Arl1 (ADP-ribosylation factor like GTPase 1) - Rat Genome Database

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Gene: Arl1 (ADP-ribosylation factor like GTPase 1) Rattus norvegicus
Analyze
Symbol: Arl1
Name: ADP-ribosylation factor like GTPase 1
RGD ID: 621326
Description: Predicted to enable several functions, including GTP binding activity; GTPase activity; and phospholipase D activator activity. Involved in Golgi organization and Golgi vesicle transport. Located in trans-Golgi network. Orthologous to human ARL1 (ADP ribosylation factor like GTPase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor-like 1; ADP-ribosylation factor-like protein 1; MGC72836
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8725,007,401 - 25,018,572 (+)NCBIGRCr8
mRatBN7.2723,120,004 - 23,131,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl723,119,589 - 23,131,898 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx725,114,566 - 25,125,737 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,277,268 - 27,288,441 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,054,306 - 27,065,479 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,282,411 - 29,293,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,282,305 - 29,293,399 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0729,384,788 - 29,395,708 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,403,921 - 25,416,168 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1725,424,112 - 25,437,189 (+)NCBI
Celera720,279,124 - 20,290,252 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chloroacetaldehyde  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clodronic acid  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (EXP,ISO)
deguelin  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
Erionite  (ISO)
ethanol  (ISO)
fenofibrate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
gentamycin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
metformin  (EXP)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
propiconazole  (ISO)
raloxifene  (EXP)
resveratrol  (ISO)
rotenone  (EXP,ISO)
sodium fluoride  (ISO)
sulindac  (EXP)
tauroursodeoxycholic acid  (EXP)
thapsigargin  (ISO)
tolcapone  (EXP)
trichloroethene  (EXP)
triptonide  (ISO)
tunicamycin  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO,ISS)
cytosol  (IEA)
Golgi apparatus  (IBA,IEA,ISO,ISS)
Golgi membrane  (IEA)
trans-Golgi network  (IDA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Regulation of Golgi structure and function by ARF-like protein 1 (Arl1). Lu L, etal., J Cell Sci 2001 Dec;114(Pt 24):4543-55.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells. Schurmann A, etal., J Biol Chem 1994 Jun 3;269(22):15683-8.
Additional References at PubMed
PMID:8798635   PMID:9624189   PMID:10980193   PMID:12477932   PMID:14580338   PMID:14718928   PMID:15489334   PMID:17488291   PMID:19224922   PMID:23376485  


Genomics

Comparative Map Data
Arl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8725,007,401 - 25,018,572 (+)NCBIGRCr8
mRatBN7.2723,120,004 - 23,131,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl723,119,589 - 23,131,898 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx725,114,566 - 25,125,737 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,277,268 - 27,288,441 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,054,306 - 27,065,479 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,282,411 - 29,293,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,282,305 - 29,293,399 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0729,384,788 - 29,395,708 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,403,921 - 25,416,168 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1725,424,112 - 25,437,189 (+)NCBI
Celera720,279,124 - 20,290,252 (+)NCBICelera
Cytogenetic Map7q13NCBI
ARL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812101,393,116 - 101,407,820 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12101,393,116 - 101,407,772 (-)EnsemblGRCh38hg38GRCh38
GRCh3712101,786,894 - 101,801,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612100,311,045 - 100,325,703 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412100,289,381 - 100,304,040NCBI
Celera12101,452,210 - 101,466,869 (-)NCBICelera
Cytogenetic Map12q23.2NCBI
HuRef1298,846,985 - 98,861,641 (-)NCBIHuRef
CHM1_112101,752,887 - 101,767,477 (-)NCBICHM1_1
T2T-CHM13v2.012101,354,234 - 101,368,938 (-)NCBIT2T-CHM13v2.0
Arl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391088,566,720 - 88,579,956 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1088,566,720 - 88,579,956 (+)EnsemblGRCm39 Ensembl
GRCm381088,730,920 - 88,744,094 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1088,730,858 - 88,744,094 (+)EnsemblGRCm38mm10GRCm38
MGSCv371088,194,159 - 88,205,947 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361088,161,194 - 88,173,881 (+)NCBIMGSCv36mm8
Celera1090,711,447 - 90,723,221 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1044.19NCBI
Arl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540536,913,011 - 36,918,017 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540536,913,011 - 36,932,383 (-)NCBIChiLan1.0ChiLan1.0
ARL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210109,464,558 - 109,480,754 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112109,460,937 - 109,477,152 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01298,981,212 - 98,994,344 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112102,381,273 - 102,394,272 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12102,381,134 - 102,394,272 (-)Ensemblpanpan1.1panPan2
ARL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11540,390,091 - 40,401,043 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1540,390,890 - 40,401,060 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1540,758,710 - 40,769,658 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01541,044,924 - 41,055,878 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1541,041,767 - 41,055,853 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11540,300,430 - 40,311,369 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01540,409,187 - 40,420,136 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01540,683,467 - 40,694,418 (-)NCBIUU_Cfam_GSD_1.0
Arl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494519,573,506 - 19,585,419 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649212,583,887 - 12,595,798 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649212,583,878 - 12,595,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl582,796,121 - 82,815,936 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1582,795,741 - 82,812,153 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2586,794,413 - 86,804,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11196,662,260 - 96,674,662 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1196,659,769 - 96,675,486 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037148,327,574 - 148,343,169 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247506,516,531 - 6,523,671 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247506,516,511 - 6,522,759 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arl1
95 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:344
Count of miRNA genes:200
Interacting mature miRNAs:247
Transcripts:ENSRNOT00000007623
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat

