CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: gold atom
Accession: CHEBI:29287
browse the term
Definition: A copper group element atom that has formula Au.
Synonyms: related_synonym: 79Au; Au; Formula=Au; Gold; InChI=1S/Au; InChIKey=PCHJSUWPFVWCPO-UHFFFAOYSA-N; SMILES=[Au]; aurum; or; oro
xref: CAS:7440-57-5
xref_mesh: MESH:D006046
xref: WebElements:Au
G
Aass
aminoadipate-semialdehyde synthase
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of AASS mRNA Gold analog results in decreased expression of AASS mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
G
Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
ISO
Gold analog results in increased expression of ABCB1 mRNA
CTD
PMID:36057382
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Abcb4
ATP binding cassette subfamily B member 4
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA Gold analog results in decreased expression of ABCB4 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
G
Abcc1
ATP binding cassette subfamily C member 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ABCC1 mRNA
CTD
PMID:28433809
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
G
Abcc2
ATP binding cassette subfamily C member 2
increases expression
ISO
Gold analog results in increased expression of ABCC2 mRNA
CTD
PMID:36057382
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ABL1 mRNA
CTD
PMID:28433809
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
G
Acaa1a
acetyl-CoA acyltransferase 1A
decreases expression
ISO
Gold analog results in decreased expression of ACAA1 mRNA
CTD
PMID:36057382
NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
G
Acaca
acetyl-CoA carboxylase alpha
decreases expression
ISO
Gold analog results in decreased expression of ACACA mRNA
CTD
PMID:36057382
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
G
Acad11
acyl-CoA dehydrogenase family, member 11
decreases expression
ISO
Gold analog results in decreased expression of ACAD11 mRNA
CTD
PMID:36057382
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
G
Acadm
acyl-CoA dehydrogenase medium chain
decreases expression
ISO
Gold analog results in decreased expression of ACADM mRNA
CTD
PMID:36057382
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
G
Acads
acyl-CoA dehydrogenase short chain
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ACADS mRNA
CTD
PMID:28433809
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
G
Acadvl
acyl-CoA dehydrogenase, very long chain
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ACADVL mRNA
CTD
PMID:28433809
NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
G
Aco1
aconitase 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of ACO1 mRNA
CTD
PMID:28433809
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
G
Aco2
aconitase 2
decreases expression multiple interactions
ISO
Gold analog results in decreased expression of ACO2 protein [Polyethyleneimine binds to Gold] which results in increased expression of ACO2 mRNA
CTD
PMID:24780912 PMID:28433809
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
G
Acox1
acyl-CoA oxidase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ACOX1 mRNA
CTD
PMID:19695318
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
G
Acox2
acyl-CoA oxidase 2
decreases expression
ISO
Gold analog results in decreased expression of ACOX2 mRNA
CTD
PMID:36057382
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
G
Acp1
acid phosphatase 1
decreases expression
ISO
Gold results in decreased expression of ACP1 mRNA
CTD
PMID:25523186
NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
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Acvr1c
activin A receptor type 1C
decreases expression
ISO
Gold results in decreased expression of ACVR1C mRNA
CTD
PMID:25523186
NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
G
Adam28
ADAM metallopeptidase domain 28
increases expression
ISO
Gold results in increased expression of ADAM28 mRNA
CTD
PMID:29705079
NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
G
Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
decreases expression
ISO
Gold results in decreased expression of ADH5 mRNA
CTD
PMID:25523186
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
G
Adipor2
adiponectin receptor 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ADIPOR2 mRNA
CTD
PMID:19695318
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
G
Adra1b
adrenoceptor alpha 1B
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of ADRA1B mRNA
CTD
PMID:19695318
NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
G
Adrb2
adrenoceptor beta 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of ADRB2 mRNA
CTD
PMID:19695318
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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Ahsg
alpha-2-HS-glycoprotein
decreases expression
ISO
Gold analog results in decreased expression of AHSG mRNA
CTD
PMID:36057382
NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
increases expression
ISO
Gold results in increased expression of AIFM1 protein
CTD
PMID:25462594
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
G
Aimp1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
decreases expression
ISO
Gold results in decreased expression of AIMP1 mRNA
CTD
PMID:25523186
NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
G
Ak3
adenylate kinase 3
decreases expression
ISO
Gold results in decreased expression of AK3 mRNA
CTD
PMID:25523186
NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
G
Akap13
A-kinase anchoring protein 13
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of AKAP13 mRNA
CTD
PMID:19695318
NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
G
Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
Gold results in increased expression of AKR1B10 mRNA
CTD
PMID:29705079
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
G
Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
Gold results in increased expression of AKR1C2 mRNA
CTD
PMID:29705079
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
G
Akr1c3
aldo-keto reductase family 1, member C3
increases expression
ISO
Gold results in increased expression of AKR1C3 mRNA
CTD
PMID:29705079
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of AKT1 protein
CTD
PMID:27470402
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
G
Alb
albumin
multiple interactions increases expression
ISO
ALB protein results in increased uptake of [Polyethylene Glycols binds to Gold]; ALB protein results in increased uptake of [Polyethyleneimine binds to Gold]; ALB protein results in increased uptake of [Thioctic Acid binds to Gold] Gold analog results in increased expression of ALB mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Anxa5
annexin A5
increases expression
ISO
Gold analog results in increased expression of ANXA5 protein
CTD
PMID:24780912
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
G
Apaf1
apoptotic peptidase activating factor 1
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein Gold analog results in decreased expression of APAF1 mRNA
CTD
PMID:27470402 PMID:28433809 PMID:36057382
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
G
Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
decreases expression
ISO
Gold analog results in decreased expression of APEX1 mRNA
CTD
PMID:36057382
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
G
Apoa4
apolipoprotein A4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of APOA4 mRNA
CTD
PMID:19695318
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
G
Aprt
adenine phosphoribosyl transferase
decreases expression
ISO
Gold analog results in decreased expression of APRT protein
CTD
PMID:24780912
NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431
G
Aqp4
aquaporin 4
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of AQP4 mRNA
CTD
PMID:28433809
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
G
Arl1
ADP-ribosylation factor like GTPase 1
decreases expression
ISO
Gold results in decreased expression of ARL1 mRNA
CTD
PMID:25523186
NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
G
Arl5b
ADP-ribosylation factor like GTPase 5B
decreases expression
ISO
Gold results in decreased expression of ARL5B mRNA
CTD
PMID:25523186
NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
G
Arsg
arylsulfatase G
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ARSG mRNA
CTD
PMID:19695318
NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
G
Asah1
N-acylsphingosine amidohydrolase 1
decreases expression
ISO
Gold analog results in decreased expression of ASAH1 mRNA
CTD
PMID:36057382
NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
G
Atf1
activating transcription factor 1
decreases expression
ISO
Gold results in decreased expression of ATF1 mRNA
CTD
PMID:25523186
NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
G
Atf4
activating transcription factor 4
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ATF4 mRNA
CTD
PMID:28433809
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
G
Atf6
activating transcription factor 6
increases cleavage
ISO
Gold analog results in increased cleavage of ATF6 protein
CTD
PMID:26551149
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
G
Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
decreases expression
ISO
Gold analog results in decreased expression of ATIC protein
CTD
PMID:24780912
NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
G
Atl2
atlastin GTPase 2
decreases expression
ISO
Gold results in decreased expression of ATL2 mRNA
CTD
PMID:25523186
NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421
G
Atm
ATM serine/threonine kinase
decreases expression
ISO
Gold analog results in decreased expression of ATM mRNA
CTD
PMID:36057382
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
G
Atp2b1
ATPase plasma membrane Ca2+ transporting 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ATP2B1 mRNA
CTD
PMID:19695318
NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
G
Atp5f1b
ATP synthase F1 subunit beta
multiple interactions
ISO
Gold analog results in increased expression of and results in decreased phosphorylation of ATP5F1B protein
CTD
PMID:24780912
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
G
Atp6v1g2
ATPase H+ transporting V1 subunit G2
decreases expression
ISO
Gold analog results in decreased expression of ATP6V1G2 mRNA
CTD
PMID:36057382
NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481
G
Atr
ATR serine/threonine kinase
decreases expression
ISO
Gold analog results in decreased expression of ATR mRNA
CTD
PMID:36057382
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
G
Bace1
beta-secretase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of BACE1 mRNA
CTD
PMID:19695318
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
G
Bad
BCL2-associated agonist of cell death
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in increased expression of BAD protein
CTD
PMID:27470402
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
G
Baiap2
BAR/IMD domain containing adaptor protein 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of BAIAP2 mRNA
CTD
PMID:19695318
NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
G
Bak1
BCL2-antagonist/killer 1
increases expression
ISO
Gold results in increased expression of BAK1 mRNA
CTD
PMID:22178767
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of BAX protein; [Gold analog co-treated with Platinum] results in increased expression of BAX mRNA; [Polyethyleneimine binds to Gold] which results in decreased expression of BAX mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of BAX protein [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of BAX protein Gold results in increased expression of BAX mRNA
CTD
PMID:21621595 PMID:22178767 PMID:25846798 PMID:27470402 PMID:27836789 PMID:28433809 More...
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcas2
BCAS2, pre-mRNA processing factor
decreases expression
ISO
Gold results in decreased expression of BCAS2 mRNA
CTD
PMID:25523186
NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO EXP
[Gold analog co-treated with Platinum] results in decreased expression of BCL2 mRNA; [Quercetin analog co-treated with Gold analog] results in decreased expression of BCL2 protein [Gold binds to NKCT1 protein, Naja kaouthia] which results in decreased expression of BCL2 protein
CTD
PMID:25846798 PMID:27470402 PMID:27836789
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bcl2l1
Bcl2-like 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of BCL2L1 mRNA
CTD
PMID:28433809
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
G
Bcl2l11
Bcl2-like 11
decreases expression
ISO
Gold analog results in decreased expression of BCL2L11 mRNA
CTD
PMID:36057382
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
G
Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
Gold results in decreased expression of BIRC2 mRNA
CTD
PMID:25523186
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
G
Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
Gold analog results in decreased expression of BIRC3 mRNA; Gold results in decreased expression of BIRC3 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
G
Bmal1
basic helix-loop-helix ARNT like 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of BMAL1 mRNA
CTD
PMID:19695318
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
G
Bmi1
BMI1 proto-oncogene, polycomb ring finger
decreases expression
ISO
Gold results in decreased expression of BMI1 mRNA
CTD
PMID:25523186
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
G
Brca1
BRCA1, DNA repair associated
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of BRCA1 mRNA Gold analog results in decreased expression of BRCA1 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
G
Brca2
BRCA2, DNA repair associated
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of BRCA2 mRNA Gold analog results in decreased expression of BRCA2 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
G
Bves
blood vessel epicardial substance
increases expression
ISO
Gold results in increased expression of BVES mRNA
CTD
PMID:29705079
NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
G
C1d
C1D nuclear receptor corepressor
decreases expression
ISO
Gold results in decreased expression of C1D mRNA
CTD
PMID:25523186
NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
G
C3
complement C3
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of C3 mRNA
CTD
PMID:28433809
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
G
C8h11orf54
similar to human chromosome 11 open reading frame 54
decreases expression
ISO
Gold results in decreased expression of C11ORF54 mRNA
CTD
PMID:25523186
NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
G
C9
complement C9
decreases expression
ISO
Gold analog results in decreased expression of C9 mRNA
CTD
PMID:36057382
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
G
Capza2
capping actin protein of muscle Z-line subunit alpha 2
decreases expression
ISO
Gold results in decreased expression of CAPZA2 mRNA
CTD
PMID:25523186
NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
G
Car13
carbonic anhydrase 13
decreases expression
ISO
Gold results in decreased expression of CA13 mRNA
CTD
PMID:25523186
NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
G
Casp1
caspase 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of CASP1 mRNA
CTD
PMID:28433809
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
G
Casp3
caspase 3
multiple interactions increases activity increases cleavage increases expression
ISO EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP3 mRNA; [Polyethyleneimine binds to Gold] which results in increased expression of CASP3 mRNA; [Quercetin analog co-treated with Gold analog] results in increased cleavage of CASP3 protein; [Quercetin analog co-treated with Gold analog] results in increased expression of and results in increased activity of CASP3 protein; Dexamethasone promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein] [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP3 protein Gold analog results in increased cleavage of CASP3 protein Gold results in increased expression of CASP3 mRNA
CTD
PMID:19760634 PMID:21621595 PMID:22178767 PMID:25846798 PMID:26551149 PMID:27470402 PMID:27836789 PMID:28433809 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Casp4
caspase 4
increases cleavage
ISO
Gold analog results in increased cleavage of CASP4 protein
CTD
PMID:26551149
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
G
Casp7
caspase 7
increases cleavage
ISO
Gold analog results in increased cleavage of CASP7 protein
CTD
PMID:26551149
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
G
Casp8
caspase 8
increases expression decreases expression
ISO
Gold results in increased expression of CASP8 mRNA Gold analog results in decreased expression of CASP8 mRNA
CTD
PMID:22178767 PMID:36057382
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Casp9
caspase 9
multiple interactions increases cleavage
ISO EXP
[Gold analog co-treated with Platinum] results in increased activity of CASP9 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP9 mRNA Gold analog results in increased cleavage of CASP9 protein [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP9 protein
CTD
PMID:25846798 PMID:26551149 PMID:27836789
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cat
catalase
multiple interactions
ISO
[Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]
CTD
PMID:27836789
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cbx3
chromobox 3
decreases expression
ISO
Gold results in decreased expression of CBX3 mRNA
CTD
PMID:25523186
NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL2 protein Gold results in increased secretion of CCL2 protein
CTD
PMID:22155353
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl5
C-C motif chemokine ligand 5
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL5 protein Gold results in increased secretion of CCL5 protein
CTD
PMID:22155353
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
G
Ccl7
C-C motif chemokine ligand 7
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL7 protein Gold results in increased secretion of CCL7 protein
CTD
PMID:22155353
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
G
Ccnd1
cyclin D1
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased expression of CCND1 protein
CTD
PMID:27470402
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Cct5
chaperonin containing TCP1 subunit 5
decreases expression
ISO
Gold analog results in decreased expression of CCT5 protein
CTD
PMID:24780912
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
G
Cd19
CD19 molecule
increases expression
ISO
Gold analog results in increased expression of CD19 mRNA
CTD
PMID:36057382
NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
G
Cd36
CD36 molecule
decreases expression
ISO
Gold analog results in decreased expression of CD36 mRNA
CTD
PMID:36057382
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cd40
CD40 molecule
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CD40 mRNA
CTD
PMID:28433809
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd86
CD86 molecule
decreases expression
ISO
Gold analog results in decreased expression of CD86 mRNA
CTD
PMID:36057382
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
G
Cda
cytidine deaminase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of CDA mRNA
CTD
PMID:19695318
NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
G
Cdk1
cyclin-dependent kinase 1
decreases expression increases expression
ISO
Gold results in decreased expression of CDK1 mRNA Gold results in increased expression of CDK1 mRNA
CTD
PMID:25523186 PMID:29705079
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdk7
cyclin-dependent kinase 7
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CDK7 mRNA
CTD
PMID:19695318
NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions
ISO
[Gold binds to Dimethyldithiocarbamate] which results in increased expression of CDKN1B protein
CTD
PMID:17079469
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn2aip
CDKN2A interacting protein
decreases expression
ISO
Gold results in decreased expression of CDKN2AIP mRNA
CTD
PMID:25523186
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
G
Cgrrf1
cell growth regulator with ring finger domain 1
decreases expression
ISO
Gold results in decreased expression of CGRRF1 mRNA
CTD
PMID:25523186
NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
G
Chek1
checkpoint kinase 1
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CHEK1 mRNA Gold analog results in decreased expression of CHEK1 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
G
Chek2
checkpoint kinase 2
decreases expression
ISO
Gold analog results in decreased expression of CHEK2 mRNA
CTD
PMID:36057382
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
G
Chordc1
cysteine and histidine rich domain containing 1
decreases expression
ISO
Gold results in decreased expression of CHORDC1 mRNA
CTD
PMID:25523186
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
G
Cisd1
CDGSH iron sulfur domain 1
decreases expression
ISO
Gold results in decreased expression of CISD1 mRNA
CTD
PMID:25523186
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
G
Cldn12
claudin 12
decreases expression
ISO
Gold results in decreased expression of CLDN12 mRNA
CTD
PMID:25523186
NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
G
Cnbp
CCHC-type zinc finger, nucleic acid binding protein
decreases expression
ISO
Gold results in decreased expression of CNBP mRNA
CTD
PMID:25523186
NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
G
Cnot7
CCR4-NOT transcription complex, subunit 7
decreases expression
ISO
Gold results in decreased expression of CNOT7 mRNA
CTD
PMID:25523186
NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
G
Col1a1
collagen type I alpha 1 chain
increases expression
ISO
Gold analog results in increased expression of COL1A1 protein
CTD
PMID:24780912
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
Col1a2
collagen type I alpha 2 chain
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of COL1A2 mRNA
CTD
PMID:19695318
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
G
Col3a1
collagen type III alpha 1 chain
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of COL3A1 mRNA
CTD
PMID:19695318
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
G
Commd8
COMM domain containing 8
decreases expression
ISO
Gold results in decreased expression of COMMD8 mRNA
CTD
PMID:25523186
NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617
G
Cox11
cytochrome c oxidase copper chaperone COX11
decreases expression
ISO
Gold results in decreased expression of COX11 mRNA
CTD
PMID:25523186
NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322
G
Cox17
cytochrome c oxidase copper chaperone COX17
decreases expression
ISO
Gold results in decreased expression of COX17 mRNA
CTD
PMID:25523186
NCBI chr11:62,400,733...62,406,507
G
Cpt1a
carnitine palmitoyltransferase 1A
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CPT1A mRNA
CTD
PMID:28433809
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Cpt2
carnitine palmitoyltransferase 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CPT2 mRNA
CTD
PMID:28433809
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
G
Crot
carnitine O-octanoyltransferase
decreases expression
ISO
Gold analog results in decreased expression of CROT mRNA
CTD
PMID:36057382
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
G
Csf2
colony stimulating factor 2
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CSF2 protein Gold results in increased secretion of CSF2 protein
CTD
PMID:22155353
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
G
Csf3
colony stimulating factor 3
increases secretion multiple interactions
ISO
Gold results in increased secretion of CSF3 protein [Gold co-treated with Silicon Dioxide] results in increased secretion of CSF3 protein
CTD
PMID:22155353
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
G
Ctcf
CCCTC-binding factor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of CTCF mRNA
CTD
PMID:19695318
NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
G
Cux1
cut-like homeobox 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of CUX1 mRNA
CTD
PMID:19695318
NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
G
Cxcl10
C-X-C motif chemokine ligand 10
increases secretion multiple interactions
ISO
Gold results in increased secretion of CXCL10 protein [Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL10 protein
CTD
PMID:22155353
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl2
C-X-C motif chemokine ligand 2
multiple interactions increases secretion
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL2 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL2 protein Gold results in increased secretion of CXCL2 protein
CTD
PMID:19695318 PMID:22155353
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL1 mRNA
CTD
PMID:19695318
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of CYCS protein
CTD
PMID:21621595
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases activity decreases expression multiple interactions
ISO
Gold analog results in increased activity of CYP1A1 protein Gold analog results in decreased expression of CYP1A1 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of CYP1A1 mRNA
CTD
PMID:20193702 PMID:28433809 PMID:36057382
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
increases expression
ISO
Gold results in increased expression of CYP24A1 mRNA
CTD
PMID:29705079
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CYP2D6 mRNA Gold analog results in decreased expression of CYP2D6 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases expression
ISO
Gold analog results in decreased expression of CYP2E1 mRNA
CTD
PMID:36057382
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases expression
ISO
Gold analog results in increased expression of CYP7A1 mRNA
CTD
PMID:36057382
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cyth1
cytohesin 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CYTH1 mRNA
CTD
PMID:19695318
NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
G
Dab2
DAB adaptor protein 2
increases expression
ISO
Gold results in increased expression of DAB2 mRNA
CTD
PMID:29705079
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
G
Dcp2
decapping mRNA 2
decreases expression
ISO
Gold results in decreased expression of DCP2 mRNA
CTD
PMID:25523186
NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
G
Ddc
dopa decarboxylase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of DDC mRNA
CTD
PMID:19695318
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of DDIT3 mRNA
CTD
PMID:28433809
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Ddit4
DNA-damage-inducible transcript 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of DDIT4 mRNA
CTD
PMID:19695318
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
G
Defb1
defensin beta 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DEFB1 mRNA
CTD
PMID:28433809
NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
G
Dhcr24
24-dehydrocholesterol reductase
multiple interactions decreases expression
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of DHCR24 mRNA Gold analog results in decreased expression of DHCR24 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of DHCR24 mRNA
CTD
PMID:19695318 PMID:28433809 PMID:36057382
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
G
Dld
dihydrolipoamide dehydrogenase
decreases expression
ISO
Gold analog results in decreased expression of DLD mRNA
CTD
PMID:36057382
NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
G
Dnah14
dynein axonemal heavy chain 14
decreases expression
ISO
Gold results in decreased expression of DNAH14 mRNA
CTD
PMID:25523186
NCBI chr13:93,322,653...93,540,706
Ensembl chr13:93,322,711...93,538,646
G
Dnaja3
DnaJ heat shock protein family (Hsp40) member A3
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of DNAJA3 mRNA
CTD
PMID:28433809
NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161
G
Dnajb14
DnaJ heat shock protein family (Hsp40) member B14
decreases expression
ISO
Gold results in decreased expression of DNAJB14 mRNA
CTD
PMID:25523186
NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490
G
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
decreases expression
ISO
Gold results in decreased expression of DNAJB6 mRNA
CTD
PMID:25523186
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
G
Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
decreases expression
ISO
Gold results in decreased expression of DNAJB9 mRNA
CTD
PMID:25523186
