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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of vitamin D biosynthetic process
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Accession:GO:0010957 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).



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negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of IEA
ISO
GO_REF:0000107
(PMID:15947108)
Ensembl
RGD
PMID:15947108 GO_REF:0000107 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:15243130)
Ensembl
RGD
PMID:15243130 GO_REF:0000107 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO
IEA
(PMID:19502595)
GO_REF:0000107
RGD
Ensembl
PMID:19502595 GO_REF:0000107 NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        small molecule metabolic process 1947
          vitamin metabolic process 115
            negative regulation of vitamin metabolic process 6
              negative regulation of vitamin D biosynthetic process 4
                negative regulation of calcidiol 1-monooxygenase activity 0
Path 2
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological process 13403
        regulation of cellular process 13038
          regulation of metabolic process 6791
            regulation of primary metabolic process 5626
              regulation of lipid metabolic process 398
                regulation of steroid metabolic process 133
                  negative regulation of steroid metabolic process 34
                    negative regulation of steroid biosynthetic process 30
                      negative regulation of vitamin D biosynthetic process 4
                        negative regulation of calcidiol 1-monooxygenase activity 0
paths to the root