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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol phosphate biosynthetic process
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Accession:GO:0032958 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms:exact_synonym: inositol phosphate anabolism;   inositol phosphate biosynthesis;   inositol phosphate formation;   inositol phosphate synthesis
 narrow_synonym: myo-inositol phosphate biosynthetic process


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inositol phosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO (PMID:20011604) RGD PMID:20011604 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Ip6k1 inositol hexakisphosphate kinase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,781,957...116,826,152
Ensembl chr 8:116,804,451...116,823,540
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 ISO
IBA
(PMID:11502751)
PMID:21873635
RGD PMID:11502751, PMID:21873635 RGD:13792537 NCBI chr20:5,733,485...5,754,859
Ensembl chr20:5,733,482...5,754,773
JBrowse link
G Ipmk inositol polyphosphate multikinase ISO
IBA
MGI:MGI:3583918 (MGI:MGI:3583505|PMID:15939867)
PMID:21873635
RGD PMID:15939867, PMID:21873635 MGI:MGI:3583505, RGD:13792537 NCBI chr20:18,457,309...18,489,884
Ensembl chr20:18,457,310...18,489,833
JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:15,604,148...15,643,312
Ensembl chr17:15,604,145...15,643,489
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,545,007...111,553,605
Ensembl chr 3:111,545,007...111,553,604
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:98,615,287...98,710,426
Ensembl chr13:98,615,287...98,708,149
JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,018,857...84,040,433
Ensembl chr 1:84,018,859...84,040,433
JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:113,272,850...113,316,324
Ensembl chr 3:113,272,850...113,445,435
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:111,232,967...111,249,613
Ensembl chr 9:111,220,858...111,286,185
JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:16973916 RGD:2299886 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Plcg2 phospholipase C, gamma 2 ISO
IEA
(MGI:MGI:85738|PMID:9013981)
GO_REF:0000107
RGD
Ensembl
PMID:9013981 GO_REF:0000107, MGI:MGI:85738 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Ptafr platelet-activating factor receptor ISO (MGI:MGI:85738|PMID:9013981) RGD PMID:9013981 MGI:MGI:85738 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Scp2 sterol carrier protein 2 ISO (PMID:12641450) RGD PMID:12641450 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487, PMID:7782310 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:248,982,039...250,300,952 JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1r1 ADCYAP receptor type I IDA RGD PMID:8943280 RGD:2315982 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO (PMID:9322919) RGD PMID:9322919 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Cd244 CD244 molecule ISO (PMID:8376943) RGD PMID:8376943 NCBI chr13:89,959,091...89,995,993
Ensembl chr13:89,975,267...89,995,974
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IDA RGD PMID:1332507 RGD:2316794 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11861328 RGD:9743897 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Ptafr platelet-activating factor receptor IDA RGD PMID:8798508 RGD:9999203 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Pth parathyroid hormone ISO (PMID:11604398) RGD PMID:11604398 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Pth1r parathyroid hormone 1 receptor IDA PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Snca synuclein alpha ISO (PMID:15641770) RGD PMID:15641770 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15705806)
Ensembl
UniProt
RGD
PMID:15705806 GO_REF:0000024, GO_REF:0000107 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO
IEA
(MGI:MGI:5318037|PMID:10493819)
GO_REF:0000107
RGD
Ensembl
PMID:10493819 GO_REF:0000107, MGI:MGI:5318037 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G P2ry1 purinergic receptor P2Y1 IDA PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 ISO (PMID:8670200) RGD PMID:8670200 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Pou1f1 POU class 1 homeobox 1 ISO MGI:MGI:1856024|MGI:MGI:1856025 (MGI:MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:MGI:2135699 NCBI chr11:2,645,659...2,662,581
Ensembl chr11:2,645,865...2,662,579
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptk2b protein tyrosine kinase 2 beta ISO
ISS
(MGI:MGI:3583523|PMID:12960403)
GO_REF:0000024
RGD
UniProt
PMID:12960403 GO_REF:0000024, MGI:MGI:3583523 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      organic substance metabolic process 11639
        organic substance biosynthetic process 6116
          organophosphate biosynthetic process 489
            inositol phosphate biosynthetic process 33
              inositol trisphosphate biosynthetic process + 12
              myo-inositol hexakisphosphate biosynthetic process + 0
              negative regulation of inositol phosphate biosynthetic process + 2
              positive regulation of inositol phosphate biosynthetic process + 16
              regulation of inositol phosphate biosynthetic process + 19
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      biosynthetic process 6218
        organic substance biosynthetic process 6116
          organic hydroxy compound biosynthetic process 241
            alcohol biosynthetic process 154
              polyol biosynthetic process 69
                inositol phosphate biosynthetic process 33
                  inositol trisphosphate biosynthetic process + 12
                  myo-inositol hexakisphosphate biosynthetic process + 0
                  negative regulation of inositol phosphate biosynthetic process + 2
                  positive regulation of inositol phosphate biosynthetic process + 16
                  regulation of inositol phosphate biosynthetic process + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.