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
G
Dnajc10
DnaJ heat shock protein family (Hsp40) member C10
decreases expression
ISO
Gold results in decreased expression of DNAJC10 mRNA
CTD
PMID:25523186
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
G
Dnajc19
DnaJ heat shock protein family (Hsp40) member C19
decreases expression
ISO
Gold results in decreased expression of DNAJC19 mRNA
CTD
PMID:25523186
NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
G
Dnajc21
DnaJ heat shock protein family (Hsp40) member C21
decreases expression
ISO
Gold results in decreased expression of DNAJC21 mRNA
CTD
PMID:25523186
NCBI chr 2:59,419,507...59,446,746
Ensembl chr 2:59,419,510...59,446,752
G
Dnajc5
DnaJ heat shock protein family (Hsp40) member C5
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DNAJC5 mRNA
CTD
PMID:28433809
NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
G
Dpysl4
dihydropyrimidinase-like 4
increases expression
ISO
Gold analog results in increased expression of DPYSL4 mRNA
CTD
PMID:36057382
NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
G
Drd3
dopamine receptor D3
multiple interactions
EXP
Gold inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]
CTD
PMID:10215675
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
G
Drd4
dopamine receptor D4
multiple interactions
EXP
Gold inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]
CTD
PMID:10215675
NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
G
Dsc2
desmocollin 2
increases expression
ISO
Gold results in increased expression of DSC2 mRNA
CTD
PMID:29705079
NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
G
Dsg2
desmoglein 2
increases expression
ISO
Gold results in increased expression of DSG2 mRNA
CTD
PMID:29705079
NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
G
Duox1
dual oxidase 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DUOX1 mRNA
CTD
PMID:28433809
NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
G
Duox2
dual oxidase 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DUOX2 mRNA
CTD
PMID:28433809
NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
G
Dusp1
dual specificity phosphatase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of DUSP1 mRNA
CTD
PMID:19695318
NCBI chr10:16,680,478...16,683,275
G
Dusp11
dual specificity phosphatase 11
decreases expression
ISO
Gold results in decreased expression of DUSP11 mRNA
CTD
PMID:25523186
NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
G
Dut
deoxyuridine triphosphatase
decreases expression
ISO
Gold results in decreased expression of DUT mRNA
CTD
PMID:25523186
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
G
Dzip3
DAZ interacting zinc finger protein 3
decreases expression
ISO
Gold results in decreased expression of DZIP3 mRNA
CTD
PMID:25523186
NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
G
Edem3
ER degradation enhancing alpha-mannosidase like protein 3
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of EDEM3 mRNA Gold analog results in decreased expression of EDEM3 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
G
Eea1
early endosome antigen 1
decreases expression
ISO
Gold results in decreased expression of EEA1 mRNA
CTD
PMID:25523186
NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
G
Eef1d
eukaryotic translation elongation factor 1 delta
decreases expression
ISO
Gold analog results in decreased expression of EEF1D protein
CTD
PMID:24780912
NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
G
Eef2
eukaryotic translation elongation factor 2
decreases expression
ISO
Gold analog results in decreased expression of EEF2 protein
CTD
PMID:24780912
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
G
Egf
epidermal growth factor
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]
CTD
PMID:27634460
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
CTD
PMID:27634460
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
decreases expression
ISO
Gold analog results in decreased expression of EHHADH mRNA
CTD
PMID:36057382
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
G
Eid1
EP300 interacting inhibitor of differentiation 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of EID1 mRNA
CTD
PMID:19695318
NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
G
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
decreases expression
ISO
Gold results in decreased expression of EIF1AX mRNA
CTD
PMID:25523186
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
G
Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases phosphorylation
ISO
Gold analog results in increased phosphorylation of EIF2AK3 protein
CTD
PMID:26551149
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
G
Eif4a2
eukaryotic translation initiation factor 4A2
decreases expression
ISO
Gold results in decreased expression of EIF4A2 mRNA
CTD
PMID:25523186
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
G
Eif4e
eukaryotic translation initiation factor 4E
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein
CTD
PMID:27470402
NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
G
Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein
CTD
PMID:27470402
NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024
G
Eif5b
eukaryotic translation initiation factor 5B
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of EIF5B mRNA Gold analog results in decreased expression of EIF5B mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
G
Eno1
enolase 1
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of ENO1 protein
CTD
PMID:24780912
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Ep300
E1A binding protein p300
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Polyethyleneimine binds to Gold] which results in decreased expression of EP300 mRNA; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]
CTD
PMID:27634460 PMID:28433809
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
G
Epgn
epithelial mitogen
increases expression
ISO
Gold results in increased expression of EPGN mRNA
CTD
PMID:29705079
NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806
G
Epha1
Eph receptor A1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of EPHA1 mRNA
CTD
PMID:19695318
NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
G
Ephx1
epoxide hydrolase 1
increases expression
ISO
Gold analog results in increased expression of EPHX1 mRNA
CTD
PMID:36057382
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Ercc2
ERCC excision repair 2, TFIIH core complex helicase subunit
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ERCC2 mRNA
CTD
PMID:28433809
NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
G
Ercc6
ERCC excision repair 6, chromatin remodeling factor
decreases expression
ISO
Gold analog results in decreased expression of ERCC6 mRNA
CTD
PMID:36057382
NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
G
Ern1
endoplasmic reticulum to nucleus signaling 1
increases phosphorylation
ISO
Gold analog results in increased phosphorylation of ERN1 protein
CTD
PMID:26551149
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
G
Ern2
endoplasmic reticulum to nucleus signaling 2
increases expression
ISO
Gold analog results in increased expression of ERN2 mRNA
CTD
PMID:36057382
NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
G
Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
increases expression
ISO
Gold results in increased expression of ERO1A mRNA
CTD
PMID:29705079
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
G
Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
decreases expression
ISO
Gold results in decreased expression of ESCO2 mRNA
CTD
PMID:25523186
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
G
Esr1
estrogen receptor 1
decreases expression
ISO
Gold analog results in decreased expression of ESR1 mRNA
CTD
PMID:36057382
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Evi5
ecotropic viral integration site 5
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of EVI5 mRNA
CTD
PMID:19695318
NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
G
Evx1
even-skipped homeobox 1
increases expression
ISO
Gold results in increased expression of EVX1 mRNA
CTD
PMID:25523186
NCBI chr 4:81,416,590...81,420,967
Ensembl chr 4:81,416,590...81,420,967
G
Fancl
FA complementation group L
decreases expression
ISO
Gold results in decreased expression of FANCL mRNA
CTD
PMID:25523186
NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255
G
Fas
Fas cell surface death receptor
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of FAS mRNA Gold analog results in decreased expression of FAS mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fasn
fatty acid synthase
decreases expression
ISO
Gold analog results in decreased expression of FASN mRNA
CTD
PMID:36057382
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fgf1
fibroblast growth factor 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of FGF1 mRNA
CTD
PMID:19695318
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fh
fumarate hydratase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of FH mRNA
CTD
PMID:28433809
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
G
Fkbp9
FKBP prolyl isomerase 9
increases phosphorylation decreases expression
ISO
Gold analog results in increased phosphorylation of FKBP9 protein Gold analog results in decreased expression of FKBP9 protein
CTD
PMID:24780912
NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
G
Fmo5
flavin containing dimethylaniline monoxygenase 5
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of FMO5 mRNA
CTD
PMID:28433809
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression
ISO
[Gold co-treated with Silicon Dioxide] results in increased expression of FOS mRNA Gold results in increased expression of FOS mRNA
CTD
PMID:22155353
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fth1
ferritin heavy chain 1
increases expression
ISO
Gold results in increased expression of FTH1 mRNA
CTD
PMID:29705079
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Fyb1
FYN binding protein 1
increases expression
ISO
Gold results in increased expression of FYB1 mRNA
CTD
PMID:29705079
NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
G
Fzd4
frizzled class receptor 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of FZD4 mRNA
CTD
PMID:19695318
NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724
G
G2e3
G2/M-phase specific E3 ubiquitin protein ligase
decreases expression
ISO
Gold results in decreased expression of G2E3 mRNA
CTD
PMID:25523186
NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
G
Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
decreases expression
ISO
Gold results in decreased expression of GALNT1 mRNA
CTD
PMID:25523186
NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
G
Galnt5
polypeptide N-acetylgalactosaminyltransferase 5
decreases expression
ISO
Gold analog results in decreased expression of GALNT5 mRNA
CTD
PMID:36057382
NCBI chr 3:42,573,622...42,619,881
Ensembl chr 3:42,573,622...42,619,881
G
Ganc
glucosidase, alpha; neutral C
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of GANC mRNA
CTD
PMID:19695318
NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
decreases expression
ISO
Gold analog results in decreased expression of GAPDH protein
CTD
PMID:24780912
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gca
grancalcin
decreases expression
ISO
Gold results in decreased expression of GCA mRNA
CTD
PMID:25523186
NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
G
Gcdh
glutaryl-CoA dehydrogenase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of GCDH mRNA
CTD
PMID:28433809
NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
G
Gmps
guanine monophosphate synthase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of GMPS mRNA
CTD
PMID:19695318
NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
G
Gng10
G protein subunit gamma 10
decreases expression
ISO
Gold results in decreased expression of GNG10 mRNA
CTD
PMID:25523186
NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012 Ensembl chr 5:73,856,164...73,863,012
G
Got2
glutamic-oxaloacetic transaminase 2
decreases expression
ISO
Gold analog results in decreased expression of GOT2 protein
CTD
PMID:24780912
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
G
Gpr182
G protein-coupled receptor 182
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of GPR182 mRNA
CTD
PMID:19695318
NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210
G
Gpt
glutamic--pyruvic transaminase
multiple interactions decreases expression
ISO
[Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]; [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein] Gold analog results in decreased expression of GPT mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of GPT mRNA
CTD
PMID:27836789 PMID:28433809 PMID:36057382
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx2
glutathione peroxidase 2
increases expression
ISO
Gold analog results in increased expression of GPX2 mRNA; Gold results in increased expression of GPX2 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Gold analog results in increased expression of GPX3 mRNA
CTD
PMID:36057382
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Gsn
gelsolin
decreases expression increases degradation
ISO
Gold analog results in decreased expression of GSN protein Gold analog results in increased degradation of GSN protein
CTD
PMID:24780912 PMID:26551149
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gstm4
glutathione S-transferase mu 4
multiple interactions increases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of GSTM4 mRNA Gold analog results in increased expression of GSTM4 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
G
Haao
3-hydroxyanthranilate 3,4-dioxygenase
increases expression
ISO
Gold analog results in increased expression of HAAO mRNA
CTD
PMID:36057382
NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
G
Hat1
histone acetyltransferase 1
decreases expression
ISO
Gold results in decreased expression of HAT1 mRNA
CTD
PMID:25523186
NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
G
Havcr1
hepatitis A virus cellular receptor 1
multiple interactions
ISO
[Polyethylene Glycols binds to Gold] which results in increased expression of HAVCR1 protein; [Polyethyleneimine binds to Gold] which results in increased expression of HAVCR1 protein; [Thioctic Acid binds to Gold] which results in increased expression of HAVCR1 protein
CTD
PMID:28433809
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
G
Hcar2
hydroxycarboxylic acid receptor 2
increases expression
ISO
Gold results in increased expression of HCAR2 mRNA
CTD
PMID:29705079
NCBI chr12:32,726,252...32,728,238
Ensembl chr12:32,726,184...32,728,504
G
Hexb
hexosaminidase subunit beta
multiple interactions
EXP
[gold chloride results in increased abundance of Gold] which results in increased export of HEXB protein; [gold tetrachloride, acid results in increased abundance of Gold] which results in increased export of HEXB protein
CTD
PMID:21376117
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
G
Hmgb2
high mobility group box 2
decreases expression
ISO
Gold results in decreased expression of HMGB2 mRNA
CTD
PMID:25523186
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
G
Hmox1
heme oxygenase 1
increases expression
ISO
Gold results in increased expression of HMOX1 mRNA
CTD
PMID:25523186
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hoxa3
homeobox A3
decreases expression
ISO
Gold analog results in decreased expression of HOXA3 mRNA
CTD
PMID:36057382
NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
decreases expression
ISO
Gold results in decreased expression of HPRT1 mRNA
CTD
PMID:25523186
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hpx
hemopexin
decreases expression
ISO
Gold analog results in decreased expression of HPX mRNA
CTD
PMID:36057382
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
G
Hsbp1
heat shock factor binding protein 1
decreases expression
ISO
Gold results in decreased expression of HSBP1 mRNA
CTD
PMID:25523186
NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821
G
Hsf1
heat shock transcription factor 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of HSF1 mRNA
CTD
PMID:28433809
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
G
Hsp90ab1
heat shock protein 90 alpha family class B member 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSP90AB1 mRNA
CTD
PMID:19695318
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
G
Hspa13
heat shock protein family A (Hsp70) member 13
decreases expression
ISO
Gold results in decreased expression of HSPA13 mRNA
CTD
PMID:25523186
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1A mRNA
CTD
PMID:28433809
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1B mRNA
CTD
PMID:28433809
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
G
Hspa2
heat shock protein family A (Hsp70) member 2
decreases expression
ISO
Gold analog results in decreased expression of HSPA2 mRNA
CTD
PMID:36057382
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
G
Hspa4
heat shock protein family A (Hsp70) member 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPA4 mRNA
CTD
PMID:19695318
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
G
Hspa8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
Gold analog results in increased expression of HSPA8 protein
CTD
PMID:24780912
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hspa9
heat shock protein family A (Hsp70) member 9
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of HSPA9 mRNA
CTD
PMID:19695318
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPB1 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of HSPB1 mRNA
CTD
PMID:19695318 PMID:28433809
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Hspd1
heat shock protein family D (Hsp60) member 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of HSPD1 mRNA
CTD
PMID:28433809
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
G
Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
Gold results in increased expression of HTATIP2 mRNA
CTD
PMID:29705079
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
G
Htatsf1
HIV-1 Tat specific factor 1
decreases expression
ISO
Gold results in decreased expression of HTATSF1 mRNA
CTD
PMID:25523186
NCBI chr X:134,935,426...134,949,607
Ensembl chr X:134,935,426...134,949,607
G
Htra4
HtrA serine peptidase 4
decreases expression
ISO
Gold analog results in decreased expression of HTRA4 mRNA
CTD
PMID:36057382
NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
G
Hyou1
hypoxia up-regulated 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of HYOU1 mRNA
CTD
PMID:19695318
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
G
Idh1
isocitrate dehydrogenase (NADP(+)) 1
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of IDH1 protein
CTD
PMID:24780912
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
G
Idh3g
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of IDH3G mRNA
CTD
PMID:28433809
NCBI chr X:151,515,244...151,524,175
Ensembl chr X:151,515,247...151,524,171
G
Ifngr1
interferon gamma receptor 1
increases expression
ISO
Gold results in increased expression of IFNGR1 mRNA
CTD
PMID:29705079
NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
G
Igf1
insulin-like growth factor 1
multiple interactions
ISO
Gold inhibits the reaction [IGF1 protein binds to IGF1R protein]
CTD
PMID:9648927
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igf1r
insulin-like growth factor 1 receptor
multiple interactions
ISO
Gold inhibits the reaction [IGF1 protein binds to IGF1R protein]; Gold inhibits the reaction [IGF2 protein binds to IGF1R protein]
CTD
PMID:9648927
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
G
Igf2
insulin-like growth factor 2
multiple interactions
ISO
Gold inhibits the reaction [IGF2 protein binds to IGF1R protein]
CTD
PMID:9648927
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Ikzf2
IKAROS family zinc finger 2
decreases expression
ISO
Gold results in decreased expression of IKZF2 mRNA
CTD
PMID:25523186
NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867
G
Il10
interleukin 10
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of IL10 protein Gold results in increased secretion of IL10 protein
CTD
PMID:22155353
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il1a
interleukin 1 alpha
multiple interactions decreases expression increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein Gold analog results in decreased expression of IL1A mRNA Gold results in increased secretion of IL1A protein
CTD
PMID:22155353 PMID:36057382
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions decreases expression increases secretion
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of IL1B mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1B protein Gold analog results in decreased expression of IL1B mRNA Gold results in increased secretion of IL1B protein
CTD
PMID:19695318 PMID:22155353 PMID:36057382
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il4
interleukin 4
decreases expression
ISO
Gold analog results in decreased expression of IL4 mRNA
CTD
PMID:36057382
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
multiple interactions increases secretion
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of IL6 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL6 protein [Polyethylene Glycols binds to Gold] which results in increased expression of IL6 protein; [Polyethyleneimine binds to Gold] which results in increased expression of IL6 protein; [Thioctic Acid binds to Gold] which results in increased expression of IL6 protein Gold results in increased secretion of IL6 protein
CTD
PMID:19695318 PMID:22155353 PMID:28433809
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Il6r
interleukin 6 receptor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of IL6RA mRNA
CTD
PMID:19695318
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Impa1
inositol monophosphatase 1
decreases expression
ISO
Gold results in decreased expression of IMPA1 mRNA
CTD
PMID:25523186
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
G
Ipmk
inositol polyphosphate multikinase
decreases expression
ISO
Gold results in decreased expression of IPMK mRNA
CTD
PMID:25523186
NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
G
Iqgap2
IQ motif containing GTPase activating protein 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of IQGAP2 mRNA
CTD
PMID:19695318
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
G
Jag1
jagged canonical Notch ligand 1
decreases expression
ISO
Gold analog results in decreased expression of JAG1 mRNA
CTD
PMID:36057382
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
G
Jak2
Janus kinase 2
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein
CTD
PMID:27470402
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]
CTD
PMID:27634460
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Jup
junction plakoglobin
decreases expression
ISO
Gold analog results in decreased expression of JUP protein
CTD
PMID:24780912
NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
G
Khk
ketohexokinase
increases expression
ISO
Gold analog results in increased expression of KHK mRNA
CTD
PMID:36057382
NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
G
Kin
Kin17 DNA and RNA binding protein
decreases expression
ISO
Gold results in decreased expression of KIN mRNA
CTD
PMID:25523186
NCBI chr17:68,413,483...68,431,392
Ensembl chr17:68,413,486...68,423,845
G
Kitlg
KIT ligand
decreases expression
ISO
Gold results in decreased expression of KITLG mRNA
CTD
PMID:25523186
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
G
Krr1
KRR1, small subunit processome component homolog
decreases expression
ISO
Gold results in decreased expression of KRR1 mRNA
CTD
PMID:25523186
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
G
Kynu
kynureninase
increases expression
ISO
Gold results in increased expression of KYNU mRNA
CTD
PMID:29705079
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
G
Lacc1
laccase domain containing 1
increases expression
ISO
Gold results in increased expression of LACC1 mRNA
CTD
PMID:29705079
NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545
G
Lactb2
lactamase, beta 2
decreases expression
ISO
Gold results in decreased expression of LACTB2 mRNA
CTD
PMID:25523186
NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429
G
Larp1b
La ribonucleoprotein 1B
decreases expression
ISO
Gold results in decreased expression of LARP1B mRNA
CTD
PMID:25523186
NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896
G
Lif
LIF, interleukin 6 family cytokine
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of LIF protein Gold results in increased secretion of LIF protein
CTD
PMID:22155353
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
G
Lig4
DNA ligase 4
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which affects the expression of LIG4 mRNA
CTD
PMID:28433809
NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
G
Lima1
LIM domain and actin binding 1
decreases expression
ISO
Gold results in decreased expression of LIMA1 mRNA
CTD
PMID:25523186
NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
G
Lman1
lectin, mannose-binding, 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of LMAN1 mRNA
CTD
PMID:19695318
NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
G
Lmna
lamin A/C
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of LMNA mRNA
CTD
PMID:28433809
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
G
Lmnb1
lamin B1
increases degradation
ISO
Gold analog results in increased degradation of LMNB1 protein
CTD
PMID:26551149
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
G
Lpgat1
lysophosphatidylglycerol acyltransferase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of LPGAT1 mRNA
CTD
PMID:19695318
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
G
Lratd1
LRAT domain containing 1
increases expression
ISO
Gold results in increased expression of LRATD1 mRNA
CTD
PMID:25523186
NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319
G
Lsm5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
decreases expression
ISO
Gold results in decreased expression of LSM5 mRNA
CTD
PMID:25523186
NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165 Ensembl chr 4:104,652,477...104,654,165
G
Lsm6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
decreases expression
ISO
Gold results in decreased expression of LSM6 mRNA
CTD
PMID:25523186
NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484 Ensembl chr19:42,114,032...42,116,484
G
Lss
lanosterol synthase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of LSS mRNA
CTD
PMID:28433809
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
G
Mad2l1
mitotic arrest deficient 2 like 1
decreases expression
ISO
Gold results in decreased expression of MAD2L1 mRNA
CTD
PMID:25523186
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
G
Map1b
microtubule-associated protein 1B
increases expression
ISO
Gold results in increased expression of MAP1B mRNA
CTD
PMID:29705079
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]
CTD
PMID:27634460
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Mbnl2
muscleblind-like splicing regulator 2
decreases expression
ISO
Gold results in decreased expression of MBNL2 mRNA
CTD
PMID:25523186
NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
G
Mdh1b
malate dehydrogenase 1B
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of MDH1B mRNA Gold analog results in decreased expression of MDH1B mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933
G
Mdm2
MDM2 proto-oncogene
decreases expression
ISO
Gold analog results in decreased expression of MDM2 mRNA
CTD
PMID:36057382
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
G
Mecr
mitochondrial trans-2-enoyl-CoA reductase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of MECR mRNA
CTD
PMID:19695318
NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
G
Mefv
MEFV innate immunity regulator, pyrin
increases expression
ISO
Gold results in increased expression of MEFV mRNA
CTD
PMID:25523186
NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
G
Metap2
methionyl aminopeptidase 2
decreases expression
ISO
Gold analog results in decreased expression of METAP2 mRNA; Gold results in decreased expression of METAP2 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
G
Mki67
marker of proliferation Ki-67
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of MKI67 mRNA Gold analog results in decreased expression of MKI67 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
G
Mmgt1
membrane magnesium transporter 1
decreases expression
