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ONTOLOGY REPORT - ANNOTATIONS

Term:neuroinflammatory response
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Accession:GO:0150076 term browser browse the term
Definition:The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.
Synonyms:exact_synonym: nerve tissue inflammatory response;   nervous tissue inflammatory response;   neural tissue inflammatory response


show annotations for term's descendants           Sort by:
neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 involved_in ISO (PMID:12441059) RGD PMID:12441059 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:12441059)		 Ensembl
UniProt
RGD		 PMID:12441059 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Bpgm bisphosphoglycerate mutase acts_upstream_of_or_within ISO MGI:6506869 (PMID:32966787) RGD PMID:32966787 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit acts_upstream_of_or_within ISO (PMID:34992132) RGD PMID:34992132 NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350 		JBrowse link
G Ifng interferon gamma involved_in IDA PMID:27235345 ARUK-UCL PMID:27235345 RGD:14401572 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il4 interleukin 4 involved_in IDA PMID:27235345 ARUK-UCL PMID:27235345 RGD:14401572 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO MGI:2444304 (PMID:33941276) RGD PMID:33941276 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:26607664) RGD PMID:26607664 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29890290)		 Ensembl
RGD		 PMID:29890290 GO_REF:0000107 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:21206757) RGD PMID:21206757 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29859094) RGD PMID:29859094 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO MGI:4362969 (PMID:29034508) RGD PMID:29034508 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A acts_upstream_of_or_within ISO MGI:96892 (PMID:33941276) RGD PMID:33941276 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:29890290)		 Ensembl
RGD		 PMID:29890290 GO_REF:0000107 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP RGD PMID:12838511 RGD:1625689 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 UniProtKB:P05067 (PMID:15457210)
GO_REF:0000107		 RGD
Ensembl		 PMID:15457210 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2136636 (PMID:9734405) RGD PMID:9734405 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:P49768|UniProtKB:Q15109 (PMID:15457210), (PMID:20445063)
(PMID:18723082)		 RGD PMID:15457210 PMID:18723082 PMID:20445063 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bace2 beta-secretase 2 IEP RGD PMID:21073551 RGD:13782176 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G C1qa complement C1q A chain involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067 (PMID:15269255)		 Ensembl
RGD		 PMID:15269255 GO_REF:0000107 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO UniProtKB:P05067 (PMID:19561098) RGD PMID:19561098 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Cntf ciliary neurotrophic factor involved_in IDA
IBA		 spinal cord astrocytes
GO_REF:0000033		 GO_Central
RGD		 PMID:11771938 GO_REF:0000033, RGD:1626172 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:16837601 RGD:1581900 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18375019)
UniProtKB:P05067 (PMID:20368278)		 RGD PMID:18375019 PMID:20368278 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P05067 (PMID:17255335) RGD PMID:17255335 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Il1b interleukin 1 beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:28377412)		 Ensembl
RGD		 PMID:28377412 GO_REF:0000107 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mt2A metallothionein 2A IEP RGD PMID:19837066 RGD:6483825 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:26607664) RGD PMID:26607664 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Psen1 presenilin 1 involved_in ISO UniProtKB:P05067 (PMID:20445063) RGD PMID:20445063 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176256 (PMID:23680462)		 Ensembl
RGD		 PMID:23680462 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO UniProtKB:P10636 (PMID:29073081) RGD PMID:29073081 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IDA RGD PMID:34852714 RGD:155882542 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
astrocyte activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO
IEA		 UniProtKB:A0A0R4J0I9|UniProtKB:P49768 (PMID:23152628)
GO_REF:0000107		 RGD
Ensembl		 PMID:23152628 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(PMID:20026663)		 UniProt
RGD		 PMID:20026663 GO_REF:0000024 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (PMID:23152628) RGD PMID:23152628 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Psen1 presenilin 1 involved_in ISO UniProtKB:A0A0R4J0I9|UniProtKB:P05067 (PMID:23152628) RGD PMID:23152628 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
glial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc9a6 solute carrier family 9 member A6 IMP RGD PMID:34928329 RGD:151664747 NCBI chr  X:134,430,677...134,486,747
Ensembl chr  X:134,420,756...134,485,375 		JBrowse link
microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 UniProtKB:P05067 (PMID:15457210)
UniProtKB:P05067 (PMID:22406537)
GO_REF:0000107		 RGD
Ensembl		 PMID:15457210 PMID:22406537 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G App amyloid beta precursor protein involved_in ISO
IEA		 UniProtKB:Q15109|UniProtKB:Q62151 (PMID:15457210), (PMID:22406537)
(PMID:18723082)
GO_REF:0000107		 RGD
Ensembl		 PMID:15457210 PMID:18723082 PMID:22406537 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G C1qa complement C1q A chain involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (PMID:15269255)		 Ensembl
RGD		 PMID:15269255 GO_REF:0000107 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO UniProtKB:P05067 (PMID:19561098) RGD PMID:19561098 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Casp1 caspase 1 IMP RGD PMID:15149850 RGD:2315925 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15857407)		 Alzheimers_University_of_Toronto
