Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Spata2 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of SPATA2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | Spata2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SPATA2 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:27291303 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Spata2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SPATA2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SPATA2 mRNA | CTD | PMID:33387578 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SPATA2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SPATA2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Spata2 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of SPATA2 exon | CTD | PMID:33297965 | all-trans-retinoic acid | decreases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SPATA2 mRNA | CTD | PMID:33167477 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SPATA2 mRNA | CTD | PMID:16483693 | arsane | affects methylation | ISO | SPATA2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of SPATA2 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | SPATA2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of SPATA2 gene | CTD | PMID:25304211 | atrazine | decreases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SPATA2 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases methylation | ISO | SPATA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SPATA2 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SPATA2 promoter | CTD | PMID:23359474 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SPATA2 promoter | CTD | PMID:23359474 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SPATA2 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SPATA2 mRNA | CTD | PMID:25181051 | bisphenol F | multiple interactions | ISO | SPATA2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SPATA2 mRNA | CTD | PMID:28628672 | butanal | decreases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of SPATA2 mRNA | CTD | PMID:26079696 | chlorpyrifos | affects expression | EXP | | 6480464 | Chlorpyrifos affects the expression of SPATA2 mRNA | CTD | PMID:26775027 | chlorpyrifos | increases expression | ISO | Spata2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SPATA2 mRNA | CTD | PMID:27737797 | copper(II) sulfate | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SPATA2 mRNA | CTD | PMID:19549813 | coumarin | affects phosphorylation | ISO | SPATA2 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of SPATA2 protein | CTD | PMID:35688186 | cypermethrin | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | cypermethrin results in increased expression of SPATA2 mRNA | CTD | PMID:27704156 | dexamethasone | multiple interactions | ISO | SPATA2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SPATA2 mRNA | CTD | PMID:28628672 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SPATA2 promoter | CTD | PMID:23359474 | dicrotophos | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of SPATA2 mRNA | CTD | PMID:28302478 | dimethylarsinous acid | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | dimethylarsinous acid results in increased expression of SPATA2 mRNA | CTD | PMID:23487506 | diquat | decreases expression | ISO | Spata2 (Mus musculus) | 6480464 | Diquat results in decreased expression of SPATA2 protein | CTD | PMID:36851058 | doxorubicin | decreases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SPATA2 mRNA | CTD | PMID:29803840 | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of SPATA2 protein | CTD | PMID:36195186 | doxorubicin | increases expression | ISO | Spata2 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of SPATA2 protein | CTD | PMID:36195186 | ethanol | affects splicing | ISO | Spata2 (Mus musculus) | 6480464 | Ethanol affects the splicing of SPATA2 mRNA | CTD | PMID:30319688 | flavonoids | decreases expression | EXP | | 6480464 | Flavonoids results in decreased expression of SPATA2 mRNA | CTD | PMID:18035473 | folic acid | decreases expression | ISO | Spata2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SPATA2 mRNA | CTD | PMID:25629700 | folic acid | multiple interactions | ISO | Spata2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SPATA2 mRNA | CTD | PMID:22206623 | FR900359 | decreases phosphorylation | ISO | SPATA2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of SPATA2 protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SPATA2 mRNA | CTD | PMID:33387578 | gold atom | multiple interactions | ISO | SPATA2 (Homo sapiens) | 6480464 | [Polyethyleneimine binds to Gold] which results in decreased expression of SPATA2 mRNA | CTD | PMID:28433809 | gold(0) | multiple interactions | ISO | SPATA2 (Homo sapiens) | 6480464 | [Polyethyleneimine binds to Gold] which results in decreased expression of SPATA2 mRNA | CTD | PMID:28433809 | indometacin | multiple interactions | ISO | SPATA2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SPATA2 mRNA | CTD | PMID:28628672 | leflunomide | decreases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of SPATA2 mRNA | CTD | PMID:28988120 | paracetamol | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SPATA2 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SPATA2 mRNA | CTD | PMID:33387578 | sunitinib | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SPATA2 mRNA | CTD | PMID:31533062 | tamoxifen | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Tamoxifen results in increased expression of SPATA2 mRNA | CTD | PMID:15590111 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of SPATA2 mRNA | CTD | PMID:31150632 | thimerosal | decreases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of SPATA2 mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SPATA2 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SPATA2 mRNA | CTD | PMID:33387578 | urethane | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Urethane results in increased expression of SPATA2 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SPATA2 mRNA | CTD | PMID:23179753 and PMID:29154799 | valproic acid | affects expression | ISO | SPATA2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SPATA2 mRNA | CTD | PMID:25979313 | zearalenone | decreases expression | ISO | Spata2 (Mus musculus) | 6480464 | Zearalenone results in decreased expression of SPATA2 mRNA | CTD | PMID:24412631 | |