ISO
Gold results in decreased expression of MMGT1 mRNA
CTD
PMID:25523186
NCBI chr X:134,408,463...134,420,798
Ensembl chr X:134,408,466...134,420,729
G
Mmp3
matrix metallopeptidase 3
increases expression
ISO
Gold results in increased expression of MMP3 mRNA
CTD
PMID:24022940
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
G
Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]
CTD
PMID:27634460
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Mnat1
MNAT1 component of CDK activating kinase
decreases expression
ISO
Gold results in decreased expression of MNAT1 mRNA
CTD
PMID:25523186
NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
G
Mob1b
MOB kinase activator 1B
decreases expression
ISO
Gold results in decreased expression of MOB1B mRNA
CTD
PMID:25523186
NCBI chr14:19,333,058...19,365,845
Ensembl chr14:19,332,459...19,365,845
G
Mob4
MOB family member 4, phocein
decreases expression
ISO
Gold results in decreased expression of MOB4 mRNA
CTD
PMID:25523186
NCBI chr 9:56,617,374...56,641,336
Ensembl chr 9:56,617,368...56,641,329
G
Morc3
MORC family CW-type zinc finger 3
decreases expression
ISO
Gold results in decreased expression of MORC3 mRNA
CTD
PMID:25523186
NCBI chr11:33,151,906...33,194,650
Ensembl chr11:33,152,025...33,194,646
G
Mrpl3
mitochondrial ribosomal protein L3
decreases expression
ISO
Gold results in decreased expression of MRPL3 mRNA
CTD
PMID:25523186
NCBI chr 8:105,670,184...105,693,544
Ensembl chr 8:105,670,184...105,693,544
G
Mrps6
mitochondrial ribosomal protein S6
decreases expression
ISO
Gold results in decreased expression of MRPS6 mRNA
CTD
PMID:25523186
NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
G
Mt1-ps3
metallothionein 1, pseudogene 3
increases expression
ISO
Gold results in increased expression of MT1E mRNA
CTD
PMID:25523186
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
G
Mt2A
metallothionein 2A
increases expression
ISO
Gold results in increased expression of MT2A mRNA
CTD
PMID:25523186
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mthfr
methylenetetrahydrofolate reductase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of MTHFR mRNA
CTD
PMID:19695318
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
G
Mtmr6
myotubularin related protein 6
decreases expression
ISO
Gold results in decreased expression of MTMR6 mRNA
CTD
PMID:25523186
NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
G
Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of MTOR protein
CTD
PMID:27470402
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Mtss1
MTSS I-BAR domain containing 1
increases expression
ISO
Gold results in increased expression of MTSS1 mRNA
CTD
PMID:29705079
NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
G
Mttp
microsomal triglyceride transfer protein
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of MTTP mRNA
CTD
PMID:28433809
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
G
Mycl
MYCL proto-oncogene, bHLH transcription factor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of MYCL mRNA
CTD
PMID:19695318
NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
G
Mynn
myoneurin
decreases expression
ISO
Gold results in decreased expression of MYNN mRNA
CTD
PMID:25523186
NCBI chr 2:112,779,654...112,797,188
Ensembl chr 2:112,779,657...112,796,397
G
Napepld
N-acyl phosphatidylethanolamine phospholipase D
decreases expression
ISO
Gold results in decreased expression of NAPEPLD mRNA
CTD
PMID:25523186
NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
G
Nceh1
neutral cholesterol ester hydrolase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of NCEH1 mRNA
CTD
PMID:19695318
NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity increases expression
ISO
Gold results in increased activity of NFE2L2 promoter Gold analog results in increased expression of NFE2L2 mRNA; Gold analog results in increased expression of NFE2L2 protein
CTD
PMID:21643505 PMID:36057382
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkb1
nuclear factor kappa B subunit 1
decreases expression
ISO
Gold analog results in decreased expression of NFKB1 mRNA
CTD
PMID:36057382
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Nfkbid
NFKB inhibitor delta
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of NFKBID mRNA
CTD
PMID:19695318
NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
G
Nfkbiz
NFKB inhibitor zeta
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of NFKBIZ mRNA
CTD
PMID:19695318
NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
G
Nipbl
NIPBL, cohesin loading factor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of NIPBL mRNA
CTD
PMID:19695318
NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
G
Nos2
nitric oxide synthase 2
increases expression
ISO
Gold results in increased expression of NOS2 protein
CTD
PMID:24022940
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nploc4
NPL4 homolog, ubiquitin recognition factor
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of NPLOC4 mRNA
CTD
PMID:28433809
NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
G
Npm1
nucleophosmin 1
decreases expression
ISO
Gold results in decreased expression of NPM1 mRNA
CTD
PMID:25523186
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
G
Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases expression
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of NQO1 mRNA Gold analog results in increased expression of NQO1 mRNA; Gold results in increased expression of NQO1 mRNA
CTD
PMID:28433809 PMID:29705079 PMID:36057382
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr0b2
nuclear receptor subfamily 0, group B, member 2
decreases expression
ISO
Gold analog results in decreased expression of NR0B2 mRNA
CTD
PMID:36057382
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
G
Nr4a1
nuclear receptor subfamily 4, group A, member 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of NR4A1 mRNA
CTD
PMID:19695318
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
G
Nrcam
neuronal cell adhesion molecule
increases expression
ISO
Gold results in increased expression of NRCAM mRNA
CTD
PMID:29705079
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
G
Nrip1
nuclear receptor interacting protein 1
increases expression
ISO
Gold results in increased expression of NRIP1 mRNA
CTD
PMID:29705079
NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
G
Ntn4
netrin 4
increases expression
ISO
Gold results in increased expression of NTN4 mRNA
CTD
PMID:29705079
NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
G
Nucb1
nucleobindin 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of NUCB1 mRNA
CTD
PMID:28433809
NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
G
Nudt1
nudix hydrolase 1
decreases expression
ISO
Gold analog results in decreased expression of NUDT1 mRNA
CTD
PMID:36057382
NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
G
Nudt12
nudix hydrolase 12
decreases expression
ISO
Gold results in decreased expression of NUDT12 mRNA
CTD
PMID:25523186
NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039
G
Nudt13
nudix hydrolase 13
decreases expression
ISO
Gold analog results in decreased expression of NUDT13 mRNA
CTD
PMID:36057382
NCBI chr15:4,001,787...4,022,404
Ensembl chr15:4,001,794...4,022,293
G
Nup210
nucleoporin 210
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of NUP210 mRNA
CTD
PMID:28433809
NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874
G
Obi1
ORC ubiquitin ligase 1
decreases expression
ISO
Gold results in decreased expression of OBI1 mRNA
CTD
PMID:25523186
NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
G
Odr4
odr-4 GPCR localization factor homolog
decreases expression
ISO
Gold results in decreased expression of ODR4 mRNA
CTD
PMID:25523186
NCBI chr13:62,369,109...62,424,287
Ensembl chr13:62,394,608...62,424,209
G
Ogdh
oxoglutarate dehydrogenase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of OGDH mRNA
CTD
PMID:28433809
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
G
Ogg1
8-oxoguanine DNA glycosylase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of OGG1 mRNA
CTD
PMID:28433809
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
G
Orc4
origin recognition complex, subunit 4
decreases expression
ISO
Gold results in decreased expression of ORC4 mRNA
CTD
PMID:25523186
NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824
G
Os9
OS9, endoplasmic reticulum lectin
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of OS9 mRNA
CTD
PMID:28433809
NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745
G
Osgin1
oxidative stress induced growth inhibitor 1
increases expression
ISO
Gold results in increased expression of OSGIN1 mRNA
CTD
PMID:25523186
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
G
P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
Gold analog results in decreased expression of P4HB protein
CTD
PMID:24780912
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions decreases expression
ISO
Organogold Compounds promotes the reaction [Gold binds to PARP1 protein] Gold analog results in decreased expression of PARP1 mRNA
CTD
PMID:21370912 PMID:36057382
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Pcbp1
poly(rC) binding protein 1
decreases expression
ISO
Gold analog results in decreased expression of PCBP1 protein
CTD
PMID:24780912
NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500
G
Pcca
propionyl-CoA carboxylase subunit alpha
decreases expression
ISO
Gold analog results in decreased expression of PCCA mRNA
CTD
PMID:36057382
NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
G
Pcgf5
polycomb group ring finger 5
decreases expression
ISO
Gold results in decreased expression of PCGF5 mRNA
CTD
PMID:25523186
NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
G
Pcgf6
polycomb group ring finger 6
decreases expression
ISO
Gold results in decreased expression of PCGF6 mRNA
CTD
PMID:25523186
NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
G
Pcna
proliferating cell nuclear antigen
decreases expression
ISO
Gold analog results in decreased expression of PCNA mRNA
CTD
PMID:36057382
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
G
Pde4b
phosphodiesterase 4B
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PDE4B mRNA
CTD
PMID:19695318
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
G
Per3
period circadian regulator 3
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of PER3 mRNA
CTD
PMID:19695318
NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
G
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
decreases expression
ISO
Gold results in decreased expression of PIGA mRNA
CTD
PMID:25523186
NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
G
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
decreases expression
ISO
Gold results in decreased expression of PIGF mRNA
CTD
PMID:25523186
NCBI chr 6:7,589,584...7,617,719
Ensembl chr 6:7,589,570...7,639,675
G
Pigk
phosphatidylinositol glycan anchor biosynthesis, class K
decreases expression
ISO
Gold results in decreased expression of PIGK mRNA
CTD
PMID:25523186
NCBI chr 2:241,630,021...241,715,493
Ensembl chr 2:241,630,053...241,716,134
G
Pigy
phosphatidylinositol glycan anchor biosynthesis, class Y
decreases expression
ISO
Gold results in decreased expression of PIGY mRNA
CTD
PMID:25523186
NCBI chr 8:20,689,621...20,691,863
Ensembl chr 8:20,689,502...20,692,585
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PIK3R1 mRNA
CTD
PMID:19695318
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
G
Pkm
pyruvate kinase M1/2
decreases expression
ISO
Gold analog results in decreased expression of PKM protein
CTD
PMID:24780912
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
G
Pla2g6
phospholipase A2 group VI
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PLA2G6 mRNA
CTD
PMID:19695318
NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
G
Plekhf2
pleckstrin homology and FYVE domain containing 2
decreases expression
ISO
Gold results in decreased expression of PLEKHF2 mRNA
CTD
PMID:25523186
NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
G
Plin3
perilipin 3
increases expression
ISO
Gold analog results in increased expression of PLIN3 protein
CTD
PMID:24780912
NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PMAIP1 mRNA
CTD
PMID:19695318
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
G
Polk
DNA polymerase kappa
decreases expression
ISO
Gold results in decreased expression of POLK mRNA
CTD
PMID:25523186
NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
G
Polr2k
RNA polymerase II, I and III subunit K
decreases expression
ISO
Gold results in decreased expression of POLR2K mRNA
CTD
PMID:25523186
NCBI chr 7:67,347,118...67,359,466
Ensembl chr 7:67,356,113...67,357,668
G
Popdc3
popeye domain containing 3
increases expression
ISO
Gold results in increased expression of POPDC3 mRNA
CTD
PMID:29705079
NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593
G
Por
cytochrome p450 oxidoreductase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of POR mRNA
CTD
PMID:28433809
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ppp1cb
protein phosphatase 1 catalytic subunit beta
decreases expression
ISO
Gold results in decreased expression of PPP1CB mRNA
CTD
PMID:25523186
NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
G
Ppp2r1a
protein phosphatase 2 scaffold subunit A alpha
decreases expression
ISO
Gold analog results in decreased expression of PPP2R1A protein
CTD
PMID:24780912
NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
G
Ppp2r5e
protein phosphatase 2 regulatory subunit B', epsilon
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of PPP2R5E mRNA
CTD
PMID:19695318
NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
G
Prdx1
peroxiredoxin 1
decreases expression increases expression
ISO
Gold analog results in decreased expression of PRDX1 protein Gold analog results in increased expression of PRDX1 mRNA
CTD
PMID:24780912 PMID:36057382
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
G
Prrc2a
proline-rich coiled-coil 2A
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PRRC2A mRNA
CTD
PMID:19695318
NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130
G
Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
Gold analog results in decreased expression of PSAT1 protein
CTD
PMID:24780912
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
G
Psmd14
proteasome 26S subunit, non-ATPase 14
decreases expression
ISO
Gold results in decreased expression of PSMD14 mRNA
CTD
PMID:25523186
NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
G
Ptbp2
polypyrimidine tract binding protein 2
decreases expression
ISO
Gold results in decreased expression of PTBP2 mRNA
CTD
PMID:25523186
NCBI chr 2:207,812,659...207,874,019
Ensembl chr 2:207,812,920...207,873,506
G
Ptgr1
prostaglandin reductase 1
increases expression
ISO
Gold results in increased expression of PTGR1 mRNA
CTD
PMID:29705079
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
G
Ptgr2
prostaglandin reductase 2
decreases expression
ISO
Gold results in decreased expression of PTGR2 mRNA
CTD
PMID:25523186
NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions increases expression
ISO
[Gold co-treated with Silicon Dioxide] results in increased expression of PTGS2 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of PTGS2 mRNA Gold results in increased expression of PTGS2 mRNA
CTD
PMID:22155353 PMID:28433809
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptprc
protein tyrosine phosphatase, receptor type, C
increases expression
ISO
Gold analog results in increased expression of PTPRC mRNA
CTD
PMID:36057382
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
G
Pts
6-pyruvoyl-tetrahydropterin synthase
decreases expression
ISO
Gold results in decreased expression of PTS mRNA
CTD
PMID:25523186
NCBI chr 8:50,870,838...50,877,869
Ensembl chr 8:50,870,841...50,877,869
G
Pvr
PVR cell adhesion molecule
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of PVR mRNA
CTD
PMID:28433809
NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
G
Rab11a
RAB11a, member RAS oncogene family
decreases expression
ISO
Gold results in decreased expression of RAB11A mRNA
CTD
PMID:25523186
NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
G
Rab18
RAB18, member RAS oncogene family
decreases expression
ISO
Gold results in decreased expression of RAB18 mRNA
CTD
PMID:25523186
NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
G
Rabggtb
Rab geranylgeranyltransferase subunit beta
decreases expression
ISO
Gold results in decreased expression of RABGGTB mRNA
CTD
PMID:25523186
NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
G
Rad51
RAD51 recombinase
decreases expression
ISO
Gold analog results in decreased expression of RAD51 mRNA
CTD
PMID:36057382
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
G
Rad51b
RAD51 paralog B
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of RAD51B mRNA
CTD
PMID:19695318
NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
G
Rai14
retinoic acid induced 14
increases expression
ISO
Gold results in increased expression of RAI14 mRNA
CTD
PMID:29705079
NCBI chr 2:59,546,284...59,682,687
Ensembl chr 2:59,546,284...59,681,971
G
Rb1cc1
RB1-inducible coiled-coil 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of RB1CC1 mRNA
CTD
PMID:19695318
NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
G
Rbm12
RNA binding motif protein 12
decreases expression
ISO
Gold results in decreased expression of RBM12 mRNA
CTD
PMID:25523186
NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915 Ensembl chr 3:144,611,623...144,629,915
G
Rbp1
retinol binding protein 1
increases expression
ISO
Gold results in increased expression of RBP1 mRNA
CTD
PMID:29705079
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
G
Rc3h1
ring finger and CCCH-type domains 1
decreases expression
ISO
Gold results in decreased expression of RC3H1 mRNA
CTD
PMID:25523186
NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
G
Rdx
radixin
decreases expression
ISO
Gold analog results in decreased expression of RDX mRNA
CTD
PMID:36057382
NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]
CTD
PMID:27634460
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rfk
riboflavin kinase
decreases expression
ISO
Gold results in decreased expression of RFK mRNA
CTD
PMID:25523186
NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438 Ensembl chr X:214,799,825...214,807,438
G
Rhou
ras homolog family member U
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of RHOU mRNA
CTD
PMID:19695318
NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
G
Rnf11
ring finger protein 11
decreases expression
ISO
Gold results in decreased expression of RNF11 mRNA
CTD
PMID:25523186
NCBI chr 5:124,212,433...124,243,125
Ensembl chr 5:124,212,445...124,234,750
G
Rnf13
ring finger protein 13
decreases expression
ISO
Gold results in decreased expression of RNF13 mRNA
CTD
PMID:25523186
NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801
G
Rnf138
ring finger protein 138
decreases expression
ISO
Gold results in decreased expression of RNF138 mRNA
CTD
PMID:25523186
NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
G
Rnf149
ring finger protein 149
decreases expression
ISO
Gold results in decreased expression of RNF149 mRNA
CTD
PMID:25523186
NCBI chr 9:41,826,825...41,854,381
Ensembl chr 9:41,830,233...41,854,279
G
Rnf2
ring finger protein 2
decreases expression
ISO
Gold results in decreased expression of RNF2 mRNA
CTD
PMID:25523186
NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
G
Rnft1
ring finger protein, transmembrane 1
decreases expression
ISO
Gold results in decreased expression of RNFT1 mRNA
CTD
PMID:25523186
NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778
G
Ro60
Ro60, Y RNA binding protein
decreases expression
ISO
Gold results in decreased expression of RO60 mRNA
CTD
PMID:25523186
NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
G
Rp2
RP2 activator of ARL3 GTPase
decreases expression
ISO
Gold results in decreased expression of RP2 mRNA
CTD
PMID:25523186
NCBI chr X:1,872,582...1,916,704
Ensembl chr X:1,873,306...1,916,688
G
Rps27l
ribosomal protein S27-like
decreases expression
ISO
Gold results in decreased expression of RPS27L mRNA
CTD
PMID:25523186
NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
G
Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein
CTD
PMID:27470402
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
G
RT1-Db1
RT1 class II, locus Db1
increases expression
ISO
Gold analog results in increased expression of HLA-DRB1 mRNA
CTD
PMID:36057382
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
G
Rtn4
reticulon 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of RTN4 mRNA
CTD
PMID:19695318
NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
G
Sar1b
secretion associated, Ras related GTPase 1B
decreases expression
ISO
Gold results in decreased expression of SAR1B mRNA
CTD
PMID:25523186
NCBI chr10:36,024,415...36,054,069
Ensembl chr10:36,024,382...36,054,066
G
Sarnp
SAP domain containing ribonucleoprotein
decreases expression
ISO
Gold results in decreased expression of SARNP mRNA
CTD
PMID:25523186
NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332
G
Scoc
short coiled-coil protein
decreases expression
ISO
Gold results in decreased expression of SCOC mRNA
CTD
PMID:25523186
NCBI chr19:24,659,651...24,689,237
Ensembl chr19:24,659,651...24,693,217
G
Scp2
sterol carrier protein 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of SCP2 mRNA
CTD
PMID:19695318
NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
G
Sec23a
Sec23 homolog A, COPII coat complex component
decreases expression
ISO
Gold results in decreased expression of SEC23A mRNA
CTD
PMID:25523186
NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035
G
Sec24a
SEC24 homolog A, COPII coat complex component
decreases expression
ISO
Gold results in decreased expression of SEC24A mRNA
CTD
PMID:25523186
NCBI chr10:35,946,901...36,024,353
Ensembl chr10:35,947,031...36,024,353
G
Sel1l3
SEL1L family member 3
increases expression
ISO
Gold results in increased expression of SEL1L3 mRNA
CTD
PMID:29705079
NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
G
Selenot
selenoprotein T
decreases expression
ISO
Gold results in decreased expression of SELENOT mRNA
CTD
PMID:25523186
NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427
G
Septin8
septin 8
decreases expression
ISO
Gold analog results in decreased expression of SEPTIN8 protein
CTD
PMID:24780912
NCBI chr10:37,684,649...37,713,704
Ensembl chr10:37,684,639...37,713,174
G
Serp1
stress-associated endoplasmic reticulum protein 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of SERP1 mRNA
CTD
PMID:28433809
NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116
G
Serpine1
serpin family E member 1
increases expression
ISO
Gold results in increased expression of SERPINE1 mRNA
CTD
PMID:29705079
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Serpinh1
serpin family H member 1
decreases expression
ISO
Gold analog results in decreased expression of SERPINH1 protein
CTD
PMID:24780912
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
G
Sh3kbp1
SH3 domain-containing kinase-binding protein 1
increases expression
ISO
Gold results in increased expression of SH3KBP1 mRNA
CTD
PMID:29705079
NCBI chr X:34,877,862...35,223,013
Ensembl chr X:34,877,866...35,222,747
G
Slc25a24
solute carrier family 25 member 24
decreases expression
ISO
Gold analog results in decreased expression of SLC25A24 protein
CTD
PMID:24780912
NCBI chr 2:196,761,076...196,799,236
Ensembl chr 2:196,761,274...196,799,231
G
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`
decreases expression
ISO
Gold results in decreased expression of SMARCAD1 mRNA
CTD
PMID:25523186
NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563
G
Smc4
structural maintenance of chromosomes 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC4 mRNA
CTD
PMID:19695318
NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
G
Smc6
structural maintenance of chromosomes 6
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC6 mRNA
CTD
PMID:19695318
NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746
G
Snrpb2
small nuclear ribonucleoprotein polypeptide B2
decreases expression
ISO
Gold results in decreased expression of SNRPB2 mRNA
CTD
PMID:25523186
NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
G
Snx6
sorting nexin 6
decreases expression
ISO
Gold results in decreased expression of SNX6 mRNA
CTD
PMID:25523186
NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
G
Sod1
superoxide dismutase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of SOD1 mRNA
CTD
PMID:19695318
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sp100
SP100 nuclear antigen
decreases expression
ISO
Gold results in decreased expression of SP100 mRNA
CTD
PMID:25523186
NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
G
Sp3
Sp3 transcription factor
decreases expression
ISO
Gold results in decreased expression of SP3 mRNA
CTD
PMID:25523186
NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
G
Spast
spastin
decreases expression
ISO
Gold results in decreased expression of SPAST mRNA
CTD
PMID:25523186
NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
G
Spata2
spermatogenesis associated 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of SPATA2 mRNA
CTD
PMID:28433809
NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705
G
Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA Gold analog results in decreased expression of SREBF1 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
G
Srek1ip1
SREK1-interacting protein 1
decreases expression
ISO
Gold results in decreased expression of SREK1IP1 mRNA
CTD
PMID:25523186
NCBI chr 2:35,975,978...35,999,636
Ensembl chr 2:35,975,989...35,999,636
G
Srp9
signal recognition particle 9
decreases expression
ISO
Gold results in decreased expression of SRP9 mRNA
CTD
PMID:25523186
NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720
G
Srsf10
serine and arginine rich splicing factor 10
decreases expression
ISO
Gold results in decreased expression of SRSF10 mRNA
CTD
PMID:25523186
NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
G
Srsf3
serine and arginine rich splicing factor 3
decreases expression
ISO
Gold results in decreased expression of SRSF3 mRNA
CTD
PMID:25523186
NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
G
Srsf7
serine and arginine rich splicing factor 7
decreases expression
ISO
Gold results in decreased expression of SRSF7 mRNA
CTD
PMID:25523186
NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
G
Stat1
signal transducer and activator of transcription 1
multiple interactions increases expression
ISO
[Gold co-treated with Silicon Dioxide] results in increased expression of STAT1 mRNA Gold results in increased expression of STAT1 mRNA
CTD
PMID:22155353
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
G
Stat3
signal transducer and activator of transcription 3
increases expression multiple interactions
ISO
Gold results in increased expression of STAT3 mRNA [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA
CTD
PMID:22155353
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stau2
staufen double-stranded RNA binding protein 2
decreases expression
ISO
Gold results in decreased expression of STAU2 mRNA
CTD
PMID:25523186
NCBI chr 5:2,840,741...3,084,935
Ensembl chr 5:2,840,765...3,084,929
G
Stbd1
starch binding domain 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of STBD1 mRNA
CTD
PMID:28433809
NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
G
Steap1
STEAP family member 1
decreases expression
ISO
Gold results in decreased expression of STEAP1 mRNA
CTD
PMID:25523186
NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
G
Stk26
serine/threonine kinase 26
decreases expression
ISO
Gold results in decreased expression of STK26 mRNA
CTD
PMID:25523186
NCBI chr X:130,325,064...130,375,674
Ensembl chr X:130,310,885...130,374,291
G
Sucla2
succinate-CoA ligase ADP-forming subunit beta
decreases expression
ISO
Gold analog results in decreased expression of SUCLA2 mRNA; Gold results in decreased expression of SUCLA2 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
G
Syt1
synaptotagmin 1
decreases expression
ISO
Gold analog results in decreased expression of SYT1 mRNA
CTD
PMID:36057382
NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
G
Syvn1
synoviolin 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of SYVN1 mRNA
CTD
PMID:28433809
NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
G
Tacstd2
tumor-associated calcium signal transducer 2
increases expression
ISO
Gold results in increased expression of TACSTD2 mRNA
CTD
PMID:29705079
NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
G
Tada1
transcriptional adaptor 1
decreases expression
ISO
Gold results in decreased expression of TADA1 mRNA
CTD
PMID:25523186
NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504
G
Taf9b
TATA-box binding protein associated factor 9b
decreases expression
ISO
Gold results in decreased expression of TAF9B mRNA
CTD
PMID:25523186
NCBI chr X:71,289,290...71,300,142
Ensembl chr X:71,289,290...71,300,604
G
Tagln
transgelin
decreases expression
ISO
Gold analog results in decreased expression of TAGLN mRNA
CTD
PMID:36057382
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
G
Tbl1xr1
TBL1X/Y related 1
decreases expression
ISO
Gold results in decreased expression of TBL1XR1 mRNA
CTD
PMID:25523186
NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055
G
Tcea1
transcription elongation factor A1
decreases expression
ISO
Gold results in decreased expression of TCEA1 mRNA
CTD
PMID:25523186
NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745 Ensembl chr15:14,631,454...14,668,745
G
Tdo2
tryptophan 2,3-dioxygenase
decreases expression
ISO
Gold results in decreased expression of TDO2 mRNA
CTD
PMID:25523186
NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
G
Tex30
testis expressed 30
decreases expression
ISO
Gold results in decreased expression of TEX30 mRNA
CTD
PMID:25523186
NCBI chr 9:46,243,416...46,252,273
Ensembl chr 9:46,242,748...46,252,249
G
Tfec
transcription factor EC
decreases expression
ISO
Gold results in decreased expression of TFEC mRNA
CTD
PMID:25523186
NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
G
Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
Gold results in increased expression of TFPI2 mRNA
CTD
PMID:29705079
NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TGFB1 mRNA
CTD
PMID:28433809
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
G
Thap1
THAP domain containing 1
decreases expression
ISO
Gold results in decreased expression of THAP1 mRNA
CTD
PMID:25523186
NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942
G
Tia1
TIA1 cytotoxic granule-associated RNA binding protein
decreases expression
ISO
Gold results in decreased expression of TIA1 mRNA
CTD
PMID:25523186
NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586
G
Tkt
transketolase
decreases expression
ISO
Gold analog results in decreased expression of TKT protein
CTD
PMID:24780912
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
G
Tlk1
tousled-like kinase 1
increases expression
ISO
Gold results in increased expression of TLK1 mRNA
CTD
PMID:29705079
NCBI chr 3:55,520,559...55,627,580
Ensembl chr 3:55,503,358...55,691,968
G
Tlr2
toll-like receptor 2
increases expression multiple interactions
ISO
Gold results in increased expression of TLR2 mRNA Gold promotes the reaction [SAA1 protein binds to TLR2 protein]
CTD
PMID:29705079
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
G
Tm4sf1
transmembrane 4 L six family member 1
increases expression
ISO
Gold results in increased expression of TM4SF1 mRNA
CTD
PMID:29705079
NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
G
Tmed10
transmembrane p24 trafficking protein 10
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of TMED10 mRNA
CTD
PMID:19695318
NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
G
Tnf
tumor necrosis factor
increases secretion multiple interactions
ISO
Gold results in increased secretion of TNF protein [Gold co-treated with Silicon Dioxide] results in increased secretion of TNF protein
CTD
PMID:22155353
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfaip3
TNF alpha induced protein 3
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of TNFAIP3 mRNA
CTD
PMID:19695318
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
G
Tnfaip8l1
TNF alpha induced protein 8 like 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TNFAIP8L1 mRNA
CTD
PMID:28433809
NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254
G
Tnfrsf10b
TNF receptor superfamily member 10b
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TNFRSF10A mRNA
CTD
PMID:28433809
NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
G
Tnfrsf1a
TNF receptor superfamily member 1A
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TNFRSF1A mRNA
CTD
PMID:28433809
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
G
Tnfsf10
TNF superfamily member 10
decreases expression
ISO
Gold analog results in decreased expression of TNFSF10 mRNA
CTD
PMID:36057382
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
G
Tp53
tumor protein p53
increases expression
ISO
Gold analog results in increased expression of TRP53 mRNA
CTD
PMID:22486372
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Tpt1
tumor protein, translationally-controlled 1
decreases expression
ISO
Gold analog results in decreased expression of TPT1 protein
CTD
PMID:24780912
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
G
Trim23
tripartite motif-containing 23
decreases expression
ISO
Gold results in decreased expression of TRIM23 mRNA
CTD
PMID:25523186
NCBI chr 2:35,302,405...35,335,746
Ensembl chr 2:35,302,409...35,335,743
G
Trmt13
tRNA methyltransferase 13 homolog
decreases expression
ISO
Gold results in decreased expression of TRMT13 mRNA
CTD
PMID:25523186
NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843
G
Trub1
TruB pseudouridine synthase family member 1
decreases expression
ISO
Gold results in decreased expression of TRUB1 mRNA
CTD
PMID:25523186
NCBI chr 1:256,513,418...256,554,549
Ensembl chr 1:256,515,562...256,552,814
G
Tuba1a
tubulin, alpha 1A
decreases expression
ISO
Gold analog results in decreased expression of TUBA1A protein
CTD
PMID:24780912
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
G
Tubb5
tubulin, beta 5 class I
decreases expression
ISO
Gold analog results in decreased expression of TUBB5 protein
CTD
PMID:24780912
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
G
Tufm
Tu translation elongation factor, mitochondrial
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of TUFM protein
CTD
PMID:24780912
NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
G
Txndc5
thioredoxin domain containing 5
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of TXNDC5 protein
CTD
PMID:24780912
NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
G
Txnip
thioredoxin interacting protein
decreases expression
ISO
Gold analog results in decreased expression of TXNIP mRNA
CTD
PMID:36057382
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
G
Txnrd1
thioredoxin reductase 1
decreases activity increases expression
EXP ISO
Gold results in decreased activity of TXNRD1 protein Gold results in increased expression of TXNRD1 mRNA
CTD
PMID:16510263 PMID:20851179 PMID:29705079
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
G
Txnrd2
thioredoxin reductase 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TXNRD2 mRNA
CTD
PMID:28433809
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
G
Uap1l1
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
decreases expression
ISO
Gold analog results in decreased expression of UAP1L1 protein
CTD
PMID:24780912
NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443
G
Uba2
ubiquitin-like modifier activating enzyme 2
decreases expression
ISO
Gold results in decreased expression of UBA2 mRNA
CTD
PMID:25523186
NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682
G
Ube2g2
ubiquitin-conjugating enzyme E2G 2
decreases expression
ISO
Gold analog results in decreased expression of UBE2G2 mRNA
CTD
PMID:36057382
NCBI chr20:10,983,734...11,005,468
Ensembl chr20:10,983,742...11,005,447
G
Ube2h
ubiquitin-conjugating enzyme E2H
increases expression
ISO
Gold results in increased expression of UBE2H mRNA
CTD
PMID:29705079
NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156
G
Ube2n
ubiquitin-conjugating enzyme E2N
decreases expression
ISO
Gold results in decreased expression of UBE2N mRNA
CTD
PMID:25523186
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
G
Ube2w
ubiquitin-conjugating enzyme E2W
decreases expression
ISO
Gold results in decreased expression of UBE2W mRNA
CTD
PMID:25523186
NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965
G
Ucp2
uncoupling protein 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of UCP2 mRNA
CTD
PMID:28433809
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
decreases expression
ISO
Gold analog results in decreased expression of UGT1A1 mRNA
CTD
PMID:36057382
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt2a1
UDP glucuronosyltransferase family 2 member A1
decreases expression
ISO
Gold analog results in decreased expression of UGT2A1 mRNA
CTD
PMID:36057382
NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531
G
Uimc1
ubiquitin interaction motif containing 1
increases expression decreases expression
ISO
Gold results in increased expression of UIMC1 mRNA Gold results in decreased expression of UIMC1 mRNA
CTD
PMID:29705079
NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799
G
Upp2
uridine phosphorylase 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of UPP2 mRNA
CTD
PMID:19695318
NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
G
Usp1
ubiquitin specific peptidase 1
decreases expression
ISO
Gold results in decreased expression of USP1 mRNA
CTD
PMID:25523186
NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
G
Usp15
ubiquitin specific peptidase 15
decreases expression
ISO
Gold results in decreased expression of USP15 mRNA
CTD
PMID:25523186
NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
G
Usp16
ubiquitin specific peptidase 16
decreases expression
ISO
Gold results in decreased expression of USP16 mRNA
CTD
PMID:25523186
NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539
G
Usp33
ubiquitin specific peptidase 33
decreases expression
ISO
Gold results in decreased expression of USP33 mRNA
CTD
PMID:25523186
NCBI chr 2:241,283,209...241,328,479
Ensembl chr 2:241,292,985...241,328,479
G
Usp5
ubiquitin specific peptidase 5
decreases expression
ISO
Gold analog results in decreased expression of USP5 protein
CTD
PMID:24780912
NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
G
Vcl
vinculin
decreases expression
ISO
Gold analog results in decreased expression of VCL protein
CTD
PMID:24780912
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
G
Vim
vimentin
increases degradation
ISO
Gold analog results in increased degradation of VIM protein
CTD
PMID:26551149
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
G
Wbp4
WW domain binding protein 4
decreases expression
ISO
Gold results in decreased expression of WBP4 mRNA
CTD
PMID:25523186
NCBI chr15:54,862,700...54,890,668
Ensembl chr15:54,862,843...54,890,647
G
Wee1
WEE1 G2 checkpoint kinase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of WEE1 mRNA
CTD
PMID:19695318
NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
G
Xpa
XPA, DNA damage recognition and repair factor
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of XPA mRNA
CTD
PMID:28433809
NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
G
Xpc
XPC complex subunit, DNA damage recognition and repair factor
decreases expression
ISO
Gold analog results in decreased expression of XPC mRNA
CTD
PMID:36057382
NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
G
Xrcc5
X-ray repair cross complementing 5
decreases expression
ISO
Gold analog results in decreased expression of XRCC5 mRNA
CTD
PMID:36057382
NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
G
Yod1
YOD1 deubiquitinase
decreases expression
ISO
Gold results in decreased expression of YOD1 mRNA
CTD
PMID:25523186
NCBI chr13:42,175,047...42,181,661
Ensembl chr13:42,174,820...42,177,205
G
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of YWHAG mRNA
CTD
PMID:19695318
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
G
Zbtb21
zinc finger and BTB domain containing 21
decreases expression
ISO
Gold results in decreased expression of ZBTB21 mRNA
CTD
PMID:25523186
NCBI chr11:37,312,337...37,327,040
Ensembl chr11:37,312,378...37,326,996
G
Zbtb41
zinc finger and BTB domain containing 41
decreases expression
ISO
Gold results in decreased expression of ZBTB41 mRNA
CTD
PMID:25523186
NCBI chr13:51,042,948...51,065,768
Ensembl chr13:51,042,948...51,065,768
G
Zc3h15
zinc finger CCCH-type containing 15
decreases expression
ISO
Gold results in decreased expression of ZC3H15 mRNA
CTD
PMID:25523186
NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333
G
Zcchc10
zinc finger CCHC-type containing 10
decreases expression
ISO
Gold results in decreased expression of ZCCHC10 mRNA
CTD
PMID:25523186
NCBI chr10:37,470,628...37,481,027
G
Zcchc9
zinc finger CCHC-type containing 9
decreases expression
ISO
Gold results in decreased expression of ZCCHC9 mRNA
CTD
PMID:25523186
NCBI chr 2:23,038,156...23,048,249
Ensembl chr 2:23,038,317...23,048,217
G
Zcrb1
zinc finger CCHC-type and RNA binding motif containing 1
decreases expression
ISO
Gold results in decreased expression of ZCRB1 mRNA
CTD
PMID:25523186
NCBI chr 7:124,525,227...124,538,564
Ensembl chr 7:124,524,870...124,571,261
G
Zdhhc17
zinc finger DHHC-type palmitoyltransferase 17
decreases expression
ISO
Gold results in decreased expression of ZDHHC17 mRNA
CTD
PMID:25523186
NCBI chr 7:46,369,963...46,433,691
Ensembl chr 7:46,369,988...46,433,764
G
Zdhhc20
zinc finger DHHC-type palmitoyltransferase 20
decreases expression
ISO
Gold results in decreased expression of ZDHHC20 mRNA
CTD
PMID:25523186
NCBI chr15:31,980,057...32,039,006
Ensembl chr15:31,983,155...32,038,989
G
Zfand1
zinc finger AN1-type containing 1
decreases expression
ISO
Gold results in decreased expression of ZFAND1 mRNA
CTD
PMID:25523186
NCBI chr 2:91,444,497...91,457,540
Ensembl chr 2:91,444,508...91,453,246
G
Zfand6
zinc finger AN1-type containing 6
decreases expression
ISO
Gold results in decreased expression of ZFAND6 mRNA
CTD
PMID:25523186
NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
G
Zfp277
zinc finger protein 277
decreases expression
ISO
Gold results in decreased expression of ZNF277 mRNA
CTD
PMID:25523186
NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:57,383,951...57,512,765
G
Zfp422
zinc finger protein 422
decreases expression
ISO
Gold results in decreased expression of ZNF22 mRNA
CTD
PMID:25523186
NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257
G
Zfyve16
zinc finger FYVE-type containing 16
decreases expression
ISO
Gold results in decreased expression of ZFYVE16 mRNA
CTD
PMID:25523186
NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990
G
Zmpste24
zinc metallopeptidase STE24
decreases expression
ISO
Gold results in decreased expression of ZMPSTE24 mRNA
CTD
PMID:25523186
NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
G
Zranb2
zinc finger RANBP2-type containing 2
decreases expression
ISO
Gold results in decreased expression of ZRANB2 mRNA
CTD
PMID:25523186
NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942
G
Zup1
zinc finger containing ubiquitin peptidase 1
decreases expression
ISO
Gold results in decreased expression of ZUP1 mRNA
CTD
PMID:25523186
NCBI chr20:30,785,226...30,815,377
Ensembl chr20:30,785,227...30,815,306
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased phosphorylation of AKT1 protein]
CTD
PMID:36343453
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alb
albumin
affects binding
ISO
Auranofin analog binds to ALB protein
CTD
PMID:16791640
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Bak1
BCL2-antagonist/killer 1
multiple interactions increases response to substance
ISO
[BAX co-treated with BAK1] results in increased susceptibility to Auranofin; BAK1 mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein] BAK1 results in increased susceptibility to Auranofin
CTD
PMID:18789312 PMID:21172426
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases response to substance
ISO
[BAX co-treated with BAK1] results in increased susceptibility to Auranofin; BAX mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein] BAX results in increased susceptibility to Auranofin
CTD
PMID:18789312 PMID:21172426
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
BCL2 protein inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
CTD
PMID:18789312
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Casp3
caspase 3
multiple interactions increases activity
ISO EXP
Auranofin promotes the reaction [TNF protein results in increased activity of CASP3 protein]; Auranofin results in decreased expression of and results in increased cleavage of CASP3 protein; BCL2 protein inhibits the reaction [Auranofin results in increased activity of CASP3 protein] BAK1 mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]; BAX mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
CTD
PMID:15159275 PMID:15191400 PMID:18789312 PMID:20542334 PMID:21699084
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
multiple interactions
ISO
Auranofin results in decreased expression of and results in increased cleavage of CASP8 protein
CTD
PMID:20542334
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
multiple interactions
ISO
Auranofin results in decreased expression of and results in increased cleavage of CASP9 protein
CTD
PMID:20542334
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Auranofin results in increased expression of CDKN1A protein
CTD
PMID:20542334
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cebpe
CCAAT/enhancer binding protein epsilon
multiple interactions
ISO
[Auranofin co-treated with Tretinoin] results in increased expression of CEBPE protein
CTD
PMID:15159275
NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
multiple interactions
ISO
Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; Auranofin inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein]
CTD
PMID:10820281
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Dio1
iodothyronine deiodinase 1
decreases activity
ISO
Auranofin results in decreased activity of DIO1 protein
CTD
PMID:34662569
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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Egf
epidermal growth factor
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased expression of and results in increased secretion of EGF protein]
CTD
PMID:36343453
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Gpx1
glutathione peroxidase 1
multiple interactions increases expression
ISO
[Peptidoglycan co-treated with Lipopolysaccharides] promotes the reaction [Auranofin results in increased expression of GPX1 protein]; Auranofin promotes the reaction [[Lipopolysaccharides co-treated with Peptidoglycan] results in increased expression of GPX1 protein]
CTD
PMID:21355852
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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Gsr
glutathione-disulfide reductase
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased activity of GSR protein]
CTD
PMID:36343453
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Hmox1
heme oxygenase 1
increases expression
ISO
Auranofin results in increased expression of HMOX1 mRNA Auranofin results in increased expression of HMOX1 mRNA; Auranofin results in increased expression of HMOX1 protein
CTD
PMID:22008538 PMID:23942037
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Il1b
interleukin 1 beta
multiple interactions
ISO
Auranofin inhibits the reaction [IL1B protein affects the localization of RELA protein]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD
PMID:10594346
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions
ISO
[Auranofin co-treated with IL6 protein] results in decreased phosphorylation of IL6ST protein; [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein; [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein
CTD
PMID:20542334
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Il6st
interleukin 6 cytokine family signal transducer
multiple interactions
ISO
[Auranofin co-treated with IL6 protein] results in decreased phosphorylation of IL6ST protein
CTD
PMID:20542334
NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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Irak1
interleukin-1 receptor-associated kinase 1
multiple interactions
ISO
Auranofin inhibits the reaction [lipopolysaccharide A results in increased degradation of IRAK1 protein]
CTD
PMID:17034761
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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Irf3
interferon regulatory factor 3
multiple interactions
ISO
Auranofin inhibits the reaction [lipopolysaccharide A results in increased activity of IRF3 protein]; Auranofin inhibits the reaction [lipopolysaccharide A results in increased phosphorylation of IRF3 protein]; Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein]; Auranofin inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein]
CTD
PMID:17034761
NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
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Itgam
integrin subunit alpha M
multiple interactions
ISO
[Auranofin co-treated with Tretinoin] results in increased expression of ITGAM protein
CTD
PMID:15159275
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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Jak2
Janus kinase 2
multiple interactions
ISO
[Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein
CTD
PMID:20542334
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased phosphorylation of MAPK1 protein]
CTD
PMID:36343453
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased phosphorylation of MAPK3 protein]
CTD
PMID:36343453
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased phosphorylation of MAPK8 protein]
CTD
PMID:36343453
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mcl1
MCL1 apoptosis regulator, BCL2 family member
multiple interactions decreases expression
ISO
[Auranofin co-treated with SN50 peptide] results in decreased expression of MCL1 protein Auranofin results in decreased expression of MCL1 protein
CTD
PMID:20542334
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased expression of NFE2L2 protein]
CTD
PMID:36343453
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
Auranofin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
CTD
PMID:10820281
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nfkbib
NFKB inhibitor beta
multiple interactions
ISO
Auranofin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein]
CTD
PMID:10820281
NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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Parp1
poly (ADP-ribose) polymerase 1
decreases activity increases cleavage
ISO
Auranofin results in decreased activity of PARP1 protein Auranofin results in increased cleavage of PARP1 protein
CTD
PMID:15159275 PMID:21370912
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Ppif
peptidylprolyl isomerase F
increases oxidation multiple interactions
ISO EXP
Auranofin results in increased oxidation of PPIF protein Auranofin inhibits the reaction [[NADP co-treated with TXNRD1 protein] results in increased activity of PPIF protein]; Cyclosporine promotes the reaction [Auranofin results in increased oxidation of PPIF protein]
CTD
PMID:26975474
NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
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Prdx3
peroxiredoxin 3
increases oxidation multiple interactions
ISO EXP
Auranofin results in increased oxidation of PRDX3 protein Cyclosporine promotes the reaction [Auranofin results in increased oxidation of PRDX3 protein] Auranofin promotes the reaction [[Lipopolysaccharides co-treated with Peptidoglycan] results in increased expression of PRDX3 protein]
CTD
PMID:18789312 PMID:21355852 PMID:26975474
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[lipopolysaccharide A co-treated with Auranofin] results in decreased expression of PTGS2 protein Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD
PMID:10594346 PMID:17034761
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Rb1
RB transcriptional corepressor 1
decreases phosphorylation
ISO
Auranofin results in decreased phosphorylation of RB1 protein
CTD
PMID:20542334
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Rbms3
RNA binding motif, single stranded interacting protein 3
affects response to substance
ISO
RBMS3 protein affects the susceptibility to Auranofin
CTD
PMID:36414028
NCBI chr 8:116,305,227...117,625,730
Ensembl chr 8:116,309,882...117,625,423
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
Auranofin inhibits the reaction [IL1B protein affects the localization of RELA protein]; Auranofin promotes the reaction [arsenite results in increased phosphorylation of RELA protein]
CTD
PMID:10594346 PMID:36343453
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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RT1-Ba
RT1 class II, locus Ba
increases response to substance
ISO
HLA-DQA1 gene polymorphism results in increased susceptibility to Auranofin
CTD
PMID:11436868
NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
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RT1-Db1
RT1 class II, locus Db1
increases response to substance
ISO
HLA-DRB1 gene polymorphism results in increased susceptibility to Auranofin
CTD
PMID:11436868
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Auranofin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Stat3
signal transducer and activator of transcription 3
decreases expression multiple interactions
ISO
Auranofin results in decreased expression of STAT3 protein modified form [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein
CTD
PMID:20542334
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Tbk1
TANK-binding kinase 1
multiple interactions
ISO
Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein]
CTD
PMID:17034761
NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
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Tgfa
transforming growth factor alpha
multiple interactions
ISO
Auranofin promotes the reaction [arsenite results in increased expression of and results in increased secretion of TGFA protein]
CTD
PMID:36343453
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Ticam1
TIR domain containing adaptor molecule 1
multiple interactions
ISO
Auranofin inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein]
CTD
PMID:17034761
NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
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Tlr4
toll-like receptor 4
multiple interactions
ISO
Auranofin inhibits the reaction [lipopolysaccharide A promotes the reaction [TLR4 protein binds to TLR4 protein]]
CTD
PMID:17034761
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tnf
tumor necrosis factor
multiple interactions
ISO
Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Auranofin promotes the reaction [TNF protein results in increased activity of CASP3 protein] Auranofin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD
PMID:10820281 PMID:18789312
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Txn1
thioredoxin 1
increases oxidation multiple interactions
ISO
Auranofin results in increased oxidation of TXN protein Auranofin inhibits the reaction [arsenite results in increased expression of TXN protein]
CTD
PMID:26975474 PMID:36343453
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txn2
thioredoxin 2
increases oxidation multiple interactions
ISO EXP
Auranofin results in increased oxidation of TXN2 protein Cyclosporine promotes the reaction [Auranofin results in increased oxidation of TXN2 protein]
CTD
PMID:26975474
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
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Txnrd1
thioredoxin reductase 1
multiple interactions decreases activity increases oxidation increases expression
ISO EXP
Auranofin inhibits the reaction [arsenite results in increased expression of and results in increased activity of TXNRD1 protein]; Auranofin inhibits the reaction [Sodium Selenite results in increased activity of TXNRD1 protein]; Auranofin promotes the reaction [Sodium Selenite results in increased expression of TXNRD1 mRNA]; potassium tellurate(IV) promotes the reaction [Auranofin results in increased oxidation of TXNRD1 protein]; Sodium Selenite promotes the reaction [Auranofin results in increased oxidation of TXNRD1 protein] Auranofin inhibits the reaction [[NADP co-treated with TXNRD1 protein] results in increased activity of PPIF protein]; Auranofin inhibits the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides] Auranofin results in decreased activity of TXNRD1 protein Auranofin results in increased expression of TXNRD1 mRNA
CTD
PMID:16510263 PMID:18405881 PMID:18789312 PMID:19486940 PMID:20457604 PMID:21172426 PMID:26975474 PMID:36343453 More...
