Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tpk1 (thiamin pyrophosphokinase 1) Rattus norvegicus
Analyze
Symbol: Tpk1
Name: thiamin pyrophosphokinase 1
Description: Predicted to have thiamine diphosphokinase activity. Predicted to be involved in thiamine diphosphate biosynthetic process and thiamine metabolic process. Human ortholog(s) of this gene implicated in inherited metabolic disorder. Orthologous to human TPK1 (thiamin pyrophosphokinase 1); PARTICIPATES IN thiamine metabolic pathway; INTERACTS WITH bisphenol A; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE (ortholog); 1,1-dichloroethene (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC680668; MGC188595; similar to Thiamin pyrophosphokinase 1 (Thiamine pyrophosphokinase 1) (mTPK1); thiamine pyrophosphokinase
Orthologs:
Homo sapiens (human) : TPK1 (thiamin pyrophosphokinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Tpk1 (thiamine pyrophosphokinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpk1 (thiamin pyrophosphokinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TPK1 (thiamin pyrophosphokinase 1)
Canis lupus familiaris (dog) : TPK1 (thiamin pyrophosphokinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpk1 (thiamin pyrophosphokinase 1)
Sus scrofa (pig) : TPK1 (thiamin pyrophosphokinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0472,792,252 - 73,174,179 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04137,495,338 - 137,661,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04137,705,456 - 137,869,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4471,113,965 - 71,521,331 (-)NCBIRGSC3.4rn4RGSC3.4
Celera467,116,073 - 67,485,255 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tpk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589408
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.