ONTOLOGY REPORT - ANNOTATIONS
Term: vitamin D biosynthetic process
Accession: GO:0042368
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Definition: The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms: exact_synonym: vitamin D anabolism; vitamin D biosynthesis; vitamin D formation; vitamin D synthesis
narrow_synonym: calciferol biosynthesis; calciferol biosynthetic process; cholecalciferol biosynthesis; cholecalciferol biosynthetic process; ergocalciferol biosynthesis; ergocalciferol biosynthetic process
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
involved_in
IBA IEA ISO
PMID:21873635 GO_REF:0000107 (PMID:15465040)
Ensembl RGD
PMID:15465040 PMID:21873635
GO_REF:0000107, RGD:13792537
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
involved_in
ISO IEA IBA
(PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400) GO_REF:0000107 (MGI:3590419|PMID:15972816) PMID:21873635
RGD Ensembl
PMID:9415400 PMID:15795327 PMID:15972816 PMID:16549446 PMID:17023519 PMID:22862690 PMID:21873635 More...
GO_REF:0000107 MGI:3590419 , RGD:13792537
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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Cyp2r1
cytochrome P450, family 2, subfamily r, polypeptide 1
involved_in acts_upstream_of_or_within
ISO
(PMID:15465040), (PMID:18511070) (MGI:2677973|PMID:12867411)
RGD
PMID:12867411 PMID:15465040 PMID:18511070
MGI:2677973
NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
involved_in
IEA
GO_REF:0000108
GOC
GO_REF:0000108
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
involved_in
ISO IEA
(PMID:16549446) GO_REF:0000107
RGD Ensembl
PMID:16549446
GO_REF:0000107
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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Gfi1
growth factor independent 1 transcriptional repressor
involved_in
ISO
(PMID:15947108)
RGD
PMID:15947108
NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
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Nfkb1
nuclear factor kappa B subunit 1
involved_in
ISO
(PMID:15243130)
RGD
PMID:15243130
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Snai1
snail family transcriptional repressor 1
involved_in
ISO
(PMID:19502595)
RGD
PMID:19502595
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snai2
snail family transcriptional repressor 2
involved_in
ISO
(PMID:18485278), (PMID:19502595)
RGD
PMID:18485278 PMID:19502595
NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
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Ifng
interferon gamma
involved_in
ISO
(PMID:9282826)
RGD
PMID:9282826
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Tnf
tumor necrosis factor
involved_in
ISO
(PMID:1690216)
RGD
PMID:1690216
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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