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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:29287
Term: gold atom
Definition: A copper group element atom that has formula Au.
Chemical ID: MESH:D006046
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1decreases expressionISOCYP1A1 (Homo sapiens)6480464CTDGold analog results in decreased expression of CYP1A1 mRNAPMID:36057382
Cyp1a1increases activityISOCyp1a1 (Mus musculus)6480464CTDGold analog results in increased activity of CYP1A1 proteinPMID:20193702
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTD[Polyethyleneimine binds to Gold] which results in decreased expression of CYP1A1 mRNAPMID:28433809
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