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Txnrd2
thioredoxin reductase 2
multiple interactions decreases activity
ISO EXP
Auranofin inhibits the reaction [Sodium Selenite results in increased activity of TXNRD2 protein]; Auranofin promotes the reaction [Sodium Selenite results in decreased expression of TXNRD2 mRNA] Auranofin results in decreased activity of TXNRD2 protein
CTD
PMID:15458826 PMID:19486940 PMID:21172426 PMID:21355852
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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Tnf
tumor necrosis factor
decreases secretion
EXP
Topical GNP decreases secretion of Tnf protein in aqeous humor
RGD
PMID:23150627
RGD:7815044
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Aass
aminoadipate-semialdehyde synthase
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of AASS mRNA Gold analog results in decreased expression of AASS mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
G
Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
ISO
Gold analog results in increased expression of ABCB1 mRNA
CTD
PMID:36057382
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Abcb4
ATP binding cassette subfamily B member 4
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA Gold analog results in decreased expression of ABCB4 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
G
Abcc1
ATP binding cassette subfamily C member 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ABCC1 mRNA
CTD
PMID:28433809
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
ISO
Gold analog results in increased expression of ABCC2 mRNA
CTD
PMID:36057382
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ABL1 mRNA
CTD
PMID:28433809
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
G
Acaa1a
acetyl-CoA acyltransferase 1A
decreases expression
ISO
Gold analog results in decreased expression of ACAA1 mRNA
CTD
PMID:36057382
NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
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Acaca
acetyl-CoA carboxylase alpha
decreases expression
ISO
Gold analog results in decreased expression of ACACA mRNA
CTD
PMID:36057382
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acad11
acyl-CoA dehydrogenase family, member 11
decreases expression
ISO
Gold analog results in decreased expression of ACAD11 mRNA
CTD
PMID:36057382
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acadm
acyl-CoA dehydrogenase medium chain
decreases expression
ISO
Gold analog results in decreased expression of ACADM mRNA
CTD
PMID:36057382
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acads
acyl-CoA dehydrogenase short chain
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ACADS mRNA
CTD
PMID:28433809
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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Acadvl
acyl-CoA dehydrogenase, very long chain
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ACADVL mRNA
CTD
PMID:28433809
NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
G
Aco1
aconitase 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of ACO1 mRNA
CTD
PMID:28433809
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
G
Aco2
aconitase 2
decreases expression multiple interactions
ISO
Gold analog results in decreased expression of ACO2 protein [Polyethyleneimine binds to Gold] which results in increased expression of ACO2 mRNA
CTD
PMID:24780912 PMID:28433809
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
G
Acox1
acyl-CoA oxidase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ACOX1 mRNA
CTD
PMID:19695318
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
G
Acox2
acyl-CoA oxidase 2
decreases expression
ISO
Gold analog results in decreased expression of ACOX2 mRNA
CTD
PMID:36057382
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
G
Acp1
acid phosphatase 1
decreases expression
ISO
Gold results in decreased expression of ACP1 mRNA
CTD
PMID:25523186
NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
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Acvr1c
activin A receptor type 1C
decreases expression
ISO
Gold results in decreased expression of ACVR1C mRNA
CTD
PMID:25523186
NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
G
Adam28
ADAM metallopeptidase domain 28
increases expression
ISO
Gold results in increased expression of ADAM28 mRNA
CTD
PMID:29705079
NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
G
Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
decreases expression
ISO
Gold results in decreased expression of ADH5 mRNA
CTD
PMID:25523186
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
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Adipor2
adiponectin receptor 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ADIPOR2 mRNA
CTD
PMID:19695318
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
G
Adra1b
adrenoceptor alpha 1B
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of ADRA1B mRNA
CTD
PMID:19695318
NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
G
Adrb2
adrenoceptor beta 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of ADRB2 mRNA
CTD
PMID:19695318
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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Ahsg
alpha-2-HS-glycoprotein
decreases expression
ISO
Gold analog results in decreased expression of AHSG mRNA
CTD
PMID:36057382
NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
increases expression
ISO
Gold results in increased expression of AIFM1 protein
CTD
PMID:25462594
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
G
Aimp1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
decreases expression
ISO
Gold results in decreased expression of AIMP1 mRNA
CTD
PMID:25523186
NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
G
Ak3
adenylate kinase 3
decreases expression
ISO
Gold results in decreased expression of AK3 mRNA
CTD
PMID:25523186
NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
G
Akap13
A-kinase anchoring protein 13
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of AKAP13 mRNA
CTD
PMID:19695318
NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
G
Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
Gold results in increased expression of AKR1B10 mRNA
CTD
PMID:29705079
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
G
Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
Gold results in increased expression of AKR1C2 mRNA
CTD
PMID:29705079
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
G
Akr1c3
aldo-keto reductase family 1, member C3
increases expression
ISO
Gold results in increased expression of AKR1C3 mRNA
CTD
PMID:29705079
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of AKT1 protein
CTD
PMID:27470402
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
G
Alb
albumin
multiple interactions increases expression
ISO
ALB protein results in increased uptake of [Polyethylene Glycols binds to Gold]; ALB protein results in increased uptake of [Polyethyleneimine binds to Gold]; ALB protein results in increased uptake of [Thioctic Acid binds to Gold] Gold analog results in increased expression of ALB mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Anxa5
annexin A5
increases expression
ISO
Gold analog results in increased expression of ANXA5 protein
CTD
PMID:24780912
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
G
Apaf1
apoptotic peptidase activating factor 1
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein Gold analog results in decreased expression of APAF1 mRNA
CTD
PMID:27470402 PMID:28433809 PMID:36057382
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
G
Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
decreases expression
ISO
Gold analog results in decreased expression of APEX1 mRNA
CTD
PMID:36057382
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
G
Apoa4
apolipoprotein A4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of APOA4 mRNA
CTD
PMID:19695318
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
G
Aprt
adenine phosphoribosyl transferase
decreases expression
ISO
Gold analog results in decreased expression of APRT protein
CTD
PMID:24780912
NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431
G
Aqp4
aquaporin 4
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of AQP4 mRNA
CTD
PMID:28433809
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
G
Arl1
ADP-ribosylation factor like GTPase 1
decreases expression
ISO
Gold results in decreased expression of ARL1 mRNA
CTD
PMID:25523186
NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
G
Arl5b
ADP-ribosylation factor like GTPase 5B
decreases expression
ISO
Gold results in decreased expression of ARL5B mRNA
CTD
PMID:25523186
NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
G
Arsg
arylsulfatase G
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ARSG mRNA
CTD
PMID:19695318
NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
G
Asah1
N-acylsphingosine amidohydrolase 1
decreases expression
ISO
Gold analog results in decreased expression of ASAH1 mRNA
CTD
PMID:36057382
NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
G
Atf1
activating transcription factor 1
decreases expression
ISO
Gold results in decreased expression of ATF1 mRNA
CTD
PMID:25523186
NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
G
Atf4
activating transcription factor 4
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ATF4 mRNA
CTD
PMID:28433809
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
G
Atf6
activating transcription factor 6
increases cleavage
ISO
Gold analog results in increased cleavage of ATF6 protein
CTD
PMID:26551149
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
G
Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
decreases expression
ISO
Gold analog results in decreased expression of ATIC protein
CTD
PMID:24780912
NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
G
Atl2
atlastin GTPase 2
decreases expression
ISO
Gold results in decreased expression of ATL2 mRNA
CTD
PMID:25523186
NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421
G
Atm
ATM serine/threonine kinase
decreases expression
ISO
Gold analog results in decreased expression of ATM mRNA
CTD
PMID:36057382
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
G
Atp2b1
ATPase plasma membrane Ca2+ transporting 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of ATP2B1 mRNA
CTD
PMID:19695318
NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
G
Atp5f1b
ATP synthase F1 subunit beta
multiple interactions
ISO
Gold analog results in increased expression of and results in decreased phosphorylation of ATP5F1B protein
CTD
PMID:24780912
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
G
Atp6v1g2
ATPase H+ transporting V1 subunit G2
decreases expression
ISO
Gold analog results in decreased expression of ATP6V1G2 mRNA
CTD
PMID:36057382
NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481
G
Atr
ATR serine/threonine kinase
decreases expression
ISO
Gold analog results in decreased expression of ATR mRNA
CTD
PMID:36057382
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
G
Bace1
beta-secretase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of BACE1 mRNA
CTD
PMID:19695318
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
G
Bad
BCL2-associated agonist of cell death
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in increased expression of BAD protein
CTD
PMID:27470402
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
G
Baiap2
BAR/IMD domain containing adaptor protein 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of BAIAP2 mRNA
CTD
PMID:19695318
NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
G
Bak1
BCL2-antagonist/killer 1
increases expression
ISO
Gold results in increased expression of BAK1 mRNA
CTD
PMID:22178767
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of BAX protein; [Gold analog co-treated with Platinum] results in increased expression of BAX mRNA; [Polyethyleneimine binds to Gold] which results in decreased expression of BAX mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of BAX protein [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of BAX protein Gold results in increased expression of BAX mRNA
CTD
PMID:21621595 PMID:22178767 PMID:25846798 PMID:27470402 PMID:27836789 PMID:28433809 More...
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcas2
BCAS2, pre-mRNA processing factor
decreases expression
ISO
Gold results in decreased expression of BCAS2 mRNA
CTD
PMID:25523186
NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO EXP
[Gold analog co-treated with Platinum] results in decreased expression of BCL2 mRNA; [Quercetin analog co-treated with Gold analog] results in decreased expression of BCL2 protein [Gold binds to NKCT1 protein, Naja kaouthia] which results in decreased expression of BCL2 protein
CTD
PMID:25846798 PMID:27470402 PMID:27836789
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bcl2l1
Bcl2-like 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of BCL2L1 mRNA
CTD
PMID:28433809
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
G
Bcl2l11
Bcl2-like 11
decreases expression
ISO
Gold analog results in decreased expression of BCL2L11 mRNA
CTD
PMID:36057382
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
G
Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
Gold results in decreased expression of BIRC2 mRNA
CTD
PMID:25523186
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
G
Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
Gold analog results in decreased expression of BIRC3 mRNA; Gold results in decreased expression of BIRC3 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
G
Bmal1
basic helix-loop-helix ARNT like 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of BMAL1 mRNA
CTD
PMID:19695318
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
G
Bmi1
BMI1 proto-oncogene, polycomb ring finger
decreases expression
ISO
Gold results in decreased expression of BMI1 mRNA
CTD
PMID:25523186
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
G
Brca1
BRCA1, DNA repair associated
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of BRCA1 mRNA Gold analog results in decreased expression of BRCA1 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
G
Brca2
BRCA2, DNA repair associated
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of BRCA2 mRNA Gold analog results in decreased expression of BRCA2 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
G
Bves
blood vessel epicardial substance
increases expression
ISO
Gold results in increased expression of BVES mRNA
CTD
PMID:29705079
NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
G
C1d
C1D nuclear receptor corepressor
decreases expression
ISO
Gold results in decreased expression of C1D mRNA
CTD
PMID:25523186
NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
G
C3
complement C3
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of C3 mRNA
CTD
PMID:28433809
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
G
C8h11orf54
similar to human chromosome 11 open reading frame 54
decreases expression
ISO
Gold results in decreased expression of C11ORF54 mRNA
CTD
PMID:25523186
NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
G
C9
complement C9
decreases expression
ISO
Gold analog results in decreased expression of C9 mRNA
CTD
PMID:36057382
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
G
Capza2
capping actin protein of muscle Z-line subunit alpha 2
decreases expression
ISO
Gold results in decreased expression of CAPZA2 mRNA
CTD
PMID:25523186
NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
G
Car13
carbonic anhydrase 13
decreases expression
ISO
Gold results in decreased expression of CA13 mRNA
CTD
PMID:25523186
NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
G
Casp1
caspase 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of CASP1 mRNA
CTD
PMID:28433809
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
G
Casp3
caspase 3
multiple interactions increases activity increases cleavage increases expression
ISO EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP3 mRNA; [Polyethyleneimine binds to Gold] which results in increased expression of CASP3 mRNA; [Quercetin analog co-treated with Gold analog] results in increased cleavage of CASP3 protein; [Quercetin analog co-treated with Gold analog] results in increased expression of and results in increased activity of CASP3 protein; Dexamethasone promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein] [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP3 protein Gold analog results in increased cleavage of CASP3 protein Gold results in increased expression of CASP3 mRNA
CTD
PMID:19760634 PMID:21621595 PMID:22178767 PMID:25846798 PMID:26551149 PMID:27470402 PMID:27836789 PMID:28433809 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Casp4
caspase 4
increases cleavage
ISO
Gold analog results in increased cleavage of CASP4 protein
CTD
PMID:26551149
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
G
Casp7
caspase 7
increases cleavage
ISO
Gold analog results in increased cleavage of CASP7 protein
CTD
PMID:26551149
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
G
Casp8
caspase 8
increases expression decreases expression
ISO
Gold results in increased expression of CASP8 mRNA Gold analog results in decreased expression of CASP8 mRNA
CTD
PMID:22178767 PMID:36057382
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Casp9
caspase 9
multiple interactions increases cleavage
ISO EXP
[Gold analog co-treated with Platinum] results in increased activity of CASP9 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP9 mRNA [Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP9 protein Gold analog results in increased cleavage of CASP9 protein
CTD
PMID:25846798 PMID:26551149 PMID:27836789
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cat
catalase
multiple interactions
ISO
[Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]
CTD
PMID:27836789
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cbx3
chromobox 3
decreases expression
ISO
Gold results in decreased expression of CBX3 mRNA
CTD
PMID:25523186
NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL2 protein Gold results in increased secretion of CCL2 protein
CTD
PMID:22155353
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl5
C-C motif chemokine ligand 5
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL5 protein Gold results in increased secretion of CCL5 protein
CTD
PMID:22155353
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
G
Ccl7
C-C motif chemokine ligand 7
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CCL7 protein Gold results in increased secretion of CCL7 protein
CTD
PMID:22155353
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
G
Ccnd1
cyclin D1
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased expression of CCND1 protein
CTD
PMID:27470402
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Cct5
chaperonin containing TCP1 subunit 5
decreases expression
ISO
Gold analog results in decreased expression of CCT5 protein
CTD
PMID:24780912
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
G
Cd19
CD19 molecule
increases expression
ISO
Gold analog results in increased expression of CD19 mRNA
CTD
PMID:36057382
NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
G
Cd36
CD36 molecule
decreases expression
ISO
Gold analog results in decreased expression of CD36 mRNA
CTD
PMID:36057382
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cd40
CD40 molecule
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CD40 mRNA
CTD
PMID:28433809
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd86
CD86 molecule
decreases expression
ISO
Gold analog results in decreased expression of CD86 mRNA
CTD
PMID:36057382
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
G
Cda
cytidine deaminase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of CDA mRNA
CTD
PMID:19695318
NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
G
Cdk1
cyclin-dependent kinase 1
decreases expression increases expression
ISO
Gold results in decreased expression of CDK1 mRNA Gold results in increased expression of CDK1 mRNA
CTD
PMID:25523186 PMID:29705079
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdk7
cyclin-dependent kinase 7
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CDK7 mRNA
CTD
PMID:19695318
NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions
ISO
[Gold binds to Dimethyldithiocarbamate] which results in increased expression of CDKN1B protein
CTD
PMID:17079469
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn2aip
CDKN2A interacting protein
decreases expression
ISO
Gold results in decreased expression of CDKN2AIP mRNA
CTD
PMID:25523186
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
G
Cgrrf1
cell growth regulator with ring finger domain 1
decreases expression
ISO
Gold results in decreased expression of CGRRF1 mRNA
CTD
PMID:25523186
NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
G
Chek1
checkpoint kinase 1
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CHEK1 mRNA Gold analog results in decreased expression of CHEK1 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
G
Chek2
checkpoint kinase 2
decreases expression
ISO
Gold analog results in decreased expression of CHEK2 mRNA
CTD
PMID:36057382
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
G
Chordc1
cysteine and histidine rich domain containing 1
decreases expression
ISO
Gold results in decreased expression of CHORDC1 mRNA
CTD
PMID:25523186
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
G
Cisd1
CDGSH iron sulfur domain 1
decreases expression
ISO
Gold results in decreased expression of CISD1 mRNA
CTD
PMID:25523186
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
G
Cldn12
claudin 12
decreases expression
ISO
Gold results in decreased expression of CLDN12 mRNA
CTD
PMID:25523186
NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
G
Cnbp
CCHC-type zinc finger, nucleic acid binding protein
decreases expression
ISO
Gold results in decreased expression of CNBP mRNA
CTD
PMID:25523186
NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
G
Cnot7
CCR4-NOT transcription complex, subunit 7
decreases expression
ISO
Gold results in decreased expression of CNOT7 mRNA
CTD
PMID:25523186
NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
G
Col1a1
collagen type I alpha 1 chain
increases expression
ISO
Gold analog results in increased expression of COL1A1 protein
CTD
PMID:24780912
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
Col1a2
collagen type I alpha 2 chain
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of COL1A2 mRNA
CTD
PMID:19695318
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
G
Col3a1
collagen type III alpha 1 chain
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of COL3A1 mRNA
CTD
PMID:19695318
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
G
Commd8
COMM domain containing 8
decreases expression
ISO
Gold results in decreased expression of COMMD8 mRNA
CTD
PMID:25523186
NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617
G
Cox11
cytochrome c oxidase copper chaperone COX11
decreases expression
ISO
Gold results in decreased expression of COX11 mRNA
CTD
PMID:25523186
NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322
G
Cox17
cytochrome c oxidase copper chaperone COX17
decreases expression
ISO
Gold results in decreased expression of COX17 mRNA
CTD
PMID:25523186
NCBI chr11:62,400,733...62,406,507
G
Cpt1a
carnitine palmitoyltransferase 1A
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CPT1A mRNA
CTD
PMID:28433809
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Cpt2
carnitine palmitoyltransferase 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CPT2 mRNA
CTD
PMID:28433809
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
G
Crot
carnitine O-octanoyltransferase
decreases expression
ISO
Gold analog results in decreased expression of CROT mRNA
CTD
PMID:36057382
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
G
Csf2
colony stimulating factor 2
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of CSF2 protein Gold results in increased secretion of CSF2 protein
CTD
PMID:22155353
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
G
Csf3
colony stimulating factor 3
increases secretion multiple interactions
ISO
Gold results in increased secretion of CSF3 protein [Gold co-treated with Silicon Dioxide] results in increased secretion of CSF3 protein
CTD
PMID:22155353
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
G
Ctcf
CCCTC-binding factor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of CTCF mRNA
CTD
PMID:19695318
NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
G
Cux1
cut-like homeobox 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of CUX1 mRNA
CTD
PMID:19695318
NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
G
Cxcl10
C-X-C motif chemokine ligand 10
increases secretion multiple interactions
ISO
Gold results in increased secretion of CXCL10 protein [Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL10 protein
CTD
PMID:22155353
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl2
C-X-C motif chemokine ligand 2
multiple interactions increases secretion
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL2 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL2 protein Gold results in increased secretion of CXCL2 protein
CTD
PMID:19695318 PMID:22155353
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL1 mRNA
CTD
PMID:19695318
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of CYCS protein
CTD
PMID:21621595
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases activity decreases expression multiple interactions
ISO
Gold analog results in increased activity of CYP1A1 protein Gold analog results in decreased expression of CYP1A1 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of CYP1A1 mRNA
CTD
PMID:20193702 PMID:28433809 PMID:36057382
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
increases expression
ISO
Gold results in increased expression of CYP24A1 mRNA
CTD
PMID:29705079
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of CYP2D6 mRNA Gold analog results in decreased expression of CYP2D6 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases expression
ISO
Gold analog results in decreased expression of CYP2E1 mRNA
CTD
PMID:36057382
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases expression
ISO
Gold analog results in increased expression of CYP7A1 mRNA
CTD
PMID:36057382
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cyth1
cytohesin 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of CYTH1 mRNA
CTD
PMID:19695318
NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
G
Dab2
DAB adaptor protein 2
increases expression
ISO
Gold results in increased expression of DAB2 mRNA
CTD
PMID:29705079
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
G
Dcp2
decapping mRNA 2
decreases expression
ISO
Gold results in decreased expression of DCP2 mRNA
CTD
PMID:25523186
NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
G
Ddc
dopa decarboxylase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of DDC mRNA
CTD
PMID:19695318
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of DDIT3 mRNA
CTD
PMID:28433809
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Ddit4
DNA-damage-inducible transcript 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of DDIT4 mRNA
CTD
PMID:19695318
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
G
Defb1
defensin beta 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DEFB1 mRNA
CTD
PMID:28433809
NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
G
Dhcr24
24-dehydrocholesterol reductase
multiple interactions decreases expression
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of DHCR24 mRNA Gold analog results in decreased expression of DHCR24 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of DHCR24 mRNA
CTD
PMID:19695318 PMID:28433809 PMID:36057382
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
G
Dld
dihydrolipoamide dehydrogenase
decreases expression
ISO
Gold analog results in decreased expression of DLD mRNA
CTD
PMID:36057382
NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
G
Dnah14
dynein axonemal heavy chain 14
decreases expression
ISO
Gold results in decreased expression of DNAH14 mRNA
CTD
PMID:25523186
NCBI chr13:93,322,653...93,540,706
Ensembl chr13:93,322,711...93,538,646
G
Dnaja3
DnaJ heat shock protein family (Hsp40) member A3
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of DNAJA3 mRNA
CTD
PMID:28433809
NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161
G
Dnajb14
DnaJ heat shock protein family (Hsp40) member B14
decreases expression
ISO
Gold results in decreased expression of DNAJB14 mRNA
CTD
PMID:25523186
NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490
G
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
decreases expression
ISO
Gold results in decreased expression of DNAJB6 mRNA
CTD
PMID:25523186
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
G
Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
decreases expression
ISO
Gold results in decreased expression of DNAJB9 mRNA
CTD
PMID:25523186
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
G
Dnajc10
DnaJ heat shock protein family (Hsp40) member C10
decreases expression
ISO
Gold results in decreased expression of DNAJC10 mRNA
CTD
PMID:25523186
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
G
Dnajc19
DnaJ heat shock protein family (Hsp40) member C19
decreases expression
ISO
Gold results in decreased expression of DNAJC19 mRNA
CTD
PMID:25523186
NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
G
Dnajc21
DnaJ heat shock protein family (Hsp40) member C21
decreases expression
ISO
Gold results in decreased expression of DNAJC21 mRNA
CTD
PMID:25523186
NCBI chr 2:59,419,507...59,446,746
Ensembl chr 2:59,419,510...59,446,752