Markers in Region
RH127965  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2723,131,667 - 23,131,859 (+)MAPPERmRatBN7.2
Rnor_6.0729,293,950 - 29,294,141NCBIRnor6.0
Rnor_5.0729,396,203 - 29,396,394UniSTSRnor5.0
RGSC_v3.4725,416,663 - 25,416,854UniSTSRGSC3.4
Celera720,290,748 - 20,290,939UniSTS
RH 3.4 Map7119.6UniSTS
Cytogenetic Map7q13UniSTS
BQ199867  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2723,118,213 - 23,118,370 (+)MAPPERmRatBN7.2
Rnor_6.0729,280,621 - 29,280,777NCBIRnor6.0
Rnor_5.0729,382,998 - 29,383,154UniSTSRnor5.0
RGSC_v3.4725,402,131 - 25,402,287UniSTSRGSC3.4
Celera720,277,334 - 20,277,490UniSTS
RH 3.4 Map7121.3UniSTS
Cytogenetic Map7q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007623   ⟹   ENSRNOP00000007623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,119,589 - 23,131,086 (+)Ensembl
Rnor_6.0 Ensembl729,282,305 - 29,293,399 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103837   ⟹   ENSRNOP00000092279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,121,638 - 23,131,898 (+)Ensembl
RefSeq Acc Id: NM_022385   ⟹   NP_071780
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,007,401 - 25,018,572 (+)NCBI
mRatBN7.2723,120,004 - 23,131,173 (+)NCBI
Rnor_6.0729,282,411 - 29,293,455 (+)NCBI
Rnor_5.0729,384,788 - 29,395,708 (+)NCBI
RGSC_v3.4725,403,921 - 25,416,168 (+)RGD
Celera720,279,124 - 20,290,252 (+)RGD
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_071780   ⟸   NM_022385
- UniProtKB: P61212 (UniProtKB/Swiss-Prot),   A6IFQ1 (UniProtKB/TrEMBL),   A0A8I6GK40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000007623   ⟸   ENSRNOT00000007623
RefSeq Acc Id: ENSRNOP00000092279   ⟸   ENSRNOT00000103837

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61212-F1-model_v2 AlphaFold P61212 1-181 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695131
Promoter ID:EPDNEW_R5656
Type:initiation region
Name:Arl1_1
Description:ADP-ribosylation factor like GTPase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0729,282,355 - 29,282,415EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621326 AgrOrtholog
BioCyc Gene G2FUF-34499 BioCyc
Ensembl Genes ENSRNOG00000005763 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007623.8 UniProtKB/TrEMBL
  ENSRNOT00000103837 ENTREZGENE
  ENSRNOT00000103837.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6889396 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64187 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72836 IMAGE-MGC_LOAD
NCBI Gene 64187 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11711 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arl1 PhenoGen
PRINTS SAR1GTPBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005763 RatGTEx
SMART ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6GK40 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UHY4_RAT UniProtKB/TrEMBL
  A6IFQ1 ENTREZGENE, UniProtKB/TrEMBL
  A6IFQ2_RAT UniProtKB/TrEMBL
  A6IFQ3_RAT UniProtKB/TrEMBL
  ARL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P41276 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Arl1  ADP-ribosylation factor like GTPase 1  Arl1  ADP-ribosylation factor-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Arl1  ADP-ribosylation factor-like 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Arl1  ADP-ribosylation factor-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the Golgi trans face 724590
gene_mutations_overexpression overexpression of mutant form T31N causes disappearance of the Golgi apparatus 724590