Ensembl
RGD		 PMID:15857407 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33841088 RGD:151665762 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IDA PMID:11870871 RGD
ARUK-UCL		 PMID:20018408 PMID:11870871 RGD:9491804, RGD:4892001 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IMP RGD PMID:24447880 RGD:9491776 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Ifng interferon gamma involved_in ISO
IGI		 ComplexPortal:CPX-1062|UniProtKB:P05067|UniProtKB:P10636|UniProtKB:P49768 (PMID:19808651), (PMID:7715705)
ComplexPortal:CPX-1062|UniProtKB:P05067|UniProtKB:P49768 (PMID:20368278), (PMID:26227742), (PMID:7715705)
PMID:27094552		 RGD PMID:7715705 PMID:19808651 PMID:20368278 PMID:26227742 PMID:27094552 RGD:14397550 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P05067 (PMID:17255335) RGD PMID:17255335 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ifngr2 interferon gamma receptor 2 involved_in IGI PMID:27094552 ARUK-UCL PMID:27094552 RGD:14397550 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Il13 interleukin 13 IMP RGD PMID:19752235 RGD:8549634 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il4 interleukin 4 IDA RGD PMID:23786632 RGD:8142387 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:18981141) RGD PMID:18981141 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO UniProtKB:P01580 (PMID:26227742) RGD PMID:26227742 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:2445420 (PMID:15233917) RGD PMID:15233917 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:3720053 (PMID:29540778) RGD PMID:29540778 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:26607664) RGD PMID:26607664 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IMP RGD PMID:28528966 RGD:13781879 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G P2ry1 purinergic receptor P2Y1 NOT|involved_in IMP PMID:11245682 ARUK-UCL PMID:11245682 RGD:13673788 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry2 purinergic receptor P2Y2 NOT|involved_in IMP PMID:11245682 ARUK-UCL PMID:11245682 RGD:13673788 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:2389489 (PMID:17035541) RGD PMID:17035541 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tlr1 toll-like receptor 1 IDA RGD PMID:16973131 RGD:1643119 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:16973131 RGD:1643119 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 IDA RGD PMID:16973131 RGD:1643119 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 IDA RGD PMID:16973131 RGD:1643119 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 IDA RGD PMID:16973131 RGD:1643119 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr9 toll-like receptor 9 IDA RGD PMID:16973131 RGD:1643119 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:22950459) RGD PMID:22950459 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO ComplexPortal:CPX-1120|UniProtKB:P10636 (PMID:28592261), (PMID:28802038), (PMID:29073081), (PMID:29518356), (PMID:29663649) RGD PMID:28592261 PMID:28802038 PMID:29073081 PMID:29518356 PMID:29663649 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:19385063 RGD:2316194 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
microglial cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16732273)		 UniProt
RGD		 PMID:16732273 GO_REF:0000024 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(PMID:20026663)		 UniProt
RGD		 PMID:20026663 GO_REF:0000024 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Il33 interleukin 33 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21349253)		 Ensembl
RGD		 PMID:21349253 GO_REF:0000107 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30232263) RGD PMID:30232263 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO		 GO_REF:0000033
(PMID:25690660)		 GO_Central
RGD		 PMID:25690660 GO_REF:0000033 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
negative regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (PMID:20005821)		 Ensembl
RGD		 PMID:20005821 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:30792350)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:30792350 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460) RGD PMID:29407460 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst7 cystatin F involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5910746 (PMID:28251676)		 GO_Central
RGD		 PMID:28251676 GO_REF:0000033 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IDA PMID:19627440 ARUK-UCL PMID:19627440 RGD:13673772 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(PMID:23041626)		 UniProt
RGD		 PMID:23041626 GO_REF:0000024 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (PMID:20005821)		 Ensembl
RGD		 PMID:20005821 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:30792350)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30792350 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO RNAcentral:URS000024A59E_10090 (PMID:30412727) RGD PMID:30412727 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Syt11 synaptotagmin 11 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28686317)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28686317 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25595455)		 GO_Central
RGD		 PMID:25595455 GO_REF:0000033 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019 		JBrowse link
negative regulation of neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd200 Cd200 molecule involved_in IGI
ISO
IBA		 PMID:18164423
(PMID:11099416)
GO_REF:0000033		 RGD
GO_Central		 PMID:11099416 PMID:18164423 GO_REF:0000033, RGD:13792521 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cd200l1 CD200 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:55,350,433...55,401,528
Ensembl chr11:55,336,109...55,401,373 		JBrowse link
G Cd200r1 CD200 receptor 1 involved_in IGI PMID:18164423 ARUK-UCL PMID:18164423 RGD:13792521 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285 		JBrowse link
