Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of EVI5 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EVI5 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of EVI5 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of EVI5 mRNA | CTD | PMID:32145629 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Metribolone results in increased expression of EVI5 mRNA | CTD | PMID:16751804 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Evi5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of EVI5 mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EVI5 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of EVI5 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of EVI5 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Evi5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of EVI5 mRNA | CTD | PMID:21570461 and PMID:24680724 | 2-palmitoylglycerol | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of EVI5 mRNA | CTD | PMID:37199045 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of EVI5 mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | Evi5 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of EVI5 promoter | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | EVI5 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of EVI5 gene | CTD | PMID:31601247 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of EVI5 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of EVI5 mRNA | CTD | PMID:27153756 | aristolochic acid A | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of EVI5 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | EVI5 (Homo sapiens) | 6480464 | Arsenic affects the methylation of EVI5 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | EVI5 (Homo sapiens) | 6480464 | Arsenic affects the methylation of EVI5 gene | CTD | PMID:25304211 | benzo[a]pyrene | increases expression | ISO | Evi5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of EVI5 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | Evi5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of EVI5 intron | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | EVI5 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of EVI5 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of EVI5 mRNA | CTD | PMID:15034205 | benzo[a]pyrene | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of EVI5 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of EVI5 mRNA | CTD | PMID:20064835 more ... | bisphenol A | decreases methylation | ISO | Evi5 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of EVI5 promoter | CTD | PMID:27312807 | bisphenol A | decreases methylation | ISO | EVI5 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of EVI5 gene | CTD | PMID:31601247 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of EVI5 mRNA | CTD | PMID:32145629 | calcitriol | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of EVI5 mRNA | CTD | PMID:16002434 | carbon nanotube | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of EVI5 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | EVI5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to EVI5 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Evi5 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of EVI5 mRNA | CTD | PMID:37019170 | cisplatin | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of EVI5 mRNA | CTD | PMID:27594783 | colforsin daropate hydrochloride | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Colforsin results in increased expression of EVI5 mRNA | CTD | PMID:16751804 | copper(II) sulfate | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of EVI5 mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of EVI5 mRNA | CTD | PMID:19167446 | CU-O LINKAGE | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | cupric oxide results in decreased expression of EVI5 mRNA | CTD | PMID:22077320 | diclofenac | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | Diclofenac results in decreased expression of EVI5 mRNA | CTD | PMID:35537566 | elemental selenium | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Selenium results in decreased expression of EVI5 mRNA | CTD | PMID:19244175 | epoxiconazole | increases expression | ISO | Evi5 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of EVI5 mRNA | CTD | PMID:35436446 | FR900359 | affects phosphorylation | ISO | EVI5 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of EVI5 protein | CTD | PMID:37730182 | geldanamycin | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of EVI5 mRNA | CTD | PMID:26705709 | gold atom | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | [Gold co-treated with Polyethylene Glycols] results in decreased expression of EVI5 mRNA | CTD | PMID:19695318 | gold(0) | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | [Gold co-treated with Polyethylene Glycols] results in decreased expression of EVI5 mRNA | CTD | PMID:19695318 | hydrogen peroxide | affects expression | ISO | EVI5 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of EVI5 mRNA | CTD | PMID:21179406 | mercury dichloride | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of EVI5 mRNA | CTD | PMID:27188386 | methotrexate | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of EVI5 mRNA | CTD | PMID:24449571 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of EVI5 gene | CTD | PMID:35440735 | mitoxantrone | affects response to substance | ISO | EVI5 (Homo sapiens) | 6480464 | EVI5 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EVI5 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | EVI5 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of EVI5 mRNA | CTD | PMID:35430440 | paracetamol | affects expression | ISO | Evi5 (Mus musculus) | 6480464 | Acetaminophen affects the expression of EVI5 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of EVI5 mRNA | CTD | PMID:22230336 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of EVI5 mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EVI5 mRNA | CTD | PMID:36331819 | phenobarbital | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of EVI5 mRNA | CTD | PMID:23091169 | pirinixic acid | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of EVI5 mRNA | CTD | PMID:18445702 | propiconazole | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | propiconazole results in decreased expression of EVI5 mRNA | CTD | PMID:21278054 | selenium atom | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Selenium results in decreased expression of EVI5 mRNA | CTD | PMID:19244175 | silicon dioxide | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of EVI5 mRNA | CTD | PMID:19073995 and PMID:23221170 | sodium arsenate | increases expression | ISO | Evi5 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of EVI5 mRNA | CTD | PMID:21795629 | sodium arsenate | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of EVI5 mRNA | CTD | PMID:21795629 | sodium arsenite | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of EVI5 mRNA | CTD | PMID:29301061 | succimer | multiple interactions | ISO | Evi5 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of EVI5 mRNA | CTD | PMID:21641980 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of EVI5 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of EVI5 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of EVI5 mRNA | CTD | PMID:31150632 | thimerosal | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of EVI5 mRNA | CTD | PMID:27188386 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of EVI5 mRNA | CTD | PMID:34492290 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of EVI5 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EVI5 mRNA | CTD | PMID:25729387 | trichostatin A | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of EVI5 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | affects expression | ISO | EVI5 (Homo sapiens) | 6480464 | trichostatin A affects the expression of EVI5 mRNA | CTD | PMID:28542535 | trovafloxacin | decreases expression | ISO | Evi5 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of EVI5 mRNA | CTD | PMID:35537566 | uranium atom | affects expression | ISO | EVI5 (Homo sapiens) | 6480464 | Uranium affects the expression of EVI5 mRNA | CTD | PMID:15672453 | urethane | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Urethane results in increased expression of EVI5 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of EVI5 mRNA | CTD | PMID:24935251 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of EVI5 mRNA | CTD | PMID:29427782 | vitamin E | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of EVI5 mRNA | CTD | PMID:19244175 | vorinostat | decreases expression | ISO | EVI5 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of EVI5 mRNA | CTD | PMID:27188386 | |