G
Dnajc5
DnaJ heat shock protein family (Hsp40) member C5
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DNAJC5 mRNA
CTD
PMID:28433809
NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
G
Dpysl4
dihydropyrimidinase-like 4
increases expression
ISO
Gold analog results in increased expression of DPYSL4 mRNA
CTD
PMID:36057382
NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
G
Drd3
dopamine receptor D3
multiple interactions
EXP
Gold inhibits the reaction [3-N-methylspiperone binds to DRD3 protein]
CTD
PMID:10215675
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
G
Drd4
dopamine receptor D4
multiple interactions
EXP
Gold inhibits the reaction [3-N-methylspiperone binds to DRD4 protein]
CTD
PMID:10215675
NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
G
Dsc2
desmocollin 2
increases expression
ISO
Gold results in increased expression of DSC2 mRNA
CTD
PMID:29705079
NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
G
Dsg2
desmoglein 2
increases expression
ISO
Gold results in increased expression of DSG2 mRNA
CTD
PMID:29705079
NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
G
Duox1
dual oxidase 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DUOX1 mRNA
CTD
PMID:28433809
NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
G
Duox2
dual oxidase 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of DUOX2 mRNA
CTD
PMID:28433809
NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
G
Dusp1
dual specificity phosphatase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of DUSP1 mRNA
CTD
PMID:19695318
NCBI chr10:16,680,478...16,683,275
G
Dusp11
dual specificity phosphatase 11
decreases expression
ISO
Gold results in decreased expression of DUSP11 mRNA
CTD
PMID:25523186
NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
G
Dut
deoxyuridine triphosphatase
decreases expression
ISO
Gold results in decreased expression of DUT mRNA
CTD
PMID:25523186
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
G
Dzip3
DAZ interacting zinc finger protein 3
decreases expression
ISO
Gold results in decreased expression of DZIP3 mRNA
CTD
PMID:25523186
NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
G
Edem3
ER degradation enhancing alpha-mannosidase like protein 3
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of EDEM3 mRNA Gold analog results in decreased expression of EDEM3 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
G
Eea1
early endosome antigen 1
decreases expression
ISO
Gold results in decreased expression of EEA1 mRNA
CTD
PMID:25523186
NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
G
Eef1d
eukaryotic translation elongation factor 1 delta
decreases expression
ISO
Gold analog results in decreased expression of EEF1D protein
CTD
PMID:24780912
NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
G
Eef2
eukaryotic translation elongation factor 2
decreases expression
ISO
Gold analog results in decreased expression of EEF2 protein
CTD
PMID:24780912
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
G
Egf
epidermal growth factor
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]
CTD
PMID:27634460
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
CTD
PMID:27634460
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
decreases expression
ISO
Gold analog results in decreased expression of EHHADH mRNA
CTD
PMID:36057382
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
G
Eid1
EP300 interacting inhibitor of differentiation 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of EID1 mRNA
CTD
PMID:19695318
NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
G
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
decreases expression
ISO
Gold results in decreased expression of EIF1AX mRNA
CTD
PMID:25523186
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
G
Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases phosphorylation
ISO
Gold analog results in increased phosphorylation of EIF2AK3 protein
CTD
PMID:26551149
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
G
Eif4a2
eukaryotic translation initiation factor 4A2
decreases expression
ISO
Gold results in decreased expression of EIF4A2 mRNA
CTD
PMID:25523186
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
G
Eif4e
eukaryotic translation initiation factor 4E
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein
CTD
PMID:27470402
NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
G
Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein
CTD
PMID:27470402
NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024
G
Eif5b
eukaryotic translation initiation factor 5B
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of EIF5B mRNA Gold analog results in decreased expression of EIF5B mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
G
Eno1
enolase 1
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of ENO1 protein
CTD
PMID:24780912
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Ep300
E1A binding protein p300
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Polyethyleneimine binds to Gold] which results in decreased expression of EP300 mRNA; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]
CTD
PMID:27634460 PMID:28433809
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
G
Epgn
epithelial mitogen
increases expression
ISO
Gold results in increased expression of EPGN mRNA
CTD
PMID:29705079
NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806
G
Epha1
Eph receptor A1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of EPHA1 mRNA
CTD
PMID:19695318
NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
G
Ephx1
epoxide hydrolase 1
increases expression
ISO
Gold analog results in increased expression of EPHX1 mRNA
CTD
PMID:36057382
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Ercc2
ERCC excision repair 2, TFIIH core complex helicase subunit
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of ERCC2 mRNA
CTD
PMID:28433809
NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
G
Ercc6
ERCC excision repair 6, chromatin remodeling factor
decreases expression
ISO
Gold analog results in decreased expression of ERCC6 mRNA
CTD
PMID:36057382
NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
G
Ern1
endoplasmic reticulum to nucleus signaling 1
increases phosphorylation
ISO
Gold analog results in increased phosphorylation of ERN1 protein
CTD
PMID:26551149
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
G
Ern2
endoplasmic reticulum to nucleus signaling 2
increases expression
ISO
Gold analog results in increased expression of ERN2 mRNA
CTD
PMID:36057382
NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
G
Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
increases expression
ISO
Gold results in increased expression of ERO1A mRNA
CTD
PMID:29705079
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
G
Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
decreases expression
ISO
Gold results in decreased expression of ESCO2 mRNA
CTD
PMID:25523186
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
G
Esr1
estrogen receptor 1
decreases expression
ISO
Gold analog results in decreased expression of ESR1 mRNA
CTD
PMID:36057382
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Evi5
ecotropic viral integration site 5
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of EVI5 mRNA
CTD
PMID:19695318
NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
G
Evx1
even-skipped homeobox 1
increases expression
ISO
Gold results in increased expression of EVX1 mRNA
CTD
PMID:25523186
NCBI chr 4:81,416,590...81,420,967
Ensembl chr 4:81,416,590...81,420,967
G
Fancl
FA complementation group L
decreases expression
ISO
Gold results in decreased expression of FANCL mRNA
CTD
PMID:25523186
NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255
G
Fas
Fas cell surface death receptor
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of FAS mRNA Gold analog results in decreased expression of FAS mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fasn
fatty acid synthase
decreases expression
ISO
Gold analog results in decreased expression of FASN mRNA
CTD
PMID:36057382
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fgf1
fibroblast growth factor 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of FGF1 mRNA
CTD
PMID:19695318
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fh
fumarate hydratase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of FH mRNA
CTD
PMID:28433809
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
G
Fkbp9
FKBP prolyl isomerase 9
increases phosphorylation decreases expression
ISO
Gold analog results in increased phosphorylation of FKBP9 protein Gold analog results in decreased expression of FKBP9 protein
CTD
PMID:24780912
NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
G
Fmo5
flavin containing dimethylaniline monoxygenase 5
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of FMO5 mRNA
CTD
PMID:28433809
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression
ISO
[Gold co-treated with Silicon Dioxide] results in increased expression of FOS mRNA Gold results in increased expression of FOS mRNA
CTD
PMID:22155353
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fth1
ferritin heavy chain 1
increases expression
ISO
Gold results in increased expression of FTH1 mRNA
CTD
PMID:29705079
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Fyb1
FYN binding protein 1
increases expression
ISO
Gold results in increased expression of FYB1 mRNA
CTD
PMID:29705079
NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
G
Fzd4
frizzled class receptor 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of FZD4 mRNA
CTD
PMID:19695318
NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724
G
G2e3
G2/M-phase specific E3 ubiquitin protein ligase
decreases expression
ISO
Gold results in decreased expression of G2E3 mRNA
CTD
PMID:25523186
NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
G
Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
decreases expression
ISO
Gold results in decreased expression of GALNT1 mRNA
CTD
PMID:25523186
NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
G
Galnt5
polypeptide N-acetylgalactosaminyltransferase 5
decreases expression
ISO
Gold analog results in decreased expression of GALNT5 mRNA
CTD
PMID:36057382
NCBI chr 3:42,573,622...42,619,881
Ensembl chr 3:42,573,622...42,619,881
G
Ganc
glucosidase, alpha; neutral C
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of GANC mRNA
CTD
PMID:19695318
NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
decreases expression
ISO
Gold analog results in decreased expression of GAPDH protein
CTD
PMID:24780912
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gca
grancalcin
decreases expression
ISO
Gold results in decreased expression of GCA mRNA
CTD
PMID:25523186
NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
G
Gcdh
glutaryl-CoA dehydrogenase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of GCDH mRNA
CTD
PMID:28433809
NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
G
Gmps
guanine monophosphate synthase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of GMPS mRNA
CTD
PMID:19695318
NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
G
Gng10
G protein subunit gamma 10
decreases expression
ISO
Gold results in decreased expression of GNG10 mRNA
CTD
PMID:25523186
NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012 Ensembl chr 5:73,856,164...73,863,012
G
Got2
glutamic-oxaloacetic transaminase 2
decreases expression
ISO
Gold analog results in decreased expression of GOT2 protein
CTD
PMID:24780912
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
G
Gpr182
G protein-coupled receptor 182
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of GPR182 mRNA
CTD
PMID:19695318
NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210
G
Gpt
glutamic--pyruvic transaminase
multiple interactions decreases expression
ISO
[Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]; [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein] Gold analog results in decreased expression of GPT mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of GPT mRNA
CTD
PMID:27836789 PMID:28433809 PMID:36057382
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx2
glutathione peroxidase 2
increases expression
ISO
Gold analog results in increased expression of GPX2 mRNA; Gold results in increased expression of GPX2 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Gold analog results in increased expression of GPX3 mRNA
CTD
PMID:36057382
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Gsn
gelsolin
decreases expression increases degradation
ISO
Gold analog results in decreased expression of GSN protein Gold analog results in increased degradation of GSN protein
CTD
PMID:24780912 PMID:26551149
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gstm4
glutathione S-transferase mu 4
multiple interactions increases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of GSTM4 mRNA Gold analog results in increased expression of GSTM4 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
G
Haao
3-hydroxyanthranilate 3,4-dioxygenase
increases expression
ISO
Gold analog results in increased expression of HAAO mRNA
CTD
PMID:36057382
NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
G
Hat1
histone acetyltransferase 1
decreases expression
ISO
Gold results in decreased expression of HAT1 mRNA
CTD
PMID:25523186
NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
G
Havcr1
hepatitis A virus cellular receptor 1
multiple interactions
ISO
[Polyethylene Glycols binds to Gold] which results in increased expression of HAVCR1 protein; [Polyethyleneimine binds to Gold] which results in increased expression of HAVCR1 protein; [Thioctic Acid binds to Gold] which results in increased expression of HAVCR1 protein
CTD
PMID:28433809
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
G
Hcar2
hydroxycarboxylic acid receptor 2
increases expression
ISO
Gold results in increased expression of HCAR2 mRNA
CTD
PMID:29705079
NCBI chr12:32,726,252...32,728,238
Ensembl chr12:32,726,184...32,728,504
G
Hexb
hexosaminidase subunit beta
multiple interactions
EXP
[gold chloride results in increased abundance of Gold] which results in increased export of HEXB protein; [gold tetrachloride, acid results in increased abundance of Gold] which results in increased export of HEXB protein
CTD
PMID:21376117
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
G
Hmgb2
high mobility group box 2
decreases expression
ISO
Gold results in decreased expression of HMGB2 mRNA
CTD
PMID:25523186
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
G
Hmox1
heme oxygenase 1
increases expression
ISO
Gold results in increased expression of HMOX1 mRNA
CTD
PMID:25523186
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hoxa3
homeobox A3
decreases expression
ISO
Gold analog results in decreased expression of HOXA3 mRNA
CTD
PMID:36057382
NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
decreases expression
ISO
Gold results in decreased expression of HPRT1 mRNA
CTD
PMID:25523186
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hpx
hemopexin
decreases expression
ISO
Gold analog results in decreased expression of HPX mRNA
CTD
PMID:36057382
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
G
Hsbp1
heat shock factor binding protein 1
decreases expression
ISO
Gold results in decreased expression of HSBP1 mRNA
CTD
PMID:25523186
NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821
G
Hsf1
heat shock transcription factor 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of HSF1 mRNA
CTD
PMID:28433809
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
G
Hsp90ab1
heat shock protein 90 alpha family class B member 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSP90AB1 mRNA
CTD
PMID:19695318
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
G
Hspa13
heat shock protein family A (Hsp70) member 13
decreases expression
ISO
Gold results in decreased expression of HSPA13 mRNA
CTD
PMID:25523186
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1A mRNA
CTD
PMID:28433809
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1B mRNA
CTD
PMID:28433809
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
G
Hspa2
heat shock protein family A (Hsp70) member 2
decreases expression
ISO
Gold analog results in decreased expression of HSPA2 mRNA
CTD
PMID:36057382
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
G
Hspa4
heat shock protein family A (Hsp70) member 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPA4 mRNA
CTD
PMID:19695318
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
G
Hspa8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
Gold analog results in increased expression of HSPA8 protein
CTD
PMID:24780912
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hspa9
heat shock protein family A (Hsp70) member 9
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of HSPA9 mRNA
CTD
PMID:19695318
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPB1 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of HSPB1 mRNA
CTD
PMID:19695318 PMID:28433809
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Hspd1
heat shock protein family D (Hsp60) member 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of HSPD1 mRNA
CTD
PMID:28433809
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
G
Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
Gold results in increased expression of HTATIP2 mRNA
CTD
PMID:29705079
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
G
Htatsf1
HIV-1 Tat specific factor 1
decreases expression
ISO
Gold results in decreased expression of HTATSF1 mRNA
CTD
PMID:25523186
NCBI chr X:134,935,426...134,949,607
Ensembl chr X:134,935,426...134,949,607
G
Htra4
HtrA serine peptidase 4
decreases expression
ISO
Gold analog results in decreased expression of HTRA4 mRNA
CTD
PMID:36057382
NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
G
Hyou1
hypoxia up-regulated 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of HYOU1 mRNA
CTD
PMID:19695318
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
G
Idh1
isocitrate dehydrogenase (NADP(+)) 1
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of IDH1 protein
CTD
PMID:24780912
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
G
Idh3g
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of IDH3G mRNA
CTD
PMID:28433809
NCBI chr X:151,515,244...151,524,175
Ensembl chr X:151,515,247...151,524,171
G
Ifngr1
interferon gamma receptor 1
increases expression
ISO
Gold results in increased expression of IFNGR1 mRNA
CTD
PMID:29705079
NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
G
Igf1
insulin-like growth factor 1
multiple interactions
ISO
Gold inhibits the reaction [IGF1 protein binds to IGF1R protein]
CTD
PMID:9648927
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igf1r
insulin-like growth factor 1 receptor
multiple interactions
ISO
Gold inhibits the reaction [IGF1 protein binds to IGF1R protein]; Gold inhibits the reaction [IGF2 protein binds to IGF1R protein]
CTD
PMID:9648927
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
G
Igf2
insulin-like growth factor 2
multiple interactions
ISO
Gold inhibits the reaction [IGF2 protein binds to IGF1R protein]
CTD
PMID:9648927
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Ikzf2
IKAROS family zinc finger 2
decreases expression
ISO
Gold results in decreased expression of IKZF2 mRNA
CTD
PMID:25523186
NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867
G
Il10
interleukin 10
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of IL10 protein Gold results in increased secretion of IL10 protein
CTD
PMID:22155353
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il1a
interleukin 1 alpha
multiple interactions decreases expression increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein Gold analog results in decreased expression of IL1A mRNA Gold results in increased secretion of IL1A protein
CTD
PMID:22155353 PMID:36057382
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions decreases expression increases secretion
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of IL1B mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1B protein Gold analog results in decreased expression of IL1B mRNA Gold results in increased secretion of IL1B protein
CTD
PMID:19695318 PMID:22155353 PMID:36057382
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il4
interleukin 4
decreases expression
ISO
Gold analog results in decreased expression of IL4 mRNA
CTD
PMID:36057382
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
multiple interactions increases secretion
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of IL6 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL6 protein [Polyethylene Glycols binds to Gold] which results in increased expression of IL6 protein; [Polyethyleneimine binds to Gold] which results in increased expression of IL6 protein; [Thioctic Acid binds to Gold] which results in increased expression of IL6 protein Gold results in increased secretion of IL6 protein
CTD
PMID:19695318 PMID:22155353 PMID:28433809
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Il6r
interleukin 6 receptor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of IL6RA mRNA
CTD
PMID:19695318
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Impa1
inositol monophosphatase 1
decreases expression
ISO
Gold results in decreased expression of IMPA1 mRNA
CTD
PMID:25523186
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
G
Ipmk
inositol polyphosphate multikinase
decreases expression
ISO
Gold results in decreased expression of IPMK mRNA
CTD
PMID:25523186
NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
G
Iqgap2
IQ motif containing GTPase activating protein 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of IQGAP2 mRNA
CTD
PMID:19695318
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
G
Jag1
jagged canonical Notch ligand 1
decreases expression
ISO
Gold analog results in decreased expression of JAG1 mRNA
CTD
PMID:36057382
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
G
Jak2
Janus kinase 2
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein
CTD
PMID:27470402
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]
CTD
PMID:27634460
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Jup
junction plakoglobin
decreases expression
ISO
Gold analog results in decreased expression of JUP protein
CTD
PMID:24780912
NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
G
Khk
ketohexokinase
increases expression
ISO
Gold analog results in increased expression of KHK mRNA
CTD
PMID:36057382
NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
G
Kin
Kin17 DNA and RNA binding protein
decreases expression
ISO
Gold results in decreased expression of KIN mRNA
CTD
PMID:25523186
NCBI chr17:68,413,483...68,431,392
Ensembl chr17:68,413,486...68,423,845
G
Kitlg
KIT ligand
decreases expression
ISO
Gold results in decreased expression of KITLG mRNA
CTD
PMID:25523186
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
G
Krr1
KRR1, small subunit processome component homolog
decreases expression
ISO
Gold results in decreased expression of KRR1 mRNA
CTD
PMID:25523186
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
G
Kynu
kynureninase
increases expression
ISO
Gold results in increased expression of KYNU mRNA
CTD
PMID:29705079
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
G
Lacc1
laccase domain containing 1
increases expression
ISO
Gold results in increased expression of LACC1 mRNA
CTD
PMID:29705079
NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545
G
Lactb2
lactamase, beta 2
decreases expression
ISO
Gold results in decreased expression of LACTB2 mRNA
CTD
PMID:25523186
NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429
G
Larp1b
La ribonucleoprotein 1B
decreases expression
ISO
Gold results in decreased expression of LARP1B mRNA
CTD
PMID:25523186
NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896
G
Lif
LIF, interleukin 6 family cytokine
multiple interactions increases secretion
ISO
[Gold co-treated with Silicon Dioxide] results in increased secretion of LIF protein Gold results in increased secretion of LIF protein
CTD
PMID:22155353
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
G
Lig4
DNA ligase 4
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which affects the expression of LIG4 mRNA
CTD
PMID:28433809
NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
G
Lima1
LIM domain and actin binding 1
decreases expression
ISO
Gold results in decreased expression of LIMA1 mRNA
CTD
PMID:25523186
NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
G
Lman1
lectin, mannose-binding, 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of LMAN1 mRNA
CTD
PMID:19695318
NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
G
Lmna
lamin A/C
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of LMNA mRNA
CTD
PMID:28433809
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
G
Lmnb1
lamin B1
increases degradation
ISO
Gold analog results in increased degradation of LMNB1 protein
CTD
PMID:26551149
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
G
Lpgat1
lysophosphatidylglycerol acyltransferase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of LPGAT1 mRNA
CTD
PMID:19695318
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
G
Lratd1
LRAT domain containing 1
increases expression
ISO
Gold results in increased expression of LRATD1 mRNA
CTD
PMID:25523186
NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319
G
Lsm5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
decreases expression
ISO
Gold results in decreased expression of LSM5 mRNA
CTD
PMID:25523186
NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165 Ensembl chr 4:104,652,477...104,654,165
G
Lsm6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
decreases expression
ISO
Gold results in decreased expression of LSM6 mRNA
CTD
PMID:25523186
NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484 Ensembl chr19:42,114,032...42,116,484
G
Lss
lanosterol synthase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of LSS mRNA
CTD
PMID:28433809
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
G
Mad2l1
mitotic arrest deficient 2 like 1
decreases expression
ISO
Gold results in decreased expression of MAD2L1 mRNA
CTD
PMID:25523186
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
G
Map1b
microtubule-associated protein 1B
increases expression
ISO
Gold results in increased expression of MAP1B mRNA
CTD
PMID:29705079
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]]
CTD
PMID:27634460
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Mbnl2
muscleblind-like splicing regulator 2
decreases expression
ISO
Gold results in decreased expression of MBNL2 mRNA
CTD
PMID:25523186
NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
G
Mdh1b
malate dehydrogenase 1B
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of MDH1B mRNA Gold analog results in decreased expression of MDH1B mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933
G
Mdm2
MDM2 proto-oncogene
decreases expression
ISO
Gold analog results in decreased expression of MDM2 mRNA
CTD
PMID:36057382
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
G
Mecr
mitochondrial trans-2-enoyl-CoA reductase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of MECR mRNA
CTD
PMID:19695318
NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
G
Mefv
MEFV innate immunity regulator, pyrin
increases expression
ISO
Gold results in increased expression of MEFV mRNA
CTD
PMID:25523186
NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
G
Metap2
methionyl aminopeptidase 2
decreases expression
ISO
Gold analog results in decreased expression of METAP2 mRNA; Gold results in decreased expression of METAP2 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
G
Mki67
marker of proliferation Ki-67
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of MKI67 mRNA Gold analog results in decreased expression of MKI67 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
G
Mmgt1
membrane magnesium transporter 1
decreases expression
ISO
Gold results in decreased expression of MMGT1 mRNA
CTD
PMID:25523186
NCBI chr X:134,408,463...134,420,798
Ensembl chr X:134,408,466...134,420,729
G
Mmp3
matrix metallopeptidase 3
increases expression
ISO
Gold results in increased expression of MMP3 mRNA
CTD
PMID:24022940
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
G
Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]
CTD
PMID:27634460
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Mnat1
MNAT1 component of CDK activating kinase
decreases expression
ISO
Gold results in decreased expression of MNAT1 mRNA
CTD
PMID:25523186
NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
G
Mob1b
MOB kinase activator 1B
decreases expression
ISO
Gold results in decreased expression of MOB1B mRNA
CTD
PMID:25523186
NCBI chr14:19,333,058...19,365,845
Ensembl chr14:19,332,459...19,365,845
G
Mob4
MOB family member 4, phocein
decreases expression
ISO
Gold results in decreased expression of MOB4 mRNA
CTD
PMID:25523186
NCBI chr 9:56,617,374...56,641,336
Ensembl chr 9:56,617,368...56,641,329
G
Morc3
MORC family CW-type zinc finger 3
decreases expression
ISO
Gold results in decreased expression of MORC3 mRNA
CTD
PMID:25523186
NCBI chr11:33,151,906...33,194,650
Ensembl chr11:33,152,025...33,194,646
G
Mrpl3
mitochondrial ribosomal protein L3
decreases expression
ISO
Gold results in decreased expression of MRPL3 mRNA
CTD
PMID:25523186
NCBI chr 8:105,670,184...105,693,544
Ensembl chr 8:105,670,184...105,693,544
G
Mrps6
mitochondrial ribosomal protein S6
decreases expression
ISO
Gold results in decreased expression of MRPS6 mRNA
CTD
PMID:25523186
NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
G
Mt1-ps3
metallothionein 1, pseudogene 3
increases expression
ISO
Gold results in increased expression of MT1E mRNA
