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ONTOLOGY REPORT - ANNOTATIONS

Term:vitamin D biosynthetic process
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Accession:GO:0042368 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms:exact_synonym: vitamin D anabolism;   vitamin D biosynthesis;   vitamin D formation;   vitamin D synthesis
 narrow_synonym: calciferol biosynthesis;   calciferol biosynthetic process;   cholecalciferol biosynthesis;   cholecalciferol biosynthetic process;   ergocalciferol biosynthesis;   ergocalciferol biosynthetic process


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISO
IEA
IBA 		(PMID:15465040)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15465040 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA
IBA 		(PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
GO_REF:0000107
(PMID:15972816)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:9415400 PMID:15795327 PMID:15972816 PMID:16549446 PMID:17023519 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 involved_in ISO
IEA 		(PMID:15465040), (PMID:18511070)
GO_REF:0000107 		RGD
Ensembl		 PMID:15465040 PMID:18511070 GO_REF:0000107 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor acts_upstream_of IEA
ISO 		GO_REF:0000107
(PMID:15947108) 		Ensembl
RGD		 PMID:15947108 GO_REF:0000107 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15243130) 		Ensembl
RGD		 PMID:15243130 GO_REF:0000107 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO
IEA 		(PMID:19502595)
GO_REF:0000107 		RGD
Ensembl		 PMID:19502595 GO_REF:0000107 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:9282826) RGD PMID:9282826 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA 		(PMID:1690216)
GO_REF:0000107 		RGD
Ensembl		 PMID:1690216 GO_REF:0000107 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        biosynthetic process 8630
          lipid biosynthetic process 751
            steroid biosynthetic process 194
              vitamin D biosynthetic process 11
                calcitriol biosynthetic process from calciol 5
                negative regulation of vitamin D biosynthetic process 4
                positive regulation of vitamin D biosynthetic process 2
                regulation of vitamin D biosynthetic process + 6
                vitamin D3 biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          lipid metabolic process 1485
            steroid metabolic process 374
              steroid biosynthetic process 194
                vitamin D biosynthetic process 11
                  calcitriol biosynthetic process from calciol 5
                  negative regulation of vitamin D biosynthetic process 4
                  positive regulation of vitamin D biosynthetic process 2
                  regulation of vitamin D biosynthetic process + 6
                  vitamin D3 biosynthetic process 0
paths to the root