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ONTOLOGY REPORT - ANNOTATIONS

Term:diol biosynthetic process
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Accession:GO:0034312 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
Synonyms:exact_synonym: dihydric alcohol biosynthetic process;   diol anabolism;   diol biosynthesis;   diol formation;   diol synthesis


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diol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx1 epoxide hydrolase 1 IDA RGD PMID:2507189 RGD:11252156 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI:3815115 (MGI:3846467|PMID:19416652) RGD PMID:19416652 MGI:3846467 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1098386|PMID:9363775)
GO_REF:0000107		 RGD
Ensembl		 PMID:9363775 GO_REF:0000107 MGI:1098386 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:26510981)
GO_REF:0000107		 RGD
Ensembl		 PMID:26510981 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Acer1 alkaline ceramidase 1 involved_in ISO
IBA		 (PMID:17713573), (PMID:20207939), (PMID:20628055)
(MGI:5800647|PMID:27126290), (MGI:6107252|PMID:29056331)
PMID:21873635		 RGD PMID:17713573 PMID:20207939 PMID:20628055 PMID:27126290 PMID:29056331 More... MGI:5800647 MGI:6107252, RGD:13792537 NCBI chr 9:1,792,790...1,824,434
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20089856), (PMID:20207939), (PMID:20628055)
(MGI:6116621|PMID:29401619)
PMID:21873635		 RGD PMID:16940153 PMID:20089856 PMID:20207939 PMID:20628055 PMID:29401619 More... MGI:6116621, RGD:13792537 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20068046), (PMID:20207939), (PMID:26792856)
(MGI:5749603|PMID:26474409)		 RGD PMID:20068046 PMID:20207939 PMID:26474409 PMID:26792856 MGI:5749603 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:10610716), (PMID:12815059)
(MGI:1267186|PMID:9653654)		 UniProt
Ensembl
RGD		 PMID:9653654 PMID:10610716 PMID:12815059 GO_REF:0000024 GO_REF:0000107 MGI:1267186 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
ISO
IBA		 PMID:10488143
(PMID:30154232)
PMID:21873635
PMID:15217782
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15123644		 RGD PMID:10652340 PMID:16126722 PMID:16380386 PMID:30154232 PMID:10488143 More... MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838800, RGD:13792537, RGD:13838794, RGD:13838793 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G ENSRNOG00000069695 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr14:25,729,638...25,730,194 JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IBA
IEA		 UniProtKB:Q9NRA0 (PMID:23106337)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:23106337 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA		 UniProtKB:Q9NYA1 (PMID:23106337)
PMID:21873635		 RGD PMID:23106337 PMID:21873635 RGD:13792537 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3815115 (MGI:3814228|PMID:16216550)
(PMID:19416851), (PMID:33558761)
PMID:21873635		 RGD PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:3815117 (MGI:3814228|PMID:16216550)
(PMID:19416851), (PMID:33558761)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 GO_REF:0000107 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in ISO
IBA		 (PMID:19416851)
PMID:21873635		 RGD PMID:19416851 PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in ISO (PMID:19416851), (PMID:33558761) RGD PMID:19416851 PMID:33558761 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B involved_in ISO (PMID:19416851) RGD PMID:19416851 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO (PMID:23707606)
(MGI:5645206|PMID:19666465)		 RGD PMID:19666465 PMID:23707606 MGI:5645206 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in TAS
IEA
IBA
ISO		 GO_REF:0000043
PMID:21873635
(PMID:17101830), (PMID:19666465), (PMID:7678411), (PMID:9445252)		 UniProt
RGD		 PMID:7678411 PMID:9445252 PMID:17101830 PMID:19666465 PMID:12051753 More... GO_REF:0000043, RGD:625450, RGD:13792537 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:8,845,161...8,896,343
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase acts_upstream_of_or_within
involved_in		 TAS
ISO
IEA		 (MGI:1328867|PMID:9894812)
GO_REF:0000041		 RGD
UniProt		 PMID:9894812 PMID:1939130 GO_REF:0000041 MGI:1328867, RGD:68294 NCBI chr 8:50,870,838...50,877,878
Ensembl chr 8:50,870,841...50,877,869 		JBrowse link
G Qdpr quinoid dihydropteridine reductase involved_in TAS
IBA
IMP
IDA		 PMID:21873635
PMID:1898002		 RGD
GO_Central
UniProt		 PMID:3680258 PMID:21873635 PMID:1898002 PMID:9235988 PMID:660556 RGD:729701, RGD:13792537, RGD:8553309, RGD:5128582, RGD:4139903 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Spr sepiapterin reductase involved_in TAS
IBA
IMP		 PMID:21873635 RGD
GO_Central		 PMID:2201030 PMID:21873635 PMID:2179471 RGD:70022, RGD:13792537, RGD:1600056 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
G Spr-ps1 sepiapterin reductase, pseudogene 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:117,689,458...117,693,286
Ensembl chr 4:117,689,458...117,692,891 		JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:8,898,074...8,910,538
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      small molecule metabolic process 1914
        alcohol metabolic process 368
          alcohol biosynthetic process 157
            polyol biosynthetic process 71
              diol biosynthetic process 25
                (+)-secoisolariciresinol biosynthetic process 0
                (-)-secoisolariciresinol biosynthetic process 0
                asperfuranone biosynthetic process + 0
                culmorin biosynthetic process 0
                glycol biosynthetic process + 0
                sphinganine biosynthetic process 2
                sphingosine biosynthetic process 15
                tetrahydrobiopterin biosynthetic process 9
                verruculogen biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      organic substance metabolic process 11752
        organic hydroxy compound metabolic process 567
          alcohol metabolic process 368
            alcohol biosynthetic process 157
              polyol biosynthetic process 71
                diol biosynthetic process 25
                  (+)-secoisolariciresinol biosynthetic process 0
                  (-)-secoisolariciresinol biosynthetic process 0
                  asperfuranone biosynthetic process + 0
                  culmorin biosynthetic process 0
                  glycol biosynthetic process + 0
                  sphinganine biosynthetic process 2
                  sphingosine biosynthetic process 15
                  tetrahydrobiopterin biosynthetic process 9
                  verruculogen biosynthetic process 0
paths to the root