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ONTOLOGY REPORT - ANNOTATIONS


Term:L-ascorbic acid metabolic process
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Accession:GO:0019852 term browser browse the term
Definition:The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
Synonyms:exact_synonym: L-ascorbic acid metabolism;   ascorbate metabolic process;   ascorbate metabolism;   vitamin C metabolic process;   vitamin C metabolism


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L-ascorbic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:2429419 (MGI:1928560|PMID:11118286) RGD PMID:11118286 MGI:1928560 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:11511179)
Ensembl
UniProt
RGD
PMID:11511179 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISO
ISS
(PMID:15970797)
GO_REF:0000024
RGD
UniProt
PMID:15970797 GO_REF:0000024 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:27085842 RGD:26884454 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Slc23a2 solute carrier family 23 member 2 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:10331392 PMID:21873635 RGD:634186, RGD:13792537 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
L-ascorbic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in
acts_upstream_of_or_within
IMP
ISO
PMID:22820017
(MGI:4834110|PMID:20410296)
(MGI:3588122|PMID:15769935)
RGD PMID:15769935 PMID:20410296 PMID:22820017 MGI:3588122 MGI:4834110, RGD:13825440 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Gsto1 glutathione S-transferase omega 1 IMP RGD PMID:9786866 RGD:70644 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gulo gulonolactone (L-) oxidase involved_in ISS
IEA
GO_REF:0000024
GO_REF:0000041
UniProt GO_REF:0000024 GO_REF:0000041 NCBI chr15:40,205,677...40,227,766
Ensembl chr15:40,205,665...40,227,874
JBrowse link
G Rgn regucalcin involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5486063|PMID:23349732)
GO_REF:0000024
RGD
UniProt
PMID:23349732 PMID:21873635 GO_REF:0000024 MGI:5486063, RGD:13792537 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      small molecule metabolic process 1791
        monosaccharide metabolic process 279
          L-ascorbic acid metabolic process 8
            L-ascorbic acid biosynthetic process + 4
            L-ascorbic acid catabolic process 0
            ascorbate glutathione cycle 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular metabolic process 10721
        organic acid metabolic process 1011
          oxoacid metabolic process 979
            carboxylic acid metabolic process 960
              L-ascorbic acid metabolic process 8
                L-ascorbic acid biosynthetic process + 4
                L-ascorbic acid catabolic process 0
                ascorbate glutathione cycle 0
paths to the root