CTD
PMID:25523186
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
G
Mt2A
metallothionein 2A
increases expression
ISO
Gold results in increased expression of MT2A mRNA
CTD
PMID:25523186
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mthfr
methylenetetrahydrofolate reductase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of MTHFR mRNA
CTD
PMID:19695318
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
G
Mtmr6
myotubularin related protein 6
decreases expression
ISO
Gold results in decreased expression of MTMR6 mRNA
CTD
PMID:25523186
NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
G
Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of MTOR protein
CTD
PMID:27470402
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Mtss1
MTSS I-BAR domain containing 1
increases expression
ISO
Gold results in increased expression of MTSS1 mRNA
CTD
PMID:29705079
NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
G
Mttp
microsomal triglyceride transfer protein
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of MTTP mRNA
CTD
PMID:28433809
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
G
Mycl
MYCL proto-oncogene, bHLH transcription factor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of MYCL mRNA
CTD
PMID:19695318
NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
G
Mynn
myoneurin
decreases expression
ISO
Gold results in decreased expression of MYNN mRNA
CTD
PMID:25523186
NCBI chr 2:112,779,654...112,797,188
Ensembl chr 2:112,779,657...112,796,397
G
Napepld
N-acyl phosphatidylethanolamine phospholipase D
decreases expression
ISO
Gold results in decreased expression of NAPEPLD mRNA
CTD
PMID:25523186
NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
G
Nceh1
neutral cholesterol ester hydrolase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of NCEH1 mRNA
CTD
PMID:19695318
NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity increases expression
ISO
Gold results in increased activity of NFE2L2 promoter Gold analog results in increased expression of NFE2L2 mRNA; Gold analog results in increased expression of NFE2L2 protein
CTD
PMID:21643505 PMID:36057382
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkb1
nuclear factor kappa B subunit 1
decreases expression
ISO
Gold analog results in decreased expression of NFKB1 mRNA
CTD
PMID:36057382
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Nfkbid
NFKB inhibitor delta
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of NFKBID mRNA
CTD
PMID:19695318
NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
G
Nfkbiz
NFKB inhibitor zeta
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of NFKBIZ mRNA
CTD
PMID:19695318
NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
G
Nipbl
NIPBL, cohesin loading factor
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of NIPBL mRNA
CTD
PMID:19695318
NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
G
Nos2
nitric oxide synthase 2
increases expression
ISO
Gold results in increased expression of NOS2 protein
CTD
PMID:24022940
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nploc4
NPL4 homolog, ubiquitin recognition factor
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of NPLOC4 mRNA
CTD
PMID:28433809
NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
G
Npm1
nucleophosmin 1
decreases expression
ISO
Gold results in decreased expression of NPM1 mRNA
CTD
PMID:25523186
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
G
Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases expression
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of NQO1 mRNA Gold analog results in increased expression of NQO1 mRNA; Gold results in increased expression of NQO1 mRNA
CTD
PMID:28433809 PMID:29705079 PMID:36057382
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr0b2
nuclear receptor subfamily 0, group B, member 2
decreases expression
ISO
Gold analog results in decreased expression of NR0B2 mRNA
CTD
PMID:36057382
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
G
Nr4a1
nuclear receptor subfamily 4, group A, member 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of NR4A1 mRNA
CTD
PMID:19695318
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
G
Nrcam
neuronal cell adhesion molecule
increases expression
ISO
Gold results in increased expression of NRCAM mRNA
CTD
PMID:29705079
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
G
Nrip1
nuclear receptor interacting protein 1
increases expression
ISO
Gold results in increased expression of NRIP1 mRNA
CTD
PMID:29705079
NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
G
Ntn4
netrin 4
increases expression
ISO
Gold results in increased expression of NTN4 mRNA
CTD
PMID:29705079
NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
G
Nucb1
nucleobindin 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of NUCB1 mRNA
CTD
PMID:28433809
NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
G
Nudt1
nudix hydrolase 1
decreases expression
ISO
Gold analog results in decreased expression of NUDT1 mRNA
CTD
PMID:36057382
NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
G
Nudt12
nudix hydrolase 12
decreases expression
ISO
Gold results in decreased expression of NUDT12 mRNA
CTD
PMID:25523186
NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039
G
Nudt13
nudix hydrolase 13
decreases expression
ISO
Gold analog results in decreased expression of NUDT13 mRNA
CTD
PMID:36057382
NCBI chr15:4,001,787...4,022,404
Ensembl chr15:4,001,794...4,022,293
G
Nup210
nucleoporin 210
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of NUP210 mRNA
CTD
PMID:28433809
NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874
G
Obi1
ORC ubiquitin ligase 1
decreases expression
ISO
Gold results in decreased expression of OBI1 mRNA
CTD
PMID:25523186
NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
G
Odr4
odr-4 GPCR localization factor homolog
decreases expression
ISO
Gold results in decreased expression of ODR4 mRNA
CTD
PMID:25523186
NCBI chr13:62,369,109...62,424,287
Ensembl chr13:62,394,608...62,424,209
G
Ogdh
oxoglutarate dehydrogenase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of OGDH mRNA
CTD
PMID:28433809
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
G
Ogg1
8-oxoguanine DNA glycosylase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of OGG1 mRNA
CTD
PMID:28433809
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
G
Orc4
origin recognition complex, subunit 4
decreases expression
ISO
Gold results in decreased expression of ORC4 mRNA
CTD
PMID:25523186
NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824
G
Os9
OS9, endoplasmic reticulum lectin
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of OS9 mRNA
CTD
PMID:28433809
NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745
G
Osgin1
oxidative stress induced growth inhibitor 1
increases expression
ISO
Gold results in increased expression of OSGIN1 mRNA
CTD
PMID:25523186
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
G
P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
Gold analog results in decreased expression of P4HB protein
CTD
PMID:24780912
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions decreases expression
ISO
Organogold Compounds promotes the reaction [Gold binds to PARP1 protein] Gold analog results in decreased expression of PARP1 mRNA
CTD
PMID:21370912 PMID:36057382
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Pcbp1
poly(rC) binding protein 1
decreases expression
ISO
Gold analog results in decreased expression of PCBP1 protein
CTD
PMID:24780912
NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500
G
Pcca
propionyl-CoA carboxylase subunit alpha
decreases expression
ISO
Gold analog results in decreased expression of PCCA mRNA
CTD
PMID:36057382
NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
G
Pcgf5
polycomb group ring finger 5
decreases expression
ISO
Gold results in decreased expression of PCGF5 mRNA
CTD
PMID:25523186
NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
G
Pcgf6
polycomb group ring finger 6
decreases expression
ISO
Gold results in decreased expression of PCGF6 mRNA
CTD
PMID:25523186
NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
G
Pcna
proliferating cell nuclear antigen
decreases expression
ISO
Gold analog results in decreased expression of PCNA mRNA
CTD
PMID:36057382
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
G
Pde4b
phosphodiesterase 4B
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PDE4B mRNA
CTD
PMID:19695318
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
G
Per3
period circadian regulator 3
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of PER3 mRNA
CTD
PMID:19695318
NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
G
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
decreases expression
ISO
Gold results in decreased expression of PIGA mRNA
CTD
PMID:25523186
NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
G
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
decreases expression
ISO
Gold results in decreased expression of PIGF mRNA
CTD
PMID:25523186
NCBI chr 6:7,589,584...7,617,719
Ensembl chr 6:7,589,570...7,639,675
G
Pigk
phosphatidylinositol glycan anchor biosynthesis, class K
decreases expression
ISO
Gold results in decreased expression of PIGK mRNA
CTD
PMID:25523186
NCBI chr 2:241,630,021...241,715,493
Ensembl chr 2:241,630,053...241,716,134
G
Pigy
phosphatidylinositol glycan anchor biosynthesis, class Y
decreases expression
ISO
Gold results in decreased expression of PIGY mRNA
CTD
PMID:25523186
NCBI chr 8:20,689,621...20,691,863
Ensembl chr 8:20,689,502...20,692,585
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PIK3R1 mRNA
CTD
PMID:19695318
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
G
Pkm
pyruvate kinase M1/2
decreases expression
ISO
Gold analog results in decreased expression of PKM protein
CTD
PMID:24780912
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
G
Pla2g6
phospholipase A2 group VI
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PLA2G6 mRNA
CTD
PMID:19695318
NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
G
Plekhf2
pleckstrin homology and FYVE domain containing 2
decreases expression
ISO
Gold results in decreased expression of PLEKHF2 mRNA
CTD
PMID:25523186
NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
G
Plin3
perilipin 3
increases expression
ISO
Gold analog results in increased expression of PLIN3 protein
CTD
PMID:24780912
NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PMAIP1 mRNA
CTD
PMID:19695318
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
G
Polk
DNA polymerase kappa
decreases expression
ISO
Gold results in decreased expression of POLK mRNA
CTD
PMID:25523186
NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
G
Polr2k
RNA polymerase II, I and III subunit K
decreases expression
ISO
Gold results in decreased expression of POLR2K mRNA
CTD
PMID:25523186
NCBI chr 7:67,347,118...67,359,466
Ensembl chr 7:67,356,113...67,357,668
G
Popdc3
popeye domain containing 3
increases expression
ISO
Gold results in increased expression of POPDC3 mRNA
CTD
PMID:29705079
NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593
G
Por
cytochrome p450 oxidoreductase
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of POR mRNA
CTD
PMID:28433809
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ppp1cb
protein phosphatase 1 catalytic subunit beta
decreases expression
ISO
Gold results in decreased expression of PPP1CB mRNA
CTD
PMID:25523186
NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
G
Ppp2r1a
protein phosphatase 2 scaffold subunit A alpha
decreases expression
ISO
Gold analog results in decreased expression of PPP2R1A protein
CTD
PMID:24780912
NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
G
Ppp2r5e
protein phosphatase 2 regulatory subunit B', epsilon
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of PPP2R5E mRNA
CTD
PMID:19695318
NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
G
Prdx1
peroxiredoxin 1
decreases expression increases expression
ISO
Gold analog results in decreased expression of PRDX1 protein Gold analog results in increased expression of PRDX1 mRNA
CTD
PMID:24780912 PMID:36057382
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
G
Prrc2a
proline-rich coiled-coil 2A
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of PRRC2A mRNA
CTD
PMID:19695318
NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130
G
Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
Gold analog results in decreased expression of PSAT1 protein
CTD
PMID:24780912
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
G
Psmd14
proteasome 26S subunit, non-ATPase 14
decreases expression
ISO
Gold results in decreased expression of PSMD14 mRNA
CTD
PMID:25523186
NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
G
Ptbp2
polypyrimidine tract binding protein 2
decreases expression
ISO
Gold results in decreased expression of PTBP2 mRNA
CTD
PMID:25523186
NCBI chr 2:207,812,659...207,874,019
Ensembl chr 2:207,812,920...207,873,506
G
Ptgr1
prostaglandin reductase 1
increases expression
ISO
Gold results in increased expression of PTGR1 mRNA
CTD
PMID:29705079
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
G
Ptgr2
prostaglandin reductase 2
decreases expression
ISO
Gold results in decreased expression of PTGR2 mRNA
CTD
PMID:25523186
NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions increases expression
ISO
[Gold co-treated with Silicon Dioxide] results in increased expression of PTGS2 mRNA [Polyethyleneimine binds to Gold] which results in decreased expression of PTGS2 mRNA Gold results in increased expression of PTGS2 mRNA
CTD
PMID:22155353 PMID:28433809
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptprc
protein tyrosine phosphatase, receptor type, C
increases expression
ISO
Gold analog results in increased expression of PTPRC mRNA
CTD
PMID:36057382
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
G
Pts
6-pyruvoyl-tetrahydropterin synthase
decreases expression
ISO
Gold results in decreased expression of PTS mRNA
CTD
PMID:25523186
NCBI chr 8:50,870,838...50,877,869
Ensembl chr 8:50,870,841...50,877,869
G
Pvr
PVR cell adhesion molecule
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of PVR mRNA
CTD
PMID:28433809
NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
G
Rab11a
RAB11a, member RAS oncogene family
decreases expression
ISO
Gold results in decreased expression of RAB11A mRNA
CTD
PMID:25523186
NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
G
Rab18
RAB18, member RAS oncogene family
decreases expression
ISO
Gold results in decreased expression of RAB18 mRNA
CTD
PMID:25523186
NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
G
Rabggtb
Rab geranylgeranyltransferase subunit beta
decreases expression
ISO
Gold results in decreased expression of RABGGTB mRNA
CTD
PMID:25523186
NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
G
Rad51
RAD51 recombinase
decreases expression
ISO
Gold analog results in decreased expression of RAD51 mRNA
CTD
PMID:36057382
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
G
Rad51b
RAD51 paralog B
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of RAD51B mRNA
CTD
PMID:19695318
NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
G
Rai14
retinoic acid induced 14
increases expression
ISO
Gold results in increased expression of RAI14 mRNA
CTD
PMID:29705079
NCBI chr 2:59,546,284...59,682,687
Ensembl chr 2:59,546,284...59,681,971
G
Rb1cc1
RB1-inducible coiled-coil 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of RB1CC1 mRNA
CTD
PMID:19695318
NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
G
Rbm12
RNA binding motif protein 12
decreases expression
ISO
Gold results in decreased expression of RBM12 mRNA
CTD
PMID:25523186
NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915 Ensembl chr 3:144,611,623...144,629,915
G
Rbp1
retinol binding protein 1
increases expression
ISO
Gold results in increased expression of RBP1 mRNA
CTD
PMID:29705079
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
G
Rc3h1
ring finger and CCCH-type domains 1
decreases expression
ISO
Gold results in decreased expression of RC3H1 mRNA
CTD
PMID:25523186
NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
G
Rdx
radixin
decreases expression
ISO
Gold analog results in decreased expression of RDX mRNA
CTD
PMID:36057382
NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]
CTD
PMID:27634460
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rfk
riboflavin kinase
decreases expression
ISO
Gold results in decreased expression of RFK mRNA
CTD
PMID:25523186
NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438 Ensembl chr X:214,799,825...214,807,438
G
Rhou
ras homolog family member U
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of RHOU mRNA
CTD
PMID:19695318
NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
G
Rnf11
ring finger protein 11
decreases expression
ISO
Gold results in decreased expression of RNF11 mRNA
CTD
PMID:25523186
NCBI chr 5:124,212,433...124,243,125
Ensembl chr 5:124,212,445...124,234,750
G
Rnf13
ring finger protein 13
decreases expression
ISO
Gold results in decreased expression of RNF13 mRNA
CTD
PMID:25523186
NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801
G
Rnf138
ring finger protein 138
decreases expression
ISO
Gold results in decreased expression of RNF138 mRNA
CTD
PMID:25523186
NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
G
Rnf149
ring finger protein 149
decreases expression
ISO
Gold results in decreased expression of RNF149 mRNA
CTD
PMID:25523186
NCBI chr 9:41,826,825...41,854,381
Ensembl chr 9:41,830,233...41,854,279
G
Rnf2
ring finger protein 2
decreases expression
ISO
Gold results in decreased expression of RNF2 mRNA
CTD
PMID:25523186
NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
G
Rnft1
ring finger protein, transmembrane 1
decreases expression
ISO
Gold results in decreased expression of RNFT1 mRNA
CTD
PMID:25523186
NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778
G
Ro60
Ro60, Y RNA binding protein
decreases expression
ISO
Gold results in decreased expression of RO60 mRNA
CTD
PMID:25523186
NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
G
Rp2
RP2 activator of ARL3 GTPase
decreases expression
ISO
Gold results in decreased expression of RP2 mRNA
CTD
PMID:25523186
NCBI chr X:1,872,582...1,916,704
Ensembl chr X:1,873,306...1,916,688
G
Rps27l
ribosomal protein S27-like
decreases expression
ISO
Gold results in decreased expression of RPS27L mRNA
CTD
PMID:25523186
NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
G
Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions
ISO
[Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein
CTD
PMID:27470402
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
G
RT1-Db1
RT1 class II, locus Db1
increases expression
ISO
Gold analog results in increased expression of HLA-DRB1 mRNA
CTD
PMID:36057382
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
G
Rtn4
reticulon 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of RTN4 mRNA
CTD
PMID:19695318
NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
G
Sar1b
secretion associated, Ras related GTPase 1B
decreases expression
ISO
Gold results in decreased expression of SAR1B mRNA
CTD
PMID:25523186
NCBI chr10:36,024,415...36,054,069
Ensembl chr10:36,024,382...36,054,066
G
Sarnp
SAP domain containing ribonucleoprotein
decreases expression
ISO
Gold results in decreased expression of SARNP mRNA
CTD
PMID:25523186
NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332
G
Scoc
short coiled-coil protein
decreases expression
ISO
Gold results in decreased expression of SCOC mRNA
CTD
PMID:25523186
NCBI chr19:24,659,651...24,689,237
Ensembl chr19:24,659,651...24,693,217
G
Scp2
sterol carrier protein 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of SCP2 mRNA
CTD
PMID:19695318
NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
G
Sec23a
Sec23 homolog A, COPII coat complex component
decreases expression
ISO
Gold results in decreased expression of SEC23A mRNA
CTD
PMID:25523186
NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035
G
Sec24a
SEC24 homolog A, COPII coat complex component
decreases expression
ISO
Gold results in decreased expression of SEC24A mRNA
CTD
PMID:25523186
NCBI chr10:35,946,901...36,024,353
Ensembl chr10:35,947,031...36,024,353
G
Sel1l3
SEL1L family member 3
increases expression
ISO
Gold results in increased expression of SEL1L3 mRNA
CTD
PMID:29705079
NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
G
Selenot
selenoprotein T
decreases expression
ISO
Gold results in decreased expression of SELENOT mRNA
CTD
PMID:25523186
NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427
G
Septin8
septin 8
decreases expression
ISO
Gold analog results in decreased expression of SEPTIN8 protein
CTD
PMID:24780912
NCBI chr10:37,684,649...37,713,704
Ensembl chr10:37,684,639...37,713,174
G
Serp1
stress-associated endoplasmic reticulum protein 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of SERP1 mRNA
CTD
PMID:28433809
NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116
G
Serpine1
serpin family E member 1
increases expression
ISO
Gold results in increased expression of SERPINE1 mRNA
CTD
PMID:29705079
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Serpinh1
serpin family H member 1
decreases expression
ISO
Gold analog results in decreased expression of SERPINH1 protein
CTD
PMID:24780912
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
G
Sh3kbp1
SH3 domain-containing kinase-binding protein 1
increases expression
ISO
Gold results in increased expression of SH3KBP1 mRNA
CTD
PMID:29705079
NCBI chr X:34,877,862...35,223,013
Ensembl chr X:34,877,866...35,222,747
G
Slc25a24
solute carrier family 25 member 24
decreases expression
ISO
Gold analog results in decreased expression of SLC25A24 protein
CTD
PMID:24780912
NCBI chr 2:196,761,076...196,799,236
Ensembl chr 2:196,761,274...196,799,231
G
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`
decreases expression
ISO
Gold results in decreased expression of SMARCAD1 mRNA
CTD
PMID:25523186
NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563
G
Smc4
structural maintenance of chromosomes 4
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC4 mRNA
CTD
PMID:19695318
NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
G
Smc6
structural maintenance of chromosomes 6
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC6 mRNA
CTD
PMID:19695318
NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746
G
Snrpb2
small nuclear ribonucleoprotein polypeptide B2
decreases expression
ISO
Gold results in decreased expression of SNRPB2 mRNA
CTD
PMID:25523186
NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
G
Snx6
sorting nexin 6
decreases expression
ISO
Gold results in decreased expression of SNX6 mRNA
CTD
PMID:25523186
NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
G
Sod1
superoxide dismutase 1
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of SOD1 mRNA
CTD
PMID:19695318
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sp100
SP100 nuclear antigen
decreases expression
ISO
Gold results in decreased expression of SP100 mRNA
CTD
PMID:25523186
NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
G
Sp3
Sp3 transcription factor
decreases expression
ISO
Gold results in decreased expression of SP3 mRNA
CTD
PMID:25523186
NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
G
Spast
spastin
decreases expression
ISO
Gold results in decreased expression of SPAST mRNA
CTD
PMID:25523186
NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
G
Spata2
spermatogenesis associated 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of SPATA2 mRNA
CTD
PMID:28433809
NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705
G
Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions decreases expression
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA Gold analog results in decreased expression of SREBF1 mRNA
CTD
PMID:28433809 PMID:36057382
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
G
Srek1ip1
SREK1-interacting protein 1
decreases expression
ISO
Gold results in decreased expression of SREK1IP1 mRNA
CTD
PMID:25523186
NCBI chr 2:35,975,978...35,999,636
Ensembl chr 2:35,975,989...35,999,636
G
Srp9
signal recognition particle 9
decreases expression
ISO
Gold results in decreased expression of SRP9 mRNA
CTD
PMID:25523186
NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720
G
Srsf10
serine and arginine rich splicing factor 10
decreases expression
ISO
Gold results in decreased expression of SRSF10 mRNA
CTD
PMID:25523186
NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
G
Srsf3
serine and arginine rich splicing factor 3
decreases expression
ISO
Gold results in decreased expression of SRSF3 mRNA
CTD
PMID:25523186
NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
G
Srsf7
serine and arginine rich splicing factor 7
decreases expression
ISO
Gold results in decreased expression of SRSF7 mRNA
CTD
PMID:25523186
NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
G
Stat1
signal transducer and activator of transcription 1
multiple interactions increases expression
ISO
[Gold co-treated with Silicon Dioxide] results in increased expression of STAT1 mRNA Gold results in increased expression of STAT1 mRNA
CTD
PMID:22155353
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
G
Stat3
signal transducer and activator of transcription 3
increases expression multiple interactions
ISO
Gold results in increased expression of STAT3 mRNA [Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA
CTD
PMID:22155353
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stau2
staufen double-stranded RNA binding protein 2
decreases expression
ISO
Gold results in decreased expression of STAU2 mRNA
CTD
PMID:25523186
NCBI chr 5:2,840,741...3,084,935
Ensembl chr 5:2,840,765...3,084,929
G
Stbd1
starch binding domain 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of STBD1 mRNA
CTD
PMID:28433809
NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
G
Steap1
STEAP family member 1
decreases expression
ISO
Gold results in decreased expression of STEAP1 mRNA
CTD
PMID:25523186
NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
G
Stk26
serine/threonine kinase 26
decreases expression
ISO
Gold results in decreased expression of STK26 mRNA
CTD
PMID:25523186
NCBI chr X:130,325,064...130,375,674
Ensembl chr X:130,310,885...130,374,291
G
Sucla2
succinate-CoA ligase ADP-forming subunit beta
decreases expression
ISO
Gold analog results in decreased expression of SUCLA2 mRNA; Gold results in decreased expression of SUCLA2 mRNA
CTD
PMID:25523186 PMID:36057382
NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
G
Syt1
synaptotagmin 1
decreases expression
ISO
Gold analog results in decreased expression of SYT1 mRNA
CTD
PMID:36057382
NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
G
Syvn1
synoviolin 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of SYVN1 mRNA
CTD
PMID:28433809
NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
G
Tacstd2
tumor-associated calcium signal transducer 2
increases expression
ISO
Gold results in increased expression of TACSTD2 mRNA
CTD
PMID:29705079
NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
G
Tada1
transcriptional adaptor 1
decreases expression
ISO
Gold results in decreased expression of TADA1 mRNA
CTD
PMID:25523186
NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504
G
Taf9b
TATA-box binding protein associated factor 9b
decreases expression
ISO
Gold results in decreased expression of TAF9B mRNA
CTD
PMID:25523186
NCBI chr X:71,289,290...71,300,142
Ensembl chr X:71,289,290...71,300,604
G
Tagln
transgelin
decreases expression
ISO
Gold analog results in decreased expression of TAGLN mRNA
CTD
PMID:36057382
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
G
Tbl1xr1
TBL1X/Y related 1
decreases expression
ISO
Gold results in decreased expression of TBL1XR1 mRNA
CTD
PMID:25523186
NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055
G
Tcea1
transcription elongation factor A1
decreases expression
ISO
Gold results in decreased expression of TCEA1 mRNA
CTD
PMID:25523186
NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745 Ensembl chr15:14,631,454...14,668,745
G
Tdo2
tryptophan 2,3-dioxygenase
decreases expression
ISO
Gold results in decreased expression of TDO2 mRNA
CTD
PMID:25523186
NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
G
Tex30
testis expressed 30
decreases expression
ISO
Gold results in decreased expression of TEX30 mRNA
CTD
PMID:25523186
NCBI chr 9:46,243,416...46,252,273
Ensembl chr 9:46,242,748...46,252,249
G
Tfec
transcription factor EC
decreases expression
ISO
Gold results in decreased expression of TFEC mRNA
CTD
PMID:25523186
NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
G
Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
Gold results in increased expression of TFPI2 mRNA
CTD
PMID:29705079
NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TGFB1 mRNA
CTD
PMID:28433809
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
G
Thap1
THAP domain containing 1
decreases expression
ISO
Gold results in decreased expression of THAP1 mRNA
CTD
PMID:25523186
NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942
G
Tia1
TIA1 cytotoxic granule-associated RNA binding protein
decreases expression
ISO
Gold results in decreased expression of TIA1 mRNA
CTD
PMID:25523186
NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586
G
Tkt
transketolase
decreases expression
ISO
Gold analog results in decreased expression of TKT protein
CTD
PMID:24780912
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
G
Tlk1
tousled-like kinase 1
increases expression
ISO
Gold results in increased expression of TLK1 mRNA
CTD
PMID:29705079
NCBI chr 3:55,520,559...55,627,580
Ensembl chr 3:55,503,358...55,691,968
G
Tlr2
toll-like receptor 2
increases expression multiple interactions
