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ONTOLOGY REPORT - ANNOTATIONS

Term:vitamin K metabolic process
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Accession:GO:0042373 term browser browse the term
Definition:The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
Synonyms:exact_synonym: vitamin K metabolism
 broad_synonym: naphthoquinone metabolic process;   naphthoquinone metabolism


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vitamin K metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm2 AIF family member 2 involved_in ISO (PMID:35922516) RGD PMID:35922516 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO
ISS		 (PMID:18449627)
GO_REF:0000024		 RGD
UniProt		 PMID:18449627 GO_REF:0000024 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Crcp CGRP receptor component involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225 		JBrowse link
G ENSRNOG00000070855 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:34,016,445...34,017,156 JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in IEA
ISO		 GO_REF:0000107
(PMID:17073445)		 Ensembl
RGD		 PMID:17073445 GO_REF:0000107 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in IDA
ISO		 PMID:8999809
(PMID:8999809)
(MGI:85821|PMID:8999809)		 RGD PMID:8999809 PMID:8999809 MGI:85821, RGD:151356617 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:19492146)
(PMID:15879509)
GO_REF:0000033
(PMID:16270630), (PMID:33154105)
GO_REF:0000002
(MGI:5559848|PMID:19492146)		 UniProt
RGD
GO_Central
InterPro		 PMID:15879509 PMID:16270630 PMID:19492146 PMID:33154105 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 MGI:5559848 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 involved_in ISO
IBA
IEA
IDA		 (PMID:21367861)
(PMID:23928358)
GO_REF:0000033
GO_REF:0000002
(MGI:5559651|PMID:23928358)		 RGD
GO_Central
InterPro		 PMID:21367861 PMID:23928358 PMID:23928358 GO_REF:0000002 GO_REF:0000033 MGI:5559651, RGD:8553362 NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225 		JBrowse link
phylloquinone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 IDA menadione catabolism RGD PMID:16359670 RGD:2316273 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbr3 carbonyl reductase 3 IDA menadione catabolism RGD PMID:18983987 RGD:2316293 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in ISO (PMID:24138531) RGD PMID:24138531 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229 		JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:20953171), (PMID:23169578)		 UniProt
GO_Central
RGD		 PMID:20953171 PMID:23169578 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
vitamin K catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in ISO (PMID:24138531) RGD PMID:24138531 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      metabolic process 12307
        small molecule metabolic process 1905
          cellular ketone metabolic process 252
            vitamin K metabolic process 11
              phylloquinone metabolic process + 3
              vitamin K biosynthetic process + 1
              vitamin K catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      metabolic process 12307
        small molecule metabolic process 1905
          vitamin metabolic process 103
            fat-soluble vitamin metabolic process 45
              vitamin K metabolic process 11
                phylloquinone metabolic process + 3
                vitamin K biosynthetic process + 1
                vitamin K catabolic process + 3
paths to the root