGD:1624291
RGD:1600115
vitamin D catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:625496
RGD:14995311
RGD:14995316
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:69373
RGD:1624291
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1624291
vitamin D metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calb1 calbindin 1 JBrowse link 5 29,538,380 29,562,774 RGD:68751
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:1298844
RGD:1624291
RGD:734870
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:68680
RGD:1624291
RGD:69372
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 JBrowse link 1 184,060,521 184,106,604 RGD:1624291
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1598934
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:1624291
RGD:1600115
vitamin D3 metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
vitamin E biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pltp phospholipid transfer protein JBrowse link 3 161,304,469 161,322,289 RGD:1624291
vitamin E metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ttpa alpha tocopherol transfer protein JBrowse link 5 34,007,926 34,029,315 RGD:1600435
RGD:13792537
RGD:1624291
vitamin K biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ubiad1 UbiA prenyltransferase domain containing 1 JBrowse link 5 165,247,630 165,259,228 RGD:1600115
RGD:13792537
RGD:1624291
vitamin K metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:1624291
RGD:1600115
G LOC103693015 vitamin K epoxide reductase complex subunit 1-like protein 1 JBrowse link 8 16,287,755 16,337,927 RGD:8553362
RGD:13792537
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:1624291
RGD:13792537
RGD:1600115
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 JBrowse link 12 30,218,825 30,268,990 RGD:8553362
RGD:13792537
RGD:1624291
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      small molecule metabolic process 1789
        vitamin metabolic process 79
          fat-soluble vitamin metabolic process + 34
          negative regulation of vitamin metabolic process + 6
          phylloquinone metabolic process + 2
          positive regulation of vitamin metabolic process + 6
          regulation of vitamin metabolic process + 16
          vitamin biosynthetic process + 21
          vitamin catabolic process + 14
          water-soluble vitamin metabolic process + 39
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.