ISO
Gold results in increased expression of TLR2 mRNA Gold promotes the reaction [SAA1 protein binds to TLR2 protein]
CTD
PMID:29705079
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
G
Tm4sf1
transmembrane 4 L six family member 1
increases expression
ISO
Gold results in increased expression of TM4SF1 mRNA
CTD
PMID:29705079
NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
G
Tmed10
transmembrane p24 trafficking protein 10
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in decreased expression of TMED10 mRNA
CTD
PMID:19695318
NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
G
Tnf
tumor necrosis factor
increases secretion multiple interactions
ISO
Gold results in increased secretion of TNF protein [Gold co-treated with Silicon Dioxide] results in increased secretion of TNF protein
CTD
PMID:22155353
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfaip3
TNF alpha induced protein 3
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of TNFAIP3 mRNA
CTD
PMID:19695318
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
G
Tnfaip8l1
TNF alpha induced protein 8 like 1
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TNFAIP8L1 mRNA
CTD
PMID:28433809
NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254
G
Tnfrsf10b
TNF receptor superfamily member 10b
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TNFRSF10A mRNA
CTD
PMID:28433809
NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
G
Tnfrsf1a
TNF receptor superfamily member 1A
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TNFRSF1A mRNA
CTD
PMID:28433809
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
G
Tnfsf10
TNF superfamily member 10
decreases expression
ISO
Gold analog results in decreased expression of TNFSF10 mRNA
CTD
PMID:36057382
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
G
Tp53
tumor protein p53
increases expression
ISO
Gold analog results in increased expression of TRP53 mRNA
CTD
PMID:22486372
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Tpt1
tumor protein, translationally-controlled 1
decreases expression
ISO
Gold analog results in decreased expression of TPT1 protein
CTD
PMID:24780912
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
G
Trim23
tripartite motif-containing 23
decreases expression
ISO
Gold results in decreased expression of TRIM23 mRNA
CTD
PMID:25523186
NCBI chr 2:35,302,405...35,335,746
Ensembl chr 2:35,302,409...35,335,743
G
Trmt13
tRNA methyltransferase 13 homolog
decreases expression
ISO
Gold results in decreased expression of TRMT13 mRNA
CTD
PMID:25523186
NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843
G
Trub1
TruB pseudouridine synthase family member 1
decreases expression
ISO
Gold results in decreased expression of TRUB1 mRNA
CTD
PMID:25523186
NCBI chr 1:256,513,418...256,554,549
Ensembl chr 1:256,515,562...256,552,814
G
Tuba1a
tubulin, alpha 1A
decreases expression
ISO
Gold analog results in decreased expression of TUBA1A protein
CTD
PMID:24780912
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
G
Tubb5
tubulin, beta 5 class I
decreases expression
ISO
Gold analog results in decreased expression of TUBB5 protein
CTD
PMID:24780912
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
G
Tufm
Tu translation elongation factor, mitochondrial
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of TUFM protein
CTD
PMID:24780912
NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
G
Txndc5
thioredoxin domain containing 5
multiple interactions
ISO
Gold analog results in decreased expression of and results in increased phosphorylation of TXNDC5 protein
CTD
PMID:24780912
NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
G
Txnip
thioredoxin interacting protein
decreases expression
ISO
Gold analog results in decreased expression of TXNIP mRNA
CTD
PMID:36057382
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
G
Txnrd1
thioredoxin reductase 1
decreases activity increases expression
EXP ISO
Gold results in decreased activity of TXNRD1 protein Gold results in increased expression of TXNRD1 mRNA
CTD
PMID:16510263 PMID:20851179 PMID:29705079
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
G
Txnrd2
thioredoxin reductase 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in decreased expression of TXNRD2 mRNA
CTD
PMID:28433809
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
G
Uap1l1
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
decreases expression
ISO
Gold analog results in decreased expression of UAP1L1 protein
CTD
PMID:24780912
NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443
G
Uba2
ubiquitin-like modifier activating enzyme 2
decreases expression
ISO
Gold results in decreased expression of UBA2 mRNA
CTD
PMID:25523186
NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682
G
Ube2g2
ubiquitin-conjugating enzyme E2G 2
decreases expression
ISO
Gold analog results in decreased expression of UBE2G2 mRNA
CTD
PMID:36057382
NCBI chr20:10,983,734...11,005,468
Ensembl chr20:10,983,742...11,005,447
G
Ube2h
ubiquitin-conjugating enzyme E2H
increases expression
ISO
Gold results in increased expression of UBE2H mRNA
CTD
PMID:29705079
NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156
G
Ube2n
ubiquitin-conjugating enzyme E2N
decreases expression
ISO
Gold results in decreased expression of UBE2N mRNA
CTD
PMID:25523186
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
G
Ube2w
ubiquitin-conjugating enzyme E2W
decreases expression
ISO
Gold results in decreased expression of UBE2W mRNA
CTD
PMID:25523186
NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965
G
Ucp2
uncoupling protein 2
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of UCP2 mRNA
CTD
PMID:28433809
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
decreases expression
ISO
Gold analog results in decreased expression of UGT1A1 mRNA
CTD
PMID:36057382
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt2a1
UDP glucuronosyltransferase family 2 member A1
decreases expression
ISO
Gold analog results in decreased expression of UGT2A1 mRNA
CTD
PMID:36057382
NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531
G
Uimc1
ubiquitin interaction motif containing 1
increases expression decreases expression
ISO
Gold results in increased expression of UIMC1 mRNA Gold results in decreased expression of UIMC1 mRNA
CTD
PMID:29705079
NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799
G
Upp2
uridine phosphorylase 2
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of UPP2 mRNA
CTD
PMID:19695318
NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
G
Usp1
ubiquitin specific peptidase 1
decreases expression
ISO
Gold results in decreased expression of USP1 mRNA
CTD
PMID:25523186
NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
G
Usp15
ubiquitin specific peptidase 15
decreases expression
ISO
Gold results in decreased expression of USP15 mRNA
CTD
PMID:25523186
NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
G
Usp16
ubiquitin specific peptidase 16
decreases expression
ISO
Gold results in decreased expression of USP16 mRNA
CTD
PMID:25523186
NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539
G
Usp33
ubiquitin specific peptidase 33
decreases expression
ISO
Gold results in decreased expression of USP33 mRNA
CTD
PMID:25523186
NCBI chr 2:241,283,209...241,328,479
Ensembl chr 2:241,292,985...241,328,479
G
Usp5
ubiquitin specific peptidase 5
decreases expression
ISO
Gold analog results in decreased expression of USP5 protein
CTD
PMID:24780912
NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
G
Vcl
vinculin
decreases expression
ISO
Gold analog results in decreased expression of VCL protein
CTD
PMID:24780912
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
G
Vim
vimentin
increases degradation
ISO
Gold analog results in increased degradation of VIM protein
CTD
PMID:26551149
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
G
Wbp4
WW domain binding protein 4
decreases expression
ISO
Gold results in decreased expression of WBP4 mRNA
CTD
PMID:25523186
NCBI chr15:54,862,700...54,890,668
Ensembl chr15:54,862,843...54,890,647
G
Wee1
WEE1 G2 checkpoint kinase
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of WEE1 mRNA
CTD
PMID:19695318
NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
G
Xpa
XPA, DNA damage recognition and repair factor
multiple interactions
ISO
[Polyethyleneimine binds to Gold] which results in increased expression of XPA mRNA
CTD
PMID:28433809
NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
G
Xpc
XPC complex subunit, DNA damage recognition and repair factor
decreases expression
ISO
Gold analog results in decreased expression of XPC mRNA
CTD
PMID:36057382
NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
G
Xrcc5
X-ray repair cross complementing 5
decreases expression
ISO
Gold analog results in decreased expression of XRCC5 mRNA
CTD
PMID:36057382
NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
G
Yod1
YOD1 deubiquitinase
decreases expression
ISO
Gold results in decreased expression of YOD1 mRNA
CTD
PMID:25523186
NCBI chr13:42,175,047...42,181,661
Ensembl chr13:42,174,820...42,177,205
G
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
multiple interactions
ISO
[Gold co-treated with Polyethylene Glycols] results in increased expression of YWHAG mRNA
CTD
PMID:19695318
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
G
Zbtb21
zinc finger and BTB domain containing 21
decreases expression
ISO
Gold results in decreased expression of ZBTB21 mRNA
CTD
PMID:25523186
NCBI chr11:37,312,337...37,327,040
Ensembl chr11:37,312,378...37,326,996
G
Zbtb41
zinc finger and BTB domain containing 41
decreases expression
ISO
Gold results in decreased expression of ZBTB41 mRNA
CTD
PMID:25523186
NCBI chr13:51,042,948...51,065,768
Ensembl chr13:51,042,948...51,065,768
G
Zc3h15
zinc finger CCCH-type containing 15
decreases expression
ISO
Gold results in decreased expression of ZC3H15 mRNA
CTD
PMID:25523186
NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333
G
Zcchc10
zinc finger CCHC-type containing 10
decreases expression
ISO
Gold results in decreased expression of ZCCHC10 mRNA
CTD
PMID:25523186
NCBI chr10:37,470,628...37,481,027
G
Zcchc9
zinc finger CCHC-type containing 9
decreases expression
ISO
Gold results in decreased expression of ZCCHC9 mRNA
CTD
PMID:25523186
NCBI chr 2:23,038,156...23,048,249
Ensembl chr 2:23,038,317...23,048,217
G
Zcrb1
zinc finger CCHC-type and RNA binding motif containing 1
decreases expression
ISO
Gold results in decreased expression of ZCRB1 mRNA
CTD
PMID:25523186
NCBI chr 7:124,525,227...124,538,564
Ensembl chr 7:124,524,870...124,571,261
G
Zdhhc17
zinc finger DHHC-type palmitoyltransferase 17
decreases expression
ISO
Gold results in decreased expression of ZDHHC17 mRNA
CTD
PMID:25523186
NCBI chr 7:46,369,963...46,433,691
Ensembl chr 7:46,369,988...46,433,764
G
Zdhhc20
zinc finger DHHC-type palmitoyltransferase 20
decreases expression
ISO
Gold results in decreased expression of ZDHHC20 mRNA
CTD
PMID:25523186
NCBI chr15:31,980,057...32,039,006
Ensembl chr15:31,983,155...32,038,989
G
Zfand1
zinc finger AN1-type containing 1
decreases expression
ISO
Gold results in decreased expression of ZFAND1 mRNA
CTD
PMID:25523186
NCBI chr 2:91,444,497...91,457,540
Ensembl chr 2:91,444,508...91,453,246
G
Zfand6
zinc finger AN1-type containing 6
decreases expression
ISO
Gold results in decreased expression of ZFAND6 mRNA
CTD
PMID:25523186
NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
G
Zfp277
zinc finger protein 277
decreases expression
ISO
Gold results in decreased expression of ZNF277 mRNA
CTD
PMID:25523186
NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:57,383,951...57,512,765
G
Zfp422
zinc finger protein 422
decreases expression
ISO
Gold results in decreased expression of ZNF22 mRNA
CTD
PMID:25523186
NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257
G
Zfyve16
zinc finger FYVE-type containing 16
decreases expression
ISO
Gold results in decreased expression of ZFYVE16 mRNA
CTD
PMID:25523186
NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990
G
Zmpste24
zinc metallopeptidase STE24
decreases expression
ISO
Gold results in decreased expression of ZMPSTE24 mRNA
CTD
PMID:25523186
NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
G
Zranb2
zinc finger RANBP2-type containing 2
decreases expression
ISO
Gold results in decreased expression of ZRANB2 mRNA
CTD
PMID:25523186
NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942
G
Zup1
zinc finger containing ubiquitin peptidase 1
decreases expression
ISO
Gold results in decreased expression of ZUP1 mRNA
CTD
PMID:25523186
NCBI chr20:30,785,226...30,815,377
Ensembl chr20:30,785,227...30,815,306
G
Ackr3
atypical chemokine receptor 3
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of ACKR3 mRNA
CTD
PMID:19192274
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
G
Adora2a
adenosine A2a receptor
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of ADORA2A mRNA
CTD
PMID:19192274
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
G
Amigo2
adhesion molecule with Ig like domain 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of AMIGO2 mRNA
CTD
PMID:19192274
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
G
Antxr1
ANTXR cell adhesion molecule 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of ANTXR1 mRNA
CTD
PMID:19192274
NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232
G
Aox1
aldehyde oxidase 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of AOX1 mRNA
CTD
PMID:19192274
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
G
Bcl2a1
BCL2-related protein A1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of BCL2A1 mRNA
CTD
PMID:19192274
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
G
Bst2
bone marrow stromal cell antigen 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of BST2 mRNA
CTD
PMID:19192274
NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
G
Ccl20
C-C motif chemokine ligand 20
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of CCL20 mRNA; Gold Sodium Thiomalate results in decreased expression of CCL20 protein
CTD
PMID:19192274
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
G
Ccn1
cellular communication network factor 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of CCN1 mRNA
CTD
PMID:19192274
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
G
Ccn5
cellular communication network factor 5
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of CCN5 mRNA
CTD
PMID:19192274
NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
G
Cd28
Cd28 molecule
multiple interactions affects response to substance
ISO
CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] CD28 protein affects the susceptibility to Gold Sodium Thiomalate
CTD
PMID:19077085
NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
G
Chuk
component of inhibitor of nuclear factor kappa B kinase complex
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein]
CTD
PMID:10820281
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
G
Clgn
calmegin
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of CLGN mRNA
CTD
PMID:19192274
NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
G
Col1a1
collagen type I alpha 1 chain
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of COL1A1 mRNA
CTD
PMID:19192274
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
Colec12
collectin sub-family member 12
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of COLEC12 mRNA
CTD
PMID:19192274
NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
G
Cxcl1
C-X-C motif chemokine ligand 1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA
CTD
PMID:19192274
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
G
Cxcl2
C-X-C motif chemokine ligand 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of CXCL2 mRNA
CTD
PMID:19192274
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
G
Cxcl3
C-X-C motif chemokine ligand 3
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA
CTD
PMID:19192274
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of CXCR4 mRNA
CTD
PMID:19192274
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Ddx10
DEAD-box helicase 10
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of DDX10 mRNA
CTD
PMID:19192274
NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
G
Dio1
iodothyronine deiodinase 1
decreases activity
ISO
Gold Sodium Thiomalate results in decreased activity of DIO1 protein
CTD
PMID:34662569
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
G
Efemp1
EGF containing fibulin extracellular matrix protein 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of EFEMP1 mRNA
CTD
PMID:19192274
NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of ENPP2 mRNA
CTD
PMID:19192274
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
G
Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of ENTPD3 mRNA
CTD
PMID:19192274
NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943
G
Fbl
fibrillarin
affects localization decreases activity multiple interactions
ISO
Gold Sodium Thiomalate affects the localization of FBL protein Gold Sodium Thiomalate results in decreased activity of FBL protein CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CTD
PMID:10942594 PMID:19077085
NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
G
Fbln1
fibulin 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of FBLN1 mRNA
CTD
PMID:19192274
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
G
Fgf7
fibroblast growth factor 7
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of FGF7 mRNA
CTD
PMID:19192274
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
G
Gbp1
guanylate binding protein 1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of GBP1 mRNA
CTD
PMID:19192274
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
G
Gpm6b
glycoprotein m6b
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of GPM6B mRNA
CTD
PMID:19192274
NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211
G
Gsdme
gasdermin E
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of GSDME mRNA
CTD
PMID:19192274
NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
G
Herc6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of HERC6 mRNA
CTD
PMID:19192274
NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744
G
Hilpda
hypoxia inducible lipid droplet-associated
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of HILPDA mRNA
CTD
PMID:19192274
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of HSD11B1 mRNA
CTD
PMID:19192274
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
G
Ifi27
interferon, alpha-inducible protein 27
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IFI27 mRNA
CTD
PMID:19192274
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
G
Ifi35
interferon-induced protein 35
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IFI35 mRNA
CTD
PMID:19192274
NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952
G
Ifi44
interferon-induced protein 44
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IFI44 mRNA
CTD
PMID:19192274
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
G
Ifi44l
interferon-induced protein 44-like
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IFI44L mRNA
CTD
PMID:19192274
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
G
Ifih1
interferon induced with helicase C domain 1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IFIH1 mRNA
CTD
PMID:19192274
NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
G
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IFIT3 mRNA
CTD
PMID:19192274
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
G
Ifng
interferon gamma
multiple interactions affects response to substance
ISO
IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] IFNG protein affects the susceptibility to Gold Sodium Thiomalate
CTD
PMID:19077085
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Ikbkb
inhibitor of nuclear factor kappa B kinase subunit beta
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein]
CTD
PMID:10820281
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
G
Il10
interleukin 10
multiple interactions
ISO
[Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL10 protein
CTD
PMID:11824965
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il1b
interleukin 1 beta
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES]
CTD
PMID:16393772 PMID:25314295
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1rn
interleukin 1 receptor antagonist
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IL1RN mRNA
CTD
PMID:19192274
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
G
Il23a
interleukin 23 subunit alpha
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IL23A mRNA
CTD
PMID:19192274
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
G
Il4
interleukin 4
multiple interactions affects response to substance
ISO
IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] IL4 protein affects the susceptibility to Gold Sodium Thiomalate
CTD
PMID:19077085
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
multiple interactions decreases expression affects response to substance
ISO
[Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL6 protein Gold Sodium Thiomalate results in decreased expression of IL6 mRNA; Gold Sodium Thiomalate results in decreased expression of IL6 protein IL6 protein affects the susceptibility to Gold Sodium Thiomalate IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CTD
PMID:11824965 PMID:19077085 PMID:19192274
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Irf7
interferon regulatory factor 7
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of IRF7 mRNA
CTD
PMID:19192274
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
G
Isg15
ISG15 ubiquitin-like modifier
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of ISG15 mRNA
CTD
PMID:19192274
NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
G
Isg20
interferon stimulated exonuclease gene 20
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of ISG20 mRNA
CTD
PMID:19192274
NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
G
Lamb3
laminin subunit beta 3
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of LAMB3 mRNA
CTD
PMID:19192274
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
G
Lxn
latexin
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of LXN mRNA
CTD
PMID:19192274
NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460
G
Ly6e
lymphocyte antigen 6 family member E
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of LY6E mRNA
CTD
PMID:19192274
NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
G
Marcks
myristoylated alanine rich protein kinase C substrate
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of MARCKS mRNA
CTD
PMID:19192274
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
G
Met
MET proto-oncogene, receptor tyrosine kinase
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of MET mRNA
CTD
PMID:19192274
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
G
Mir99b
microRNA 99b
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased expression of MIR99B mRNA]
CTD
PMID:33109608
NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
G
Mmp10
matrix metallopeptidase 10
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of MMP10 mRNA
CTD
PMID:19192274
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
G
Mx1
MX dynamin like GTPase 1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of MX1 mRNA
CTD
PMID:19192274
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
G
Ndufa4l2
NDUFA4, mitochondrial complex associated like 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of NDUFA4L2 mRNA
CTD
PMID:19192274
NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010
G
Nmb
neuromedin B
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of NMB mRNA
CTD
PMID:19192274
NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]
CTD
PMID:16393772
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nr4a3
nuclear receptor subfamily 4, group A, member 3
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of NR4A3 mRNA
CTD
PMID:19192274
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
G
Oas1a
2'-5' oligoadenylate synthetase 1A
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of OAS1 mRNA
CTD
PMID:19192274
NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
G
Oasl
2'-5'-oligoadenylate synthetase-like
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of OASL mRNA
CTD
PMID:19192274
NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
G
Olfml2b
olfactomedin-like 2B
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of OLFML2B mRNA
CTD
PMID:19192274
NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
G
Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of PHGDH mRNA
CTD
PMID:19192274
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
G
Plpp3
phospholipid phosphatase 3
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of PLPP3 mRNA
CTD
PMID:19192274
NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
G
Ppp4r2
protein phosphatase 4, regulatory subunit 2
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of PPP4R2 mRNA
CTD
PMID:19192274
NCBI chr 4:133,454,555...133,495,486
Ensembl chr 4:133,454,555...133,495,486
G
Ptges
prostaglandin E synthase
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES]
CTD
PMID:25314295
NCBI chr 3:14,177,892...14,189,236
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of PTGS2 mRNA
CTD
PMID:19192274
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Rarres1
retinoic acid receptor responder 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of RARRES1 mRNA
CTD
PMID:19192274
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]
CTD
PMID:33109608
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rgs4
regulator of G-protein signaling 4
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of RGS4 mRNA
CTD
PMID:19192274
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
G
Rig1
RNA sensor RIG-1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of RIGI mRNA
CTD
PMID:19192274
NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
G
Ripk2
receptor-interacting serine-threonine kinase 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of RIPK2 mRNA
CTD
PMID:19192274
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
Rnf19b
ring finger protein 19B
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of RNF19B mRNA
CTD
PMID:19192274
NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380
G
Rsad2
radical S-adenosyl methionine domain containing 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of RSAD2 mRNA
CTD
PMID:19192274
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
G
Slc7a11
solute carrier family 7 member 11
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of SLC7A11 mRNA
CTD
PMID:19192274
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
G
Sms
spermine synthase
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of SMS mRNA
CTD
PMID:19192274
NCBI chr X:37,516,949...37,572,657
Ensembl chr X:37,516,931...37,570,822
G
Sod2
superoxide dismutase 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of SOD2 mRNA
CTD
PMID:19192274
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Spon1
spondin 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of SPON1 mRNA
CTD
PMID:19192274
NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
G
Stat1
signal transducer and activator of transcription 1
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of STAT1 mRNA
CTD
PMID:19192274
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
G
Sts
steroid sulfatase
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of STS mRNA
CTD
PMID:19192274
NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
G
Thbs1
thrombospondin 1
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of THBS1 mRNA
CTD
PMID:19192274
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
G
Thbs2
thrombospondin 2
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of THBS2 mRNA
CTD
PMID:19192274
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
G
Tlr2
toll-like receptor 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of TLR2 mRNA
CTD
PMID:19192274
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
G
Tnfaip2
TNF alpha induced protein 2
decreases expression
ISO
Gold Sodium Thiomalate results in decreased expression of TNFAIP2 mRNA
CTD
PMID:19192274
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
G
Txnip
thioredoxin interacting protein
increases expression
ISO
Gold Sodium Thiomalate results in increased expression of TXNIP mRNA
CTD
PMID:19192274
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
G
Txnrd1
thioredoxin reductase 1
multiple interactions decreases activity
ISO EXP
Gold Sodium Thiomalate inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid] Gold Sodium Thiomalate results in decreased activity of TXNRD1 protein
CTD
PMID:16510263 PMID:17229725
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
G
Txnrd2
thioredoxin reductase 2
decreases activity
EXP
Gold Sodium Thiomalate results in decreased activity of TXNRD2 protein
CTD
PMID:15458826
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
G
Alb
albumin
affects binding
ISO
Gold Sodium Thiosulfate binds to ALB protein
CTD
PMID:16791640
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Cd40
CD40 molecule
increases expression
ISO
Gold Sodium Thiosulfate results in increased expression of CD40 protein
CTD
PMID:25458486
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Il6
interleukin 6
increases secretion
ISO
Gold Sodium Thiosulfate results in increased secretion of IL6 protein
CTD
PMID:25458486
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Tlr3
toll-like receptor 3
multiple interactions
ISO
TLR3 protein affects the reaction [Gold Sodium Thiosulfate results in increased secretion of CXCL8 protein]
CTD
PMID:25458486
NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
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