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ONTOLOGY REPORT - ANNOTATIONS

Term:L-ascorbic acid metabolic process
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Accession:GO:0019852 term browser browse the term
Definition:The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
Synonyms:exact_synonym: L-ascorbic acid metabolism;   ascorbate metabolic process;   ascorbate metabolism;   vitamin C metabolic process;   vitamin C metabolism
 xref: Reactome:R-HSA-196836 "Vitamin C (ascorbate) metabolism"


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L-ascorbic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:88107 (PMID:33544780) 		Ensembl
RGD		 PMID:33544780 GO_REF:0000107 NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:88106 (PMID:33544780) RGD PMID:33544780 NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:89,700,649...89,729,825 		JBrowse link
G Clstn3 calsyntenin 3 involved_in ISO (PMID:34673103)
(PMID:33672967) 		RGD PMID:33672967 PMID:34673103 NCBI chr 4:159,017,795...159,051,069
Ensembl chr 4:159,017,795...159,051,069 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:28106121) 		Ensembl
RGD		 PMID:28106121 GO_REF:0000107 NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2429419 (PMID:11118286) 		Ensembl
RGD		 PMID:11118286 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO
IEA
IBA
ISS 		(PMID:11511179)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
UniProt
Ensembl
GO_Central		 PMID:11511179 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISO
IEA
IBA
ISS 		(PMID:15970797)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024 		RGD
UniProt
GO_Central
Ensembl		 PMID:15970797 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:256,673,376...256,695,154
Ensembl chr 1:256,673,274...256,695,146 		JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:27085842 RGD:26884454 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759 		JBrowse link
G Selenon selenoprotein N acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:28106121) 		Ensembl
RGD		 PMID:28106121 GO_REF:0000107 NCBI chr 5:152,032,330...152,046,707
Ensembl chr 5:152,032,330...152,046,707 		JBrowse link
G Slc23a2 solute carrier family 23 member 2 IMP RGD PMID:10331392 RGD:634186 NCBI chr 3:139,755,583...139,913,304
Ensembl chr 3:139,755,584...139,847,343 		JBrowse link
L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within 		IMP
IEA
ISO 		PMID:22820017
GO_REF:0000107
GO_REF:0000117
(PMID:20410296)
(PMID:15769935) 		Ensembl
UniProt
RGD		 PMID:15769935 PMID:20410296 PMID:22820017 GO_REF:0000107 GO_REF:0000117, RGD:13825440 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167 		JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in ISS
IEA 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000043 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422 		JBrowse link
G Rgn regucalcin involved_in ISS
IBA
IEA
ISO 		GO_REF:0000024
GO_REF:0000033
GO_REF:0000043
(PMID:23349732) 		UniProt
GO_Central
RGD		 PMID:23349732 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:4,172,537...4,190,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        lactone metabolic process 16
          L-ascorbic acid metabolic process 13
            L-ascorbic acid biosynthetic process + 4
            L-ascorbic acid catabolic process 0
            ascorbate glutathione cycle 0
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        small molecule metabolic process 1860
          organic acid metabolic process 1032
            oxoacid metabolic process 1022
              carboxylic acid metabolic process 1008
                L-ascorbic acid metabolic process 13
                  L-ascorbic acid biosynthetic process + 4
                  L-ascorbic acid catabolic process 0
                  ascorbate glutathione cycle 0
paths to the root