Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

calcitriol biosynthetic process from calciol (GO:0036378)
Annotations: Rat: (4) Mouse: (3) Human: (4) Chinchilla: (3) Bonobo: (4) Dog: (3) Squirrel: (3) Pig: (5)
Parent Terms Term With Siblings Child Terms
1,3-dichloro-2-propanol biosynthetic process 
1,5-anhydro-D-fructose biosynthetic process 
2-deoxystreptamine biosynthetic process 
alditol biosynthetic process +   
butirosin biosynthetic process 
calcitriol biosynthetic process from calciol  
Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.
diol biosynthetic process +   
ergosterol biosynthetic process +  
gentamycin biosynthetic process 
inositol biosynthetic process +   
inositol phosphate biosynthetic process +   
kanamycin biosynthetic process 
negative regulation of vitamin D biosynthetic process +   
neomycin biosynthetic process 
paromomycin biosynthetic process 
phenolic phthiocerol biosynthetic process 
phytosphingosine biosynthetic process  
positive regulation of vitamin D biosynthetic process  
regulation of vitamin D biosynthetic process +   
streptomycin biosynthetic process 
tobramycin biosynthetic process 
vitamin D3 biosynthetic process 
vitamin D3 catabolic process 
vomitoxin biosynthetic process 

Exact Synonyms: calcitriol biosynthesis from calciol ;   vitamin D3 activation
Broad Synonyms: 1alpha,25(OH)2D3 biosynthesis ;   1alpha,25-dihydroxycholecalciferol biosynthesis ;   1alpha,25-dihydroxyvitamin D3 biosynthesis
Definition Sources: GOC:BHF, GOC:rl, PMID:17426122, PMID:20511049

paths to the root