G Ifnb1 interferon beta 1 IDA RGD PMID:12973019 RGD:401851924 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107		 RGD
Ensembl		 PMID:27277332 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30792350)		 UniProt
RGD		 PMID:30792350 GO_REF:0000024 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO RNAcentral:URS000024A59E_10090 (PMID:30412727) RGD PMID:30412727 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IBA
ISO		 GO_REF:0000033
(PMID:27147664)		 GO_Central
RGD		 PMID:27147664 GO_REF:0000033 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:32514138)
(PMID:29407460), (PMID:31134514), (PMID:31900229)		 RGD PMID:29407460 PMID:31134514 PMID:31900229 PMID:32514138 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33841088 RGD:151665762 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
positive regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsc cathepsin C acts_upstream_of_or_within ISO (PMID:28251676) RGD PMID:28251676 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:21750563 RGD:329955444 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:22302802 RGD:13462052 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:25049354)		 Ensembl
RGD		 PMID:25049354 GO_REF:0000107 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (PMID:19100238) RGD PMID:19100238 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Tafa3 TAFA chemokine like family member 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25595455)		 GO_Central
RGD		 PMID:25595455 GO_REF:0000033 NCBI chr 2:192,264,153...192,280,356
Ensembl chr 2:192,267,093...192,274,019 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IBA		 (PMID:24990881)
GO_REF:0000033
(PMID:24990881), (PMID:25631124), (PMID:29752066), (PMID:30617257), (PMID:31370707)		 RGD
GO_Central		 PMID:24990881 PMID:25631124 PMID:29752066 PMID:30617257 PMID:31370707 GO_REF:0000033 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Ttbk1 tau tubulin kinase 1 involved_in ISO (PMID:19118186) RGD PMID:19118186 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774 		JBrowse link
positive regulation of neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir206 microRNA 206 involved_in ISO (PMID:27277332) RGD PMID:27277332 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IMP
ISO		 PMID:25049354
(PMID:25049354)		 RGD PMID:25049354 PMID:25049354 RGD:13792525 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISS
ISO		 GO_REF:0000024
(PMID:16374777)		 UniProt
RGD		 PMID:16374777 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA		 (PMID:32514138)
GO_REF:0000107		 RGD
Ensembl		 PMID:32514138 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:25631124) RGD PMID:25631124 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
reactive gliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnat2 G protein subunit alpha transducin 2 acts_upstream_of_or_within ISO MGI:6163746 (PMID:23580486) RGD PMID:23580486 NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within_negative_effect		 IEA
ISO		 GO_REF:0000107
(PMID:25716834)		 Ensembl
RGD		 PMID:25716834 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO (PMID:30315808) RGD PMID:30315808 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 acts_upstream_of_or_within ISO MGI:1856965 (PMID:21970971) RGD PMID:21970971 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Myo5a myosin VA IMP RGD PMID:22639889 RGD:42722007 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Pomgnt1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3623521 (PMID:21970971)		 Ensembl
RGD		 PMID:21970971 GO_REF:0000107 NCBI chr 5:129,634,274...129,644,150
Ensembl chr 5:129,634,294...129,644,149 		JBrowse link
G Pomt2 protein-O-mannosyltransferase 2 acts_upstream_of_or_within ISO MGI:5302103 (PMID:21970971) RGD PMID:21970971 NCBI chr 6:106,755,462...106,794,849
Ensembl chr 6:106,755,462...106,794,849 		JBrowse link
regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase IMP RGD PMID:28007901 RGD:12879399 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:34433553)		 UniProt
RGD		 PMID:34433553 GO_REF:0000024 NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IMP rat gene in mouse model RGD PMID:17473852 RGD:5688754 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29662056)		 UniProt
RGD		 PMID:29662056 GO_REF:0000024 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
regulation of neuroinflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd200 Cd200 molecule involved_in IGI PMID:10981966 ARUK-UCL PMID:10981966 RGD:61663 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cd200r1 CD200 receptor 1 involved_in IGI PMID:10981966 ARUK-UCL PMID:10981966 RGD:61663 NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285 		JBrowse link
G Cd200r1l CD200 receptor 1-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:55,842,632...55,860,914
Ensembl chr11:55,842,634...55,885,680 		JBrowse link
G Dagla diacylglycerol lipase, alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:26779719)		 UniProt
RGD		 PMID:26779719 GO_REF:0000024 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29662056)		 UniProt
RGD		 PMID:29662056 GO_REF:0000024 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
ISO
IMP		 GO_REF:0000024
(PMID:29662056)
PMID:28284343		 UniProt
RGD		 PMID:29662056 PMID:28284343 GO_REF:0000024, RGD:14397556 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:Q9Z0D9 (PMID:28052249) RGD PMID:28052249 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    response to stimulus 10793
      response to stress 4260
        defense response 1917
          inflammatory response 878
            neuroinflammatory response 91
              glial cell activation + 63
              negative regulation of neuroinflammatory response + 15
              positive regulation of neuroinflammatory response + 12
              reactive gliosis 7
              regulation of neuroinflammatory response + 32
paths to the root